Negative / Null Result ReportOpen accessPhysics
Bahadir Tamer · 2021 · EPJ Web of Conferences
The MIT BEAVRS benchmark problem, which was primarily setup for the verification and validation of high-fidelity tools that have coupled neutron transport, thermal-hydraulics, and fuel isotopic depletion models, has also found extensive usage in the reactor physics community for validating core analysis tools. The primary purpose of this paper is to provide an accurate, comprehensive evaluation of the BEAVRS benchmark with CASMO5 and SIMULATE5 codes. The CMS5 calculated results for low-power physics tests (hot zero power critical boron, control rod worth and isothermal temperature coefficients
View details →DOI: 10.1051/epjconf/202124706022 Negative / Null Result ReportOpen accessInternal medicine
Cansu Önlen Güneri, Hamza Malik Okuyan, Gülay Gülbol Duran et al. · 2022 · Ķazaķstannyṇ Klinikalyķ Medicinasy
Aim: Patients infected with the hepatitis B virus (HBV) are at a higher risk of cirrhosis and hepatocellular carcinoma. Despite the recent advancement of antiviral therapy, many patients still cannot respond to existing therapies. Hence, to detect the changes in liver function earlier, non-invasive methods are needed. Long non-coding RNAs (lncRNAs) play important roles in essential biological process as well as human cancer. LncRNAs may be used as biomarkers in human diseases. Thus, in this study, we purposed to analyze the expression levels of lncRNAs (HOX transcript antisense RNA (HOTAIR), m
View details →DOI: 10.23950/jcmk/12662 Negative / Null Result ReportOpen accessMedicine (General)
M.C. Azevedo, E.D.R.P. Velloso, V. Buccheri et al. · 2014 · Brazilian Journal of Medical and Biological Research
In adults with non-promyelocytic acute myeloid leukemia (AML), high-dose cytarabine consolidation therapy has been shown to influence survival in selected patients, although the appropriate doses and schemes have not been defined. We evaluated survival after calculating the actual dose of cytarabine that patients received for consolidation therapy and divided them into 3 groups according to dose. We conducted a single-center, retrospective study involving 311 non-promyelocytic AML patients with a median age of 36 years (16-79 years) who received curative treatment between 1978 and 2007. The 13
View details →DOI: 10.1590/1414-431x20144059 Negative / Null Result ReportOpen accessMedicine
Yan Michael Li, Richard Francis Frisch, Zheng Huang et al. · 2021 · Asian Spine Journal
Study Design Retrospective chart review. Purpose This study compared the clinical and radiographic outcomes of patients treated with expandable and static interbody spacers following minimally invasive lateral lumbar interbody fusion (MIS-LLIF) with 12-month follow-up. Overview of Literature A common surgical option for the treatment of degenerative disk disease (DDD) is MIS-LLIF using static or expandable spacers to restore disk height (DH), neuroforaminal height (NH), and segmental lordosis. Static spacers may require excessive trialing and aggressive impaction, potentially leading to endpla
View details →DOI: 10.31616/asj.2019.0260 Negative / Null Result ReportOpen accessAgriculture (General)
WANG Xiaofan, WU Yong, ZHANG ZHONG Lili et al. · 2021 · Guan'gai paishui xuebao
【Background and Objective】 Magnetizing the water prior to irrigation is a new technology developed over the past decades in China. The objective of this paper is to investigate how different irrigation water sources alter the effects of the magnetization on photosynthesis, physiological and biochemical characteristics, as well as the yield of lettuce. 【Method】 The experiment was conducted in a solar greenhouse with the Italian lettuce taken as the model plant. It consisted of non-magnetization (M0) and magnetization (M1); added to these are three irrigation water sources: fresh water (T1), rec
View details →DOI: 10.13522/j.cnki.ggps.2020378 Negative / Null Result ReportOpen accessDentistry
Elanur Yıldızoğlu, Melih Manir, Muhammet Karadas · 2026 · BMC Oral Health
Abstract Background This in-vitro study aimed to assess the effects of whitening toothpastes on color and translucency changes and surface roughness of resin composites. Methods Disk-shaped resin composite samples from each composite (Clearfil Majesty Esthetic, Palfique Estelite Paste, and Charisma Smart) were made and randomly allocated into five groups (n = 10): Crest Pro Health Whitening, Advance White Pro, Sensodyne Extra Whitening, a control group (distilled water), and a positive control group (exposed to only stain). The samples were exposed to a tea solution and brushed for 30 days. Su
