Negative / Null Result Report
Moura RA, Bisiau A, Freeman D et al. · 2025 · Preprint
Background: Perioperative fluid therapy can influence oxygen delivery and tissue oxygenation, but its effects in horses are poorly understood. Objectives: To compare two intraoperative fluid administration strategies on peripheral tissue…
View details →DOI: 10.22541/au.176131103.35539940/v1 Negative / Null Result Report
Hibner A, Tong MK, Liu L et al. · 2025 · Preprint
Abstract OBJECTIVE: To investigate single versus combination hemodynamic parameters on intraventricular hemorrhage (IVH) or mortality in preterm infants. STUDY DESIGN: Data from 482 infants under 32 weeks gestational age were analyzed,…
View details →DOI: 10.21203/rs.3.rs-7376716/v1 Negative / Null Result Report
Far ZS, Nematollahi MA, Hosseini SV et al. · 2025 · Preprint
Abstract Arthrospira platensis, commonly known as Spirulina , is an industrially cultivated cyanobacterium due to its high content of phycobiliproteins, mainly phycoerythrin, phycocyanin, and allophycocyanin. In this work, a low-cost…
View details →DOI: 10.21203/rs.3.rs-7284160/v1 Negative / Null Result ReportMedicine
Godoi Filho JRM, Abreu TFO, Vieira QR et al. · 2026 · Journal of motor behavior
We investigated the influence of mental fatigue on motor performance and learning. Additionally, we examined whether practicing under mental fatigue induces resilience in future performance under similar fatigue conditions. Ninety-two…
View details →DOI: 10.1080/00222895.2025.2585181 Negative / Null Result ReportMedicine
Liu C, Liang B, Li Z et al. · 2025 · LWT.
Adding fish oil (FO) to emulsified surimi gels enhances nutritional properties but hinders gel formation, posing a challenge to mitigate these adverse effects. In this study, sodium starch octenylsuccinate based-silver carp oil Pickering…
Replication FailureMedicine
Kroon E, Elsey JWB, Kuhns LN et al. · 2025 · Drug and alcohol dependence
Background and aims Many individuals aiming to reduce or quit cannabis use prefer self-guided interventions over formal treatment. In this pilot and feasibility randomized trial, we tested a two-week self-guided online intervention…
View details →DOI: 10.1016/j.drugalcdep.2025.112943 Negative / Null Result ReportMedicine
Randhawa S, Mukherjee T · 2025 · Journal of Food Composition and Analysis.
The research paper investigates how elemental copper and iron, affect the aging process of canola, coconut, groundnut, rice bran, soybean, and sunflower oils. Samples analysed biannually over two years indicate that the addition of copper,…
Negative / Null Result ReportMedicine
Borges CC, Alves da Silva W, de Sá Filho AS et al. · 2026 · International journal of sport nutrition and exercise metabolism
This study aimed to evaluate the effects of short-term oral L-arginine (ARG) supplementation on vascular parameters, nitric oxide (NO) concentration, and muscular performance during upper limb resistance exercise in healthy young men. A…
View details →DOI: 10.1123/ijsnem.2025-0125 Negative / Null Result Report
Fleming HA, Whines A, Whelehan P et al. · 2025 · Preprint
Central to survival is our ability to learn that the sensory properties of food are associated with metabolic interoceptive signals (e.g., changing blood glucose). These signals influence cognition and brain activity, shaping the hedonic…
View details →DOI: 10.31234/osf.io/px3ub_v1 Negative / Null Result ReportMedicine
de Alencar JN, Felicioni SP · 2025 · Journal of electrocardiology
Background Electrocardiographic (ECG) "left ventricular hypertrophy (LVH) criteria" are widely used as surrogates for increased LV mass but show limited sensitivity. We evaluated their diagnostic performance against cardiac magnetic…
View details →DOI: 10.1016/j.jelectrocard.2025.154138 Negative / Null Result ReportOpen accessMedicine
