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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21710 results · page 300 of 724

Negative / Null Result ReportMedicine

Evaluating the Role of the Self-Assembling Topical Haemostat PuraBond in Periorbital Ecchymosis Associated with Osteotomies in Septorhinoplasty.

Rafay A, Beegun I, Joseph J · 2026 · Facial plastic surgery : FPS

Abstract Septorhinoplasty for both functional and cosmetic purposes is a widely performed operation. As with any surgical intervention, there are inherent risks that include bleeding manifesting as periorbital ecchymosis (PE). PuraBond is…

View details →DOI: 10.1055/a-2843-8884
Negative / Null Result ReportMedicine

Randomized communication nudges to increase primary care engagement among Medicaid enrollees in Maine.

Gordon SH, Nguyen KH, Biondi-Bonetti B et al. · 2026 · Health affairs scholar

Despite the importance of primary care in disease prevention, few studies have examined behavioral interventions to increase primary care engagement. In partnership with the Maine Department of Health and Human Services, we implemented a…

View details →DOI: 10.1093/haschl/qxag100
Failed Experiment ReportMedicine

Two fluffy family proteins, CgrFlbA and CgrFlbC, coordinately regulate hyphal growth, oxidative stress, asexual development, and pathogenicity in Colletotrichum graminicola.

Lin S, Wei H, Guo C et al. · 2026 · Microbial pathogenesis

Colletotrichum graminicola, the causal agent of maize anthracnose, is responsible for substantial global crop losses. While the fluffy family proteins (FlbA-FlbE, FluG) are known as key upstream activators of asexual development in…

View details →DOI: 10.1016/j.micpath.2026.108653
Failed Experiment ReportMedicine

Understanding and addressing oocyte maturation failure and failed or abnormal fertilization during oocyte-to-zygote transition.

Coticchio G, Taggi M, Innocenti F et al. · 2026 · Fertility and sterility

The transition from an immature oocyte to a normally fertilized zygote is a perilous bridge between gamete and embryo life. Failure can occur during oocyte maturation or in the multiple steps required for fertilization. In assisted…

View details →DOI: 10.1016/j.fertnstert.2026.06.001
Failed Experiment Report

Impact of salinity variation on periphyton development, growth performance, and survival of silver pompano (Trachinotus blochii)

Bhargavi R, Amirtharaj KSV, Athithan S et al. · 2026 · Preprint

Abstract In aquaculture systems, salinity has a significant impact on physiological function, water quality, and total productivity. This study used a periphyton-based system supported by split bamboo substrate to evaluate the survival and…

View details →DOI: 10.21203/rs.3.rs-9565935/v1
Failed Experiment ReportMedicine

Biocompatibility of printed, milled, and conventionally fabricated indirect resin-based restorative materials: an in vitro comparative study.

Atay A, Samiloglu DCA, Sismanoglu S et al. · 2026 · Odontology

The increasing use of digitally fabricated resin-based materials for definitive dental restorations has raised concerns regarding their biological performance and biocompatibility. This in vitro study evaluated the biocompatibility and…

View details →DOI: 10.1007/s10266-026-01432-1
Negative / Null Result Report

Influence of Patient-Related Factors and Surgeon Experience on Functional Outcomes in Conservatively Treated Proximal Humerus Fractures: A Retrospective Cohort Study

Pautasso A, Bernardi C, Assom M et al. · 2026 · Preprint

Abstract Purpose Proximal humerus fractures (PHFs) are common in the elderly population, but the optimal treatment strategy remains controversial. This study evaluated long-term functional outcomes of conservatively treated PHFs and…

View details →DOI: 10.21203/rs.3.rs-9669363/v1
Negative / Null Result ReportMedicine

Depressive Symptoms, Social Support, and Health-Related Quality of Life of Patients After Lung Transplantation.

Fan CH, Chen WH, Chou YH et al. · 2026 · Transplantation proceedings

Background Lung transplant recipients often experience depressive symptoms that can negatively impact their health-related quality of life (HRQOL). This study examined the relationship between depression and HRQOL, and whether social…

View details →DOI: 10.1016/j.transproceed.2026.05.015
Negative / Null Result ReportMedicine

A Personal Experience of Buccal Flaps for Cleft Palate Repair and the Effect of Buccal Flaps on Dentition.

McCrossan S, Francis EC, Graham F et al. · 2026 · The Journal of craniofacial surgery

Objective To assess the effect of buccal mucosal flaps for cleft palate (CP) repair on dental hygiene and eruption of the posterior molar teeth. Design A retrospective review of CP patients between 2008 and 2015 from our prospective (live)…

View details →DOI: 10.1097/scs.0000000000013017
Negative / Null Result ReportOpen accessMedicine

Serological response to feline coronavirus in the UK domestic cat population.

Sasvari H, Sherry L, Logan N et al. · 2026 · The Journal of general virology

Feline coronavirus (FCoV) is a ubiquitous virus of cats, with highly variable seroprevalence, ranging between 4 and 95% worldwide in the domestic cat population. It is the causative agent of feline infectious peritonitis (FIP), a disease…

View details →DOI: 10.1099/jgv.0.002270
Negative / Null Result ReportMedicine

Association of Polymorphisms of Inflammatory-Relevant Genes with Cancer Risk.

