A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21287 results · page 290 of 710
Ouazzani S, Lemmers A, Boskoski I et al. · 2026 · Obesity surgery
Background Endoscopic sleeve gastroplasty (ESG) is an established endoscopic bariatric therapy. Two main platforms are currently used in clinical practice: the OverStitch Endoscopic Suturing System (OESS) and the triangulation Endomina…
He M, Wang L, Zhang S et al. · 2026 · Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)
Purpose To investigate the effect of nightly 0.01% atropine eye drops on choroidal thickness (ChT) in pre-myopic children (at risk of myopia). Methods In a 12-month randomised, double-blind, placebo-controlled trial, 54 children aged 5-12…
Masoud M, El-Assal MA, Ibrahim MA et al. · 2026 · International orthopaedics
Background The peroneus longus tendon (PLT) has emerged as a promising graft option for anterior cruciate ligament reconstruction (ACLR), with acceptable outcomes; however, concerns have been raised about potential donor-site morbidity,…
Zhang Y, Wang Y, You S et al. · 2026 · Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Background White matter hyperintensities (WMHs) are associated with an increased risk of stroke, cognitive decline, and all-cause mortality. However, the relationship between cardiac function, particularly left ventricular ejection…
Davide S, Domenico M, Fabio C et al. · 2026 · European journal of dental education : official journal of the Association for Dental Education in Europe
Introduction Suturing is a crucial step in oral surgery, directly affecting wound healing quality. Simple interrupted suture is widely used in dentistry, often performed by novices using silk sutures due to their ease of use and low cost.…
Guan J, Chen Y, Ye J et al. · 2026 · Annali italiani di chirurgia
Aim Rotator cuff tears and long head of the biceps tendon (LHBT) injuries are primary causes of shoulder pain. During rotator cuff repair, concurrent LHBT injuries are frequently identified. Surgical management of LHBT injuries can…
Phyo AP, Hoglund RM, Saito M et al. · 2026 · Tropical medicine & international health : TM & IH
Background HIV co-infection affects host responses and pharmacokinetics (PK) of tuberculosis (TB) treatment. This study assessed the PK of first-line anti-TB drugs and clinical outcomes in patients with and without HIV co-infection.…
Nicklas A, Bienger K, Rudari M et al. · 2026 · Burns : journal of the International Society for Burn Injuries
Background Split-thickness skin grafting (STSG) remains the standard for deep second-degree burns, but grafted skin often shows suboptimal biomechanical properties. The dermal substitute MatriDerm® may improve elasticity, structural…
Deml O, Schenk P, Fritsche C et al. · 2026 · Journal of shoulder and elbow arthroplasty
Background Geriatric distal humerus fractures are difficult to manage. Open reduction and internal fixation remain the standard, but total elbow arthroplasty (TEA) appears to be a viable alternative. This study evaluated the long-term…
Jiang D, Zhang W, Liu L et al. · 2026 · BMC cardiovascular disorders
Background Accurate quantification of aortic valve calcification (AVC) on contrast-enhanced computed tomography angiography (CTA) is pivotal for planning surgical and transcatheter aortic valve replacement. The optimal Hounsfield unit (HU)…
liu p, Hu S, Zeng H et al. · 2026 · Preprint
Abstract Background : Timely reperfusion is critical for patients with acute ST-segment elevation myocardial infarction (STEMI). While door-to-balloon (D2W) time has been substantially optimized in chest pain centers, the impact of first…
Arnouts EC, Drysdale ND, Gerstner Saucedo J et al. · 2026 · Pediatric radiology
Background Diffuse myocardial fibrosis, as measured by T1 (longitudinal relaxation time) mapping and extracellular volume, may be associated with ventricular dysfunction in the Fontan circulation. However, the relationship between diffuse…
Hadi M, Natashia D, Purwati NH et al. · 2026 · Nurse education today
Background Effective interprofessional collaboration is essential for optimal patient care, but inadequate training often hinders teamwork and communication among healthcare professionals. Interprofessional Education (IPE) can address this…
Levent M, Akın S · 2026 · BMC geriatrics
Background Malnutrition drives adverse outcomes in older adults, but routine screening is often hindered by time constraints and reliance on subjective data. The Geriatric Nutritional Risk Index (GNRI), derived from serum albumin and body…
Yang H, Yang L, Li Z et al. · 2025 · Medicine
