Negative / Null Result ReportMedicine
Fujii N, Katagiri A, Nakagome K et al. · 2026 · Scandinavian journal of medicine & science in sports
Continuous monitoring of core temperature is crucial for optimizing exercise performance, promoting health, and ensuring safety. Here, we evaluated the validity of a machine learning-based earbud-type core temperature sensor during…
View details →DOI: 10.1111/sms.70315 Negative / Null Result Report
Lamekina Y, Panela R, Kortje C et al. · 2026 · Preprint
Event segmentation – the division of continuous experience into meaningful units – is essential for understanding narratives. Although event segmentation has been widely studied in visual contexts, little is known about how listeners…
View details →DOI: 10.31234/osf.io/x47cm_v3 Negative / Null Result Report
Lamekina Y, Panela R, Kortje C et al. · 2026 · Preprint
Event segmentation – the division of continuous experience into meaningful units – is essential for understanding narratives. Although event segmentation has been widely studied in visual contexts, little is known about how listeners…
View details →DOI: 10.31234/osf.io/x47cm_v2 Negative / Null Result Report
Selimović-Pašić A, Haglund L, Bensberg M et al. · 2026 · Preprint
The BCL-2 inhibitor venetoclax (VEN) in combination with hypomethylating agents (HMAs) has improved treatment responses in acute myeloid leukaemia (AML), but the mechanisms underlying their synergy remain unclear. We investigated the role…
View details →DOI: 10.64898/2026.04.13.718134 Failed Experiment ReportMedicine
Katanec T, Šimunović L, Likić R et al. · 2026 · Acta stomatologica Croatica
Objective Statins exhibit pleiotropic effects on bone metabolism, including osteogenic and angiogenic activity. The aim of this pilot study was to evaluate whether local application of simvastatin combined with a bovine-derived xenogeneic…
View details →DOI: 10.15644/asc60/2/6 Negative / Null Result ReportMedicine
Maksymowych WP, Weiss PF, Francavilla ML et al. · 2026 · Seminars in arthritis and rheumatism
Objective The OMERACT JAMRIS working group has defined a spectrum of MRI lesions in the sacroiliac joint (SIJ) in pediatric cases with spondyloarthritis (SpA) that match domains for inflammation and structural damage. We aimed to assess…
View details →DOI: 10.1016/j.semarthrit.2026.153018 Negative / Null Result Report
Aguiar PV, Paul BT · 2026 · Preprint
Older adults with age-related hearing loss (OAHL) are more strongly influenced by vision during audiovisual perception tasks compared to typical-hearing old adults, suggesting a greater weighting of visual input in the former group. This…
View details →DOI: 10.31234/osf.io/e9skc_v1 Failed Experiment ReportMedicine
Toshida K, Sugitani Y, Itoh S et al. · 2026 · Surgery today
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality. Machine learning (ML) may enable the noninvasive prediction of histopathological features using clinical and imaging data. This study evaluated the utility of…
View details →DOI: 10.1007/s00595-026-03317-w Negative / Null Result ReportMedicine
Brandon AS, Murphy BS, Nam Y et al. · 2026 · The American journal of cardiology
Peripheral arterial disease (PAD) has many established risk factors, but social determinants of health (SDoH) are increasingly recognized as a cardiovascular disease risk factor. The multi-ethnic study of atherosclerosis (MESA) cohort was…
View details →DOI: 10.1016/j.amjcard.2026.05.033 Negative / Null Result ReportMedicine
Arnaoutis G, Vallas G, Toubekis AG et al. · 2026 · International journal of sport nutrition and exercise metabolism
Beetroot juice (BRJ) has been proposed as an ergogenic aid due to its high nitrate content, yet evidence from field-based studies in elite swimmers remains limited. This study investigated the acute effects of concentrated BRJ ingestion on…
View details →DOI: 10.1123/ijsnem.2026-0014 Negative / Null Result ReportMedicine
