Negative / Null Result ReportMedicine
Dupla X, Bertagni MB, Grand S · 2025 · Environmental science & technology
Enhanced rock weathering (ERW) is a CO 2 removal technology that involves spreading finely ground silicate rock on fields. The chemical weathering of this rock powder removes atmospheric CO 2 in the form of bicarbonate ions and secondary…
View details →DOI: 10.1021/acs.est.5c09820 Negative / Null Result ReportMedicine
Hernigou P, Caton J · 2025 · International orthopaedics
Purpose Calcium pyrophosphate dihydrate (CPPD) deposition, often visible radiographically as chondrocalcinosis, frequently accompanies knee osteoarthritis and is usually encountered at the time of arthroplasty. Whether its presence…
View details →DOI: 10.1007/s00264-025-06663-5 Negative / Null Result ReportMedicine
Grummon AH, Zeitlin AB, Lee CJY et al. · 2026 · American journal of preventive medicine
Introduction As of 2025, 9 states have adopted Universal Free School Meal programs. The success of these programs depends in part on high participation. This study tested whether a social media campaign promoting school meal participation…
View details →DOI: 10.1016/j.amepre.2025.108232 Failed Experiment ReportOpen accessMedicine
McLachlan SA, Hall I, Collins A et al. · 2026 · Psycho-oncology
Background Circulating tumor DNA (ctDNA) is a novel prognostic biomarker indicating minimal residual disease and high recurrence risk. In three randomised DYNAMIC trials, ctDNA was used to guide adjuvant chemotherapy (ACT) for early-stage…
View details →DOI: 10.1002/pon.70464 Failed Experiment Report
Lin Y, Westgate EC · 2025 · Preprint
Why don’t people go to bed on time? Most research on bedtime procrastination has focused on individual differences (e.g., self-regulation, chronotype), potentially conflating between-person patterns with within-person mechanisms. To…
View details →DOI: 10.31234/osf.io/qtxb4_v1 Failed Experiment ReportOpen accessMedicine
Hokamura N, Fukagawa T, Fukushima R et al. · 2025 · Cancers
Background Radiotherapy (RT) combined with immune checkpoint inhibitors (ICIs) has shown therapeutic benefits, and the potential for enhanced immune activation has raised concerns about increased immune-related adverse events (irAEs). The…
View details →DOI: 10.3390/cancers17243992 Failed Experiment Report
Wood C, Smith Z, Johnson L et al. · 2025 · Preprint
ABSTRACT The “fate of naked DNA” or “environmental DNA (eDNA)” from genetically engineered (GE) biomasses in relation to possible horizontal gene transfer (HGT) is an emerging area of biosafety research. Using a broad-host plasmid…
View details →DOI: 10.1101/2025.11.21.689801 Negative / Null Result ReportOpen accessMedicine
Sazuka T, Habu Y, Matsusaka K et al. · 2026 · International journal of clinical oncology
Background Pelvic lymph-node dissection is performed across multiple surgical specialties. However, inconsistent terminology and unclear anatomical boundaries hinder standardization. This study established a multidisciplinary team with a…
View details →DOI: 10.1007/s10147-026-02993-5 Negative / Null Result ReportMedicine
Hamrick MW, Fulzele S, Isales CM et al. · 2025 · Biochimie
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that is thought to play important roles in aging, oxidative stress, and cellular senescence. We have previously shown that the AhR agonist kynurenine (Kyn), a…
View details →DOI: 10.1016/j.biochi.2025.11.010 Negative / Null Result ReportMedicine
Busse A, Müller J, Benbow ME et al. · 2025 · Journal of Applied Entomology
Understanding the dispersal ability of insects is critical for conservation efforts, as well as for preventing economic and health risks, such as the spread of bluetongue disease or African swine fever (ASF). However, knowledge of the…
Negative / Null Result ReportMedicine
de Faria OAC, Kussano NR, de Faria LC et al. · 2026 · Reproduction in domestic animals = Zuchthygiene
This study aimed to evaluate whether the quality of injection and number of oocytes injected during Intrafollicular Transfer of Immature Oocytes (IFIOT) affect ovulation timing, follicle dynamics, oocyte recovery, nuclear maturation and in…
