Negative / Null Result ReportMedicine
Xiang H, Lin C, Chen S et al. · 2025 · Current HIV research
Introduction Peripheral blood lymphocyte subsets have been shown to influence prognosis in HIV-associated Diffuse Large B-Cell Lymphoma (HIV-DLBCL), a rare and highly aggressive form of non-Hodgkin's lymphoma linked to immunosuppression…
View details →DOI: 10.2174/011570162x369231250818043532 Negative / Null Result ReportMedicine
Bitran AM, Kleiman EM, Rizvi SL · 2026 · Archives of suicide research : official journal of the International Academy for Suicide Research
Objective Suicidal communications (SCs)-also known as suicide threats or "gestures," whereby an individual verbally or behaviorally signals suicidal intent-present a serious challenge to clinicians and loved ones, who may struggle to…
View details →DOI: 10.1080/13811118.2025.2512455 Negative / Null Result ReportOpen accessMedicine
Mehta R, Sah R · 2025 · Cerebral circulation - cognition and behavior
•SDMT drop at baseline linked to higher Fazekas (WMH) scores.•No follow-up MoCA/SDMT association after multiple correction.•Practice effects likely inflated cognitive test recovery scores.•High attrition biased against fatigue and…
View details →DOI: 10.1016/j.cccb.2025.100394 Negative / Null Result ReportMedicine
Liampas I, Tsirelis D, Dastamani M et al. · 2024 · Journal of molecular neuroscience : MN
Background and objectives Data on the association between BDNF rs6265 and multiple sclerosis (MS) are scarce and heterogeneous. Materials and methods We undertook a case-control study design. Newly diagnosed individuals with MS based on…
View details →DOI: 10.1007/s12031-024-02301-8 Negative / Null Result Report
Yin Q, Shu T, Chen Z et al. · 2025 · Preprint
Abstract Background To investigate the relationship between emotional dysregulation, as measured by the emotional go/nogo task, and the multidimensional profile of borderline personality disorder (BPD). Methods Eighty-two participants (32…
View details →DOI: 10.21203/rs.3.rs-6498296/v1 Replication Failure
Ajam G, Daryabor G, Jazi NN et al. · 2025 · Preprint
Abstract Viruses are among the most infectious agents thought to contribute to the development of autoimmune disorders. Adenoviruses, in particular, are widely utilized for various applications, including gene therapy, vaccine vectors, and…
View details →DOI: 10.21203/rs.3.rs-5938384/v1 Replication Failure
Heasley CK, Stefanova V, Funk C et al. · 2025 · Preprint
Background Bifidobacterium longum subspecies infantis ( B. infantis ) abundance in the infant gut may be associated with growth and health outcomes. However, these relationships have not been widely studied in settings where B. infantis is…
View details →DOI: 10.1101/2025.07.07.25329844 Replication FailureOpen accessMedicine
Miceli MH, Dalton LM, Pasqualotto AC et al. · 2025 · Open Forum Infectious Diseases
Background Histoplasma urine antigen detection, a valuable diagnostic tool, is often used to monitor response to antifungal therapy, but persistently positive antigen values, even when the infection has resolved, often present a clinical…
View details →DOI: 10.1093/ofid/ofaf448 Replication FailureOpen accessMedicine
Akowundu PK, Salako AO, Akinsete AM et al. · 2025 · BMC pediatrics
Background Sickle cell anaemia (SCA) is a lifelong, chronic haemolytic disorder with episodic vaso-occlusive crises (VOC) and chronic end-organ damage. Red cell dehydration during a VOC changes permeability with loss of potassium and…
View details →DOI: 10.1186/s12887-025-06079-5 Replication FailureOpen accessMedicine
Blanco JR, Albendin-Iglesias H, Negredo-Puigmal E et al. · 2025 · PloS one
Introduction Inflammation is linked to multiple health conditions. Emerging evidence suggest it may play a role in the association between social isolation - loneliness and health outcomes. People living with HIV (PLWH) exhibit chronic…
View details →DOI: 10.1371/journal.pone.0335949 Replication FailureOpen accessMedicine
