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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21710 results · page 310 of 724

Negative / Null Result ReportOpen accessMedicine

Effects of fermented palm kernel cake on growth performance, intestinal health, cecal microbiota, and ammonia emission in broilers.

Li J, Chen Z, Huang R et al. · 2026 · Poultry science

This study was conducted to evaluate the effects of fermented palm kernel cake (FPKC) on growth performance, intestinal health, cecal microbiota, nitrogen metabolism, and ammonia emission reduction of broiler chickens. A total of 900…

View details →DOI: 10.1016/j.psj.2026.107162
Negative / Null Result ReportMedicine

Obstetric and perinatal outcomes in twin pregnancies conceived through assisted reproduction: A retrospective cohort study.

Izbizky GH, Sevillano G, Abramor RM et al. · 2026 · Archivos argentinos de pediatria

Introduction. Multiple pregnancies are more frequently associated with adverse maternal and neonatal outcomes. The incidence of multiple pregnancies has increased with the use of assisted reproductive technologies (ART): they account for…

View details →DOI: 10.5546/aap.2025-10997.eng
Negative / Null Result ReportMedicine

Feasibility of Capillary Self-Collected Blood Specimens for Routine Outpatient Laboratory Testing.

Swartchick CB, Gurudu R, Lexvold NS et al. · 2026 · The journal of applied laboratory medicine

Background Capillary self-collection (CSC) devices allow patients to collect blood samples at home, potentially reducing outpatient phlebotomy visits. This study aimed to (a) assess the patient experience with multiple commercially…

View details →DOI: 10.1093/jalm/jfag075
Negative / Null Result ReportMedicine

[Experience of glutamine in parenteral nutrition in patients undergoing hematopoietic stem cell transplantation].

Alonso Domínguez MªT, Sánchez Navarro E, López López MJ et al. · 2026 · Nutricion hospitalaria

Introduction Introduction: hematopoietic stem cell transplantation (HSCT) is an aggressive and toxic procedure that can lead to malnutrition in patients. It has been proposed that these conditions may worsen under conditions of glutamine…

View details →DOI: 10.20960/nh.06172
Negative / Null Result ReportOpen accessMedicine

Variations in Pulse-Oxygen Saturation and Physical Development within the First 2 Hours after Birth Among Healthy Term Neonates Different Altitudes.

Du K, Yang YL, Li GY et al. · 2026 · Physiological research

This study aimed to examine early postnatal changes in pulse oxygen saturation (SpO2) and physical growth parameters during the first 2 hours following birth among healthy term neonates born at varying altitudes. A total of 963 healthy…

Negative / Null Result ReportMedicine

Effectiveness, Sex Differences, and Patient Experience in Real-World Use of Long-Acting Cabotegravir and Rilpivirine: Results from a Prospective Study.

González-Cordón A, Calvo J, Berrocal L et al. · 2026 · Infectious diseases and therapy

Introduction Long-acting intramuscular cabotegravir plus rilpivirine (LA-CAB/RPV) administered every 2 months (Q2M) has been available in Spain since January 2023 as a switch strategy for HIV treatment. We evaluated characteristics,…

View details →DOI: 10.1007/s40121-026-01373-w
Negative / Null Result Report

Feasibility study of dose calculation based on contrast-enhanced computed tomography for stereotactic body radiation therapy of lung metastases treated with MR-Linac

Zhao G, Liu M, Liu Y et al. · 2026 · Preprint

Abstract Background The reliability of contrast-enhanced CT (CHCT) as a reference image for MR-based dose calculation in lung stereotactic body radiation therapy (SBRT) with MR-Linac remains uncertain due to contrast-induced electron…

View details →DOI: 10.21203/rs.3.rs-9357535/v1
Failed Experiment ReportMedicine

Clinical benefit analysis of no tourniquet use in modified single-plane high tibial osteotomy: a retrospective cohort study.

Xue Z, Li X, Huang Y et al. · 2026 · BMC musculoskeletal disorders

Background Modified single-plane osteotomy is a modified technique of medial opening-wedge high tibial osteotomy (OWHTO). This study aimed to investigate the effects of tourniquet use versus non-use during modified single-plane high tibial…

View details →DOI: 10.1186/s12891-026-10055-0
Failed Experiment ReportOpen accessMedicine

The prognostic value of the Oocyte Maturation Index (OMI) on pregnancy outcomes in POSEIDON group 3 and 4 patients: a retrospective cohort study.

