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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21283 results · page 265 of 710

Negative / Null Result ReportMedicine

The Performance of Large Language Models on Antibiotic Prophylaxis for Endodontic Treatments.

Goker Kamali S, Imamoglu YT · 2026 · Australian endodontic journal : the journal of the Australian Society of Endodontology Inc

This study compared the accuracy and repeatability of responses generated by three advanced language models (ChatGPT-4, Gemini, and DeepSeek) in determining the necessity and appropriate regimen of antibiotic prophylaxis in endodontic…

View details →DOI: 10.1111/aej.70086
Negative / Null Result ReportMedicine

Masseter microvascular perfusion after minimally invasive sagittal split ramus osteotomy: A long-term split-mouth study.

Şahin M, Asan CY, Çukurluoğlu A et al. · 2026 · Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery

Sagittal split ramus osteotomy (SSRO), a widely used mandibular procedure in orthognathic surgery, may affect the masticatory muscles through subperiosteal dissection and soft-tissue manipulation. Although minimally invasive modifications…

View details →DOI: 10.1016/j.jcms.2026.104646
Negative / Null Result ReportMedicine

Physical activity level and urinary incontinence in women after stroke: a cross-sectional study.

Doğrukök ÖN, Baser M, Özden F et al. · 2026 · Irish journal of medical science

Urinary incontinence (UI) is a common complication after stroke and negatively affects quality of life (QoL). However, the relationship between physical activity and UI in women with stroke remains unclear. To investigate the relationship…

View details →DOI: 10.1007/s11845-026-04509-6
Negative / Null Result ReportMedicine

Clinical roles and workflow characteristics of the 3D 4K exoscope in brain tumor surgery: A single-center retrospective observational study.

Ogiwara T, Sato A, Wakabayashi M et al. · 2026 · Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

Background The three-dimensional (3D) 4K exoscope has emerged as a practical visualization platform in neurosurgery, offering high-resolution imaging together with ergonomic and workflow-related advantages. The aim of this study was to…

View details →DOI: 10.1016/j.jocn.2026.112146
Negative / Null Result ReportMedicine

Transparent Film Dressing Versus Microporous Paper Tape for Temperature Probe Fixation in Preterm Neonates: A Randomized Controlled Trial.

Bhatt AH, Patel DV, Shinde MK et al. · 2026 · Indian pediatrics

Objective To compare the incidence and severity of skin damage associated with transparent film dressing and microporous paper tape used for temperature probe fixation in preterm neonates. Methods Preterm neonates requiring radiant warmer…

View details →DOI: 10.1007/s13312-026-00371-y
Negative / Null Result Report

Nocturnal Hypoxemia and Glycemic Status in Adults with Obstructive Sleep Apnea: A Retrospective Pulmonary Sleep Cohort with Positive Airway Pressure Titration Data

SAK ZHA, SUZERGOZ F · 2026 · Preprint

Abstract Background Obstructive sleep apnea (OSA) and dysglycemia frequently coexist, but pulmonary sleep risk is not always captured by the apnea-hypopnea index (AHI) alone. Because nocturnal hypoxemia may be more closely linked to…

View details →DOI: 10.21203/rs.3.rs-9674077/v1
Negative / Null Result ReportMedicine

Real-World Outcomes of Barbed Versus Interrupted Sutures for Laparoscopic Choledochotomy: A 12-Month Follow-Up in Patients With Choledocholithiasis.

Zhao P, Zhou Y, Zhang C et al. · 2026 · Surgical laparoscopy, endoscopy & percutaneous techniques

Background The optimal suture technique for primary closure after laparoscopic choledochotomy remains uncertain. We compared real-world outcomes of barbed continuous and conventional interrupted sutures in patients with…

View details →DOI: 10.1097/sle.0000000000001481
Negative / Null Result ReportMedicine

Do anaerobic bottles add value? A comparative study of blood culture bottle combinations in a tertiary care centre.

Benedict Vinothini A, Mythilipraba S, Punnen SA et al. · 2026 · Indian journal of medical microbiology

Background Bloodstream infections (BSIs) require rapid identification and susceptibility testing to guide timely antimicrobial therapy. Although paired aerobic and anaerobic blood culture bottles are routinely used, the incremental benefit…

View details →DOI: 10.1016/j.ijmmb.2026.101175
Negative / Null Result ReportMedicine

Sphincter-sparing pre-closure technique-assisted endoscopic papillectomy versus conventional endoscopic papillectomy for duodenal papilla adenomas: a multicenter retrospective cohort study.

Liu FQ, Ren LN, Zhou XR et al. · 2026 · Gastrointestinal endoscopy

Background and aims This multicenter retrospective cohort study aims to evaluate the efficacy and safety of sphincter-sparing pre-closure technique-assisted endoscopic papillectomy (EP) versus conventional EP for duodenal papilla adenomas.…

View details →DOI: 10.1016/j.gie.2026.06.038
Negative / Null Result ReportOpen accessMedicine

Perceived leg length discrepancy after total hip arthroplasty is associated with global spinopelvic coronal flexibility.

Minoji S, Ishikura H, Kudo M et al. · 2026 · Archives of orthopaedic and trauma surgery

Background Perceived leg length discrepancy (pLLD) is a common source of dissatisfaction after total hip arthroplasty (THA), even in the absence of significant radiographic discrepancies. While spinopelvic factors have been increasingly…

View details →DOI: 10.1007/s00402-026-06344-x
Negative / Null Result ReportMedicine

Assessment of insulin sensitivity and blood pepsinogen values in dairy herds with high risk for displaced abomasum.