View details →DOI: 10.1186/s12903-026-08416-1 Negative / Null Result ReportOpen accessMedicine
Shermineh Heydari, Ladan Kashani, Mehrdad Noruzinia · 2021 · Iranian Journal of Allergy, Asthma and Immunology
Endometriosis is a common, chronic, inflammatory disorder in women, characterized by the presence of endometrial tissue outside the uterus cavity. The disease affects ~10% of women during their reproductive age. There is some debates on the pathogenesis of endometriosis and its mechanism among the scientists; therefore, different hypotheses have been suggested. According to Sampson theory, a possible mechanism for seeding ectopic endometriotic lesions is a dysregulation of endometrial mesenchymal stem cells (eMSCs). In the present study, we evaluated the expression of candidate genes in eMSCs
Negative / Null Result ReportOpen accessDiseases of the genitourinary system. Urology
Akash Bihari Pati, Pritinanada Mishra, Santosh K Mahalik et al. · 2023 · Indian Journal of Urology
Introduction: Proximal hypospadias repair has many postoperative complications such as urethrocutaneous fistulae, wound dehiscence, and urethral stricture. The beneficial effect of estrogen to promote wound healing has been known. We designed a study to determine whether preoperative stimulation of tissue with estrogen can reduce the postoperative complications associated with wound healing in patients undergoing hypospadias repair. Methods: Patients with proximal hypospadias requiring two-stage repairs (chordee correction followed by urethral tubularization) were randomized to estrogen and co
View details →DOI: 10.4103/iju.iju_387_22 Negative / Null Result ReportOpen accessAnimal culture
Heng Wang, Lin Liu, Xi He et al. · 2025 · The Journal of Poultry Science
Betaine has been proposed as a low-cost source of methyl groups in poultry feed, replacing methionine and choline. The present study aimed to investigate the effect of betaine on growth performance, methionine metabolism, and methyl transfer in broilers aged 1 to 21 days fed a low-methionine diet. A total of 960 one-day-old male broilers were randomly divided into four groups: positive control (0.62% methionine in the diet), negative control (0.37% methionine in the diet), and two treatment groups (0.37% methionine in the diet plus either 1500 or 3000 mg betaine/kg diet). Chicks fed the 1500 m
View details →DOI: 10.2141/jpsa.2025010 Negative / Null Result ReportOpen accessMedicine
Bilinç Doğruöz Karatekin, Şeyhmus Yasin, Yasemin Yumuşakhuylu et al. · 2021 · Bagcilar Medical Bulletin
Objective:Sarcopenia and osteoporosis share common risk factors and biological pathways. In the present study, patients with postmenopausal osteoporosis were screened for sarcopenia using the algorithm proposed by the European Working Group on Sarcopenia in Older People (EWGSOP) and balance impairment was investigated in sarcopenic patients.Method:Fifty three postmenopausal osteoporotic patients were evaluated for sarcopenia as per the algorithm proposed by the EWGSOP. Among the parameters included in the algorithm, gait speed was assessed using the timed up&go test (TUG), Jamar hand dynamomet
View details →DOI: 10.4274/bmb.galenos.2021.03.034 Negative / Null Result ReportOpen accessEducation (General)
Nur Maziyah Ulya · 2016 · Nadwa
This study aims to analyze: (1) The difference of students‟ achievement between students studying at cooperative learning class and those studying at conventional learning class; (2) The difference of students‟ achievement between the introvers and the extroverts; (3) The interactive influence between learning method and students‟ personality type toward students‟ achievement in Arabic language. This research used experimental design conducted at MAN 1 Semarang.. The result of this research shows that: (1) There is significant difference in students‟ achievement between students studying at th
View details →DOI: 10.21580/nw.2016.10.1.867 Negative / Null Result ReportOpen accessPharmacy and materia medica
Comfort Nanbam Sariem, Maxwell Patrick Dapar, Nenman Musa Lenka et al. · 2022 · INNOVATIONS in Pharmacy
Background: The prolonged multi-drug treatment regimen for tuberculosis (TB) can lead to non-adherence and unsuccessful treatment outcomes. Educational and psychological health models can be used to design cognitive and behavioral interventions to improve adherence and treatment outcomes. Objective: To determine the effect of cognitive and behavioral interventions on TB treatment outcomes. Methods: The quasi-experimental study conducted in six TB treatment centers involved reinforced medication education and adherence counseling (MEAC), designed from a structured validated psychometric scale.
