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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21710 results · page 307 of 724

Negative / Null Result ReportMedicine

Connectedness to Nature, Ceremonial Participation, and Mental and Physical Health Among Rural and Urban Wixárika in Jalisco, Mexico.

Shattuck EC, McKinnon L, Herrera IR et al. · 2026 · American journal of human biology : the official journal of the Human Biology Council

Objectives Research in Western samples has repeatedly demonstrated a link between exposure to nature and natural stimuli and improved health. We sought to test these relationships in a sample of Indigenous Wixárika, whose traditional…

View details →DOI: 10.1002/ajhb.70298
Negative / Null Result ReportMedicine

Prevalence and risk factors of childhood anemia in urban and rural areas of West Java, Indonesia: a cross-sectional study.

Girsang RT, Dwi Putra MG, Rusmil K et al. · 2026 · BMC pediatrics

Background Anemia in children has become a serious global public health problem, which may lead to delayed growth and possibly have long term effects on neurodevelopmental and behavioral outcomes. Therefore, this study aimed to determine…

View details →DOI: 10.1186/s12887-026-06859-7
Negative / Null Result Report

Examining the Relationship Between Female Employment and Prenatal, Neonatal and Postneonatal Mortality Rates: An Interregional Analysis in Turkey

Kara VŞ, Acat Ö, Kocamanoğlu M · 2025 · Preprint

Abstract Background This study aimed to examine the relationship between female employment rates and perinatal, neonatal, and postneonatal mortality rates in different regions of Turkey. The role of women’s workforce participationin terms…

View details →DOI: 10.21203/rs.3.rs-7471725/v1
Negative / Null Result ReportMedicine

Prognostic factors and outcome measures after BRAF-directed targeted therapy of unresectable metastatic BRAF<sup>V600E</sup> colorectal cancer: a study cohort-level analysis.

Colloca GA, Venturino A · 2026 · Investigational new drugs

BRAF V600E mutation in metastatic colorectal cancer (mCRC) is associated with a poor prognosis. BRAF V600E inhibitors (BRAFi) plus EGFR inhibitors + / - MEK inhibitors regimens prolonged overall survival (OS), but prognosis remains…

View details →DOI: 10.1007/s10637-026-01607-1
Negative / Null Result ReportMedicine

The association of non-alcoholic fatty liver index, plasma metal levels, and genetic susceptibility using genome-wide type analysis.

Yu SH, Luo KH, Yang CC et al. · 2026 · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)

Background & aims This study aimed to explore the relationship between heavy metal exposure and the occurrence of non-alcoholic fatty liver disease (NAFLD), an area with conflicting existing research and unexplored genetic implications.…

View details →DOI: 10.1016/j.jtemb.2026.127891
Negative / Null Result ReportOpen accessMedicine

Earthquake-Related Anxiety and Earthquake Preparedness Plans of Medicine Students.

Yıldız M, Ergin Hıdıroğlu S · 2025 · Psychiatry and clinical psychopharmacology

Background Earthquakes are a significant natural disaster, particularly in regions where they occur frequently. Their psychological impact can lead to heightened anxiety, especially among individuals living in earthquake-prone areas. This…

View details →DOI: 10.5152/pcp.2025.241049
Negative / Null Result Report

Association of Sociodemographic Factors, Diabetes Mellitus, and Chronic Low Back Pain with Sarcopenia among Community-Dwelling Older Adults in West Jakarta, Indonesia

Widjaya CB, Kristian K, Handajani YS et al. · 2026 · Preprint

Abstract Background Sarcopenia is a geriatric syndrome characterized by progressive loss of skeletal muscle mass, strength, and physical performance, leading to disability and reduced quality of life. Several factors, including…

View details →DOI: 10.21203/rs.3.rs-8394782/v1
Negative / Null Result ReportMedicine

Association between shift work and periodontal disease in the Japanese manufacturing industry: A propensity score analysis.