View details →DOI: 10.1111/rda.70182 Negative / Null Result ReportMedicine
Ng PH, St-Hilaire S · 2025 · Diseases of aquatic organisms
Microcystis spp. blooms in fish ponds can lead to fluctuations in water parameters, and the microcystin-LR (MC-LR) toxin they produce may pose health risks for fish, as well as consumers. Hydrogen peroxide (H2O2) treatment has been…
View details →DOI: 10.3354/dao03875 Negative / Null Result ReportMedicine
Klaassen AD, Willigenburg NW, Musters JWQ et al. · 2026 · The Journal of bone and joint surgery. American volume
Background Hip dislocation is the most common reason for early revision after total hip arthroplasty (THA). To prevent dislocation, patients are often prescribed movement restrictions following THA; however, these restrictions can be…
View details →DOI: 10.2106/jbjs.25.00121 Negative / Null Result ReportMedicine
Xie Z, Yang C, Yin Y et al. · 2025 · Heart (British Cardiac Society)
Background Intensive blood pressure (BP) control Methods This is a post hoc analysis of the China Rural Hypertension Control Project. Mixed-effect Cox proportional regression and generalised estimating equation models were used to…
View details →DOI: 10.1136/heartjnl-2025-326413 Negative / Null Result Report
Boito L, Rijnders J, Steinwidder L et al. · 2025 · Preprint
Abstract Enhanced weathering (EW) of silicate minerals has emerged as a promising carbon dioxide removal (CDR) strategy, with potential benefits for soil fertility and crop performance. However, the soil processes that determine these…
View details →DOI: 10.1101/2025.11.03.686277 Negative / Null Result ReportMedicine
Chandan Reddy S, Mao T, Gendreau J et al. · 2026 · Clinical neurology and neurosurgery
Objective Oligodendrogliomas are typically benign tumors that arise within the white matter tracts of the cerebral hemispheres. Surgical resection, radiotherapy (RT), and chemotherapy (CT) are utilized to prolong survival in patients…
View details →DOI: 10.1016/j.clineuro.2025.109279 Negative / Null Result ReportMedicine
Davila-Piñón P, Díez-Martín AI, Nogueira-Rodríguez A et al. · 2026 · Endoscopy
Background and study aim The impact of computer-aided detection (CADe) systems remains uncertain. We evaluated whether PolyDeep, a CADe system, improves adenoma detection rate (ADR) in a colorectal cancer (CRC) screening program. Patients…
View details →DOI: 10.1055/a-2895-1613 Negative / Null Result ReportMedicine
de Lint L, de Vries R, van Rookhuijzen M et al. · 2026 · Appetite
Food choices are not made within a vacuum but depend upon earlier decisions, resulting in spillover effects where subsequent choices are either similar (consistency) or contrasting (balancing). Little is known about spillovers in…
View details →DOI: 10.1016/j.appet.2025.108394 Negative / Null Result ReportMedicine
Pervane YD, Bağlan E · 2025 · Expert opinion on biological therapy
Objective Biologic agents have been used in colchicine-resistant familial Mediterranean fever (FMF) patients and in patients with comorbidities including juvenile idiopathic arthritis (JIA). The main aim of our study was to evaluate the…
View details →DOI: 10.1080/14712598.2025.2576511 Negative / Null Result ReportMedicine
Savin Z, Ben-David R, Shem-Tov Dlugy A et al. · 2025 · Canadian Urological Association journal = Journal de l'Association des urologues du Canada
Introduction Active surveillance (AS) requires regular monitoring to detect disease progression. Multiparametric magnetic resonance imaging (mpMRI) and targeted biopsies are commonly used to identify clinically significant prostate cancer…
View details →DOI: 10.5489/cuaj.9254 Negative / Null Result ReportMedicine
Collins SF, Soliz L, Tucker G et al. · 2025 · Science of the Total Environment
Here, we assessed patterns of microplastics (MP; particles <5 mm) and microfibers (MF; fibers <5 mm) within benthic macroinvertebrates and fishes collected from a polluted urban stream (10-km segment; n = 5 reaches; 200-m reach lengths).…
Negative / Null Result ReportMedicine
Akiyama H, Sasaki Y, Tago K et al. · 2025 · Agriculture, Ecosystems and Environment.
