Replication FailureMedicine
Batashvili M, Israel BH, Levy DA et al. · 2026 · International journal of psychophysiology : official journal of the International Organization of Psychophysiology
Tactile texture memory has been underexplored compared to visual and auditory memory, despite its importance in daily functioning. Prior research indicates that theta oscillations support memory consolidation across modalities, and frontal…
View details →DOI: 10.1016/j.ijpsycho.2025.113318 Replication Failure
Rain AZ, Sundararaghavan HG, Ji K · 2025 · Preprint
Midkine (MDK) is a heparin-binding growth factor that promotes tumor growth in many cancers and may contribute to type I neurofibromatosis (NF1) tumor by stimulating Schwann cell proliferation and supporting neurofibroma growth. Here, we…
View details →DOI: 10.1101/2025.10.20.683475 Negative / Null Result ReportOpen accessMedicine
Tonegawa-Kuji R, Kanaoka K, Takemoto S et al. · 2026 · Brazilian journal of cardiovascular surgery
Surgical left atrial appendage occlusion (S-LAAO) is increasingly performed during cardiac surgery, but perioperative outcomes remain uncertain. Using a nationwide Japanese inpatient database, we analyzed 25,059 adults undergoing valve or…
View details →DOI: 10.21470/1678-9741-2025-0299 Negative / Null Result ReportMedicine
Gong W, Chen X, Zhao W et al. · 2026 · Sleep medicine
Background Obstructive sleep apnea (OSA) and age are strongly associated with recurrent events following acute coronary syndrome (ACS), but their interaction is unclear. This study was designed to evaluate the age-dependent impact of OSA…
View details →DOI: 10.1016/j.sleep.2026.108829 Negative / Null Result ReportMedicine
Wong ES, Taylor LL, Rojas J et al. · 2026 · Healthcare (Amsterdam, Netherlands)
Background In the Veterans Health Administration (VHA), primary care is delivered through a team-based medical home called the Patient Aligned Care Team (PACT). Increasing team panel size is one approach to addressing staffing challenges…
View details →DOI: 10.1016/j.hjdsi.2026.100778 Negative / Null Result ReportMedicine
Soares EMKVK, da Cruz CJG, Ives SJ et al. · 2026 · Nutrients
Objectives : To determine whether caffeine supplementation and its expectancy influence muscle strength (ST) and muscle endurance (ME) using a balanced-placebo design. Methods: Using a randomized, double-blind, balanced-placebo design,…
View details →DOI: 10.3390/nu18050801 Negative / Null Result ReportMedicine
Yang HS, Atkins LT, James CR · 2026 · Journal of applied biomechanics
Gait symmetry is often assumed in healthy individuals, yet functional asymmetries arise from biomechanical and neurophysiological factors. Although light upper body loading can improve walking performance, its effect on lower limb joint…
View details →DOI: 10.1123/jab.2025-0159 Negative / Null Result ReportMedicine
Karataş ŞN, Çağan E, Demirören K et al. · 2025 · Turkish archives of pediatrics
Objective Increased intestinal permeability is associated with the development of allergic and autoinflammatory diseases. Zonulin is a key physiological regulator of tight junctions in the intestinal epithelium. Thymus-expressed chemokine…
View details →DOI: 10.5152/turkarchpediatr.2025.25292 Negative / Null Result ReportMedicine
Kerlin MP, Harhay MO, Li F et al. · 2026 · Implementation science : IS
Background "Nudges" embedded in the electronic health record (EHR) facilitate desired decisions while preserving autonomy and may provide a scalable strategy to overcome the common implementation barrier of lack of knowledge about a best…
View details →DOI: 10.1186/s13012-026-01500-8 Replication FailureMedicine
Zhang B, Shi H, Cai W et al. · 2026 · International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
Objective To investigate the association between maternal hypertensive disorders of pregnancy (HDP) and childhood neurodevelopmental disorders (NDD) by Mendelian randomization (MR). Methods A two-sample MR analysis was conducted to…