Okubo H, Soyama Y, Kaneko N et al. · 2026 · Community dental health

Shift work is common in the manufacturing industry and is associated with an increased risk of chronic disease due to irregular lifestyles. However, the dental health status of shift workers has rarely been assessed or reported. Therefore,…

View details →DOI: 10.1177/0265539x261433765
Negative / Null Result ReportMedicine

Serial homicide offenders and the lunar cycle.

Salafranca Barreda D, González JA · 2026 · Chronobiology international

The purpose of this research is to establish whether there are factors that contribute to the predatory activation of serial homicide offenders (SHOs) in relation to the lunar cycles. In order to move the discussion away from the media…

View details →DOI: 10.1080/07420528.2025.2606282
Negative / Null Result ReportOpen accessMedicine

Exploring the role of ankle torque fluctuations and intramuscular coherence in gait function among older adults.

Yaguchi-Horiuchi A, Tsuji T, Takeuchi H et al. · 2025 · Aging clinical and experimental research

Objective This study aimed to investigate the relationship between ankle joint function and walking performance in older adults by assessing qualitative ankle functions through torque fluctuation analysis and tibialis anterior (TA)…

View details →DOI: 10.1007/s40520-025-03188-0
Negative / Null Result Report

The Evaluation of Inflammatory Biomarkers in Predicting the Severity and Steroid Responsiveness of Acute Graft versus Host Disease after Haplo- Identical Transplantation

Zakaria K, Khalaf MH, Soryal GB et al. · 2025 · Preprint

Abstract Background; Haematopoietic stem cell transplant (HSCT) is the transplant of stem cells usually derived from bone marrow, Peripheral blood, Umbilical cord, Matched sibling donor (HLA 6/6) , Or Haplo-Identical donor (HLA Matching…

View details →DOI: 10.21203/rs.3.rs-7568201/v1
Negative / Null Result ReportMedicine

The Impact of Operative Timing on Postoperative Complications in Laparoscopic Appendectomy for Uncomplicated Acute Appendicitis: A Retrospective Cohort Study.

Bozkurt H, Taşkın M, Özcan C et al. · 2026 · Journal of laparoendoscopic & advanced surgical techniques. Part A

Background Acute appendicitis (AA) is one of the most common surgical conditions presenting as acute abdomen. Delaying appendectomy can increase the risk of perforation. However, patients admitted or treated at night have been found to…

View details →DOI: 10.1177/10926429261428956
Failed Experiment ReportMedicine

Plate configuration in midshaft clavicle fractures: influence of working length, screw number, and plate length-a retrospective cohort study of 355 patients.

Hinkelmann MA, Schibler D, Frei F et al. · 2026 · European journal of orthopaedic surgery & traumatology : orthopedie traumatologie

INTRODUCTION: Midshaft clavicle fractures are commonly treated with plate fixation; however, the selected plate working length varies widely. Biomechanical principles suggest potential effects on fracture healing, but clinical evidence…

View details →DOI: 10.1007/s00590-026-04728-8
Failed Experiment Report

Size-advantage in nest-holding tactics in the dusky frillgoby Bathygobius fuscus males: mating success and parental care success but not fertilization success

Kawase S, Sato N, Yoshida M et al. · 2026 · Preprint

Abstract Body size is a critical trait influencing reproductive success through mate competition, female choice, and parental care ability. In fish species with alternative reproductive tactics, large males typically adopt dominant…

View details →DOI: 10.21203/rs.3.rs-8818992/v1
Negative / Null Result ReportMedicine

Composite dietary antioxidant index and cardiovascular diseases and all-cause mortality in Iranian adults: a prospective cohort study.

Farhadnejad H, Mokhtari E, Dianati Z et al. · 2026 · Nutrition, metabolism, and cardiovascular diseases : NMCD

Background and aims Antioxidants are known to combat oxidative stress, a key factor in the development of cardiovascular diseases(CVDs) and mortality. In the current study, we aimed to prospectively investigate the relationship between the…

View details →DOI: 10.1016/j.numecd.2026.104798
Negative / Null Result ReportOpen accessMedicine

Is Demographic Concordance Between Lifestyle Coach and Participant Associated With Participant Retention and Weight Change in the National Diabetes Prevention Program Lifestyle Change Intervention?

