Negative / Null Result ReportMedicine
Kipper CW, Kis P, Burleson KN et al. · 2026 · European journal of applied physiology
Objective Exercise-induced muscle damage (EIMD) compromises neuromuscular function and reduces exercise tolerance. Whether muscle oxidative capacity (MOC), an index of mitochondrial function, is reduced by EIMD or influences neuromuscular…
View details →DOI: 10.1007/s00421-025-06073-w Negative / Null Result ReportMedicine
Valle-Cruz JA, Lopiz Y, Garríguez-Pérez D et al. · 2026 · International orthopaedics
Purpose Rotational instability is a key factor in fixation failure of extracapsular hip fractures. The U-Blade (RC) lag screw was designed to improve rotational stability. This study aimed to compare mechanical complication rates between…
View details →DOI: 10.1007/s00264-025-06714-x Negative / Null Result Report
Sujan M, Skarstad H, Rosvold G et al. · 2025 · Preprint
Objectives Gestational diabetes mellitus (GDM), particularly when combined with overweight or obesity, is associated with adverse neonatal outcomes such as high birth weight and increased adiposity. We determined the effect of a…
View details →DOI: 10.1101/2025.10.01.25337073 Negative / Null Result Report
Kim TO, Han S, Lee JB et al. · 2025 · Preprint
Background: Aspirin plus rivaroxaban reduces cardiovascular events in patients with stable atherosclerosis; however, whether Factor Xa inhibition attenuates arterial wall inflammation in humans remains unclear. Methods: We conducted a…
View details →DOI: 10.1101/2025.11.18.25340536 Negative / Null Result ReportMedicine
Athan E, Greenberg RN, Baker DA et al. · 2026 · Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Background A vaccine that prevents Staphylococcus aureus skin and soft tissue infections (SA-SSTIs) would have a major impact on public health. Methods A two-part randomized study began with a phase 1, first-in-human, dose-escalation that…
View details →DOI: 10.1093/cid/ciag162 Negative / Null Result ReportMedicine
Carvajal-Encina F, Carvajal Rojas L · 2025 · Andes pediatrica : revista Chilena de pediatria
Prematurity is a challenge due to its high morbidity and mortality. The Explicit Health Guarantees (GES) for Premature Birth Prevention, implemented in 2005, have not been evaluated. Objective To evaluate the impact of the GES on perinatal…
View details →DOI: 10.32641/andespediatr.v96i5.5799 Negative / Null Result ReportMedicine
Chung J, Park S, Park SJ et al. · 2026 · The American journal of medicine
Objective This study aimed to evaluate the conflicting effects of weight change and smoking cessation on fracture risk in male patients with newly diagnosed type 2 diabetes mellitus (T2DM). Methods Using the National Health Insurance…
View details →DOI: 10.1016/j.amjmed.2025.12.014 Negative / Null Result ReportMedicine
Paskeviciene E, Skemiene K, Pampuscenko K et al. · 2025 · Journal of pharmacological sciences
Imeglimin, a novel oral antidiabetic drug, has been suggested to affect mitochondrial functions in some types of cells and tissues, however, it has never been investigated whether aging has an impact on its pharmacological effects in the…
View details →DOI: 10.1016/j.jphs.2025.10.001 Negative / Null Result ReportMedicine
Streit A, Hoffmann M, Blesl A et al. · 2025 · Quality management in health care
Background Effective discharge planning is an important factor of hospital care and should follow a comprehensive assessment of patients at risk for adverse events during discharge. The study's aim was to analyze whether the use of the…
View details →DOI: 10.1097/qmh.0000000000000543 Negative / Null Result ReportOpen accessMedicine
Büyükbezirci G, Demiralp N, Keles S et al. · 2026 · Journal of pain research
Purpose Postherpetic neuralgia (PHN) is one of the most debilitating complications of herpes zoster and represents a major cause of chronic neuropathic pain. Increasing evidence suggests that immune dysregulation plays a critical role in…
