Negative / Null Result ReportMedicine
Luo X, Ma N, Yang Y et al. · 2026 · BMC surgery
Objective Proximal femoral bionic nail (PFBN) represents a novel biomechanical design for the internal fixation of intertrochanteric fractures in older adults. However, comparative real-world evidence between PFBN and the conventional…
View details →DOI: 10.1186/s12893-026-03937-6 Negative / Null Result ReportMedicine
Thompson GE, Wesemann LB, Ogundipe EA et al. · 2026 · Fetal diagnosis and therapy
Prenatal diagnoses of Congenital Anomalies of the Kidney and Urinary Tract (CAKUT) are critical for counseling families about potential postnatal outcomes. While ultrasound (US) remains the gold standard for prenatal diagnosis of CAKUT,…
View details →DOI: 10.1159/000552627 Negative / Null Result ReportMedicine
Kultanaruangnonth M, Chatrung L, Tansawet A et al. · 2026 · World journal of emergency surgery : WJES
Background Surgical site infections (SSIs) remain a major concern after abdominal surgery, with incidences of 15-22%. Intraoperative wound irrigation (IOWI) before closure is routinely performed to reduce bacterial contamination, but the…
View details →DOI: 10.1186/s13017-026-00705-y Negative / Null Result ReportMedicine
Geng YQ, Ding Y, Fu CG et al. · 2026 · Zhonghua yi xue za zhi
Objective: To compare the efficacy between endoscopic submucosal dissection (ESD) combined with low-dose radiotherapy and direct surgical resection in patients with T1a-MM/T1b-SM stage esophageal squamous cell carcinoma. Methods: A…
View details →DOI: 10.3760/cma.j.cn112137-20251024-02757 Negative / Null Result ReportOpen accessMedicine
Bader SE, Magnuson A, Brorsson C et al. · 2026 · European journal of trauma and emergency surgery : official publication of the European Trauma Society
Background Resuscitative endovascular balloon occlusion of the aorta (REBOA) is used as an adjunct in haemorrhagic shock (HS) to restore proximal perfusion. Its cerebral metabolic effects during haemorrhagic shock, particularly in the…
View details →DOI: 10.1007/s00068-026-03147-y Negative / Null Result ReportOpen accessMedicine
Arslan Çarpar K, Yılmaz T · 2026 · BMC oral health
BACKGROUND: This study aimed to compare the plaque removal efficacy of manual and powered toothbrushes around attachments in patients undergoing clear aligner therapy under standardized, single-brushing conditions. METHODS: This…
View details →DOI: 10.1186/s12903-026-08395-3 Negative / Null Result ReportMedicine
Hakkani Öznay Ç, Findik H, Uzun F et al. · 2026 · Journal of clinical medicine
Objectives : To prospectively compare the outcomes of external dacryocystorhinostomy (EX-DCR), endonasal dacryocystorhinostomy (EN-DCR), and laser-assisted transcanalicular dacryocystorhinostomy (TL-DCR) in patients with nasolacrimal duct…
View details →DOI: 10.3390/jcm15124488 Negative / Null Result Report
Sorjonen K, Melin B, Melin M · 2026 · Preprint
Ji et al. recently reported evidence suggesting that marital satisfaction serves as a longitudinal protective factor against postpartum depressive symptoms, basing this conclusion on statistically significant paths estimated with…
View details →DOI: 10.31234/osf.io/wrf3x_v1 Negative / Null Result ReportMedicine
Smith A, Dixit I, Zhang L et al. · 2026 · JAMA dermatology
Importance Cardiovascular disease (CVD) is the leading cause of mortality in patients with psoriasis, yet structured CVD prevention is not routinely embedded in dermatology care. Objective To evaluate the effectiveness of a text-messaging…
View details →DOI: 10.1001/jamadermatol.2026.1070 Negative / Null Result ReportOpen accessMedicine
Parkhoo K, Schmitz LA, Fröb L et al. · 2026 · Dentistry journal
Objectives : Six dentin adhesives were tested in vitro regarding their cytotoxicity toward human fibroblasts. AdheSE, Clearfil SE Bond, Hybrid Bond, One-up Bond F Plus, Optibond Solo Plus, and Syntac were tested using a cell culture model.…
