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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21277 results · page 242 of 710

Negative / Null Result ReportOpen accessMedicine

Nutrition in early life interacts with genetic risk to influence preadult behaviour in the Raine Study.

Byg LM, Wang CA, Attia J et al. · 2026 · Communications medicine

Background Early life nutrition is associated with child behaviour; however, the interplay with genetic vulnerability is understudied. We hypothesised that psychiatric genetic risk interacted with early nutrition to predict behavioural…

View details →DOI: 10.1038/s43856-025-01339-y
Negative / Null Result ReportOpen accessMedicine

Sign-tracking bias is associated with the inhibition of motor response to appetitive food cues.

Najberg H, Tapparel M, Holmann JN et al. · 2026 · Imaging neuroscience (Cambridge, Mass.)

Response training, such as with the Go/NoGo task, reduces the value of trained items by requiring participants to repeatedly inhibit their responses to appetitive cues that typically elicit approach tendencies. This devaluation is thought…

View details →DOI: 10.1162/imag.a.1118
Negative / Null Result ReportOpen accessMedicine

Trait emotion regulation similarity and well-being.

Eldesouky L, Gross JJ, English T · 2025 · Scientific reports

The ways people manage their emotions (emotion regulation; ER) have been found to affect their own well-being and the well-being of others. In the present research, we extended prior work by examining whether similarity between people's ER…

View details →DOI: 10.1038/s41598-025-08245-2
Negative / Null Result ReportOpen accessMedicine

Experimentally induced sleep restriction relates to less healthy eating behaviors in some adolescents: effects of age, sex, race, weight class, and socioeconomic status.

Hernandez C, Jensen CD, Duraccio KM · 2025 · Sleep advances : a journal of the Sleep Research Society

Study objectives This secondary data analysis study was designed to evaluate demographic and socioeconomic characteristics that may increase the magnitude of the impact of experimentally induced shortened sleep on suboptimal eating…

View details →DOI: 10.1093/sleepadvances/zpaf050
Negative / Null Result ReportMedicine

Impact of acute sleep restriction on cerebrovascular reactivity and neurovascular coupling in young men and women.

McDonald MJ, Marsh ML, Fears SD et al. · 2025 · Journal of applied physiology (Bethesda, Md. : 1985)

Chronic exposure to shortened sleep is associated with an increased risk of Alzheimer's disease and dementia. Previous studies show insufficient (e.g., poor or fragmented) sleep impairs cerebrovascular reactivity to metabolic stress and…

View details →DOI: 10.1152/japplphysiol.00648.2024
Negative / Null Result ReportOpen accessMedicine

Loss of calcium-dependent phospholipase A2 contributes to multi-omic changes in mouse denervated skeletal muscle.

Czyżowska-Froemling A, Xu H, Harold K et al. · 2026 · Physiological reports

Age-related loss of innervation in skeletal muscle is a key driver of sarcopenia. We investigated the role of calcium-dependent phospholipase A 2 (cPLA 2 ) in denervation-atrophy. cPLA 2 mediates the release of polyunsaturated fatty acid…

View details →DOI: 10.14814/phy2.70906
Negative / Null Result ReportOpen accessMedicine

Long-Term Impact of the COVID-19 Pandemic on Diet Quality Among Adults in the Province of Quebec: Longitudinal Analyses of the NutriQuébec Project

Lancup-Gauthier A, Brassard D, Côté M et al. · 2022 · Current developments in nutrition

Objectives While there is evidence that the early lockdown due to COVID-19 pandemic may have had small positive impacts on several populations’ dietary habits, the longer term effects remain largely unknown. The aim of this study was to…

Failed Experiment ReportMedicine

Neural Responses to Auditory Food Stimuli Following Cognitive Behavioral Therapy for Binge-Eating Disorder.

Chao AM, Agarwal K, Zhou Y et al. · 2024 · The International journal of eating disorders

Objective Adults with binge-eating disorder (BED), compared with those without BED, demonstrate higher blood-oxygen-level-dependent (BOLD) response to food cues in reward-related regions of the brain. It is not known whether cognitive…

View details →DOI: 10.1002/eat.24244
Negative / Null Result ReportMedicine

Out-of-home care placement and mortality rate in early adulthood: identifying vulnerable subgroups in a nationwide cohort study.

