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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21287 results · page 294 of 710

Failed Experiment ReportOpen accessBiology

IMPACT OF BIO-FERTILIZER AND TIO2 NANOPARTICLES SPRAY ON GROWTH, PRODUCTIVITY AND PICKLE QUALITY OF TURNIP CROP (BRASSICA RAPA)

Mohamed Elsaggan, A. Shokry · 2019 · Egyptian Journal of Desert Research

he field work was carried out at the Experimental Farm of Desert Research Center at Siwa Oasis, Marsa Matrouh Governorate. During the two consecutive seasons of 2015/2016 and 2016/2017, the experiments were conducted to study the effect of…

View details →DOI: 10.21608/ejdr.2019.108099
Negative / Null Result ReportComputer Science

Can Modern NLP Systems Reliably Annotate Chest Radiography Exams? A Pre-Purchase Evaluation and Comparative Study of Solutions from AWS, Google, Azure, John Snow Labs, and Open-Source Models on an Independent Pediatric Dataset

Shruti Hegde, Mabon Ninan, Jonathan R. Dillman et al. · 2025 · arXiv.org

General-purpose clinical natural language processing (NLP) tools are increasingly used for the automatic labeling of clinical reports. However, independent evaluations for specific tasks, such as pediatric chest radiograph (CXR) report…

View details →DOI: 10.48550/arxiv.2505.23030
Negative / Null Result ReportOpen accessMedicine

Dose escalation in radical radio(chemo)therapy for cervical and upper thoracic esophageal cancer with 3DCRT/IMRT (ChC&UES): a multicenter retrospective study

Xiao-han Zhao, Wencheng Zhang, Xin Wang et al. · 2024 · Radiation Oncology

Cervical and upper thoracic esophageal cancer (ESCA) presents treatment challenges due to limited clinical evidence. This multi-center study (ChC&UES) explores radical radio(chemo)therapy efficacy and safety, especially focusing on…

View details →DOI: 10.1186/s13014-024-02521-7
Negative / Null Result ReportOpen accessMedicine

Three-year follow-up of changes of cortical bone thickness after implantation of Endo-Exo-Prosthesis (EEP) for transfemoral amputees

M. Örgel, E. Liodakis, Pratya Jaratjitwilai et al. · 2020 · Journal of Orthopaedic Surgery and Research

Introduction Transcutaneous Osseointegrated Prosthetic Systems (TOPS) offer a good alternative for patients who cannot be satisfactorily rehabilitated by conventional suspension sockets. The Endo-Exo-Prothesis (EEP, ESKA Orthopaedic…

View details →DOI: 10.1186/s13018-020-01675-w
Negative / Null Result ReportOpen access

The Effect of Endoscopic Peritubal Adenoidectomy Vs Myringotomy with Ventilation Tubes Insertion in Management of Otitis Media with Effusion in Children

M. El Begermy, Marwa M El Begermy, H. Kassamy · 2022 · Egyptian Journal of Ear Nose Throat and Allied Sciences

Background: There is a lot of controversy about the role of adenoidectomy and myringotomy with ventilation tubes insertion (MVT) in management of otitis media with effusion (OME). In a previous study we found that endoscopic-assisted…

View details →DOI: 10.21608/ejentas.2021.51633.1290
Negative / Null Result ReportBiology

Optimization of a vacuum-drying protectants for the biocontrol agent Pichia membranifaciens and its influence on viability and efficacy

Hongyan Zhang, Lili Deng, S. Yao et al. · 2020

Abstract In this study, we focused on screening for an optimal protectant formula for vacuum-dried Pichia membranifaciens and compared the biocontrol efficacy of fresh P. membranifaciens and dried one on citrus fruit. We also used several…

View details →DOI: 10.1016/j.biocontrol.2019.104155
Negative / Null Result ReportOpen access

Comparative evaluation of photoactivated disinfection and sonic irrigation as an adjunct to conventional irrigation on Enterococcus faecalis in root canals: An in vitro study

