Negative / Null Result ReportMedicine
Wang N, Xu T, Li H et al. · 2026 · International journal of radiation oncology, biology, physics
Purpose To characterize the long-term endoscopic natural history of chronic radiation proctitis (CRP) and identify predictors of severe lesions in patients with locally advanced rectal cancer from the STELLAR study (NCT02533271) . Methods…
View details →DOI: 10.1016/j.ijrobp.2026.05.004 Negative / Null Result Report
Berends E, Guimbal S, Zhang X et al. · 2026 · Preprint
Background Methylglyoxal (MGO), a highly reactive by-product of glycolysis, has been associated with cognitive decline and Alzheimer’s disease, though the mechanistic role of MGO remains unclear. Moreover, conflicting findings exist…
View details →DOI: 10.64898/2026.02.20.706964 Negative / Null Result ReportMedicine
Sano Y, Yagi N, Ito Y et al. · 2026 · Digestive diseases and sciences
Background and aims The role of 5-aminosalicylates (5-ASA) in maintaining remission in patients with ulcerative colitis (UC) receiving advanced therapy remains controversial. This study evaluated the safety and feasibility of 5-ASA…
View details →DOI: 10.1007/s10620-026-09778-w Negative / Null Result ReportMedicine
Smith DC, Gemkow JW, Shiferaw BA et al. · 2026 · Journal of midwifery & women's health
Introduction Use of labor induction has increased rapidly for medical and nonmedical reasons, raising questions about its impact on cesarean birth rates. With growing incidence of elective induction of labor (IOL) at 39 weeks, uncertainty…
View details →DOI: 10.1111/jmwh.70109 Negative / Null Result ReportMedicine
Koskinen JP, Harju M, Välimäki J · 2026 · Acta ophthalmologica
Purpose To evaluate changes in corneal tomography, pachymetry and endothelial cell density (ECD) following Paul Glaucoma Implant (PGI) surgery. Methods Seventy-three patients were prospectively examined. Repeated measures anova was used to…
View details →DOI: 10.1111/aos.70063 Negative / Null Result ReportMedicine
Wang Q, Kimura Y, Oba J et al. · 2026 · European journal of pediatrics
Routine echocardiography at one month after diagnosis is the current standard for screening coronary artery abnormalities (CAA), a major complication of Kawasaki disease. The study aimed to develop and validate models to predict CAA and…
View details →DOI: 10.1007/s00431-026-06884-9 Negative / Null Result Report
Kralj-Fišer S, Čelik T, Fišer C et al. · 2026 · Preprint
Abstract Fecundity selection is widely invoked to explain female-biased sexual size-dimorphism (SSD), yet tests based on lifetime reproductive output remain scarce. We quantified lifetime fecundity and age-dependent reproduction in the…
View details →DOI: 10.21203/rs.3.rs-8436857/v1 Negative / Null Result ReportMedicine
Jenkins TL, Darden K, Pourdeyhimi B et al. · 2026 · Journal of biomechanics
Synthetic polymer scaffolds with aligned fibers permit engineered tendon development and the formation of an aligned, collagen rich matrix. However, many tissue engineered constructs cannot withstand physiologically relevant loads. Both…
View details →DOI: 10.1016/j.jbiomech.2026.113248 Negative / Null Result ReportMedicine
Mohammadi S, Cunnane ME, Juliano AF et al. · 2026 · AJNR. American journal of neuroradiology
Background and purpose Four-dimensional CT (4D-CT) is a key imaging modality for preoperative localization of parathyroid adenomas in primary hyperparathyroidism. Ultrasound (US) is frequently added with the assumption that it enhances…
View details →DOI: 10.3174/ajnr.a9306 Negative / Null Result ReportMedicine
Santoro SL, Alvarado C, Tseng SY et al. · 2026 · Journal of perinatology : official journal of the California Perinatal Association
Objective In 2022, the U.S. Supreme Court decision on Dobbs v. Jackson Women's Health Organization changed abortion access. We evaluated birth rates of Down syndrome (DS) before and after the Dobbs decision hypothesizing similarity to…
View details →DOI: 10.1038/s41372-026-02560-w Negative / Null Result ReportMedicine