View details →DOI: 10.1002/ijgo.70724 Negative / Null Result ReportMedicine
Kloosterman R, Dinh T, Michaeli J · 2026 · Journal of assisted reproduction and genetics
Purpose The purpose of this study is to assess whether discontinuing routine serum hormone testing following gonadotropin-releasing hormone (GnRH) agonist trigger affects the incidence of empty follicle syndrome (EFS) and embryological…
View details →DOI: 10.1007/s10815-025-03776-z Negative / Null Result Report
Müller A, Luckhardt C, Freitag C et al. · 2025 · Preprint
Abstract Sensory symptoms are common in autism and may result from differences in sensory processing. The locus coeruleus-norepinephrine (LC-NE) system modulates sensory processing by increasing selectivity to salience. To specify this…
View details →DOI: 10.21203/rs.3.rs-6920436/v1 Negative / Null Result Report
Quesada CR, Batson C, Holaskova I et al. · 2025 · Preprint
Abstract High tunnels can use insect exclusion screens as a mechanical pest control method within integrated pest management (IPM) programs. The impact of insect screens was evaluated on several tomato pests in commercial high tunnels. The…
View details →DOI: 10.21203/rs.3.rs-7614865/v1 Negative / Null Result ReportMedicine
Tsai PH, Hsieh CI, Kuo YC et al. · 2026 · Journal of the National Comprehensive Cancer Network : JNCCN
Background The safety of immune checkpoint inhibitors (ICIs) in patients with cancer and preexisting or acquired autoimmune rheumatic diseases (ARDs) remains unclear. This study aimed to evaluate the safety of ICIs in patients with cancer…
View details →DOI: 10.6004/jnccn.2025.7106 Negative / Null Result ReportMedicine
Litvina EA, Illarionova AR, Potapova OM · 2026 · Vestnik oftalmologii
The combination of age-related cataract and neovascular age-related macular degeneration (nAMD) presents a clinically challenging scenario, as it requires continuation of anti-angiogenic therapy during the perioperative period. The impact…
View details →DOI: 10.17116/oftalma202614202157 Negative / Null Result Report
Gil CB, Paz D, Pinales BE et al. · 2025 · Preprint
Mutations in the transcriptional cofactor HCFC1 cause methylmalonic aciduria and homocystinemia, cblX type ( cblX ) (MIM#309541), non-syndromic X-linked intellectual disability (XLID), and focal epilepsy. Zebrafish studies have revealed…
View details →DOI: 10.1101/2025.11.14.688058 Negative / Null Result ReportMedicine
Hochstenbach LMJ, Verbeek JGE, Brokken-Peters MBJ et al. · 2026 · Rheumatology (Oxford, England)
Objectives To evaluate MyRA, a web-based self-monitoring application for RA, on patient empowerment, usability and perceived usefulness. Methods MyRA was co-developed with patients and used at their own discretion during a 4-month…
View details →DOI: 10.1093/rheumatology/keaf565 Negative / Null Result ReportOpen accessMedicine
Song M, Mao M, Zhao H et al. · 2025 · Infectious agents and cancer
Objective To investigate the oncogenic risks of distinct high-risk human papillomavirus (HR-HPV) genotypes and whether multiple infections exacerbate pathogenicity, with analysis of age stratification and viral load impact. Methods…
View details →DOI: 10.1186/s13027-025-00709-4 Negative / Null Result ReportMedicine
Yamano Y, Shimizu Y, Inata Y et al. · 2026 · Clinical nutrition ESPEN
Background & aims Lipid emulsions are key components of parenteral nutrition (PN); however, concerns persist that soybean oil-based lipid emulsions may increase the risk of infection and catheter occlusion. In pediatric intensive care…
View details →DOI: 10.1016/j.clnesp.2026.102907 Negative / Null Result ReportMedicine
Matsumura M, Yasuda A, Murakami M et al. · 2025 · Biochemical genetics
Hepcidin centrally regulates systemic iron status. We previously revealed that activities of trans-factor to induce hepcidin expression are distinct between cattle and humans/mice in which regulation of hepcidin expression is…