Ayaz SN, Kucuk M, Yanık Nalbantoğlu D et al. · 2025 · Odontology
We evaluated the effect of supplementary instrumentation on the removal of gutta-percha and compared the efficacy of three file systems with different metallurgical properties via micro-computed tomography (micro-CT). Forty-two moderately…
View details →DOI: 10.1007/s10266-025-01260-9 Negative / Null Result ReportMedicine
Moghadam H, Sourinejad I, Kalbassi MR et al. · 2026 · Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology
Widely recognized for its translational relevance, the zebrafish (Danio rerio) is a validated model for evaluating antihyperglycemic agents. Nanocapsulation technologies have been proposed to enhance the bioefficacy of natural compounds…
View details →DOI: 10.1007/s00360-026-01668-x Negative / Null Result Report
Micca L, Albouy G, King BR et al. · 2026 · Preprint
Motor memory retention is impaired in Parkinson’s disease (PD), affecting long-term rehabilitation outcomes. It appears that NREM sleep could be beneficial for consolidation processes in PD, and could be leveraged with non-invasive sleep…
View details →DOI: 10.64898/2026.04.22.26351552 Negative / Null Result Report
Robin N, Bonnin T, Rienzo FD et al. · 2026 · Preprint
Abstract Pre-serve preparatory movements including imagery and air movements are commonly observed in tennis players during both training and competition. The present study (ACTES URp54-2025-05) compared the effects of pre-performance…
View details →DOI: 10.21203/rs.3.rs-8967123/v1 Negative / Null Result ReportMedicine
Mayer S, Wegehaupt FJ, Hamza B · 2026 · BMC oral health
Objectives This in-vitro study compared the protective effects of a 5000-ppm fluoride dentifrice with an anti-erosive 1450-ppm formulation containing stannous chloride and chitosan under erosive, abrasive, and erosive/abrasive conditions.…
View details →DOI: 10.1186/s12903-026-08546-6 Negative / Null Result Report
Chew KH, Michael MC, Ghani NRNA · 2026 · Preprint
Abstract Objectives To investigate the influence of different coronal restorative strategies on the fracture resistance and failure patterns of endodontically treated maxillary incisors following thermomechanical aging. Materials and…
View details →DOI: 10.21203/rs.3.rs-8922381/v1 Negative / Null Result Report
Gama de Matos D, de Santana JL, Aidar FJ et al. · 2025 · Preprint
Background: Frailty is a multifactorial condition that significantly impacts older adults health and independence, which can be mitigated through training. This study examined the effects of a 12-week progressive strength training (PST)…
View details →DOI: 10.20944/preprints202511.1155.v1 Negative / Null Result ReportMedicine
Yang Y, Lan C, Jiang Z · 2026 · Tissue engineering and regenerative medicine
Background This study evaluates the impact of Bacillus subtilis dual-strain enteric-coated capsules combined with vonoprazan-amoxicillin (VA) therapy on Helicobacter pylori (Hp) eradication rates, gastrointestinal symptoms, adverse events…
View details →DOI: 10.1007/s13770-026-00803-7 Negative / Null Result ReportMedicine
Pinheiro-Machado E, Kuiper T, Huurman RH et al. · 2026 · Journal of biomedical materials research. Part B, Applied biomaterials
Polymer scaffolds are a promising platform for the transplantation of insulin-producing cells in Type 1 Diabetes. While vascularization has been a primary focus due to its role in oxygen and nutrient delivery, the interplay between blood…
View details →DOI: 10.1002/jbm.b.70088 Negative / Null Result ReportMedicine
Ten Berg S, Beske RP, Grand J et al. · 2026 · European heart journal. Acute cardiovascular care
Background Noradrenaline is frequently used to increase mean arterial pressure (MAP) in patients with cardiogenic shock caused by infarction-related out-of-hospital cardiac arrest (OHCA-AMICS). This Blood pressure and Oxygenation-Targets…
View details →DOI: 10.1093/ehjacc/zuag045 Negative / Null Result ReportMedicine
