e-ISSN: Pending
Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21283 results · page 262 of 710

Negative / Null Result ReportMedicine

How mathematics anxiety relates to mathematical ability in AI agent-supported instruction: the moderating role of executive function.

Lin G, Tang B, Niu Y et al. · 2026 · BMC psychology

Mathematical ability is widely recognized as a core indicator of students' cognitive development and academic achievement. However, in classroom environments where artificial intelligence (AI)-supported instruction is increasingly…

View details →DOI: 10.1186/s40359-026-04994-5
Negative / Null Result ReportMedicine

Does the Combination of Calcium Hydroxide and Chlorhexidine Gel Affect Dentinal Tubule Penetration of Epoxy Resin and Tricalcium Silicate-Based Sealers?

Baran EK, Oncu A, Celikten B · 2026 · Australian endodontic journal : the journal of the Australian Society of Endodontology Inc

This study evaluated effect of calcium hydroxide (CH) medicaments prepared with distilled water, glycerin and chlorhexidine (CHX) gel on dentinal tubule penetration of epoxy resin- and tricalcium silicate-based sealers using confocal laser…

View details →DOI: 10.1111/aej.70093
Failed Experiment ReportMedicine

Foraging crumbles reduce severe aggression in laboratory mice.

Bennett MB, Booth AB, Murdoch EQ et al. · 2026 · Physiology & behavior

Providing foraging crumbles in mouse cages is one method used in efforts to reduce aggression in laboratory mice. However, no studies have yet examined the effects of this procedure. Therefore, we investigated whether foraging crumbles…

View details →DOI: 10.1016/j.physbeh.2026.115401
Negative / Null Result Report

Analytical Discordance Between Point-of-Care Troponin Assays and a Central Laboratory High-Sensitivity Assay in a Sri Lankan Hospital Setting: Implications for Implementation

Fernando K, Fernando N, Jayasekara D et al. · 2026 · Preprint

Point-of-care testing (POCT) for cardiac troponin is increasingly used to support rapid clinical decision-making, particularly in resource-limited settings. However, while many central laboratories, including those in Sri Lanka, now use…

View details →DOI: 10.20944/preprints202605.1183.v1
Negative / Null Result ReportOpen accessMedicine

Preliminary examination of disgust learning as a potential OCD endophenotype.

Jessup SC, Zald DH, Olatunji BO · 2026 · Journal of affective disorders

Endophenotypes (intermediate phenotypes) are traits hypothesized to represent genetic risk for disorders such as OCD. However, it is unclear if disgust conditioning abnormalities may function as an OCD endophenotype. The present study…

View details →DOI: 10.1016/j.jad.2026.121619
Negative / Null Result ReportMedicine

Design and Preliminary Evaluation of a Hand-Held Surgical Robot for Enhanced Intuitive Control in Laparoscopy.

Kong K, Qiang Z, Yang Y et al. · 2026 · The international journal of medical robotics + computer assisted surgery : MRCAS

Background Surgical robots offer improved precision and stability for laparoscopy; nevertheless, their limited portability and high cost impede broader clinical applications. Methods This paper proposes a hand-held surgical robot with an…

View details →DOI: 10.1002/rcs.70176
Negative / Null Result ReportMedicine

EEG activities and connectivities associated with surtitle presentation during live opera viewing: an exploratory analysis of cognitive absorption.

Boasen J, Giroux F, Duchesneau MO et al. · 2026 · Scientific reports

Characterizing brain activities underlying text availability in an ecologically valid context and identifying whether aspects of these activities are influenced by one's state of cognitive absorption (CA) are important yet unexplored lines…

View details →DOI: 10.1038/s41598-026-56620-4
Negative / Null Result Report

Cusp Overlap Versus Standard Three-Cusp Technique for Self-Expanding Transcatheter Aortic Valves – A Single Center Experience

Ispas A, Brunet D, Saadi R et al. · 2026 · Preprint

Background: Conduction disturbances and the subsequent need for permanent pacemaker implantation (PPMI) remain a major limitation of transcatheter aortic valve replacement (TAVR) with self-expanding transcatheter heart valves (SE-THVs).…

View details →DOI: 10.20944/preprints202606.0545.v1
Negative / Null Result ReportMedicine

Effects of filtered vs. unfiltered TikTok videos on mood, body and facial satisfaction, and cosmetic surgery interest.

Harriger JA, Brown SA, Chung HG et al. · 2026 · Body image

This study investigated the effects of exposure to unfiltered vs. filtered idealized TikTok videos in a sample of 299 adult women, ages 18-83-years-old. Participants were randomly assigned to view idealized unfiltered, idealized filtered,…

View details →DOI: 10.1016/j.bodyim.2026.102030
Negative / Null Result ReportMedicine

Transdermal versus oral hormone replacement therapy and bone mass density in Turner syndrome patients: a pilot study.