Bayram Y, Yildiz H, Ulger G et al. · 2026 · Journal of ovarian research

Background This study METHODS: A total of 662 patients treated at the Assisted Reproductive Techniques Unit of Mersin University Faculty of Medicine between 2016 and 2024 (Group 3: n=245; Group 4: n=417) were retrospectively analyzed.…

View details →DOI: 10.1186/s13048-026-02141-7
Failed Experiment ReportOpen accessMedicine

Accumulation of Heavy Metals in Blueberry Floral Rewards and Their Effects on Reproductive Fitness and Bumblebee Pollination Behavior.

Wu L, Sun Q, Wang X et al. · 2026 · Plants (Basel, Switzerland)

Heavy metals in soil can be translocated to floral rewards via specific physiological pathways, potentially altering pollinator behavior and reducing plant reproductive fitness. However, the comparative effects of different heavy metals on…

View details →DOI: 10.3390/plants15111656
Negative / Null Result ReportMedicine

The role of gender in patients with developmental dysplasia of the hip treated with closed reduction and spica cast immobilization: does it affect prognosis?

Kang Z, Li Y, Canavese F et al. · 2026 · Journal of pediatric orthopedics. Part B

To investigate the impact of gender on the prognosis of children with developmental dysplasia of the hip (DDH) treated with closed reduction and spica cast immobilization (CR-SCI). A retrospective analysis was conducted on 302 DDH children…

View details →DOI: 10.1097/bpb.0000000000001343
Negative / Null Result ReportOpen accessMedicine

Secretoneurin as a novel predictor of metabolic syndrome in patients with obstructive sleep apnea syndrome.

Arslan İ, Aslan Y, Arı M et al. · 2026 · Brazilian journal of otorhinolaryngology

Objective This study aimed to evaluate whether Secretoneurin (SN) was elevated in Metabolic Syndrome (MetS) and could serve as a potential predictive biomarker in the development of MetS in patients with Obstructive Sleep Apnea Syndrome…

View details →DOI: 10.1016/j.bjorl.2026.101856
Negative / Null Result ReportMedicine

The Effectiveness and Safety of Robotic-Assisted Bronchoscopy Across Diverse Patient Heights: A Subset Analysis of a Multicenter, Prospective, Observational Trial.

Gomes C, Gomes C, Cowan B et al. · 2026 · Journal of bronchology & interventional pulmonology

Background Outcomes of robotic-assisted bronchoscopy (RAB) in patients of small stature remain uncertain due to concerns about their potentially smaller lung volumes. We assess the effectiveness and safety of RAB across height variations.…

View details →DOI: 10.1097/lbr.0000000000001075
Negative / Null Result ReportMedicine

AI-assisted radiomics for classification of benign and non-benign right heart masses in 2D-echocardiography.

Chen Y, Deng M, Xie L et al. · 2026 · Journal of translational medicine

Background The rarity of right heart masses challenges diagnostic proficiency, while reproducibility is affected by the echocardiography operator. Artificial intelligence (AI)-based imaging tools may help address these limitations. Methods…

View details →DOI: 10.1186/s12967-026-08322-8
Negative / Null Result ReportMedicine

Lipid profile and angiogenic markers in the detection of preeclampsia: The RECLAMA study.

Ibarretxe D, Tameish S, González-Lleó A et al. · 2026 · Clinica e investigacion en arteriosclerosis : publicacion oficial de la Sociedad Espanola de Arteriosclerosis

Introduction and objectives Preeclampsia (PE) is a multisystem hypertensive disorder affecting 2-8% of pregnancies worldwide and represents a major cause of maternal and fetal morbidity and mortality. Its pathophysiology involves placental…

View details →DOI: 10.1016/j.arteri.2026.500946
Negative / Null Result ReportMedicine

Agreement of anterior segment measurements between Scheimpflug and swept-source OCT based instruments.

de la Torre JD, Blázquez Sanchez V, Bonnin Arias C et al. · 2026 · Journal francais d'ophtalmologie

Purpose To evaluate the differences and interchangeability of white-to-white (WTW) distance and anterior chamber depth (ACD) measurements among three devices: Anterion (Heidelberg Engineering, Heidelberg, Germany), IOL Master 700 (Carl…

View details →DOI: 10.1016/j.jfo.2026.104846
Negative / Null Result ReportOpen accessMedicine

Clinical outcomes of preimplantation genetic testing for structural rearrangements in couples with chromosomal inversions: a retrospective analysis.