Previous studies have reported that nitrification inhibitors are effective in reducing nitrous oxide emissions. However, no studies have reported the effectiveness of 3,4-dimethylpyrazole phosphate, and 3,4-dimethylpyrazole succinic acid…
Negative / Null Result ReportMedicine
Vavricka SR, Zeitz J, Madanchi M et al. · 2025 · The American journal of gastroenterology
Introduction Retrospective data suggest association of high-altitude exposure and inflammatory bowel disease flares. Knowledge about underlying pathogenesis remains limited. Methods This prospective interventional trial evaluated the…
View details →DOI: 10.14309/ajg.0000000000003888 Negative / Null Result ReportMedicine
Hammett JF, Kirwan M, Chen W · 2026 · Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors
Objective Intimate partner violence (IPV) is a major public health concern. Heavy episodic drinking (HED; i.e., drinking 5+ drinks for men or 4+ drinks for women in a 2-hr period) is a contributing cause of IPV, yet HED does not elicit IPV…
View details →DOI: 10.1037/adb0001108 Negative / Null Result ReportMedicine
Savran F, Bayram F, Küçük F · 2026 · The Journal of craniofacial surgery
Objective This study aimed to evaluate the effects of intravenous dexamethasone and tranexamic acid (TXA), used alone and in combination, on perioperative bleeding and postoperative edema and ecchymosis in rhinoplasty. Methods In this…
View details →DOI: 10.1097/scs.0000000000012092 Negative / Null Result ReportMedicine
Lipps KM, Samuel AM, Patel D et al. · 2025 · Journal for healthcare quality : official publication of the National Association for Healthcare Quality
Background Hypertension (HTN) is common in the inpatient setting, with many patients receiving as-needed (PRN) antihypertensive medications (anti-HTN) despite lack of benefit and risk of adverse events. We aimed to decrease PRN anti-HTN…
View details →DOI: 10.1097/jhq.0000000000000473 Negative / Null Result ReportMedicine
Qasim MSA, Kang P, Evans B et al. · 2026 · Contact lens & anterior eye : the journal of the British Contact Lens Association
Purpose To investigate the utility of in vivo confocal microscopy (IVCM) combined with standardized image grading for identifying early morphological changes in the central corneal and superior limbal basal epithelial cells during…
View details →DOI: 10.1016/j.clae.2026.102667 Negative / Null Result Report
de Paulo MC, Aguiar LM, Ferreira NMC et al. · 2026 · Preprint
Background Lauric acid (LA) is a medium-chain saturated fatty acid found in several foods, including vegetable oils and seeds. Previous studies have demonstrated that LA exhibits neuroprotective, antioxidant, and anti-inflammatory…
View details →DOI: 10.64898/2026.05.15.725442 Negative / Null Result Report
Hehl M, Toyonaga T, Carson RE et al. · 2026 · Preprint
Abstract Introduction: In animal neurophysiology, motor learning induces long-term potentiation- and depression-like plasticity, i.e., the strengthening or weakening of connections between neurons. In humans, gray matter volume (GMV)…
View details →DOI: 10.21203/rs.3.rs-8957106/v1 Negative / Null Result ReportOpen accessMedicine
Alenezi BM, Khoyratty F, Biswas S et al. · 2026 · Translational vision science & technology
Purpose To investigate the effect of corneal cross-linking (CXL) on corneal curvature and thickness in two different keratoconic populations, one based in the Middle East (Saudi Arabia) and one in Europe (UK), and to explore whether age…
View details →DOI: 10.1167/tvst.15.3.12 