A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21283 results · page 263 of 710
Žilytė A, Petrikaitė V · 2026 · Preprint
In this study, we evaluated the impact of different in vitro 3D culture modelling methods on the activity of doxorubicin (DOX) and 5-fluorouracil (5-FU) in human melanoma spheroids. Human melanoma A375 and IGR39 spheroids were generated…
Tomoi Y, Takahara M, Soga Y et al. · 2026 · Journal of cardiology
Background Although sodium-glucose cotransporter-2 inhibitors (SGLT2i) are recommended for patients with diabetes mellitus (DM) and peripheral artery disease (PAD), their effects on limb-related outcomes remain uncertain, and their use…
Karaca BŞ, Alşen Güney S · 2026 · Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence
This study examined the association between caregiver anxiety, ADHD symptom severity, and metacognitive awareness in children with attention-deficit/hyperactivity disorder (ADHD), and evaluated whether metacognitive awareness mediates the…
Kim HC, Park KJ · 2026 · Physical therapy in sport : official journal of the Association of Chartered Physiotherapists in Sports Medicine
Objectives To evaluate the effect of the 'Get Set-Train Smarter' warm-up program on injury incidence, type, and severity in elite Adolescent and Young Adult (AYA) Taekwondo athletes. Design Cluster-randomized controlled trial. Setting…
Xia T, Jin X, Chen D et al. · 2026 · Preprint
Sleep spindles contribute to memory consolidation, and acoustic stimulation during sleep can modulate spindle activity. However, it remains unclear whether these effects depend on the timing of stimulation relative to the spindle cycle.…
Zhao T, Dewitte L, McKenna-Plumley PE et al. · 2026 · Psychological reports
Existential isolation (EI) has been linked to depressive symptoms, yet evidence suggests it is not always distressing and can be meaningful for some individuals by satisfying their desire for uniqueness. To explore the mechanism between EI…
Tian W, Wang Y, Wang Y · 2026 · Acta psychologica
Inclusive education, extending beyond classroom access to emphasize affective support, equitable participation, and learner diversity, frames this study of university English as a foreign language (EFL) learning in the age of artificial…
Hoffmann T, Braun LR, Heske A et al. · 2026 · Preprint
Pro-environmental change necessitates discussions about the environment, yet many people avoid such conversations. We propose that this reluctance may partly stem from hypocrisy metaperceptions: because environmental issues are inherently…
Sari O, Ure UB · 2026 · JPMA. The Journal of the Pakistan Medical Association
To assess data on transfusion requirements and burdens after autologous stem cell transplantation for haematological malignancy, and to investigate the impact of transfusion requirements and burdens on patient survival outcomes. The…
Veternik M, Simera M, Martvon L et al. · 2026 · Respiratory physiology & neurobiology
Cough and expiration reflex (ER) are two fundamental airway defense mechanisms traditionally considered distinct motor behaviors. This study examined their temporal and functional interaction using an anesthetized cat model to elucidate…
Bellout H · 2026 · Investigational new drugs
A common, often unstated paradigm in T-cell engager (TCE) translation assumes that target-antigen density and drug exposure are the main efficacy drivers, with effector context secondary. This paradigm is visible in dose-escalation…
Yue J, Kim KO, Yeo YH · 2026 · Frontiers in psychology
Introduction As public services in South Korea rapidly digitalize, adults with disabilities remain at heightened risk of digital exclusion beyond access barriers. This study aims to identify joint profiles of digital attitudes and digital…
Park S · 2026 · Journal of the Air & Waste Management Association (1995)
In recent years, environmental policies aimed at reducing the use of plastic bags have received considerable attention. However, few studies have investigated whether these policies can effectively reduce vinyl waste generation over time.…
Chabbert MC, Voillequin S, Hot N et al. · 2026 · Midwifery
Objective To determine the psychological factors associated with antenatal depressive symptoms and to assess whether psychological flexibility moderates the relationship between negative anticipation and fear of childbirth and depressive…
Tayeva A, Kulazhanov T, Dikhanbayeva F et al. · 2026 · Foods (Basel, Switzerland)
Iodine deficiency remains a major nutritional concern worldwide, and fermented dairy products are considered promising vehicles for iodine fortification. However, the chemical form of iodine may influence the physicochemical and…
