e-ISSN: Pending
Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21707 results · page 272 of 724

Negative / Null Result ReportMedicine

The Efficacy of Local Treatment for Recurrent Endometrial Cancer.

Igasaki M, Furusawa A, Kunishi M et al. · 2026 · The journal of obstetrics and gynaecology research

Aim This study aimed to evaluate the efficacy of local treatment in patients with sporadic recurrent endometrial cancer. Methods We retrospectively reviewed patients who received treatment for first recurrence of endometrial cancer at our…

View details →DOI: 10.1111/jog.70354
Negative / Null Result ReportMedicine

Hip Fracture Risk Following Lumbar Fusion: A Retrospective Cohort Study of Construct Length and Age-Stratified Outcomes.

Anundson J, Lee L, Bae S et al. · 2026 · European journal of orthopaedic surgery & traumatology : orthopedie traumatologie

Introduction Lumbar fusion alters spinal biomechanics and may increase hip loading, especially with long-segment constructs. We used a large administrative database to evaluate hip fracture risk after lumbar fusion and assess whether…

View details →DOI: 10.1007/s00590-026-04791-1
Negative / Null Result ReportMedicine

Effectiveness of a standardized patient simulation training programme on nursing students' skill in dementia screening in Malawi: A quasi-experimental study.

Chiona BC, Mbakaya BC, Liu MF · 2026 · Nurse education in practice

Aim To evaluate the effectiveness of Standardized Patient Simulation (SPS) compared with lecture-based teaching in improving dementia knowledge, dementia screening skills and mild cognitive impairment (MCI) classification accuracy among…

View details →DOI: 10.1016/j.nepr.2026.104884
Negative / Null Result ReportMedicine

Marginal Bone Loss Around Bone-Level Fully Guided Implants With Direct Implant Connection Versus Intermediate Abutment: A Randomized Clinical Trial.

Gargallo-Albiol J, Zilleruelo-Pozo MJ, Treserra-Parra A et al. · 2026 · Clinical oral implants research

Objective To determine the influence of an intermediate prosthetic abutment on peri-implant marginal bone loss (MBL) around two implant-supported fixed restorations in the posterior area. Material and methods This study included patients…

View details →DOI: 10.1111/clr.70141
Failed Experiment ReportMedicine

Retrospective assessment of low-dose and low-contrast agent protocols for photon-counting CT angiography of the aorta.

Hennes JL, Krompaß K, Huflage H et al. · 2026 · The international journal of cardiovascular imaging

Our objective was to assess dedicated low-dose (LD) and low-contrast (LC) scan protocols for aortic angiography, compared to standard protocols in photon-counting CT (PCD-CT) and energy-integrating CT (EID-CT). 57 patients (23 women) who…

View details →DOI: 10.1007/s10554-026-03757-y
Negative / Null Result ReportMedicine

Marginal and internal fit and fracture resistance of lithium disilicate laminate veneers for teeth with proximal cavities: an in-vitro comparative study.

Taş MO, Güleryüz A · 2026 · BMC oral health

Background The management of proximal cavities under porcelain laminate veneers remains a clinical challenge. Conventional strategies-such as placing an intermediate composite restoration or extending the preparation-require additional…

View details →DOI: 10.1186/s12903-026-08841-2
Negative / Null Result ReportMedicine

Comparison of visual performance among three higher-order aspheric enhanced monofocal intraocular lenses and a standard aspheric monofocal lens.

Hayashi S, Yoshida M, Hayashi K et al. · 2025 · Journal of cataract and refractive surgery

Purpose To compare visual performance among 3 types of higher-order aspheric enhanced monofocal intraocular lenses (IOLs) and a standard aspheric monofocal IOL. Setting Hayashi Eye Hospital, Fukuoka, Japan. Design Randomized comparative…

View details →DOI: 10.1097/j.jcrs.0000000000001734
Negative / Null Result ReportMedicine

Comparative outcomes of Mini-PCNL and suction-assisted flexible ureteroscopy in patients with renal stones ≥2 cm.

Durak HM, Sancı A, Hepşen E et al. · 2026 · Actas urologicas espanolas

Introduction To compare the efficacy and perioperative outcomes of miniaturized percutaneous nephrolithotomy (mini-PCNL) and flexible ureteroscopy with flexible and navigable suction ureteral access sheath (FANS-UAS) in the management of…

View details →DOI: 10.1016/j.acuroe.2026.501997
Negative / Null Result ReportMedicine

Sleep and emotional memory of preschool children adopted from foster care: a comparison with a community sample.