View details →DOI: 10.2147/jpr.s611477 Negative / Null Result ReportMedicine
Shidara S, Ito S, Desai K et al. · 2026 · Bone
Skeletal stem/progenitor cells (SSPCs) play a fundamental role in maintaining skeletal homeostasis throughout life. Leptin receptor (Lepr)-positive cells were initially identified as SSPCs in the long bone marrow and later in the…
View details →DOI: 10.1016/j.bone.2026.117833 Negative / Null Result ReportOpen accessMedicine
Kim HJ, Kim N, Kim J et al. · 2025 · Scientific reports
Robot-assisted laparoscopic prostatectomy (RALP) is associated with hemodynamic shifts; patients on angiotensin receptor blockers (ARBs) are especially susceptible to intraoperative hypotension. We investigated whether induction with…
View details →DOI: 10.1038/s41598-025-23469-y Negative / Null Result ReportMedicine
Berthoud V, Nguyen M, Vinay J et al. · 2026 · Anaesthesia, critical care & pain medicine
Introduction In thoracic surgery, all respiratory muscles have a significant increase in workload, and recruitment of these muscles may be important, especially in the presence of diaphragmatic dysfunction. Evaluating diaphragmatic and…
View details →DOI: 10.1016/j.accpm.2025.101683 Negative / Null Result ReportMedicine
Bircher B, Aebischer P, Wimmer W et al. · 2026 · American journal of otolaryngology
Objective To evaluate the clinical implementation of preoperative, anatomy-tailored planning for electrode selection in cochlear implantation, quantify planning accuracy under routine conditions, and identify factors associated with…
View details →DOI: 10.1016/j.amjoto.2025.104777 Negative / Null Result ReportMedicine
Hao X, Zhang Z, Cai C et al. · 2026 · International journal of surgery (London, England)
Background Dexmedetomidine was widely used in anesthesia management during cardiac surgery. The purpose was to evaluate the safety and efficacy of intraoperative dexmedetomidine in the treatment of postoperative depression in adult…
View details →DOI: 10.1097/js9.0000000000003906 Negative / Null Result ReportMedicine
Wittberg DM, Admassu F, Aragie S et al. · 2026 · Tropical medicine & international health : TM & IH
Objectives Few randomised trials have been done to assess the impact of hygiene interventions on trachoma even though hygiene improvements feature prominently in the strategy for global elimination of trachoma. This study's aim was to…
View details →DOI: 10.1111/tmi.70086 Negative / Null Result ReportMedicine
Liu C, Deng G, Wang Y et al. · 2026 · Stroke and vascular neurology
Background Transradial access has become an increasingly preferred approach for cerebral angiography. However, embolic events, often clinically silent, remain a frequent concern. Despite routine use, the efficacy and safety of heparin…
View details →DOI: 10.1136/svn-2025-004887 Negative / Null Result ReportOpen accessMedicine
Jiang C, Zhao Z, Yang Z et al. · 2026 · Circulation
Background Observational studies have suggested that SGLT2 (sodium-glucose cotransporter 2) inhibitors are associated with a lower risk of atrial fibrillation (AF) recurrence after catheter ablation in patients with AF with concomitant…
View details →DOI: 10.1161/circulationaha.125.077447 Negative / Null Result ReportMedicine
Krzyżaniak M, Warmiński K, Olba-Zięty E et al. · 2025 · Industrial Crops & Products
Camelina sativa (L. Crantz) is an annual oilseed crop cultivated for industrial and food purposes. To expand camelina's cultivation area, improve yields, and reduce weed pressure, the crop can be grown in intercropping system. The aim of…
Negative / Null Result ReportMedicine
Perez-Valero I, Corona Mata D, Crussells Canales MJ et al. · 2026 · International journal of antimicrobial agents
Objective To evaluate if switching from dolutegravir/lamivudine (DTG/3TC) to bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) improves neuropsychiatric tolerability in suppressed adults with stable neuropsychiatric…