Smart BP, Forte A, Jacobs J et al. · 2026 · Journal of diabetes research

Objective The goal of this study is to explore the association between racial/ethnic, sex, and age category concordance and participant retention and weight loss among participants enrolled in the National Diabetes Prevention Program…

View details →DOI: 10.1155/jdr/7663175
Negative / Null Result ReportMedicine

The Relationship Between Neurofilament Light Chain and B Lymphocyte Chemoattractant and Cognition in Multiple Sclerosis.

Bakırcıoglu-Duman E, Petek-Balcı FB, Calıskan-Dolu N et al. · 2026 · Noro psikiyatri arsivi

Introduction Multiple sclerosis (MS) is a chronic inflammatory, autoimmune, demyelinating disease of the central nervous system that is often associated with cognitive impairment. This study aims to investigate whether Neurofilament light…

View details →DOI: 10.29399/npa.29126
Negative / Null Result ReportMedicine

Investigating the effect of probiotics on seizure-related symptoms in children with medication-resistant epilepsy: a randomized clinical trial.

Mohammadi M, Zahiroddin H, Mohammadi MS et al. · 2026 · Clinical neurology and neurosurgery

Introduction Antiseizure Medications (ASMs) can be beneficial for many patients with epilepsy; however, some individuals with medication-resistant epilepsy (MRE) may not experience effective seizure control. Although effective alternative…

View details →DOI: 10.1016/j.clineuro.2026.109445
Negative / Null Result ReportOpen accessMedicine

Effects of stand age on community composition and diversity of soil bacteria and fungi in poplar plantations in Northeast China.

Zhao L, Mao B, Wang H et al. · 2025 · Frontiers in plant science

Stand age is one of the most important indicators of plantation development status after afforestation. Soil microbial community plays an essential role in ecosystem functioning. Yet, the responses of soil microbial community composition…

View details →DOI: 10.3389/fpls.2025.1717501
Negative / Null Result ReportMedicine

Unmasking the Relationship Between Cyber Dating Abuse and Fear of Intimacy: Insights From a Cross-Sectional Study of Undergraduate Students.

Büyüktopaç Çakici H, Çiçek Gümüş E, Dişli E et al. · 2026 · Journal of interpersonal violence

The increasing digitalization of the world has led to a rise in cyber dating abuse among undergraduate students, who are transitioning into young adulthood and will be part of the future workforce. Additionally, identifying the…

View details →DOI: 10.1177/08862605251368917
Negative / Null Result ReportOpen accessMedicine

Cognitive deficits in individuals with comorbid personality disorder and schizophrenia: A scoping review.

Chalut A, Potvin S, Iozzino L et al. · 2026 · Schizophrenia research. Cognition

Objective It is estimated that approximately 40 % of individuals diagnosed with schizophrenia also meet the diagnostic criteria for a personality disorder. This comorbidity is associated with an unfavorable prognosis for the illness. Given…

View details →DOI: 10.1016/j.scog.2025.100403
Negative / Null Result ReportMedicine

Extending the UTAUT Model: The Role of Trust and Anthropomorphism in Shaping AI Acceptance in Medical Education in Iran.

Aghajani MS, Hatami J, Toofaninejad E · 2026 · Teaching and learning in medicine

Despite the widespread application of artificial intelligence (AI) in medical education, limited research has been conducted on the acceptance of this technology from medical students' perspectives. Therefore, this study aims to highlight…

View details →DOI: 10.1080/10401334.2025.2608190
Negative / Null Result ReportMedicine

The Relationship Between Biological Age and Emotional Intelligence in Young Swimmers.

Badzińska J, Żegleń M, Słowik J et al. · 2026 · American journal of human biology : the official journal of the Human Biology Council

Objectives Emotional intelligence is crucial for young athletes, affecting their psychosocial well-being and performance. Biological development, which includes physiological changes, is also important for athletes, affecting their…

View details →DOI: 10.1002/ajhb.70251