A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21707 results · page 242 of 724
Bello RJ, Palleiko BA, Kennedy K et al. · 2024 · Surgical oncology
Background Pain management following mastectomy is a significant challenge often requiring opioids. Nonopioid pain management utilizing nerve blocks has been shown in other fields to reduce postoperative opioid use and may be effective for…
Pan L, Kaku Y, Tolentino JE et al. · 2025 · Frontiers in microbiology
In the 21st century, three severe human coronavirus infections have occurred. One of them is the Middle East respiratory syndrome coronavirus (MERS-CoV), a merbecovirus belonging to the family Coronaviridae , is a human pathogenic…
Khan M, Yousaf H, Naqqash M et al. · 2025 · Cureus
Introduction There is limited local data comparing the outcomes of core decompression and fibular strut grafting in early-stage avascular necrosis (AVN) of the hip. International findings may not be directly applicable due to…
Yaşar NF, Badak B, Salış M et al. · 2024 · Revista da Associacao Medica Brasileira (1992)
Objective Endogenous melatonin is produced from tryptophan which is an essential amino acid. Besides its role in the regulation of sleep patterns, melatonin has anti-inflammatory effects. In this case-control study, we aimed to compare…
Beaulieu A, Saint-Georges C, Hagbarth I et al. · 2026 · Scientific reports
General movements (GMs) refer to infants’ spontaneous motor activities before the emergence of voluntary motor activity. Abnormal GMs in neonates have been regarded as a marker of poor neurodevelopmental outcomes, with preliminary findings…
Iljazi A, Sørensen MS, Winther-Jensen M et al. · 2024 · Acta orthopaedica
Background and purpose Dislocation is a severe complication following total hip arthroplasty (THA). Hip precautions have been recommended in the initial postoperative period but evidence supporting this practice is limited. We therefore…
Klüwer B, Gleditsch R, Rydland KM et al. · 2024 · Vaccine
Aims To explore public confidence in influenza vaccination through the use of attitudinal indicators, and study whether educational attainment is related to attitudes towards influenza vaccination. Methods Confidence in influenza…
Jang S, Gwak HS, Joo J et al. · 2024 · Acta neurochirurgica
Purpose This study aimed to evaluate the symptomatic response and side effects of ventriculolumbar perfusion (VLP) methotrexate chemotherapy with a low perfusion rate in patients with leptomeningeal metastasis. Methods Patients in a…
Chen J, Hou S, Feng R et al. · 2023 · Preprint
CRISPR homing gene drive is a potent technology with considerable potential for managing populations of medically and agriculturally significant insects. It induces a bias in the inheritance of the drive allele in progeny, rapidly…
nema sk, ramsubramani P, S s · 2023 · Preprint
Abstract Background Transmembrane proteins of the Wnt family and receptor tyrosine kinase (ROR1 and ROR2) suppression or overexpression has been implicated in the causation of cancers. We determined the expression of ROR2 among patients of…
Mann S, Juhl CB, Paarup HM et al. · 2024 · Work (Reading, Mass.)
Background Playing the violin often requires a rotated and lateral flexed neck, leading to potential neck and shoulder problems. An ergonomic chinrest (EC) with or without a shoulder rest (SR or WSR) may enhance neutral neck positioning,…
Wiener RC, Abuhalimeh B, Cochran J · 2025 · Community dentistry and oral epidemiology
Objective The objective of this research was to determine if the ratio of family income to poverty index is a modifier in the relationship of sugar-sweetened beverages (SSB) and dental caries in U.S. children. Methods A cross-sectional…
Schwarzer NH, Behringer N, Dees P et al. · 2026 · BMC psychology
Background The Epistemic Trust, Mistrust, and Credulity Questionnaire (ETMCQ) assesses individual differences in epistemic stances. Although widely used, its German translation has not yet undergone an independent psychometric evaluation.…
Taniajura N, Rincon C, Kennedy S et al. · 2026 · Addictive behaviors reports
Research has demonstrated that exposure to alcohol-related cues (e.g., sight or smell of a preferred beverage) elicits heightened self-reported craving and psychophysiological responses, including changes in heart rate (HR) and heart rate…
Barrera G, Albiach-Serrano A, Guillén-Salazar F · 2024 · Animal cognition
Studies have shown that horses are sensitive to human attentional cues. Also, there is some evidence that they might be able to infer the knowledge state of a human and communicate intentionally with us. However, this ability is not fully…
