Negative / Null Result ReportOpen accessOphthalmology
Pear Pongsachareonnont, Nopphawan Uramphorn, Nuchanad Hounnaklang · 2018 · International Journal of Ophthalmology
AIM: To evaluate the association between visual impairment (VI) and mental health or social engagement in older adults living in rural Thailand. METHODS: Data for this cross-sectional study were drawn from a community survey conducted in 2015 in Saraburi Province, Thailand. Participants were 327 adults aged ≥50y. VI was assessed using presenting distance visual acuity. Mental health and social engagement were evaluated in face-to-face interviews using validated questionnaires. After determining the prevalence of VI and relevant sociodemographic characteristics, multivariate regression analysis
View details →DOI: 10.18240/ijo.2018.05.23 Negative / Null Result ReportOpen accessMedicine
Megumi Yokota, Akira Hirasawa, Kazuya Makita et al. · 2015 · Menopause Review
Introduction : Bilateral salpingo-oophorectomy (BSO) is a risk factor for osteoporosis. Previous studies have reported an association between genetic polymorphisms and the risk of developing osteoporosis. However, the relationship between osteoporosis and genetic polymorphisms in Japanese women treated with BSO is not well understood. To improve the quality of life for post-BSO patients, it is important to determine the genetic factors that influence their risk for osteoporosis. The aim of this study was to investigate the association between gene variations of estrogen metabolism-related gene
View details →DOI: 10.5114/pm.2015.54339 Negative / Null Result ReportOpen accessMedicine
Mehmet Yortanlı, Ramazan Köylü, Öznur Köylü et al. · 2025 · Eurasian Journal of Emergency Medicine
Aim: This study aimed to evaluate the diagnostic and prognostic significance of serum beta-trace protein (BTP) levels in patients diagnosed with sepsis in the emergency department. Materials and Methods: This prospective, single-center, observational clinical study was conducted in the emergency department and intensive care unit of a tertiary hospital. A total of 104 sepsis patients and 48 healthy adult volunteers who presented to the emergency department between April 2015 and October 2015 were included. Blood samples were collected on days 1 and 3, and BTP levels were measured using the ELI
View details →DOI: 10.4274/eajem.galenos.2025.37108 Negative / Null Result ReportOpen accessMedicine
Aditi Prayag, Salima Bijapuri, Shweta Bhatbolan et al. · 2025 · Journal of Clinical and Diagnostic Research
Introduction: Breastmilk is recognised as the best infant nutrition, but Exclusive Breastfeeding (EBF) rates remain as low as 63.7% in India and 48% worldwide. One barrier is the development of Musculoskeletal Disorders (MSDs) in postpartum mothers due to a lack of education on proper breastfeeding posture. These factors can impact the quality of the infant’s latch, resulting in early cessation of breastfeeding. Aim: This study aimed to assess the impact of ergonomic breastfeeding on the risk of developing MSD in lactating mothers and infant latch quality. Materials and Methods: The present qu
View details →DOI: 10.7860/jcdr/2025/81001.21464 Negative / Null Result ReportOpen accessMedicine
Yaser Mokhayeri, Seyed Saeed Hashemi-Nazari, Mohammad Ali Mansournia et al. · 2017 · Epidemiology and Health
OBJECTIVES Although the effect of physical activity (PA) on the incidence of atrial fibrillation (AF) has been studied, contradictory results have been reported. Such discrepancies may reflect the different effects of various types of PA upon AF, as well as gender interactions. Therefore, we aimed to evaluate the associations of PA types (total, moderate/vigorous, and intentional), as well as walking pace, with AF risk in men and women. METHODS Using the Multi-Ethnic Study of Atherosclerosis Typical Week Physical Activity Survey, 3 PA measures and walking pace were calculated among 6,487 men a
View details →DOI: 10.4178/epih.e2017024 Negative / Null Result ReportOpen access
Agus Arijanto · 2022 · Cognizance Journal of Multidisciplinary Studies
This study aims to analyze the effect of transformational leadership style and work motivation on employee organizational citizenship behavior (OCB) mediated by employee job satisfaction. The object of the research is employees of PT.…