View details →DOI: 10.3390/dj14050312 Negative / Null Result ReportOpen accessMedicine
Korodimos N, Wojtyś ME, Kostopanagiotou K et al. · 2026 · Journal of clinical medicine
Background: Non-small-cell lung cancer (NSCLC) is driven by distinct oncogenic alterations with important therapeutic and prognostic implications. Noninvasive biomarkers that predict molecular status in surgically resectable disease may…
View details →DOI: 10.3390/jcm15114100 Negative / Null Result ReportOpen accessMedicine
Mahajan A, Haideri S, Kumar VVH et al. · 2026 · Journal of education and health promotion
Background The oral health is an integral part of general well-being in children suffering from attention deficit hyperactivity disorder (ADHD). The present study aimed to analyze the impact of oral health education program on children…
View details →DOI: 10.4103/jehp.jehp_1102_25 Negative / Null Result ReportOpen accessMedicine
Abdi A, Abbasi E, Abazarlou A · 2026 · BMC neurology
Objectives Migraine is a common and disabling neurological disorder in children, often requiring preventive treatment. This study aimed to compare the efficacy and tolerability of cinnarizine and topiramate in the prophylaxis of migraine…
View details →DOI: 10.1186/s12883-026-04950-1 Negative / Null Result ReportMedicine
Peker N, Yücetürk A, Tığlı E et al. · 2026 · Journal of ovarian research
Background We aimed to evaluate whether delayed initiation of gonadotropin hormone-releasing hormone (GnRH) antagonist treatment affects premature ovulation and the number of good-quality blastocysts. We retrospectively reviewed the…
View details →DOI: 10.1186/s13048-026-02161-3 Negative / Null Result ReportOpen accessMedicine
Yan Z, Jiang Q, Lu Z et al. · 2026 · International journal of general medicine
Background Intervertebral disc degeneration (IVDD) is a major cause of low back pain. Observational studies suggest a link with gut microbiota (GM), possibly mediated by systemic inflammation, but causality remains unclear. Objective To…
View details →DOI: 10.2147/ijgm.s615488 Negative / Null Result ReportOpen accessMedicine
Ilbekova K, Ibrayeva D, Saifulina E et al. · 2026 · Journal of clinical medicine
Background/Objectives : Cancer incidence and mortality are key epidemiological indicators for evaluating the long-term biological effects of chronic low-dose radiation exposure. The aim of this study was to assess the incidence, structure,…
View details →DOI: 10.3390/jcm15114330 Negative / Null Result Report
Plaikner A, Ploner M, Sewald Z et al. · 2026 · Preprint
Protein Language Models (pLMs) have significantly advanced computational biology. Yet their scale and reliance on redundant training data raise a fundamental question: do pLMs generalize the statistical grammar of proteins, or do they…
View details →DOI: 10.64898/2026.06.08.730685 Negative / Null Result ReportMedicine
Shan J, Yu J, Zhao L et al. · 2026 · BMC cancer
Background Dose reduction during concurrent chemoradiotherapy (cCRT) is frequently required in patients with limited-stage small-cell lung cancer (LS-SCLC) because of treatment-related toxicities or poor tolerance. However, the impact of…
View details →DOI: 10.1186/s12885-026-16150-8 Negative / Null Result Report
Mohammed S, Kyei L, Okyere F et al. · 2026 · Preprint
Abstract Background: PAM50 molecular subtype is an established prognostic factor in breast cancer, yet unmeasured heterogeneity may persist within and between subtypes. We evaluated whether shared frailty modeling provides additional…
View details →DOI: 10.21203/rs.3.rs-9931861/v1 Negative / Null Result ReportOpen accessMedicine
Alkhalifah OF, Ali Shah S, Tareen SUK et al. · 2026 · Cureus
Background Achieving a lifelike color match for anterior restorations is a persistent challenge because tooth appearance is heavily influenced by illumination and observer-dependent choices. While visual matching with VITA-type guides…