Bansal M, Mehta A, Morris DL et al. · 2025 · Proceedings (Baylor University. Medical Center)
Background This study sought to assess the outcomes of pulmonary embolism (PE) admissions at teaching and nonteaching hospitals in the month of July, when new trainees begin their training in the United States. Methods During 2016-2021,…
Ruiz VH, Gill CM, Nicolau DP · 2024 · The Journal of antimicrobial chemotherapy
Objectives To evaluate the efficacy of human-simulated regimens (HSRs) of ceftazidime, ceftazidime/avibactam, imipenem, imipenem/relebactam, meropenem and meropenem/vaborbactam in a murine thigh infection model against serine…
Schaefer M, Liedtke C, Enge S · 2025 · Scientific reports
Recent reports challenge the view that placebos need to be given in deception. Numerous studies report remarkable effects when giving placebos honestly in an open way. However, the mechanisms of open-label placebos still remain to be…
Tortolani AF, Kunigk NG, Sobinov AR et al. · 2025 · Journal of neural engineering
Objective . As brain-computer interface (BCI) research advances, many new applications are being developed. Tasks can be performed in different virtual environments, and whether a BCI user can switch environments seamlessly will influence…
Rogers ER, Sankarasubramanian V, Kyi WHT et al. · 2025 · Journal of pain research
Purpose The analgesic mechanisms and neurophysiological effects of spinal cord stimulation (SCS) and dorsal root ganglion stimulation (DRGS) are poorly understood. In this pilot repeated-measures study, we used quantitative sensory testing…
Mauz JB, Rieland H, Berliner D et al. · 2024 · Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
Background & aims Considerate patient selection is vital to ensure the best possible outcomes after transjugular intrahepatic portosystemic shunt (TIPS) insertion. However, data regarding the impact of intrapulmonary vascular dilatations…
Seaman RW Jr, Shariatzadeh N, Salinas KA et al. · 2026 · Drug and alcohol dependence
Background Stimulant-opioid co-use has surged in the United States, with methamphetamine use among people who use opioids increasing 82.6 % from 2015 to 2017. This trend contributes to rising overdose deaths, marking a "fourth wave" of the…
Lilley A, Chiapponi C, Prosperi A et al. · 2026 · Vaccines
Background/Objectives : Influenza A viruses cause seasonal epidemics of respiratory infections in humans, the severity of which can be mitigated by influenza vaccine use. Influenza A viruses circulating in pigs continue to pose a pandemic…
Ng MK, Mastrokostas PG, Rodriguez AN et al. · 2025 · Journal of craniovertebral junction & spine
Context Semaglutide, a glucagon-like protein-1 receptor agonist used in diabetes and obesity management, has demonstrated perioperative benefits in other surgical populations. However, its role in spine surgery remains unclear. Aims This…
Pilas LB, Gur O, Berger G · 2023 · The Israel Medical Association journal : IMAJ
Background In the past decade, numerous new imaging and laboratory tests have been implemented that significantly contribute to improved medical diagnostic capabilities. However, inappropriate utilization, which occurs on a large scale,…
Jones CMP, Lin CC, Zadro J et al. · 2024 · Brazilian journal of physical therapy
Background The Brief Pain Inventory-Interference Subscale (BPI-IS) is a subscale of the BPI assessment tool developed to rapidly assess the impact of a person's pain on their function. It is uncertain whether it has one or two factors, and…
Lambert SJ, Lunde B, Porsch L et al. · 2024 · Contraception
Objectives This study aimed to compare effectiveness and safety of cervical preparation with osmotic dilators plus same-day misoprostol or overnight mifepristone prior to dilation and evacuation (D&E). Study design We conducted a…
Risi M, Greco G, Masciocchi S et al. · 2024 · Journal of neurology
Background Live cell-based assay (LCBA) is the gold standard for MOG-IgG detection, and fixed CBA (FCBA) is a widely used commercial alternative. Recent criteria attributed a diagnostic value to MOG-IgG titration with both LCBA and FCBA,…
Zheng S, Zhang X, Li W et al. · 2026 · Vaccines
Background: An accurate, sensitive, and robust potency assay is essential for the quality control of mRNA drug substances, which are characterized by complex manufacturing processes, intricate molecular structures, and high susceptibility…
Ilmakunnas I, Sten-Gahmberg S · 2026 · Journal of aging & social policy
Flexible partial retirement schemes are intended to give individuals the opportunity to reduce working hours before moving into full retirement, the expectation being that the reduced workload will contribute to postponed old-age…