View details →DOI: 10.24926/iip.v13i4.5031 Negative / Null Result ReportOpen accessAgriculture (General)
LI Yexin, LYU Gang, WANG Daohan et al. · 2023 · Guan'gai paishui xuebao
【Objective】 Restoring coal mining waste dumps is a way to alleviate their detrimental impact on environment. In this paper, we present the results of an experimental study on distribution and stability of soil aggregates in a reclaimed coal mining overburden dump. 【Method】 The experiment was carried out at a reclaimed coal mine dump site in a grassland region in northern China. We measured the development of fissures from Zone I (GF) to Zone three (GFIII) in the fissure zone. The composition and distribution soil aggregates in these zones were determined using dry-wet sieve method. Aggregate s
View details →DOI: 10.13522/j.cnki.ggps.2021419 Negative / Null Result ReportOpen accessVocational rehabilitation. Employment of people with disabilities
Zahid Mehmood, Zubair Ahmad, Asad Ullah et al. · 2023 · The Rehabilitation Journal
Background: Understanding students' perception of the educational environment and their cognitive load in this context is crucial for optimizing the effectiveness of e-learning platforms. Objective: To compare educational environment perception and cognitive load in under-graduates Doctor of Physical Therapy (DPT) and post-graduate Master in Science of Physical Therapy (MSPT) students having online learning experiences. Methodology: In this comparative cross-sectional study, data was collected through non-probability convenient sampling from n=274 under-graduates DPT (n=225) and post-graduates
View details →DOI: 10.52567/trj.v7i02.224 Negative / Null Result ReportOpen accessArchaeology
Solodovnikov K.N., Kravchenko G.G., Rykun M.P. · 2018 · Вестник археологии, антропологии и этнографии
This paper is aimed at scrutinizing the dependence between the morphological features of the Eneolithic — Early Bronze population and the geographical and bioclimatic conditions in the Altai valleys and intermountain basins. Across the territory of the Altai highlands, we have identified several local-territorial groups of archaeological sites dating to the period under study. Most of them belong to the Afanasyevо culture, with the rest being represented by the Kurota, Aragol and Ulita cultural types that have been recently designated from the Afanasyevо culture. For each group, in accordance
View details →DOI: 10.20874/2071-0437-2018-43-4-120-135 Negative / Null Result ReportOpen accessMedicine
Qais A. AL-Oqaily · 2016 · The Iraqi Journal of Medical Sciences
Background:Several studies have demonstrated the role of hematological parameters like hemoglobin (Hb), white blood cells (WBC) count and platelet count in the assessment of patients with coronary artery disease; some studies suggest an additional role of platelet indices in the prognosis of patients with coronary artery disease. Objective:To assess complete blood count and platelet indices in patients with coronary artery disease. Methods: Blood sample of 42 newly diagnosed ischemic heart disease patients including 20 patients with myocardial infarction (MI) and 22 patients with unstable angi
Negative / Null Result ReportOpen accessComputer applications to medicine. Medical informatics
Siemer, Lutz, Brusse-Keizer, Marjolein G J, Postel, Marloes G et al. · 2020 · Journal of Medical Internet Research
BackgroundBlended face-to-face and web-based treatment is a promising way to deliver smoking cessation treatment. Since adherence has been shown to be an indicator of treatment acceptability and a determinant for effectiveness, we explored and compared adherence and predictors of adherence to blended and face-to-face alone smoking cessation treatments with similar content and intensity. ObjectiveThe objectives of this study were (1) to compare adherence to a blended smoking cessation treatment with adherence to a face-to-face treatment; (2) to compare adherence within the blended treatment to
View details →DOI: 10.2196/17207 Negative / Null Result ReportOpen accessSurgery
Yasuhiro Nagatani MD, Naoki Segi MD, Sadayuki Ito MD et al. · 2026 · Global Spine Journal
Study Design Retrospective cohort study. Objectives Successful bone fusion is crucial for favorable posterior lumbar interbody fusion (PLIF) outcomes. While trabecular bone remodeling (TBR) indicates osseointegration, its interpretation remains uncertain. This study aimed to clarify the clinical significance of distinct TBR types—fine TBR (fTBR) and sclerotic TBR (sTBR)—as seen on computed tomography (CT) scans and to evaluate their predictive value for segment stabilization and complete bone fusion and their relationship with interbody cage materials. Methods Seventy-one patients who underwen