View details →DOI: 10.7759/cureus.108421 Negative / Null Result Report
Kiplimo D, Sperber S, Nata’ala MK et al. · 2026 · Preprint
Abstract Background Antimicrobial resistance (AMR) in plant-associated microbiomes is increasingly recognized as One-Health concern. Apples are widely consumed, yet little is known about how agricultural practices and geography shape its…
View details →DOI: 10.21203/rs.3.rs-9344661/v1 Negative / Null Result ReportOpen accessMedicine
Matsumoto T, Yamamoto Y, Kotaka M et al. · 2024 · Targeted oncology
Background Non-inferiority of trifluridine/tipiracil (FTD/TPI) plus bevacizumab (BEV) to irinotecan/fluoropyrimidine plus BEV in metastatic colorectal cancer was investigated in the phase III TRUSTY study, and we conducted a phase II study…
View details →DOI: 10.1007/s11523-024-01043-2 Negative / Null Result ReportOpen access
Halpin M, Lerner A, Sagar M et al. · 2023 · Preprint
The systemic inflammatory response seen in patients with severe COVID-19 shares many similarities with the changes observed in hemophagocytic lymphohistiocytosis (HLH); a disease characterized by excessive immune activation. Many patients…
View details →DOI: 10.1101/2023.06.05.23290969 Negative / Null Result ReportMedicine
Webers C, Ortolan A, Sepriano A et al. · 2023 · Annals of the rheumatic diseases
Objective To update the evidence on efficacy and safety of biological disease-modifying antirheumatic drugs (bDMARDs) in patients with axial spondyloarthritis (axSpA) to inform the 2022 update of the Assessment of SpondyloArthritis…
View details →DOI: 10.1136/ard-2022-223298 Negative / Null Result ReportOpen accessMedicine
Ma XT, Yao GY, Li JL et al. · 2025 · World journal of clinical oncology
Background Human epidermal growth factor receptor 2 (HER2)-positive gastric cancer (GC) represents a distinct molecular cancer subtype that is often associated with a poor prognosis. While perioperative chemotherapy regimens are currently…
View details →DOI: 10.5306/wjco.v16.i11.112029 Negative / Null Result ReportMedicine
Kotian RN, Ajoy SM, Panduranga R et al. · 2026 · The bone & joint journal
Aims There are conflicting results in the literature regarding the safety of the peroneus longus tendon (PLT) as a potential graft for anterior cruciate ligament (ACL) reconstruction, and no long-term studies with objective assessment…
View details →DOI: 10.1302/0301-620x.108b6.bjj-2025-0274.r1 Negative / Null Result ReportMedicine
Tankuş M, Memikoğlu TUT · 2026 · BMC oral health
Background This study aimed to investigate enamel surface changes after debonding of teeth with metal and ceramic brackets exhibiting varying severities of white spot lesions (WSLs). Methods Forty healthy premolars were divided into two…
View details →DOI: 10.1186/s12903-026-08860-z Negative / Null Result ReportOpen accessMedicine
Chereji G, Chelaru VF, Nicoară SD · 2026 · Diagnostics (Basel, Switzerland)
Background/Objectives : Rhegmatogenous retinal detachment (RRD) is a surgical emergency that causes vision loss if not properly treated. Pars plana vitrectomy (PPV) is the preferred procedure for most complex RRD cases, with a high success…
View details →DOI: 10.3390/diagnostics16111696 Negative / Null Result ReportOpen accessMedicine
Wang Z, Zhang Y, Zhang K et al. · 2026 · Experimental and therapeutic medicine
Within the present study, the aim was to investigate the dynamic changes in iron metabolism parameters in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI) and to…
View details →DOI: 10.3892/etm.2026.13173 Negative / Null Result ReportOpen accessMedicine
Liu J, Liu M, Xu Y et al. · 2026 · Clinics (Sao Paulo, Brazil)
Background BOS172722, a selective TTK inhibitor, shows promise for Breast Cancer (BC) treatment. The role of gut microbiota as a potential mediator in this process has not been established. This Mendelian Randomization (MR) study…
View details →DOI: 10.1016/j.clinsp.2026.100961 