Rhee SM, Cho CH, Kim M et al. · 2025 · Clinics in shoulder and elbow
Background This study evaluates the biomechanical effects of acellular dermal matrix (ADM) patch augmentation in a rotator cuff repair model and determines the effect of medial knot tying on time-zero stability. Methods A biomechanical…
View details →DOI: 10.5397/cise.2025.00164 Negative / Null Result ReportMedicine
Meau-Petit V, Mottez C, Bhojnagarwala B et al. · 2026 · Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
Objectives Six-region lung ultrasound (LUS) scores show good predictive value for predicting surfactant need in preterm infants but rely on a fixed threshold, which may lead to misclassification near the cut-off and lack data-driven…
View details →DOI: 10.1002/jum.70092 Negative / Null Result ReportOpen accessMedicine
Sahu SA, Mishra JK, De M et al. · 2026 · GMS Interdisciplinary plastic and reconstructive surgery DGPW
Background Microvascular tissue transfer is the method of choice for oncological and trauma reconstruction. Successful free tissue transfer requires technical expertise and management of patients and surgery related factors. However,…
View details →DOI: 10.3205/iprs000194 Negative / Null Result ReportMedicine
Krackow E, Rashed J, Thompson I · 2025 · The International journal of clinical and experimental hypnosis
Steven Jay Lynn was one of the most prolific clinical psychologists who made major contributions to the scientific literature in numerous areas, including in the area of hypnosis and memory. We review this work, limited to studies…
View details →DOI: 10.1080/00207144.2025.2508410 Negative / Null Result ReportMedicine
Girgin Y, Vural GS, Yigit Y et al. · 2026 · Experimental eye research
Aim This study aimed to investigate the regenerative efficacy of topically administered insulin on corneal epithelial and stromal healing in a well-established rabbit model of ocular surface damage induced by chemical injury. Methods A…
View details →DOI: 10.1016/j.exer.2025.110775 Negative / Null Result ReportMedicine
Dao GM, Shaw CS, Betik AC et al. · 2025 · Diabetes
Despite stimulating glucagon secretion, the mechanisms by which protein ingestion lowers glucose excursions remain unclear. We investigated this using the triple stable isotope glucose tracer technique to measure postprandial glucose…
View details →DOI: 10.2337/db25-0395 Negative / Null Result ReportMedicine
Bowers AN, Tonon CC, Yeo S et al. · 2025 · Archives of oral biology
Objectives Charcoal-containing dentifrices are increasingly popular for their whitening claims, but data on antimicrobial effects are limited. This study compared the antibacterial efficacy of charcoal dentifrices versus non-charcoal…
View details →DOI: 10.1016/j.archoralbio.2025.106405 Negative / Null Result Report
Homann LA, Jahed M, Barense M · 2025 · Preprint
Retrieval practice—actively recalling information—is an established memory-strengthening technique. However, understanding how retrieval transforms memory requires examining its effects on memories that evolve across multiple episodic and…
View details →DOI: 10.31234/osf.io/923rj_v1 Negative / Null Result Report
Homann LA, Jahed M, Barense M · 2025 · Preprint
Retrieval practice—actively recalling information—is an established memory-strengthening technique. However, understanding how retrieval transforms memory requires examining its effects on memories that evolve across multiple episodic and…
View details →DOI: 10.31234/osf.io/923rj_v2 Negative / Null Result ReportMedicine
Sajjad M, Ghorbaninejad P, Bitarafan V et al. · 2026 · The Journal of nutrition
Background The amino acids, L-leucine (Leu) and L-isoleucine (Ile), and the bitter substance, quinine, reduce postprandial glucose, stimulate insulin, and/or slow gastric emptying. Whether combining these stimuli can enhance these effects…