Li Y, Keqie Y, Peng C et al. · 2026 · Frontiers in genetics

Chromosomal inversion is one of the common types of chromosomal structural rearrangements. For couples with chromosomal inversions, the appropriate recommendations for preimplantation genetic testing (PGT) remain a subject of ongoing…

View details →DOI: 10.3389/fgene.2026.1779551
Negative / Null Result ReportOpen accessMedicine

Evaluation of the Effectiveness and Color Stability of In-Office Bleaching Agents: A Retrospective Study.

Gönüllü İ, Devrimci EE, Singün B et al. · 2026 · Journal of clinical medicine

Background: The aim of this study was to evaluate the whitening efficacy and long-term stability of different in-office bleaching agents containing high concentrations of hydrogen peroxide (HP). Methods: Records of 50 patients who…

View details →DOI: 10.3390/jcm15093458
Negative / Null Result ReportMedicine

Effect of topical nanoemulsion of minoxidil on animal hair growth: an in vivo study.

Landi FS, Gholami M, Abdollahzadeh N et al. · 2026 · Journal of materials science. Materials in medicine

Topical minoxidil is typically administered over an extended period for the therapeutic management of androgenic alopecia. Given the adverse effects of commercial preparations of minoxidil (i.e., minoxidil solution), researchers are…

View details →DOI: 10.1007/s10856-026-07094-3
Negative / Null Result ReportOpen accessMedicine

Impact of different endometrial preparation protocols on pregnancy outcomes in frozen-thawed embryo transfer cycles among patients ≤35 years with a history of intrauterine adhesion separation surgery: a retrospective cohort study.

Sun H, Du M, Guo S et al. · 2026 · Frontiers in endocrinology

Objective To investigate the impact of three endometrial preparation protocols-hormone replacement therapy (HRT), natural cycle (NC), and down-regulation HRT-on pregnancy outcomes in frozen embryo transfer (FET) cycles among patients with…

View details →DOI: 10.3389/fendo.2026.1736841
Negative / Null Result Report

Immediate Effects of Dynamic and Rigid Taping on Static and Dynamic Plantar Pressure Distribution in Individuals with Hallux Valgus: A Cross-Over Study

Varhan B, Tanrıöğen B, Akpulat HMG et al. · 2026 · Preprint

Background: /Objectives: This study aimed to investigate the effects of different taping techniques commonly used in the management of hallux valgus (HV) on plantar pressure distribution under static and dynamic conditions. Methods: Thirty…

View details →DOI: 10.20944/preprints202606.1766.v1
Negative / Null Result ReportOpen accessMedicine

Associations of new intracranial haemorrhage, ischaemic stroke and survival with dual antiplatelet therapy regimen or duration after endovascular treatment for ruptured cerebral aneurysm.

Perng PS, Chang Y, Chuang MT et al. · 2026 · Stroke and vascular neurology

Background Dual antiplatelet therapy (DAPT) is often necessary following endovascular treatment for ruptured cerebral aneurysms; however, the optimal drug combination and treatment duration remain uncertain. Method Patients with…

View details →DOI: 10.1136/svn-2025-004362
Negative / Null Result ReportOpen accessMedicine

Association Between MTHFR Gene Polymorphisms and Subclinical Hypothyroidism in Early Pregnancy: A Retrospective Case-Control Study.

Liu L, Wang C, Chen X et al. · 2026 · International journal of women's health

Objective To investigate the association between methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms and subclinical hypothyroidism (SCH) in early pregnancy. Methods This retrospective case-control study included 100 pregnant…

View details →DOI: 10.2147/ijwh.s619071
Negative / Null Result ReportMedicine

[Effects of oliceridine versus sufentanil for anesthesia induction and postoperative analgesia on postoperative nausea and vomiting in patients undergoing gynecological laparoscopic surgery: a randomized controlled trial].

Wang Y, Xu X, Shen WJ et al. · 2026 · Zhonghua yi xue za zhi

Objective: To investigate the effects of oliceridine versus sufentanil for anesthesia induction and postoperative patient-controlled intravenous analgesia (PCIA) on postoperative nausea and vomiting (PONV) in patients undergoing…

View details →DOI: 10.3760/cma.j.cn112137-20260205-00404