Tushar Kohli, N. Mehta, G. Garima et al. · 2021

Objective: The aim of the in vitro study was to compare the antibacterial efficacy of photoactivated disinfection (PAD), sonic irrigation as an adjunct to conventional irrigation against Enterococcus faecalis in vitro. Materials and…

View details →DOI: 10.4103/endo.endo_12_20
Negative / Null Result ReportMedicine

Interplay Among Reward Processing, Schizotypal Traits, and Psychosocial Stress in a Large Chinese Young Adult Sample: A Cross‐Sectional Network Analysis

Donghao Tuo, Yi-hang Huang, Simon S. Y. Liu et al. · 2026 · PsyCh Journal

ABSTRACT Reward processing comprises reward sensitivity, motivation, and pleasure experience, but how these components jointly relate to schizotypal traits and psychosocial stress in young adult samples remains unclear. Using network…

View details →DOI: 10.1002/pchj.70102
Negative / Null Result ReportMedicine

Glutathione S-transferase expression in benign and malignant eyelid tumors

Efe Saygın, R. Karadag, S. Ozkanlı et al. · 2021 · Biotechnic & Histochemistry

ABSTRACT Eyelid tumors commonly originate from the skin and its appendages. Environmental toxins and oxidants affect eyelid carcinogenesis. Glutathione S-transferases (GST) are antioxidants that participate in pathogenesis. We investigated…

View details →DOI: 10.1080/10520295.2021.1986133
Negative / Null Result ReportOpen accessMedicine

Vaccination counseling with and without excipient skin testing in patients with suspected allergic reactions to mRNA COVID-19 vaccines and patients with atopy

Dilawar Khokhar, K. O’Shea, C. Akin et al. · 2022 · Journal of Allergy and Clinical Immunology: Global

Background Allergic reactions have been reported with mRNA vaccines for COVID-19 prevention. Patients perceived to be at higher risk for a reaction may be referred to an allergist, although evaluation strategies may differ between…

View details →DOI: 10.1016/j.jacig.2022.05.012
Negative / Null Result ReportMedicine

Exploratory safety investigations in normal, freely moving Göttingen minipigs using telemetry: Pharmacological validation.

Julie Jacobsen, Berit Ø. Christoffersen · 2025 · Journal of pharmacological and toxicological methods

INTRODUCTION Adverse cardiovascular (CV) effects is a major cause of drug attrition. Early assessment of CV risk for new drug candidates may be warranted for early de-risking of the further development. Predictive animal models and a…

View details →DOI: 10.1016/j.vascn.2025.108395
Negative / Null Result ReportOpen accessMedicine

Evaluation of Health Literacy and Associated Factors Among Adults Living in Saudi Arabia: A Cross-Sectional Study

Yaser M. Alahmadi · 2023 · Inquiry : a journal of medical care organization, provision and financing

In this westernized culture, maintaining a healthy lifestyle has become a major health concern internationally. Health literacy is an emerging concept and requires effective measures and reform to improve the health status and health of…

View details →DOI: 10.1177/00469580231161428
Negative / Null Result ReportOpen accessMedicine

Natamycin versus natamycin combined with voriconazole in the treatment of fungal keratitis

Jingjing Cai, Chengwen Yang, Qiuhong Wei et al. · 2023 · Pakistan Journal of Medical Sciences

Objective: To observe the therapeutic effect of natamycin combined with voriconazole in the treatment of fungal keratitis (FK). Methods: This is a retrospective study. The subjects of this study were 64 patients with FK who were admitted…

View details →DOI: 10.12669/pjms.39.3.6908
Negative / Null Result ReportMedicine

PP27 Pre-hospital lactate monitoring: a worthy adjunct to systolic blood pressure and shock index in triggering blood product administration in patients with suspected traumatic haemorrhage?

