Replication FailureMedicine
Cardon de Lichtbuer P, Declerck W, Rosseel Q et al. · 2026 · Journal of cataract and refractive surgery
Purpose To evaluate the effectiveness and usability of a safety-first, clinician-validated conversational artificial intelligence (AI) chatbot for cataract surgery education compared with standard brochures. Setting University Hospital (UZ…
View details →DOI: 10.1097/j.jcrs.0000000000001856 Replication FailureOpen accessMedicine
Ugail H, Howard N, Elmahmudi AA et al. · 2026 · Sensors (Basel, Switzerland)
Major depressive disorder remains difficult to diagnose objectively, as routine assessment is still largely dependent on clinical interview and rating scales. Resting-state electroencephalography (EEG) is an attractive complementary…
View details →DOI: 10.3390/s26103065 Negative / Null Result Report
Seffen AE, König LM, Dohle S · 2026 · Preprint
An increasing number of individuals aim to reduce their meat consumption, but implementing this is challenging. Self-control strategies could support this change; however, their effectiveness remains understudied. This study examines…
View details →DOI: 10.31234/osf.io/k8fvq_v1 Negative / Null Result ReportMedicine
Kiraly P, Lippera M, Ally N et al. · 2026 · Retina (Philadelphia, Pa.)
Purpose To assess whether external drainage of subretinal fluid (SRF) improves anatomical or visual outcomes in scleral buckle surgery for rhegmatogenous retinal detachment (RRD). Methods Retrospective review of 609 primary scleral buckles…
View details →DOI: 10.1097/iae.0000000000004856 Negative / Null Result ReportMedicine
Azulay N, Singstad BJ, Schirmer H et al. · 2026 · Scientific reports
In Norway, NORRISK2 is the government-recommended risk model for predicting an individual's 10-year probability of getting cardiovascular disease (CVD). This study aims to investigate the potential for improvement of CVD prediction by…
View details →DOI: 10.1038/s41598-026-57003-5 Negative / Null Result Report
Furukawa M, Narita M, Sakamoto I et al. · 2026 · Preprint
Abstract Background Six months of adjuvant S-1 is the standard treatment for resected pancreatic cancer in Japan. Metformin has demonstrated potential anticancer effects in preclinical and observational studies. This study aimed to…
View details →DOI: 10.21203/rs.3.rs-9445035/v1 Negative / Null Result ReportMedicine
Bröer S, Filor V, Bäumer W · 2026 · Journal of veterinary pharmacology and therapeutics
According to the European Association of Establishments for Veterinary Education (EAEVE), a graduate of veterinary medicine should be able to prescribe and dispense "medicines correctly and responsibly in accordance with legislation and…
View details →DOI: 10.1111/jvp.70062 Null Dataset
Leyva A, Niazi MKK · 2026 · Preprint
There have been no systematic evaluations of purely spectral models for digital pathology tasks. We implemented and benchmarked four pipelines: binary classification on the BreaKHis dataset, multi-class region classification in…
View details →DOI: 10.64898/2026.01.30.702908 Negative / Null Result ReportMedicine
Jegarl AM, Martin M, Cormier NR et al. · 2026 · Anesthesiology
Background Whether adding a bilateral superficial cervical plexus block to a thyroidectomy enhanced recovery pathway improves postoperative quality of recovery remains uncertain. Methods In a single-center prospective, randomized,…
View details →DOI: 10.1097/aln.0000000000006200 Negative / Null Result ReportMedicine
Jecan A, Melinte RM, Tomoaia G et al. · 2026 · Journal of clinical medicine
Background : Vitamin K2 (menaquinone) has been studied as a molecule with important effects on bone metabolism and has been proposed as a potential adjuvant in fracture healing, particularly under osteoporotic conditions. However, its…
View details →DOI: 10.3390/jcm15124510 Negative / Null Result ReportMedicine
Kılıç HS · 2026 · European journal of dentistry
Objective This article aims to compare the polymerization effectiveness of two curing modes of a polywave LED unit in four conventional resin composites at a 2-mm increment thickness, using bottom/top microhardness ratios as the evaluation…