Rusin K, Myers A, Rech ME et al. · 2026 · Journal of pediatric psychology

Objective Children who spend time in foster care are at risk for adverse developmental outcomes, including sleep problems. Yet, research examining sleep and emotional memory has primarily focused on children with no history of foster care…

View details →DOI: 10.1093/jpepsy/jsag039
Negative / Null Result Report

Increasing clinical utility of prenatal exome sequencing: the potential power of phenotype-driven Artificial Intelligence analysis

Suerink M, Hoffer M, Dingemans A et al. · 2026 · Preprint

Abstract Prenatal exome sequencing (pES) is challenging due to rapid turnaround requirements and limited phenotype information. Analysis strategies span gene panels through exome-wide review, with Artificial Intelligence (AI) as optional…

View details →DOI: 10.21203/rs.3.rs-9634215/v1
Negative / Null Result ReportMedicine

Day-case versus conventional inpatient artificial urinary sphincter implantation: A single-center comparative study of 177 patients.

Youssef MW, Perrin L, Denormandie AC et al. · 2026 · The French journal of urology

Purpose Ambulatory artificial urinary sphincter (AUS) implantation has been proposed as an alternative to conventional inpatient surgery, but comparative data remain limited. We aimed to compare early postoperative outcomes between…

View details →DOI: 10.1016/j.fjurol.2026.103135
Negative / Null Result ReportMedicine

The benefit of robotic gastrectomy in minimally invasive surgery for elderly patients: a propensity score-matched analysis.

Jinushi K, Saito T, Fujikawa K et al. · 2026 · Surgery today

Purposes Robotic gastrectomy (RG) offers superior dexterity and visualization compared with laparoscopic gastrectomy (LG). However, its high cost requires careful patient selection. This study aimed to evaluate whether these advantages…

View details →DOI: 10.1007/s00595-026-03292-2
Negative / Null Result ReportMedicine

Antioxidant, Redox, and Immunomodulatory Effects of <i>Hypericum perforatum</i> in the <i>Galleria mellonella</i>: A 3R-Oriented Invertebrate Model.

Battal F, Kaya S, Kiraz HA · 2026 · Biomedicines

Background/Objectives : Hypericum perforatum L. (St. John's Wort) is extensively utilized in ethnopharmacology due to its anti-inflammatory and immunomodulatory properties. However, its effects on the interaction between innate immunity…

View details →DOI: 10.3390/biomedicines14061297
Replication Failure

Exploring Factors That Influence Green Space Engagement in Florida

Suhendy CCV, Koeser AK, Klein RW et al. · 2026 · Preprint

Urban parks are widely recognized for their mental health benefits, especially among frequent visitors. However, the factors underlying regular park use among older urban residents remain poorly understood. This study examined park…

View details →DOI: 10.20944/preprints202606.1589.v1
Negative / Null Result ReportMedicine

Evaluating junior medical staff confidence in assessment and management of mental health presentations in an Australian paediatric emergency department.

Daoud J, Greenwood J, Botha T et al. · 2026 · Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists

ObjectiveTo evaluate confidence levels of junior doctors working in the paediatric emergency department (ED) in the assessment and management of acute mental health presentations.MethodsThis cross-sectional study invited 89 eligible junior…

View details →DOI: 10.1177/10398562261424122
Negative / Null Result ReportMedicine

Artificial Intelligence Applications Versus Manual Methods For Literature Retrieval: A Comparative Analysis.

O'Rourke J, Byrne M, Schroers G · 2026 · Western journal of nursing research

Background Artificial intelligence (AI), particularly generative and large language models, is being used in nursing education, practice, and scholarly writing. Generative AI applications have been specifically examined for their use in…

View details →DOI: 10.1177/01939459261451723
Negative / Null Result ReportMedicine

Retrospective study on diagnostic yield and medical impact of diagnostic imaging in dogs with immune-mediated haemolytic anaemia in Belgium.

Vlassenbroek R, Peeters D, Matthewman L et al. · 2026 · The Journal of small animal practice

Objectives To assess the incidence of associative immune-mediated haemolytic anaemia in dogs diagnosed with immune-mediated haemolytic anaemia and to evaluate whether performing diagnostic imaging, specifically thoracic radiographs and…

View details →DOI: 10.1111/jsap.70159
Negative / Null Result ReportMedicine

Stabilizing Segmental Le Fort I Osteotomy Using Clear Thermoplastic Retainers Versus Arch Bars With Occlusal Splints: A Retrospective Analysis.

Wu L, Xu X, Liu X et al. · 2026 · The Journal of craniofacial surgery

In patients receiving segmental Le Fort I osteotomy as part of a clear aligner treatment regimen, this study aimed to compare the clinical effectiveness of clear thermoplastic retainers as a postoperative stabilization technique and…

View details →DOI: 10.1097/scs.0000000000012825
Negative / Null Result ReportMedicine

Midterm Clinical and Echocardiographic Outcomes After Transcatheter Aortic Valve Replacement in Patients With Severe Bicuspid Aortic Valve Stenosis.

Nienaber S, Krabichler K, Fahlbusch D et al. · 2026 · Journal of the American Heart Association

Background Outcomes >2 years after transcatheter aortic valve replacement (TAVR) for bicuspid aortic valves (BAV) are scarce, and differences between balloon-expandable transcatheter heart valves (THVs) and self-expandable (SE-THVs) are…

View details →DOI: 10.1161/jaha.125.047634