Solanki JD, Shah AP, Lalwani N et al. · 2025 · Journal of family medicine and primary care
Introduction Among type 2 diabetics (T2D), macrovascular complication lower limb Peripheral Arterial Disease (PAD) and microvascular complication Diabetic Peripheral Sensory Neuropathy (DPSN) have scarcely studied concordance and their…
View details →DOI: 10.4103/jfmpc.jfmpc_1168_24 Negative / Null Result ReportMedicine
Normann SS, Andersen HR, Lund LC et al. · 2025 · Environmental research
Background Over the past decade, the use of organophosphate insecticides including chlorpyrifos has faced increasing restrictions due to health concerns, leading to a rise in use of pyrethroids. Concerns about neurodevelopmental insults…
View details →DOI: 10.1016/j.envres.2025.120853 Negative / Null Result ReportMedicine
Razeghi M, Abdoli S, Mardanian Dehkordi L · 2024 · Applied nursing research : ANR
Aim Identify the relationship between a sense of belonging and psychosocial well-being in individuals with type 1 diabetes (T1D) in Iran. Background Understanding this relationship is vital for tailored nursing interventions to enhance…
View details →DOI: 10.1016/j.apnr.2024.151843 Negative / Null Result ReportOpen accessMedicine
Gao Y, Hsu V, Kil A et al. · 2026 · The Journal of clinical endocrinology and metabolism
Context Previous animal studies show association between osteocalcin (OC) and type 2 diabetes-related quantitative traits (QTs), with some suggesting these effects being mediated by adipokines. Replication in humans has been inconsistent.…
View details →DOI: 10.1210/clinem/dgaf460 Negative / Null Result ReportMedicine
Fitzgerald M · 2024 · Trends in Food Science & Technology.
The messaging around processed food recently is that it is unhealthy and associated with the onset of chronic disease. However, food is processed for many reasons that range from preservation to safety, and then more recently in response…
Negative / Null Result ReportOpen accessMedicine
Dousset J, Curnock MI, Wang JZ et al. · 2026 · Environmental management
As the Great Barrier Reef (GBR, the Reef) faces unprecedented threats, reducing anthropogenic pressures and fostering stewardship within coastal communities are among the strategic priorities identified in the Australian and Queensland…
View details →DOI: 10.1007/s00267-026-02525-x Negative / Null Result ReportMedicine
Huh K, Kang M, Jung J · 2023 · European heart journal
Background and aims An increased risk of aortic aneurysm and aortic dissection (AA/AD) has been reported with fluoroquinolone (FQ) use. However, recent studies suggested confounding factors by indication. This study aimed to investigate…
View details →DOI: 10.1093/eurheartj/ehad627 Negative / Null Result ReportOpen accessMedicine
Hecht S, Rojas-Ruiz A, Boucher M et al. · 2025 · Lung
Introduction A recent study on BALB/c and C57BL/6 mice demonstrated a clear lack of association between the in vivo response to nebulized methacholine and the degree of airway narrowing ex vivo in a model of asthma induced by a daily…
View details →DOI: 10.1007/s00408-025-00840-4 Replication FailureOpen accessMedicine
Lin X, Ou J, Wu G et al. · 2025 · Biochemistry and biophysics reports
Introduction Venous malformations are the most common congenital vascular anomaly, accounting for 65 % of all congenital vascular abnormalities. This study aims to investigate the correlation between genetic polymorphisms of MALAT1 and the…
View details →DOI: 10.1016/j.bbrep.2025.102209 Replication Failure
Ma Y, Mayes MD, Guo X et al. · 2024 · Preprint
Abstract Objective This study aimed to examine whether a reported SSc-associated SNP rs2841277 in the PLD4 gene identified in an Asian population was also associated with SSc in US Caucasians. Methods The US Caucasian cohort consisting of…
View details →DOI: 10.21203/rs.3.rs-4238970/v1 Replication FailureOpen accessMedicine