AlSrayea S, Alrashid MH, Bastaki NK et al. · 2026 · Current issues in molecular biology

Colorectal cancer (CRC) and non-Hodgkin lymphoma (NHL) are among the most prevalent cancer types globally by incidence and mortality. Both types are influenced differentially by chronic inflammation. Central to this inflammation are…

View details →DOI: 10.3390/cimb48060548
Negative / Null Result ReportMedicine

Assessing the Effectiveness of Multidisciplinary Interventions in Reducing Catheter-Associated Urinary Tract Infection: An Interrupted Time Series Modeling Approach.

Wills W, Rosever K, Bugajski A et al. · 2026 · Journal of nursing care quality

Background Recommendations support multi-interventional catheter-associated urinary tract infection (CAUTI) reduction programs; however, identifying specific interventions with significant impact may be beneficial in resource-limited…

View details →DOI: 10.1097/ncq.0000000000000956
Negative / Null Result ReportMedicine

Exploring the Mediating Role of Social Media and Gaming in the Relationship between Adolescents' Feelings of Loneliness, Ostracism and Internalizing and Externalizing symptoms.

Bruneel S, Sjöblom J, Lagerström M et al. · 2026 · Child psychiatry and human development

Social outsiderhood - particularly loneliness and ostracism - has a significant impact on mental health issues such as internalizing symptoms (e.g., depression, anxiety) and externalizing symptoms (e.g., aggression, conduct problems). Yet,…

View details →DOI: 10.1007/s10578-026-02027-1
Negative / Null Result ReportMedicine

Local hemodynamic changes and branch outcomes associated with inner branched versus outer branched stent grafts.

Erhart P, Bresler AM, Peters AS et al. · 2026 · Annals of vascular surgery

Background This study compared the hemodynamic performance and branch outcomes of outer branched (t-Branch) and inner branched (E-nside) stent-graft designs. Methods Patient-specific computational fluid dynamics (CFD) simulations were…

View details →DOI: 10.1016/j.avsg.2026.06.027
Negative / Null Result ReportMedicine

Evaluation of rotational profile and foot loading in the uninvolved leg of children with unilateral clubfoot treated with foot abduction orthoses.

Lawing CR, Bailey CE, Garg S et al. · 2026 · Journal of pediatric orthopedics. Part B

Ponseti treatment of congenital clubfoot utilizes foot abduction bracing to prevent recurrence. In unilateral clubfoot, families have expressed concern about inducing deformity in the uninvolved leg. This study evaluated rotational…

View details →DOI: 10.1097/bpb.0000000000001357
Negative / Null Result ReportMedicine

Impact of the COVID-19 pandemic on pediatric hemolytic uremic syndrome: Epidemiology, complications, and outcomes.

Jarosz-Wójcik E, Zajączkowski MA, Drożdż D et al. · 2026 · Advances in clinical and experimental medicine : official organ Wroclaw Medical University

Background Hemolytic-uremic syndrome (HUS) is a thrombotic microangiopathy that is most commonly caused by infection with Shiga toxin-producing Escherichia coli (STEC-HUS). Atypical HUS (aHUS) is associated with inappropriate activation of…

View details →DOI: 10.17219/acem/214976
Negative / Null Result ReportMedicine

Asymptomatic Nasal Carriage of MRSA Among Romanian Medical Students: Prevalence and Sampling Technique Comparison.

Dan MO, Aramă V, Rafila A et al. · 2026 · Microorganisms

Introduction Nasal colonization plays a pivotal role in Methicillin-resistant Staphylococcus aureus (MRSA) carriage and transmission, especially in healthcare settings. Asymptomatic carriers amongst healthcare workers (HCWs) may serve as…

View details →DOI: 10.3390/microorganisms14061265
Failed Experiment ReportMedicine

Impact of a home-based obesity prevention intervention on children's eating behaviours: Findings from the Guelph Family Health Study randomised controlled trial.

Jacob R, Walton K, Buchholz AC et al. · 2026 · Appetite

Children's eating behaviours are important determinants of childhood obesity; however, few studies have examined whether early childhood obesity prevention interventions influence these behaviours. This study investigated the impact of a…

View details →DOI: 10.1016/j.appet.2026.108609
Negative / Null Result ReportMedicine

Effect of a multifaceted hospital fluid conservation approach to intravenous fluid shortages on patient outcomes.

Xu O, Graven P, Downs S et al. · 2026 · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists

Purpose In September 2024, Hurricane Helene disrupted a key North Carolina facility producing 60% of medical-grade fluids in the United States, causing a nationwide intravenous fluid (IVF) shortage and prompting urgent conservation in…

View details →DOI: 10.1093/ajhp/zxag007
Negative / Null Result ReportMedicine

The impact of social participation on healthy ageing among Chinese middle-aged and older adults: The mediating role of life satisfaction.

Li B, Cheng L · 2026 · Applied psychology. Health and well-being

Healthy ageing is a major public health challenge in rapidly ageing societies, where longer life expectancy does not always translate into sustained well-being. This study examines health trajectories among Chinese middle-aged and older…

View details →DOI: 10.1111/aphw.70163