Sørensen TT, Rod NH, Nguyen TL et al. · 2023 · European journal of epidemiology

Out-of-home care has been linked to excess mortality across the lifespan. We examined whether this association is modified by the age at first out-of-home care placement and the number of placements. In this population-based cohort study,…

View details →DOI: 10.1007/s10654-022-00959-1
Negative / Null Result ReportOpen accessMedicine

Directional deficits in reactive postural control during perturbations among groups of chronic ankle instability, ankle sprain coper, and healthy control.

Kim MJ, Kim S, Kim J et al. · 2025 · Scientific reports

Unanticipated postural control measures may better identify mechanisms of ankle sprains in real-life situations. The purpose of this study was to identify directional deficits in reactive postural control during unanticipated horizontal…

View details →DOI: 10.1038/s41598-025-98913-0
Negative / Null Result ReportOpen accessMedicine

Visual Perception and Fixation Patterns in an Individual with Ventral Simultanagnosia, Integrative Agnosia and Bilateral Visual Field Loss.

Williams I, Phillipou A, Storey E et al. · 2025 · Neurology international

Background/objectives As high-acuity vision is limited to a very small visual angle, examination of a scene requires multiple fixations. Simultanagnosia, a disorder wherein elements of a scene can be perceived correctly but cannot be…

View details →DOI: 10.3390/neurolint17070105
Negative / Null Result ReportMedicine

Common and distinct neural mechanisms of episodic and semantic memory: Evidence from EEG oscillations.

Kesik DB, Şahintürk-Şentürk S, Yıldırım E · 2026 · Biological psychology

It is essential to examine brain structures and processes involved in retrieval tasks in semantic and episodic memory, two key components of the declarative (explicit) memory system, particularly in terms of regional activity differences…

View details →DOI: 10.1016/j.biopsycho.2026.109302
Negative / Null Result ReportMedicine

Using Pharmacy technicians to obtain medication histories for emergency department care among older adults.

Qureshi N, Pevnick JM, Torbati SS et al. · 2026 · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists

Purpose Obtaining accurate medication histories for older adults in the emergency department (ED) is essential but challenging due to operational barriers and incomplete electronic health records (EHRs). We implemented a…

View details →DOI: 10.1093/ajhp/zxag157
Negative / Null Result ReportMedicine

Cannabis Use Disorder and Suicidal Ideation in the United States: Persistent Risk and Stable Trends, 2014-2023.

Oyetunji TP, Chan-Golston AM, Ha S et al. · 2026 · Journal of studies on alcohol and drugs

Objective Amid rising cannabis use, declining perceived harm, and policy liberalization over the past 15 years, we examined whether the association between cannabis use disorder (CUD) and past-year suicidal ideation among U.S. adults…

View details →DOI: 10.15288/jsad.25-00481
Negative / Null Result ReportMedicine

Bidirectional links between sleep and relationship quality: findings from an 8-year longitudinal study of older couples.

Skoblow HF, Tracy EL, Gilligan M · 2026 · The journals of gerontology. Series B, Psychological sciences and social sciences

Objectives The Model of Dynamic Association Between Relationship Functioning and Sleep positions sleep as a fundamentally dyadic and reciprocal process, underscoring the need to study sleep within its relational context and highlighting…

View details →DOI: 10.1093/geronb/gbag067
Negative / Null Result ReportMedicine

Horizontal and vertical distributions of microplastics and their water-sediment partitioning in a macrotidal estuarine embayment: Implications for coastal sequestration potential.

Kim SK, Shin JH, Ji YJ et al. · 2026 · Journal of hazardous materials

Estuarine-coastal regimes are critical links between land and the open ocean, yet their role as microplastics (MPs) sinks and the mechanisms governing MP retention remain poorly constrained. We conducted a coupled water-sediment survey in…

View details →DOI: 10.1016/j.jhazmat.2026.142508
Negative / Null Result Report

Urban-Rural Disparities in the Prevalence, Awareness, Treatment, and Control of Hypertension among Adult Diabetic Patients in Northern State, Sudan: A cross sectional Analytical Community-based Study, 2026

Omer AA, Abdelaziz MO, Bashir RE et al. · 2026 · Preprint

Abstract Background Diabetes and hypertension constitute a dual public health burden, particularly in low-income countries. While urban-rural disparities in healthcare access are well documented, this study aims to compare the prevalence,…

View details →DOI: 10.21203/rs.3.rs-9173542/v1