View details →DOI: 10.1055/s-0046-1820081 Negative / Null Result ReportMedicine
Chang JJ, Foreman B, Kepplinger D et al. · 2026 · Neurosurgical review
Pressure reactivity index (PRx) is a surrogate for cerebral autoregulation and has been used for prognostication in aneurysmal subarachnoid hemorrhage (SAH). We examined patient-specific temporal courses of PRx and identified time…
View details →DOI: 10.1007/s10143-026-04323-9 Negative / Null Result ReportMedicine
Chun SH, Seo S, Cho JH et al. · 2026 · Head & neck
Background The benefit of consolidation programmed cell death protein 1 (PD-1) blockade after chemoradiotherapy in locoregionally advanced nasopharyngeal carcinoma (NPC) remains unclear. Methods Patients with stages II-IVB NPC were…
View details →DOI: 10.1002/hed.70329 Negative / Null Result ReportMedicine
Hongoro DJ, Kengne AP, Peer N et al. · 2026 · AIDS and behavior
Mobile health (mHealth) interventions offer scalable support for adherence and self-management, yet their effects on health-related quality of life (HRQoL) among people living with HIV (PLWH) and comorbid hypertension remain unclear. We…
View details →DOI: 10.1007/s10461-026-05128-z Negative / Null Result ReportMedicine
Yamamoto K, Shinno N, Omori T et al. · 2026 · Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association
Background Older patients undergoing gastrectomy frequently exhibit sarcopenia and reduced physiologic reserve, increasing vulnerability to perioperative muscle loss. However, randomized evidence supporting multimodal exercise-nutrition…
View details →DOI: 10.1007/s10120-026-01747-6 Negative / Null Result ReportMedicine
Dachy G, Mooyaart JE, Gabellier L et al. · 2026 · Bone marrow transplantation
Lymphodepleting conditioning (LD) with fludarabine and cyclophosphamide is critical to ensure optimal expansion and persistence of CD19 CAR T-cells. We conducted a retrospective EBMT registry study to assess the impact of fludarabine…
View details →DOI: 10.1038/s41409-026-02925-x Negative / Null Result ReportMedicine
Nasr MH, Abdulrasool Hassan B, Othman N et al. · 2026 · Journal of pharmaceutical policy and practice
Background Vitamin D deficiency is common among individuals with type 2 diabetes mellitus (T2DM) and has been linked to insulin resistance and poor glycaemic control. However, findings from randomised controlled trials remain inconsistent.…
View details →DOI: 10.1080/20523211.2026.2680824 Negative / Null Result ReportMedicine
Zorko K, Munda A, Janež A et al. · 2026 · American journal of obstetrics and gynecology
Background Self-monitoring of blood glucose represents the standard for glycemic monitoring in gestational diabetes mellitus, while the role of continuous glucose monitoring remains uncertain. Objective To assess whether adjunctive flash…
View details →DOI: 10.1016/j.ajog.2026.03.030 Negative / Null Result ReportMedicine
Kunz Coyne AJ, Gray R, Gonnabathula P et al. · 2026 · The Journal of antimicrobial chemotherapy
Background Stenotrophomonas maltophilia complex infections are difficult to treat because of intrinsic resistance mediated by the L1 metallo-β-lactamase and L2 serine β-lactamase. Although aztreonam/avibactam is clinically available,…
View details →DOI: 10.1093/jac/dkag177 Negative / Null Result ReportMedicine
Peretz-Kahlon M, Wood K, Harris A et al. · 2026 · Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
BACKGROUND: Branch retinal vein occlusion (BRVO) frequently results in macular edema (ME), impairing visual acuity (VA). Intravitreal anti-vascular endothelial growth factor (VEGF) injections are standard first-line therapy but the benefit…
View details →DOI: 10.1007/s00417-026-07227-y Negative / Null Result ReportMedicine
Mustafa YH, Keogh RJ, Barry SL et al. · 2026 · Irish journal of medical science
Background Glioblastoma is the most common malignant brain tumour in adults and carries a poor prognosis despite advances in molecular characterisation and therapy. The 2021 World Health Organisation classification redefined glioblastoma…
View details →DOI: 10.1007/s11845-026-04449-1 Negative / Null Result ReportMedicine
Arije D, Bista P, Gautam S et al. · 2026 · Field Crops Research.