View details →DOI: 10.1007/s10528-025-11273-2 Negative / Null Result ReportMedicine
Ruiz-Palacios GM, Cahn PE, Halperin SA et al. · 2026 · Vaccine
Background There is a concern about the potential increased risk of acquiring HIV infection after vaccination with adenovirus type 5 (Ad5) vector-based vaccines. We aimed to investigate whether Ad5-nCoV increases the risk of HIV infection.…
View details →DOI: 10.1016/j.vaccine.2026.128378 Negative / Null Result Report
Al-Mansor AN, Alhamd AD, Al-Musawi FM · 2025 · Preprint
Abstract Date palms (Phoenix dactylifera L.) struggle in arid places due to water scarcity and rising demand. Therefore, we must find more efficient ways to water them to maintain economically viable water use. Researchers in the southern…
View details →DOI: 10.21203/rs.3.rs-8022331/v1 Negative / Null Result ReportMedicine
Li RQ, Su S, Zhan LP et al. · 2026 · Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology
Objective: To investigate the differences in the changes of periodontal ligament area (PDLA) and related clinical indicators before and after maxillary central incisor movement under different orthodontic treatment regimens. Methods: This…
View details →DOI: 10.3760/cma.j.cn112144-20250722-00280 Negative / Null Result ReportMedicine
Zhang XR, Yang GJ, Jiang LC et al. · 2026 · The New phytologist
Nitrogen (N) inputs generally benefit grassland biomass production. Supporting evidence, however, comes mainly from experiments with high N input rates and from grasslands without utilization. Using a 10-yr field experiment in temperate…
View details →DOI: 10.1111/nph.70905 Negative / Null Result ReportMedicine
Liang XS, Ning Y, Wang HY et al. · 2026 · The New phytologist
Nitrogen (N) enrichment is expected to exacerbate plant phosphorus (P) limitation, yet this assumption has seldom been empirically tested. We investigated the effects of 7-9 yr of N and P addition on grassland aboveground net primary…
View details →DOI: 10.1111/nph.70893 Negative / Null Result ReportMedicine
Schaefer N, Kelaher BP, Bishop MJ · 2026 · Marine environmental research
Climate warming is exposing intertidal species to increasing temperatures, threatening the survival of those already experiencing conditions close to their upper thermal limit. On intertidal rocky shores, habitat-forming seaweeds can…
View details →DOI: 10.1016/j.marenvres.2025.107742 Negative / Null Result ReportMedicine
Dupla X, Bertagni MB, Grand S · 2025 · Environmental science & technology
Enhanced rock weathering (ERW) is a CO 2 removal technology that involves spreading finely ground silicate rock on fields. The chemical weathering of this rock powder removes atmospheric CO 2 in the form of bicarbonate ions and secondary…
View details →DOI: 10.1021/acs.est.5c09820 Negative / Null Result ReportMedicine
Hernigou P, Caton J · 2025 · International orthopaedics
Purpose Calcium pyrophosphate dihydrate (CPPD) deposition, often visible radiographically as chondrocalcinosis, frequently accompanies knee osteoarthritis and is usually encountered at the time of arthroplasty. Whether its presence…
View details →DOI: 10.1007/s00264-025-06663-5 Negative / Null Result ReportMedicine
Grummon AH, Zeitlin AB, Lee CJY et al. · 2026 · American journal of preventive medicine
Introduction As of 2025, 9 states have adopted Universal Free School Meal programs. The success of these programs depends in part on high participation. This study tested whether a social media campaign promoting school meal participation…
View details →DOI: 10.1016/j.amepre.2025.108232 Failed Experiment ReportOpen accessMedicine
McLachlan SA, Hall I, Collins A et al. · 2026 · Psycho-oncology
Background Circulating tumor DNA (ctDNA) is a novel prognostic biomarker indicating minimal residual disease and high recurrence risk. In three randomised DYNAMIC trials, ctDNA was used to guide adjuvant chemotherapy (ACT) for early-stage…
View details →DOI: 10.1002/pon.70464 