Velaga SB, Alagorie AR, Nittala MG et al. · 2025 · Ophthalmology science
Purpose To evaluate the change in the area of reticular pseudodrusen (RPD) and choroidal thickness over 2 years in eyes with age-related macular degeneration (AMD). Design Longitudinal cohort study. Subjects The study reviewed 1332 eyes…
View details →DOI: 10.1016/j.xops.2025.100881 Replication FailureMedicine
Belica I, Blasko F, Sleziak I et al. · 2025 · Biological psychology
Resting heart rate variability (HRV) reflects rhythmic changes in heart rate over time associated with autonomic nervous system (ANS) activity. It has served as a predictor of health and the development of various diseases. Therefore, it…
View details →DOI: 10.1016/j.biopsycho.2025.109073 Negative / Null Result ReportOpen accessMedicine
Govender V, Govender K, Moodley D · 2026 · BMC infectious diseases
BACKGROUND: Maintaining viral suppression in the postpartum period is critical for preventing HIV transmission to sexual partners and breastfed infants. Despite systemic viral suppression, genital HIV shedding may still occur in some…
View details →DOI: 10.1186/s12879-026-12621-2 Negative / Null Result ReportMedicine
Kambara M, Ikawa F, Hidaka T et al. · 2025 · Neurosurgery
Background and objectives Some reports suggest that older patients with traumatic brain injury (TBI) are more likely to experience acute intracranial hemorrhage, resulting in poor outcomes. However, the association between precise…
View details →DOI: 10.1227/neu.0000000000003240 Negative / Null Result ReportMedicine
Rodriguez JA, Palermo NE, Song W et al. · 2026 · Diabetes technology & therapeutics
Continuous glucose monitors (CGMs) are becoming increasingly available, yet the relationship between CGM metrics and hemoglobin A1c (HbA1c) among individuals with prediabetes and normoglycemia remains unclear. We examined associations…
View details →DOI: 10.1177/15209156251379506 Negative / Null Result ReportMedicine
de Luis D, Primo D, Izaola O et al. · 2024 · European review for medical and pharmacological sciences
Objective Sarcopenia is a condition characterized by muscle mass loss. Skeletal muscle is capable of producing and secreting different molecules called myokines, and apelin is one of them. The literature contains contradictory data on the…
View details →DOI: 10.26355/eurrev_202406_36461 Negative / Null Result ReportOpen accessMedicine
Leibold P, Lteif C, Duarte JD · 2025 · Frontiers in genetics
Introduction Hypertension (HTN) is a leading risk factor for several cardiovascular diseases. While some previous studies reported that CYP3A5 variants were associated with decreased blood pressure and risk of HTN, others reported no…
View details →DOI: 10.3389/fgene.2025.1490863 Negative / Null Result ReportOpen accessMedicine
Solanki JD, Joshi DR, Atodaria KA et al. · 2025 · Journal of family medicine and primary care
Introduction Cardiovascular health is adversely affected by menopausal transition with reduced heart rate variability (HRV) as a manifest. Electrocardiogram (ECG) based 5 min HRV has worsening trend from premenopausal to postmenopausal…
View details →DOI: 10.4103/jfmpc.jfmpc_274_25 Negative / Null Result ReportOpen accessMedicine
Chang RC, Olbrich H, Wang YF et al. · 2026 · JID innovations : skin science from molecules to population health
Bullous pemphigoid (BP) is an autoimmune blistering disease caused by autoantibodies to collagen type 17 ( COL17A1 ) and is a recognized immune-related adverse event in patients receiving immune checkpoint inhibitors (ICIs). We…
View details →DOI: 10.1016/j.xjidi.2026.100450 Negative / Null Result Report
Goldenholz DM, Cheng JC, Chang C et al. · 2025 · Preprint
ABSTRACT Importance Medication adherence is widely emphasized in epilepsy management, with a belief that missing even single doses can trigger seizures. However, scientific evidence supporting this specific claim is limited, particularly…
View details →DOI: 10.1101/2025.06.06.25329144 