Cultivated soils in arid and semi-arid regions are vulnerable to soil organic carbon (SOC) loss due to variable crop yields, residue removal, and frequent fallowing. Replacing fallow periods with cover crops has been promoted to increase…
Negative / Null Result ReportMedicine
Yi Y, Yano K · 2025 · Physiologia plantarum
Elevated CO 2 (eCO 2 ) can enhance plant growth, but it may also accelerate senescence, which could offset the growth benefits. Phosphorus (P) supply can enhance the photosynthetic rate under eCO 2 conditions and promote biomass…
View details →DOI: 10.1111/ppl.70470 Negative / Null Result Report
Liang H, Zhang D, An X et al. · 2026 · Preprint
Abstract The rise of generative AI (GenAI) has sparked interest in whether human-AI collaboration can enhance creativity, yet empirical findings remain mixed. This study systematically compared 4 collaboration models (i.e., AI-first,…
View details →DOI: 10.21203/rs.3.rs-8774138/v1 Negative / Null Result ReportMedicine
Gupta N, Seo J, Phan F et al. · 2026 · Heart rhythm
Background Lead dwell time (DT) is associated with increased complexity of cardiac implantable electronic device (CIED) extraction. Optimal strategies for risk mitigation are not well studied. Objective This study aimed to evaluate the…
View details →DOI: 10.1016/j.hrthm.2026.04.025 Negative / Null Result ReportMedicine
Chen YF, Kou HW, Chen TH et al. · 2026 · Journal of gastrointestinal cancer
Purpose Radical surgery is the primary treatment for localized gastric cancer (GC), but the benefit of adjuvant chemotherapy in stage IB GC remains unclear. This study evaluates its impact on recurrence and survival post-gastrectomy.…
View details →DOI: 10.1007/s12029-026-01472-4 Negative / Null Result ReportMedicine
Andrade A, Mureb M, Karaman N et al. · 2026 · Journal of neuro-oncology
PURPOSE: KRAS G12C mutations occur in approximately 11% of non-small-cell lung cancer (NSCLC) patients and are associated with aggressive disease and poor prognosis. Although KRAS G12C-inhibitors are now approved, their impact on Gamma…
View details →DOI: 10.1007/s11060-026-05547-x Negative / Null Result ReportMedicine
Mikami R, Imai S, Hayakawa M et al. · 2025 · Die Pharmazie
This study aimed to evaluate the temporal effect of a serum creatinine (SCr) correction intervention in critically ill patients with daily muscle wasting. A total of 5,355 critical care days in 574 patients with creatinine clearance (Clcr)…
View details →DOI: 10.1691/ph.2025.5569 Negative / Null Result ReportMedicine
Montenegro J, Oliveira CL, Nguyen NK et al. · 2026 · The Journal of nutrition
Background Excess body weight is associated with chronic low-grade inflammation and metabolic abnormalities, such as insulin resistance, and dyslipidemia. Objectives This study aimed to assess the impact of a soy protein-yogurt-honey…
View details →DOI: 10.1016/j.tjnut.2026.101595 Negative / Null Result ReportOpen accessMedicine
Bliesner RK, Stevens AA, Holling L et al. · 2026 · Cureus
Background Being in the large majority, right-handed people are not required to use their nondominant hands throughout their daily lives, resulting in a loss of motor dexterity. As technology continues to advance, improving motor dexterity…
View details →DOI: 10.7759/cureus.108025 