View details →DOI: 10.1016/j.ijantimicag.2026.107825 Negative / Null Result ReportMedicine
Zhang F, Zhong Y, Li Q et al. · 2025 · High altitude medicine & biology
Zhang, Fengying, Yang Zhong, Qiuyue Li, Doudou Hao, Zhiyou Shi, Suying Zhu, Qian Zhang, and Yunhong Wu. Does Hydrogen-Rich Water Reduce Oxidative Stress in Patients with Chronic Mountain Sickness? A Randomized, Blinded, Controlled Trial.…
View details →DOI: 10.1177/15578682251401137 Negative / Null Result ReportMedicine
Crawford AM, Striano BM, Schoenfeld AJ et al. · 2026 · Spine
Study design Retrospective multicenter cohort study. Objective To compare the safety and efficacy of venous thromboembolism prophylaxis (VTE) strategies between two high-volume spine centers with distinct protocols. Summary of background…
View details →DOI: 10.1097/brs.0000000000005607 Negative / Null Result ReportMedicine
Kinsella A, Gilligan P · 2025 · Irish medical journal
Aim Admission rate is a key performance indicator for Emergency Departments (EDs). Senior hospital management advised that, if discharge by on-call teams was possible within 24 hours, a patient should be termed 'ambulatory' and remain in…
Negative / Null Result ReportMedicine
Alves LL, Pinheiro Rosa DC, Freire ML et al. · 2025 · The Journal of antimicrobial chemotherapy
Objective This study aimed at evaluating the combination of a topical hydrophilic gel of paromomycin (PA) with intralesion meglumine antimoniate (Glu IL) or systemic administration of liposomal amphotericin B (AmphLipo) for the treatment…
View details →DOI: 10.1093/jac/dkaf362 Negative / Null Result ReportOpen accessMedicine
Warrier T, Martínez-Hoyos M, Porras De Francisco E et al. · 2026 · ACS infectious diseases
A bromoindazole was reported with the ability to rapidly and extensively kill Mycobacterium tuberculosis (Mtb) in vitro, but only in the presence of sublethal levels of reactive nitrogen species (RNS) (Warrier et al., ACS Infectious…
View details →DOI: 10.1021/acsinfecdis.5c00879 Negative / Null Result ReportMedicine
Sher DJ, Avkshtol V, Lin MH et al. · 2025 · Journal of the National Cancer Institute
Background The utility of adaptive radiotherapy (ART) for head and neck squamous cell carcinoma (HNSCC) remains poorly defined. Daily ART (DART) promises both anatomic adaptation and planning target volume (PTV) reduction. In this…
View details →DOI: 10.1093/jnci/djaf232 Negative / Null Result ReportMedicine
Furman CR, Worth IA, Zhang JD et al. · 2025 · Behavioral medicine (Washington, D.C.)
Eating and exercise habits established in adolescence are associated with immediate and long-term health outcomes. These habits may be influenced by adolescents' socioeconomic status (SES), such that low SES households often experience…
View details →DOI: 10.1080/08964289.2025.2471875 Negative / Null Result ReportOpen accessMedicine
Hay AD, Abbs S, Ridd M et al. · 2026 · JAMA internal medicine
Importance Most antibiotic prescribing takes place in primary care, driving antimicrobial resistance, a top-10 threat to global public health. There is considerable international interest in whether rapid multiplex microbiological…
View details →DOI: 10.1001/jamainternmed.2026.1426 Negative / Null Result ReportMedicine
Zhang IY, Flum DR, Khandelwal S et al. · 2025 · Annals of surgery
Objective We aimed to evaluate the impact of an electronic health record (EHR)-based default "nudge" intervention on opioid prescribing after common surgical operations. Background Given ongoing national challenges in opioid use and…
View details →DOI: 10.1097/sla.0000000000006977 Negative / Null Result Report
Le Sage V, Vu MN, Maltepes MA et al. · 2025 · Preprint
In China, low pathogenic avian influenza (LPAI) H3N8 virus is widespread among chickens and has recently caused three zoonotic infections, with the last one in 2023 being fatal. Here we evaluated the relative pandemic risk of this 2023…
View details →DOI: 10.1101/2025.10.02.679960 