Hirakawa-Ueno K, Makino K, Fukumori R et al. · 2026 · Research in veterinary science

This study evaluated insulin sensitivity and serum pepsinogen in dairy cows from herds with high and low risk for displaced abomasum (DA) across different lactation stages. Blood samples and body condition scores (BCS) were collected from…

View details →DOI: 10.1016/j.rvsc.2026.106278
Negative / Null Result ReportMedicine

Effects of surgical timing on inflammatory responses, oxidative stress, and immune modulation in Wagyu calves following castration.

Promsut W, Chalalai T, Saechue B et al. · 2026 · BMC veterinary research

Background Time-of-day-related physiological variation may influence immune, oxidative, and endocrine responses to surgical stress. This study evaluated the effects of morning versus afternoon surgical castration on inflammatory cytokine…

View details →DOI: 10.1186/s12917-026-05670-x
Negative / Null Result ReportOpen accessMedicine

Interfascial Plane Blocks for Perioperative Analgesia in Dogs Undergoing Laparoscopic Ovariectomy: A Retrospective Study (2020-2025).

Paolini A, Serpieri M, Bonaffini G et al. · 2026 · Animals : an open access journal from MDPI

This retrospective study compared three ultrasound-guided locoregional techniques-transversus abdominis plane (TAP), quadratus lumborum (QL), and caudal thoracic paravertebral (C-TPV) blocks-in dogs undergoing laparoscopic ovariectomy.…

View details →DOI: 10.3390/ani16111612
Negative / Null Result ReportMedicine

Determinants of Patient-Reported Experience After Interhospital Transfer Within an Integrated Health System.

Howick V JF, Lugo-Fagundo NS, Umadat G et al. · 2026 · Journal for healthcare quality : official publication of the National Association for Healthcare Quality

Objective To evaluate patient-reported experiences after interhospital transfer (IHT) within an integrated health system and identify communication and coordination domains associated with overall satisfaction. Methods This retrospective…

View details →DOI: 10.1097/jhq.0000000000000525
Negative / Null Result ReportMedicine

Microfluidic sperm selection versus density gradient centrifugation in ICSI cycles with abnormal semen parameters: a randomized sibling-oocyte study.

Thanapongpibul C, Niransuk P, Sassanarakkit S et al. · 2026 · Scientific reports

Microfluidic sperm selection (MSS) is a centrifugation-free alternative to density gradient centrifugation (DGC) for sperm preparation in intracytoplasmic sperm injection (ICSI). This prospective, randomized sibling-oocyte study included…

View details →DOI: 10.1038/s41598-026-55209-1
Negative / Null Result ReportMedicine

Association of the mitochondrial regulator PGC-1α with diabetes mellitus and myocardial ischemia-reperfusion injury in coronary artery bypass grafting.

Yildiz A, Yazici S, Yildiz Z · 2026 · BMC cardiovascular disorders

Objectives This study aimed to evaluate whether peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1α) could serve as a marker of myocardial ischemia by examining its association with cross-clamp time, which reflects…

View details →DOI: 10.1186/s12872-026-06151-7
Negative / Null Result ReportOpen accessMedicine

Low-flow oxygen delivery in patients with disturbed consciousness.

Yamada SM · 2026 · Surgical neurology international

Background When low-flow oxygen (O2) delivery is required, a nasal cannula is commonly used. However, no reports have described arterial blood gas analysis in actual patients receiving O2 simultaneously through a mask and a nasal cannula.…

View details →DOI: 10.25259/sni_1393_2025
Negative / Null Result ReportMedicine

Impact of a minimal handling care protocol on intraventricular hemorrhage in preterm infants: a retrospective cohort study.

Uygun SS, Ozturk M, Soylu H et al. · 2026 · BMC pediatrics

Background Premature birth is associated with a high risk of mortality and neurodevelopmental morbidity, with intraventricular hemorrhage (IVH) remaining a major cause of brain injury in preterm infants. Neuroprotective care bundles…

View details →DOI: 10.1186/s12887-026-07091-z
Negative / Null Result ReportMedicine

Susceptibility of sorghum to infestation by Oryzaephilus surinamensis (Coleoptera: Silvanidae) and Trogoderma variabile (Coleoptera: Dermestidae): influence of variety and temperature.

Gourgouta M, Athanassiou CG, Arthur FH et al. · 2026 · Journal of economic entomology

This study evaluated the effects of sorghum variety and temperature on the population growth, frass production, kernel damage, and weight loss caused by Oryzaephilus surinamensis (L.) and Trogoderma variabile, Ballion, two common…

View details →DOI: 10.1093/jee/toag139
Negative / Null Result Report

Perceptions of end-of-life care quality among bereaved closest contacts of community-dwelling older Australians: a cross-sectional survey of the ASPREE cohort

Keon-Cohen ZM, Tran C, Jones D et al. · 2026 · Preprint

Abstract Background High-quality end-of-life care (EOLC) is a recognised health and human-rights priority, yet Australian evidence largely derives from administrative data and cancer-specific, facility-based samples. Little is known about…

View details →DOI: 10.21203/rs.3.rs-9879018/v1
Negative / Null Result ReportOpen accessMedicine

Influence of sport mouth-formed type mouthguards on saliva secretion and composition during jaw activity: a pilot study.

van Vliet KE, Lobbezoo F, van Splunter AP et al. · 2026 · BMC oral health

BACKGROUND: We hypothesized that wearing a mouthguard may affect salivary flow and composition. Therefore, we investigated the impact of mouthguard use on saliva secretion rate and some salivary constituents under different jaw activities.…

View details →DOI: 10.1186/s12903-026-07849-y