Hong JW, Bright T, Tucker C et al. · 2026 · JCO oncology practice
Purpose Taxanes are associated with a higher incidence of immediate hypersensitivity reactions (HSRs) compared with other classes of chemotherapeutic agents, even with premedication. This study evaluates whether a titrated infusion…
Nalla A · 2026 · Preprint
This study examined how exposure to epidemiological information about strep throat influences perceived personal risk and intended precautionary behaviors among 102 students and 26 teachers (N = 128) at a public high school in northeast…
Zheng S, Shi Y, Feng Z et al. · 2026 · Journal of wound care
Objective The efficacy of acellular dermal matrix (ADM) in immunocompromised patients' wounds has been little studied. The present study aimed to determine the wound healing effects of ADM in immunocompromised patients compared with…
Zheng H, Huang D, Liu H et al. · 2026 · Preprint
Abstract Background Cryopreservation of sperm and oocytes is increasingly used in assisted reproductive technology (ART) for infertility treatment and fertility preservation (FP). However, the impact of using autologous cryopreserved…
Olejua P, McLain AC, Ghosal R et al. · 2026 · Parkinsonism & related disorders
Introduction Postural instability and gait dysfunction (PIGD) subtype of PD has been associated with a more rapid progression of cognitive and motor dysfunction while tremor dominant (TD) subtype is associated with more severe tremors and…
Zhao J, An Y · 2026 · Preprint
Abstract Objective: This study examines how the division of household labour shapes individuals’ mental health among dual employed heterosexual couples in the United Kingdom and whether job quality conditions this association. It focuses…
Portell AL, Niec LN · 2026 · Behavior modification
Time-out from positive reinforcement (TOPR) is an effective limit-setting strategy for decreasing disruptive behaviors in young children. However, most publicly available information on TOPR (e.g., social media and other internet outlets)…
Khury F, Antonioli S, Ruff G et al. · 2026 · European journal of orthopaedic surgery & traumatology : orthopedie traumatologie
Background Testosterone replacement therapy (TRT) may cause side effects after orthopedic procedures. With total hip arthroplasty (THA) rates increasing, this study evaluates the relationship between TRT and postoperative complications in…
Prado GFA, de PB, Dias SG et al. · 2026 · EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
Background Whether the anatomical complexity of percutaneous coronary intervention (PCI) in acute coronary syndromes (ACS) influences the effects of antiplatelet therapy remains unknown. Aims We aimed to evaluate the impact of coronary…
Young TJ, Eckert TL, Burke SE · 2026 · School psychology (Washington, D.C.)
Acceptability, defined as the perception that an intervention is appropriate, fair, and reasonable, is crucial to assess during implementation (Kazdin, 1981). Despite its original conceptualization as a dynamic process, repeated…
Mechdoud S, Berton Q, Arrighi M et al. · 2026 · Archives de pediatrie : organe officiel de la Societe francaise de pediatrie
Background Few studies have examined the quality of life (QOL) of children undergoing surgery for non-syndromic craniosynostosis (NSC), with no age-specific assessment in France. Objective The CRANIOQUALITY study aimed to assess QOL across…
Jovanovic K, Jovanovic N, Dabovic L et al. · 2026 · Annals of vascular surgery
Objective To assess the predictive value of neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and systemic inflammatory response index (SIRI), for short-term morbidity and mortality in patients undergoing ruptured…
Kaya ŞM, Jobani AE · 2026 · Sensors (Basel, Switzerland)
Reliable bearing fault diagnosis in induction motors is essential for predictive maintenance and Industrial Internet of Things (IIoT) applications. However, diagnostic models that perform well under random or measurement-wise data splits…
Ates H, Korkmaz YT · 2026 · Lasers in surgery and medicine
Objectives This retrospective study evaluated the clinical outcomes associated with a photobiomodulation therapy (PBMT) protocol in patients with inferior alveolar nerve (IAN) injury following oral and maxillofacial surgery. The study…
Fiske M, DiDomenico DL, Chase HW et al. · 2026 · Bipolar disorders
Objectives Bipolar Disorder (BD)-characterized by mania, affective lability, and elevated psychosis risk-is associated with sustained attention deficits. However, evidence regarding performance on the AX-Continuous Performance test task…