Ukita K, Egami Y, Sugino A et al. · 2026 · Clinical research in cardiology : official journal of the German Cardiac Society
Background Several studies have investigated the efficacy of additional left atrial (LA) roof ablation to pulmonary vein isolation (PVI) using cryoballoon for persistent atrial fibrillation (AF). However, the evidence from randomized…
View details →DOI: 10.1007/s00392-026-02879-6 Negative / Null Result ReportMedicine
Aragón-Sánchez J, Víquez-Molina G, Aragón-Hernández J et al. · 2026 · Advances in skin & wound care
Objective The authors hypothesized that prior antibiotic treatment does not reduce culture positivity and that empirical antibiotic therapy in culture-negative cases does not increase the risk of amputation or recurrence in…
View details →DOI: 10.1097/asw.0000000000000425 Negative / Null Result ReportOpen accessMedicine
Woyke S, Troppmair T, Mair N et al. · 2026 · Journal of the International Society of Sports Nutrition
Background With increasing altitude, the partial pressure of oxygen and oxygen saturation (SpO 2 ) decrease, reducing physical performance. This study investigates whether the nutritional supplement Sanopal® (5-hydroxymethyl-2-furfural and…
View details →DOI: 10.1080/15502783.2026.2643684 Negative / Null Result ReportMedicine
García-Rudolph A, Hernández-Pena E, Del Cacho N et al. · 2026 · Revista espanola de enfermedades digestivas
Introduction and aim although generative language models have been extensively studied in the field of digestive diseases, further progress requires addressing underexplored aspects such as linguistic bias, the evaluation of clinical…
View details →DOI: 10.17235/reed.2025.11369/2025 Negative / Null Result ReportOpen accessMedicine
Mehdizadeh M, Smith JE, Gill J et al. · 2026 · Plastic and reconstructive surgery. Global open
Background Tranexamic acid (TXA) is commonly used to reduce intraoperative bleeding and complications across surgical specialties. In rhinoplasty, prior studies indicate that TXA may reduce postoperative edema and ecchymosis, but its…
View details →DOI: 10.1097/gox.0000000000007659 Negative / Null Result Report
Thorsen JS, Bononad-Olmo A, Toft AM et al. · 2026 · Preprint
ABSTRACT Today’s canola quality rapeseed press cake (RPC) is a protein-rich co-product with potential as human food, but its application is limited due to antinutritional compounds and bitter taste. It remains, however, unknown how…
View details →DOI: 10.64898/2026.03.20.712648 Negative / Null Result ReportMedicine
Teixeira PD, Casagrande DR, Rodrigues AC et al. · 2026 · Meat science
Sixteen Nellore and Sixteen Nellore × Angus steers with an initial body weight of 353 kg ±25.3 kg were randomly assigned into 2 feeding groups: whole shelled corn without forage (WSC) or WSC with sugarcane bagasse (WSCB), to evaluate…
View details →DOI: 10.1016/j.meatsci.2026.110078 Negative / Null Result ReportMedicine
Wu X, Chai Q, He J · 2026 · Developmental science
Role ethics suggests that moral obligations arise from the duties associated with one's social roles. Yet, the influence of social roles on children's moral behavior remains unclear. This research addressed this gap by testing whether…
View details →DOI: 10.1111/desc.70140 Negative / Null Result ReportMedicine
Le Baron M, David G, Ward BA et al. · 2026 · Journal of orthopaedic trauma
Objectives To evaluate whether the use of intraoperative 3D fluoroscopy during acetabular fracture fixation reduces the rate of unplanned returns to the operating room and improves radiographic quality of reduction without increasing…
View details →DOI: 10.1097/bot.0000000000003100 Negative / Null Result ReportMedicine
Bonnot C, Morin E, Da Silva Machado E et al. · 2026 · Plant physiology
Plant small secreted peptides (SSPs) are involved in numerous developmental processes and adaptive plant responses. These include root development, immunity, and symbiotic relationships in herbaceous plants; three processes crucial for…
View details →DOI: 10.1093/plphys/kiag071 Negative / Null Result ReportMedicine