View details →DOI: 10.1177/21925682251385533 Negative / Null Result ReportOpen accessMedicine
Ted Lee, Heiko Yang, David Haneuer et al. · 2018 · Hospital Practices and Research
Background: Iatrogenic urethral injury is a well-known risk of urinary catheter insertion. Associated morbidities include stricture formation, catheter associated infection, risk for instrumentation, and extended length of stay. Yet, insufficient attention is paid to its prevention. Objective: This study aimed to assess the effectiveness of a computerized ordering system in reducing iatrogenic urethral injuries in men at high risk for iatrogenic urethral injury from traumatic catheterization. Methods: A pre-post study was performed to assess the impact of a computerized ordering system that re
View details →DOI: 10.15171/hpr.2018.06 Negative / Null Result ReportOpen accessPsychiatry
S. Javed, R. K. Gaur, A. Ibrahim et al. · 2017 · Sri Lanka Journal of Psychiatry
Background Dementia is a common, disabling disorder of the elderly. With the steady growth in the older population, the rate of dementia is expected to increase two fold by 2030 and three fold by 2050. Dementia of Alzheimer Type (DAT) and vascular dementia (VD) are among the most common types of dementia. Behavioral and psychological symptoms of dementia (BPSD) are associated with increased patient morbidity and carer burden. Aims The objective of this study was to compare symptoms of BPSD in patients with DAT and VD and to explore the correlates of BPSD in patients with DAT and VD. Methods Pe
View details →DOI: 10.4038/sljpsyc.v8i1.8136 Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens
Kai Zhou, Anqiang Wang, Jingtao Wei et al. · 2022 · Frontiers in Oncology
BackgroundHepatoid adenocarcinoma of the stomach (HAS) is a rare type of gastric cancer, but the role of perioperative chemotherapy is still poorly understood. The aim of this retrospective study was to investigate the associations between perioperative chemotherapy and prognosis of HAS.MethodWe retrospectively analyzed patients with locally advanced HAS who received radical surgery in Peking University Cancer Hospital between November 2009 and October 2020. Patients were divided into neoadjuvant chemotherapy-first (NAC-first) group and surgery-first group. The relationships between perioperat
View details →DOI: 10.3389/fonc.2021.789104 Negative / Null Result ReportOpen accessDentistry
Ika Devi, Erliera Sufarnap, Finna et al. · 2023 · Dental Journal
Background: Chitosan has an antimicrobial effect in oral hygiene control. Orthodontists sometimes prescribe mouthwash to adolescent patients. Copper-nickel-titanium (CuNiTi) orthodontic archwire is widely used in orthodontic treatment. Chitosan’s effects on the CuNiTi properties of orthodontic archwire are not generally known. Purpose: This study aimed to measure the acidity, copper ion release, deflection, and surface roughness of CuNiTi orthodontic archwire immersed in artificial saliva and 2% chitosan. Methods: This study comprised experimental laboratory research. Forty-two CuNiTi orthodon
View details →DOI: 10.20473/j.djmkg.v56.i1.p41-47 Negative / Null Result ReportOpen accessMedicine
Ghalib A Akinlabi, Paul L Kaufman, Julie A Kiland · 2021 · PLoS ONE
Purpose In earlier experiments in Nigeria, aqueous extract of Pleurotus tuber-regium (PT) had been shown to lower intra ocular pressure (IOP) in a feline model. The aim of the current study was to determine whether PT had the same or a similar IOP-lowering effect in ocularly normal non-human primates. Methods Four monkeys were treated twice daily for 4 days with 2 x 20 μl drops of 50 mg/ml PT (pH = 4.3). The monkeys were sedated with 5-10 mg/kg ketamine HCl IM. PT was administered to the right eye and BSS to the left eye. Baseline IOP was measured just prior to beginning treatment, and on day
View details →DOI: 10.1371/journal.pone.0256422 Negative / Null Result ReportOpen accessTherapeutics. Pharmacology
O. A. Saygina, T. S. Sukhinina, M. A. Terenicheva et al. · 2026 · Рациональная фармакотерапия в кардиологии
Aim. To study the safety of using the intravenous beta-blocker (BB) esmolol in the early stages of ST-segment elevation myocardial infarction (STEMI) before primary percutaneous coronary intervention (PCI) based on an analysis of the incidence and clinical significance of adverse events (acute heart failure, hypotension, bradycardia, disorders of atrioventricular conduction (AV conduction), etc.) compared with the control group.Material and methods. The presented study is part of the randomized controlled trial ESMO-VASCMI (ClinicalTrials.gov NCT number 06376630) on the study of the cardioprot
View details →DOI: 10.20996/1819-6446-2025-3241 Negative / Null Result ReportOpen accessMedicine
Shurong Huang, Zhe Su, Huiping Su et al. · 2022 · Scientific Reports