Widmann K, Hager M, Windischbauer LM et al. · 2026 · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology

Objective Women with Turner syndrome (TS) are at increased risk of reduced bone mineral density (BMD) due to primary ovarian insufficiency. This study aimed to assess longitudinal changes in BMD in TS patients receiving oral or transdermal…

View details →DOI: 10.1080/09513590.2026.2692740
Negative / Null Result Report

Obesity in Chronic Obstructive Pulmonary Disease (COPD): Effects on the Inflammation, Immune System, Susceptibility to Viral Infections, and Mortality study; nature-based social services

Vitiello L, Proietti S, Limongi D et al. · 2026 · Preprint

Chronic obstructive pulmonary disease (COPD) is characterized by systemic inflammation, immune dysregulation, and increased susceptibility to infections. Obesity may influence these processes and has been proposed as a potential…

View details →DOI: 10.20944/preprints202606.1135.v1
Negative / Null Result ReportMedicine

The Effect of Binaural Sound on the Occurrence of Emergence Delirium in Children Undergoing Strabismus Surgery: A Randomized Controlled Trial.

Park JB, Lee JH, Kim YJ et al. · 2026 · Paediatric anaesthesia

Background Binaural beats, which induce brainwave entrainment, have reduced anxiety and sedative use. This study evaluated the effect of binaural beats on emergence delirium (ED) in children undergoing strabismus surgery under general…

View details →DOI: 10.1002/pan.70137
Negative / Null Result ReportMedicine

Strengths Associated With Positive Youth Development After Child Maltreatment: Application of the Resilience Portfolio Model.

Yoon S, Chang Y, Chang OD et al. · 2026 · Child maltreatment

Understanding how protective factors and strengths operate to promote positive youth development is critical for supporting youth who have experienced childhood maltreatment. Guided by the Resilience Portfolio Model, including the…

View details →DOI: 10.1177/10775595261458381
Negative / Null Result ReportMedicine

Impact of Smoking Cessation Duration on Postoperative Complications in Lung Cancer Surgery.

Çelik B, İşevi C, Pirzirenli MG et al. · 2026 · The Journal of surgical research

Introduction This study evaluated the effect of preoperative smoking cessation duration on postoperative complications after lung cancer surgery. Materials and methods In this single-center prospective cohort study, 156 patients undergoing…

View details →DOI: 10.1016/j.jss.2026.05.005
Negative / Null Result ReportMedicine

Effects of probiotics on alcohol-conditioned behaviors and hippocampal morphology in male rats.

Eraghi NG, Sefati N, Ghaffari MK et al. · 2026 · Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Alcohol Use Disorder (AUD) is a complex condition marked by physical and psychological dependence, often accompanied by lasting changes in brain regions such as the hippocampus that contribute to memory and cognitive impairments. Emerging…

View details →DOI: 10.1016/j.fct.2026.116216
Negative / Null Result ReportMedicine

A Community Located Insurance Navigation Intervention to Link Sexual and Gender Minorities in Status Neutral Care: Results From the Navigating Insurance Coverage Expansion Randomized Controlled Trial.

Umutoni V, Eavou R, Almirol E et al. · 2026 · Journal of acquired immune deficiency syndromes (1999)

Background Black and Hispanic/Latino sexual gender minorities are disproportionately affected by HIV. Structural determinants of health, such as health insurance coverage, drive care engagement and improve HIV care outcomes. Methods Black…

View details →DOI: 10.1097/qai.0000000000003788
Negative / Null Result ReportMedicine

Adverse Childhood Experiences and Maternal-Fetal Attachment: Indirect Associations via Prenatal Depressive Symptoms in a Romanian Sample.

Rusu RV, Rusu DO, Delcea C · 2026 · Behavioral sciences (Basel, Switzerland)

Adverse childhood experiences (ACEs) have been associated with increased vulnerability to depressive symptoms during pregnancy and may also be related to emerging prenatal relational processes. This cross-sectional study examined whether…

View details →DOI: 10.3390/bs16060911
Negative / Null Result ReportMedicine

Feasibility, safety and outcomes of contrast-free cardiac resynchronisation therapy device implantation: a retrospective cohort comparison.

Friedrich L, Walgenbach M, O Connor M et al. · 2026 · Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing

BACKGROUND: Left ventricular lead (LVL) implantation can be challenging in Cardiac Resynchronization Therapy (CRT). Therefore, contrast is commonly used to visualize the coronary venous system. However, contrast use is correlated with…

View details →DOI: 10.1007/s10840-026-02283-0
Negative / Null Result ReportMedicine

Sleep Quality in Later Life: How Does It Affect Driving Safety?

Barrett AE, Soulie B, Mimbs H et al. · 2026 · International journal of aging & human development

Drowsy driving is a major cause of motor vehicle injuries and fatalities, yet little is known about its impact on older adults. This group may face heightened risk due to age-related sleep issues. Using survey data from 3,411 Floridians…

View details →DOI: 10.1177/00914150261445628
Negative / Null Result ReportMedicine

Carboplatin with or without nivolumab in metastatic triple-negative breast cancer: a randomized phase II trial.

Garrido-Castro AC, Graham N, Li KX et al. · 2026 · Nature communications

This multi-institutional randomized phase II clinical trial (NCT03414684) investigated the efficacy and safety of carboplatin plus nivolumab compared to carboplatin in metastatic triple-negative breast cancer (mTNBC). The primary endpoint…

View details →DOI: 10.1038/s41467-026-73085-1