Observational studies have reported associations between coffee intake and osteoarthritis (OA), rheumatoid arthritis (RA), and osteoporosis (OP). However, it remains unknown whether these relationships are causal. In this study, we applied…
Yamamoto J, Nakamura K, Hayama H et al. · 2026 · Cardiology
Whether the mortality impact of ischemic stroke and major bleeding differs across left ventricular ejection fraction (LVEF) categories in patients hospitalized for acute heart failure (AHF) with atrial fibrillation (AF) remains uncertain.…
Ricketts TA, Krivoshey R, Santos-Garrido J et al. · 2026 · Journal of speech, language, and hearing research : JSLHR
Purpose The purpose of this study was to evaluate the effects of loudspeaker configuration and relative dialogue-to-background sound levels on subjective ratings of speech understanding and sound quality of recorded media for listeners…
Jee J, Zhang J, Lavery JA et al. · 2026 · Cancer discovery
Real-world data suggest that SARS-CoV-2 mRNA vaccines, administered within 100 days of immune checkpoint inhibitor (ICI) treatment ("peri-ICI vaccination"), may improve ICI effectiveness through synergistic immune priming. In an…
Maynart V, Menezes P, Batista C et al. · 2026 · Ear and hearing
Abstractobjectives The purpose of this experiment was to determine the effects of sequential sounds on cortical auditory evoked potentials and to investigate temporal masking. The study tested the hypotheses that forward masking reduces…
Li X, Zhang Y, Chen S · 2026 · Journal of counseling psychology
This study examined how clients' outcome expectations (OE; belief about positive outcome of counseling session) was associated with working alliance and symptom relief longitudinally in a sample of Chinese beginning therapist trainees and…
Peters EM, Quadri A, Aziz S et al. · 2026 · Journal of affective disorders
The purpose of this study was to examine the effects of two patient-level factors, episode duration and severity, on placebo response in antidepressant clinical trials. To do this we conducted a secondary analysis of seven 8-week,…
Lee JH · 2026 · Preprint
Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and irritable bowel syndrome (IBS) frequently co-occur following infection, yet shared genetic architecture at the locus level has not been systematically…
Yan Z, Tian Y, Huang Y et al. · 2026 · Psychopathology
Introduction Distraction response style, neuroticism, and parental conflict have been linked to rumination in adolescents with subthreshold depression. However, whether these associations differ by gender remains unclear. Methods This…
Su C, Lu T · 2026 · Preprint
Background Heart failure (HF) and body mass index (BMI) share substantial genetic architecture, which may lead genetically informed target discovery to preferentially identify adiposity-related pathways. We sought to identify circulating…
Howard L, Hawn S, Pitchford KD et al. · 2026 · Behavioral sciences (Basel, Switzerland)
The denial, concealment, or omission of disordered eating behaviors has received limited attention in the eating disorder literature, partly due to the lack of reliable and valid measures. This study re-examined the factor structure of the…
Saengsin K, Jirattikanwong N, Wongyikul P et al. · 2026 · Journal of clinical medicine
Background/Objectives : Post-extubation stridor (PES) is common in pediatric critical care and may contribute to extubation failure, particularly in children with heart disease. Prophylactic corticosteroids are frequently used before…
Figureau T, Priolo D, Sleegers WWA et al. · 2026 · Preprint
Cognitive dissonance, traditionally conceptualized as a fundamental psychological process involving discomfort from inconsistent cognitions, may vary across cultures. These variations could be attributed to self-construal, or how…
Espeche W, Minetto J, Cerri G et al. · 2026 · Hypertension research : official journal of the Japanese Society of Hypertension
Hypertensive disorders of pregnancy are a leading cause of maternal-fetal morbidity and mortality, with preeclampsia representing a major contributor to adverse outcomes. Ambulatory blood pressure monitoring (ABPM) has improved risk…
Vollam S, Roman C, Santos M et al. · 2026 · JMIR medical informatics
Background Many studies have evaluated the use of wearable monitoring systems to improve patient safety in hospital. Although some have demonstrated effects on intensive care admissions, there remains little evidence of impact on patient…
Appiah KN, Sharma N, Adu N et al. · 2026 · Preprint
Abstract Background: Anthracycline-based chemotherapy produces progressive functional decline and cardiotoxicity in adults with cancer. Physical activity interventions may attenuate these effects, yet evidence across multiple domains…