Abstract Estrogen can promote the acceleration of bone maturation and phthalate esters (PAEs) have estrogen-mimicking effects. We investigated whether PAEs are associated with the acceleration of bone age (BA) in girls with early onset of puberty (EOP). This case–control study enrolled 254 girls with EOP from the Endocrinology Department at Shenzhen Children’s Hospital between December 2018 and August 2019. Ultra-performance liquid chromatography and tandem mass spectrometry were used to analyze the 10 metabolites of PAEs (mPAEs) in urine samples. BA was measured using an artificial intelligen
View details →DOI: 10.1038/s41598-022-19470-4 Negative / Null Result ReportOpen accessDiseases of the blood and blood-forming organs
Edvan de Queiroz Crusoe, Fabiana Higashi, Maria Paula Nalesso Camargo Padilha et al. · 2014 · Revista Brasileira de Hematologia e Hemoterapia
Background: Induction therapy followed by high-dose chemotherapy and autologous transplantation is the standard treatment for suitable patients with multiple myeloma. Objective: The aim of this study was to assess whether induction therapy with thalidomidecontaining regimens was associated with improved results compared to vincristine, doxorubicin, and dexamethasone, and whether cyclophosphamide, thalidomide, and dexamethasone were associated with better results than thalidomide and dexamethasone. Methods: The records of 152 patients who underwent autologous transplantation at this institution
View details →DOI: 10.5581/1516-8484.20140008 Negative / Null Result ReportOpen accessSpecial aspects of education
Élida de Fátima Diniz Souza, Ana Paula Ramos Machado, José Danúzio Leite de Oliveira et al. · 2025 · BMC Medical Education
Abstract Background In Brazil, residency programmes in Family and Community Medicine (FCM) and Multiprofessional Residency in Family Health (MRFH) are two-year specialisation courses, funded by the federal government, which aim to train professionals to work in Primary Health Care (PHC). The aim of this study was to draw up an inventory of the assessed competences of the residency programmes in the state of Paraíba, Brazil. Our study’s hypothesis is that self-assessment of competences can be a useful tool for monitoring the development of competences in the training of health professionals, co
View details →DOI: 10.1186/s12909-025-07521-z Negative / Null Result ReportOpen accessMedicine
Christine B. French, Sharon L. McDonnell, Reinhold Vieth · 2019 · Journal of Medical Case Reports
Abstract Background Vitamin D nutrition research requires accurate measures of circulating 25-hydroxyvitamin D. Our objectives were to test whether a diurnal fluctuation in blood-spot concentrations of 25-hydroxyvitamin D can be demonstrated statistically in a single individual, and whether such fluctuation is affected by the pre-dose versus post-dose timing of the blood draw. Case presentation The participant in this case study was a generally healthy Caucasian woman in her 40s who has taken 5000 IU vitamin D3 supplement at midday for over 1 year. Each blood sample was drawn individually from
View details →DOI: 10.1186/s13256-018-1948-9 Negative / Null Result ReportOpen accessSpecial aspects of education
Wei Han Hong, Jamunarani Vadivelu, Esther Gnanamalar Sarojini Daniel et al. · 2015 · Medical Education Online
Background: Studies have shown the importance of metacognition in medical education. Metacognitive skills consist of two dimensions: knowledge of metacognition and regulation of metacognition. Aim: This study hypothesizes that the knowledge and regulation of metacognition is significantly different at the beginning and end of the academic year, and a correlation exists between the two dimensions of metacognitive skills with academic performance. Methods: The Metacognitive Skills Inventory comprising 52 Likert-scale items was administered to 159 first-year medical students at the University of
View details →DOI: 10.3402/meo.v20.27561 Negative / Null Result ReportOpen accessGynecology and obstetrics
Bingqian Zhang, Lianbao Cao, Lingling Ding et al. · 2017 · Gynecology and Minimally Invasive Therapy
Objective: To evaluate the effects of different treatment methods for previous ectopic pregnancies (EP) on cryopreserved embryo transfer (CET) outcomes. Materials and Methods: This was a retrospective cohort study. Patients with EP histories were divided into four groups based on their previous EP treatments: Group 1—unilateral tubal removal; Group 2—bilateral tubal removal or unilateral tubal removal with contralateral tubal ligation; Group 3—conservative surgery group; and Group 4—conservative medication group. A total of 1333 women with previous histories of being admitted to the hospital f
View details →DOI: 10.1016/j.gmit.2017.01.001 