Dong M, Niimi T, Maturana AD · 2026 · Journal of cellular physiology
Intracellular calcium (Ca 2+ ) signaling controls myoblast proliferation, fusion, and myofiber formation. In myoblasts, Transient Receptor Potential Canonical (TRPC) channels, with TRPC1 as a predominant isoform, mediate store-operated…
View details →DOI: 10.1002/jcp.70173 Negative / Null Result Report
Hirlemann M, Garmon M, Ribeiro-Parenti L et al. · 2026 · Preprint
ABSTRACT This study investigates the individual and combined effects of Roux-en-Y gastric bypass (RYGB), sleeve gastrectomy (SG), and metformin on glucose regulation in a non-obese, insulin-deficient model of type 2 diabetes. Female…
View details →DOI: 10.64898/2026.04.23.720381 Negative / Null Result ReportMedicine
Wongwachira C, Suwajanakorn D, Kongwattananon W et al. · 2026 · Eye (London, England)
Purpose To compare the SITA Standard 24-2 and SITA Faster 24-2 C tests in patients with chloroquine/hydroxychloroquine (CQ/HCQ) retinopathy and those at high risk. Methods A prospective, cross-sectional study of 75 participants who…
View details →DOI: 10.1038/s41433-026-04462-9 Negative / Null Result Report
Shober A, Qin Z, Pokhrel S et al. · 2026 · Preprint
Abstract Background and Aims Historical manure applications on the Delmarva Peninsula have created legacy soil phosphorus (P) accumulation, yet winter wheat ( Triticum aestivum L.) often faces early-season P deficiency due to fixation in…
View details →DOI: 10.21203/rs.3.rs-8972522/v1 Negative / Null Result ReportMedicine
Morales Ruiz S, Wang Z, Miura T et al. · 2026 · Virology
We constructed two novel LC16-derived vaccinia viruses as candidate mpox vaccines to clarify the contribution of B5 to vaccine-induced protection. LC16m8Δ2 is a B5R-null mutant derived from LC16mO that contains no artificial sequences.…
View details →DOI: 10.1016/j.virol.2026.110888 Negative / Null Result Report
Beffara B, Hadj-Bouziane F, Ben Hamed S et al. · 2026 · Preprint
The control of selective visuo-spatial attention is known to rely on multiple signals, including reward. While most attention control signals are well acknowledged to interact with each other, the case of reward has led to mixed findings…
View details →DOI: 10.31234/osf.io/zgkj8_v2 Negative / Null Result ReportMedicine
Sinha P, Chatterjee P, Kathiresan P et al. · 2026 · Journal of the American Geriatrics Society
Objective To evaluate the efficacy of adjunct probiotic supplementation (Lactobacillus helveticus and Bifidobacterium longum) alongside standard care compared to placebo in older adults with moderate unipolar depression. Methods A…
View details →DOI: 10.1111/jgs.70530 Negative / Null Result ReportMedicine
Pontet Y, Aguirrezábal P, Pintos J et al. · 2026 · Journal of clinical gastroenterology
Background In adults, the diagnosis of celiac disease (CeD) relies on the presence of disease-specific antibodies and the confirmation of duodenal atrophy. This study aimed to develop a diagnostic model to predict duodenal atrophy in…
View details →DOI: 10.1097/mcg.0000000000002315 Negative / Null Result ReportMedicine
Tanabe H, Watanabe D, Agawa M et al. · 2026 · Biochemical and biophysical research communications
Objectives Intestinal fibrosis is a severe complication of Crohn's disease (CD). While ADAMDEC1 has been identified as a marker for specific fibroblast subsets, its functional role in fibrogenesis remains unclear. This study aimed to…
View details →DOI: 10.1016/j.bbrc.2026.153749 Negative / Null Result ReportMedicine
Souza AF, Fraga MAA, Correr AB et al. · 2026 · Dental materials : official publication of the Academy of Dental Materials
Objectives To evaluate the effects of incorporating the antibacterial monomer dimethylaminohexadecyl methacrylate (DMAHDM; 2.5% and 5% wt%) and amorphous calcium phosphate nanoparticles (NACP; 2 wt%) on the antibacterial activity,…
View details →DOI: 10.1016/j.dental.2026.05.014 