J. Griggs, M. Sherriff, J. Leung et al. · 2019 · Emergency Medicine Journal

Introduction Pre-hospital identification of patients with suspected occult traumatic haemorrhage is problematic. Physiological parameters and clinical gestalt are inadequate surrogates for ongoing haemorrhage. Lactate monitoring may hold…

View details →DOI: 10.1136/emermed-2019-999.27
Negative / Null Result ReportMedicine

AAV2-hCHM Subretinal Delivery to the Macula in Choroideremia: Two Year Interim Results of an Ongoing Phase I/II Gene Therapy Trial.

T. Aleman, Rachel M. Huckfeldt, Leona W. Serrano et al. · 2022 · Ophthalmology (Rochester, Minn.)

PURPOSE To assess the safety of the subretinal delivery of a recombinant adeno-associated virus serotype 2 (AAV2) vector carrying a human CHM-encoding cDNA in choroideremia (CHM). DESIGN Prospective, open-label, non-randomized,…

View details →DOI: 10.1016/j.ophtha.2022.06.006
Negative / Null Result ReportOpen accessMedicine

Potential effects of angiogenesis-related factors on the severity of APAC and surgical outcomes of trabeculectomy

Jing Wang, Ming-shui Fu, Min Zhou et al. · 2020 · BMC Ophthalmology

Background EPO (erythropoietin) and PDGF (platelet derived growth factor) families are thought to be associated with angiogenesis under hypoxic condition. The sharp rise of intraocular pressure in acute primary angle closure (APAC) results…

View details →DOI: 10.1186/s12886-021-02051-w
Negative / Null Result ReportMedicine

Magnetic resonance imaging-based detection of retinal hemorrhages in a multicenter cohort of abusive head trauma

M. Hahnemann, B. Karger, S. Banaschak et al. · 2026 · Pediatric Radiology

Background In pediatric abusive head trauma (AHT), retinal hemorrhages are a key diagnostic feature. Detection by fundoscopy may be delayed or limited, whereas magnetic resonance imaging (MRI) enables non-invasive, objective assessment on…

View details →DOI: 10.1007/s00247-026-06558-6
Negative / Null Result ReportOpen accessGeography

An Empirical Study on Different Tendencies toward Indulgence-Restraint Dimension from the Intercultural Perspective —In the Case of Guangdong Province

Cai Jie, L. Jing · 2015

With the booming development of economic globalization nowadays, intercultural communication becomes more and more important. Based on Hofstede’s indulgence-restraint dimension, this thesis aims to testify whether Hofstede’s opinion that…

View details →DOI: 10.4236/chnstd.2015.44017
Negative / Null Result ReportOpen accessMedicine

Differences in social perception in people with schizophrenia and bipolar disorder

Álvaro Cavieres, Vanessa Acuña, M. Arancibia et al. · 2023 · Schizophrenia Research: Cognition

People with schizophrenia have difficulties recognizing other people's expressions, emotional states, and intentions; however, much less is known about their ability to perceive and understand social interactions. We used scenes depicting…

View details →DOI: 10.1016/j.scog.2023.100286
Negative / Null Result ReportOpen accessMedicine

Effect of daily versus intermittent iron therapy in pregnant women: hematological and pregnancy outcome

S. K. Agrawal, M. Jindal · 2020 · Obsgyne Review: Journal of Obstetric and Gynecology

Background: The purpose of this study was to compare daily iron supplementation and intermittent iron supplementation in preventing anemia in healthy pregnant women. Material and Method: Prospective Randomized Clinical Trial. From May 2004…

View details →DOI: 10.17511/joog.2020.i03.01
Negative / Null Result ReportOpen access

Use of boron sources and doses in the industrial tomato under irrigation

R. D. da Silva · 2023 · Pakistan Journal of Agricultural Sciences

Boron sources and doses can positively increase fruit quality and tomato yield. This study aimed to evaluate the influence of boron doses and sources on the development and yield of industrial tomatoes under irrigation. A randomized block…

View details →DOI: 10.21162/pakjas/23.1002