View details →DOI: 10.1016/j.tjnut.2025.101259 Negative / Null Result Report
Fathollahzadeh I, Hashemi A, Mehan M et al. · 2025 · Preprint
Abstract The existence of empathy in rodents and, more broadly, in lower mammals has been hotly debated. Each group has designed its apparatus to address this issue. While well-established methods for measuring cooperation are in the…
View details →DOI: 10.21203/rs.3.rs-6742141/v1 Negative / Null Result ReportMedicine
Lima Neta PP, Leal PPMS, Passos VHAA et al. · 2025 · Anais da Academia Brasileira de Ciencias
Leishmaniasis is a group of diseases caused by protozoa of the genus Leishmania . Current treatments exhibit high toxicity, high costs, and parasite resistance. Consequently, the search for new drugs is of utmost importance, and drug…
View details →DOI: 10.1590/0001-3765202520250377 Negative / Null Result ReportMedicine
Chou AK, Chiu CC, Chen YW et al. · 2025 · Fundamental & clinical pharmacology
The aim of this study was to examine the effects of intrathecal lidocaine combined with guanfacine or dexmedetomidine on nociceptive and motor blockade, in comparison to clonidine. Using a rat model of intrathecal injection, we evaluated…
View details →DOI: 10.1111/fcp.70057 Negative / Null Result Report
Furukawa H, Nishikawa Y, Saito A et al. · 2025 · Preprint
Abstract This study aimed to examine the effects of visual and auditory cues on step frequency (SF) and physiological load, measured by heart rate (HR), in runners. The experiment involved two runners—a main runner and a neighboring…
View details →DOI: 10.21203/rs.3.rs-6650523/v1 Negative / Null Result Report
Chen W, Zhang C, Guo W et al. · 2025 · Preprint
Apple is an important economic species, and it always suffered by biotic stress during its growth and development. Fungi and pests are two types of biotic stress that have significant destructive effects on apples. Besides, the LRR-RLKs…
View details →DOI: 10.22541/au.175022852.28343178/v1 Negative / Null Result Report
Zhang X, Li F, Li J et al. · 2025 · Preprint
Introduction Supervised physical activity (PA) interventions have demonstrated efficacy and safety in improving health outcomes among frail populations. However, the growing disparity between limited healthcare resources and the rapidly…
View details →DOI: 10.1101/2025.06.26.25330386 Negative / Null Result ReportMedicine
Mohapatra S, Rath S, Kapoor AG et al. · 2026 · American journal of ophthalmology
Purpose To evaluate whether 0.04% mitomycin C (MMC) application at the ostium enhances the outcome of non-endoscopic endonasal dacryocystorhinostomy (NEED) in individuals with primary acquired nasolacrimal duct obstruction (PANDO). Design…
View details →DOI: 10.1016/j.ajo.2025.10.005 Negative / Null Result ReportMedicine
Al-Jada DN, Takruri HR, Talib WH et al. · 2025 · Biochemical and Biophysical Research Communications
In this study, we investigated the effectiveness of combining the ketogenic diet (KD) with high-dose vitamin C (VitC) as adjuvant nutritional therapy to mitigate doxorubicin (DOX) toxicity, with a focus on cardiotoxicity, while enhancing…
Negative / Null Result ReportMedicine
Harvin S, Guetterman TC, Hirko KA et al. · 2026 · Contemporary clinical trials
This study developed and evaluated strategies to optimize recruitment and retention to a mobile health-supported dietary intervention trial, the MyBestGI Study. This included instituting a Personal Technology Assistant and enhancing the…
View details →DOI: 10.1016/j.cct.2026.108322 Negative / Null Result Report
Lagravinese G, Castellana G, Genco M et al. · 2025 · Preprint
Abstract Background: Chronic obstructive pulmonary disease (COPD) is associated with persistent dyspnea, reduced functional capacity, and significant cognitive and affective impairments. Pulmonary rehabilitation improves the physical and…
View details →DOI: 10.21203/rs.3.rs-6974767/v1 