Brearley FQ · 2026 · American journal of botany
Premise A number of ecologically important tropical trees form symbiotic ectomycorrhizal (EcM) fungal associations including the Dipterocarpaceae, that dominate lowland forests of South-east Asia. Whilst numerous pot-based studies have…
View details →DOI: 10.1002/ajb2.70155 Negative / Null Result ReportMedicine
Tanaka S, Kikukawa H, Nakai H et al. · 2026 · Journal of bioscience and bioengineering
Molecular weight of polyhydroxyalkanoate (PHA) is a critical factor governing their physical properties, particularly mechanical strength. It is empirically known that molecular weight of PHA varies depending on factors such as the…
View details →DOI: 10.1016/j.jbiosc.2026.01.008 Negative / Null Result ReportMedicine
Baek JY, Yu JI, Lee KW et al. · 2026 · Practical radiation oncology
Purpose The role of preoperative radiation therapy (RT) in retroperitoneal sarcoma (RPS) remains controversial across histologic subtypes. Conventional fractionated RT (ConvRT) is the current standard, but hypofractionated RT (HypoRT) is…
View details →DOI: 10.1016/j.prro.2026.02.008 Negative / Null Result ReportMedicine
Khan MM, Garcia J, Mustamand M et al. · 2026 · Children (Basel, Switzerland)
Background: Effective dental isolation is crucial for successful restorative procedures in pediatric patients; however, its potential impact on patient stress remains underexplored. This investigation comprised two independent pilot…
View details →DOI: 10.3390/children13020233 Negative / Null Result ReportMedicine
Mehta S, Huey SL, Ghugre PS et al. · 2026 · Clinical nutrition (Edinburgh, Scotland)
Background and aims Biofortification of staple crops with higher concentrations of micronutrients via traditional breeding methods is a sustainable strategy and can possibly complement fortification and other interventions to target…
View details →DOI: 10.1016/j.clnu.2025.11.002 Negative / Null Result ReportMedicine
Teramoto N, Kobayashi N, Mitsui K et al. · 2026 · The Journal of reproduction and development
Advanced paternal age affects embryonic development and offspring phenotypes. We previously demonstrated that resveratrol prevents age-associated declines in the mitochondrial DNA copy number (mt-cn) and telomere length (TL) in embryos.…
View details →DOI: 10.1262/jrd.2026-038 Negative / Null Result ReportMedicine
Carrapiso AI, Sánchez-Ordóñez M, Delgado-Adámez J et al. · 2026 · Food science and technology international = Ciencia y tecnologia de los alimentos internacional
The purpose of this study was to investigate for the first time the effect of the enrichment in white or red grape pomace stabilized by high hydrostatic pressure on the characteristics of dry-cured sausages containing additives (75 mg kg…
View details →DOI: 10.1177/10820132261461428 Negative / Null Result ReportMedicine
Hudec J, Prokopova T, Hulkova M et al. · 2026 · Anesthesia and analgesia
Background Anesthetic agents or some pathophysiological conditions can affect transcranial motor evoked potentials (TcMEP) monitoring. However, the influence of depth of anesthesia on TcMEP reproducibility in youth remains unclear due to…
View details →DOI: 10.1213/ane.0000000000008158 Negative / Null Result ReportMedicine
Sastre-Femenia MÀ, Gomis-Font MA, Fernández-Muñoz A et al. · 2026 · Antimicrobial agents and chemotherapy
The triple action of the diazabicyclooctane (DBO) zidebactam (antibacterial activity [penicillin-binding protein 2 {PBP2} inhibitor], β-lactam enhancement [synergy with PBP3 inhibitors], and β-lactamase inhibition [classes A and C])…
View details →DOI: 10.1128/aac.00346-26 Negative / Null Result ReportMedicine
Tam J, Wengler K, Yang J et al. · 2026 · Neurourology and urodynamics
Purpose Percutaneous tibial neuromodulation (PTNM) is a standard third line therapy for patients with overactive bladder (OAB). While the therapy has demonstrated efficacy, its exact mechanism of action is unclear. Functional neuroimaging…
View details →DOI: 10.1002/nau.70238