View details →DOI: 10.47760/cognizance.2022.v02i01.001 Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens
Muller Susan, Bouquot Jerry, Lou Yahuan et al. · 2007 · BMC Cancer
Abstract Background TRAIL plays an important role in host immunosurveillance against tumor progression, as it induces apoptosis of tumor cells but not normal cells, and thus has great therapeutic potential for cancer treatment. TRAIL binds to two cell-death-inducing (DR4 and DR5) and two decoy (DcR1, and DcR2) receptors. Here, we compare the expression levels of TRAIL and its receptors in normal oral mucosa (NOM), oral premalignancies (OPM), and primary and metastatic oral squamous cell carcinomas (OSCC) in order to characterize the changes in their expression patterns during OSCC initiation a
View details →DOI: 10.1186/1471-2407-7-108 Negative / Null Result ReportOpen accessDermatology
Raissa Massaia Londero Chemello, Elsa Regina Justo Giugliani, Renan Rangel Bonamigo et al. · 2011 · Anais Brasileiros de Dermatologia
FUNDAMENTOS: Não há consenso quanto ao efeito do aleitamento materno no desenvolvimento da dermatite atópica. É necessário aprofundar conhecimentos sobre possíveis fatores envolvidos nessa relação, como a influência do aleitamento materno na colonização do paciente atópico pelo Staphylococcus aureus (S. aureus). OBJETIVO: Avaliar uma potencial associação entre aleitamento materno e colonização pelo S. aureus nas crianças atópicas. MÉTODOS: Estudo transversal envolvendo 79 crianças atópicas de 4-24 meses, de ambos os sexos, em acompanhamento no Ambulatório de Dermatologia Sanitária de Porto Ale
View details →DOI: 10.1590/s0365-05962011000300002 Negative / Null Result ReportOpen accessOtorhinolaryngology
Fery Mai Rafanan, Eduard Alfanta, Romulus Roberto Peter Instrella · 2024 · Philippine Journal of Otolaryngology Head and Neck Surgery
Objective: To investigate the association between the time intervals of key clinical time points and tumor progression (increase in clinical staging) in head and neck cancer patients before and during the pandemic. Methods: Design: Retrospective Cohort Study Setting: Tertiary Government Training Hospital Participants: A total of 81 head and neck cancer patients who consulted at the OPD and underwent elective surgery between January 1, 2018, and December 31, 2022, under the Department of Otorhinolaryngology – Head and Neck Surgery of East Avenue Medical Center were included in the study; 40 pat
View details →DOI: 10.32412/pjohns.v39i1.2197 Negative / Null Result ReportOpen accessPsychology
Fahri Sezer, Aytekin Gürtepe · 2025 · BMC Psychology
Abstract The primary aim of this study was to investigate the relationships between attachment, social exclusion, and risky behaviors in adolescents. The sample comprised 463 adolescents, aged 13–18, attending various high schools in Turkey. Data were collected using three instruments: the Parent and Peer Attachment Inventory, the Ostracism (Social Exclusion) Scale for Adolescents, and the Risk Behaviors Scale. The results revealed a moderate negative correlation between attachment to mothers and risky behaviors, while a weaker negative correlation was observed between attachment to fathers an
View details →DOI: 10.1186/s40359-025-02822-w Negative / Null Result ReportOpen accessAgriculture
Nouraldin Moradi, Narges Nazifi, Qodrat Rahimi Miyanaji et al. · 2014 · مجله بیوتکنولوژی کشاورزی
Follicle stimulating hormone receptor (FSHR) and growth differentiation factor 9 (GDF9) both are the most important proteins that affect reproduction process in mammalian. Polymorphism in these genes and their possible relationship with twining trait in Zel (n=150) sheep are investigated in the present study. Blood samples were collected randomly via vein puncture. PCR-RFLP technique for FSHR marker site showed two A and B alleles with the frequency of 93.33 and 6.67 and two genotypes of AA and BB with the frequency of 93.33 and 6.67, respectively. However, the heterozygote AB genotype was not
View details →DOI: 10.22103/jab.2014.1319 Negative / Null Result ReportOpen accessChemical technology
Kyung Won Lee, Min-Sook Kang, Seung Jae Lee et al. · 2023 · Foods
This study aimed to identify major dietary patterns associated with abdominal obesity in middle-aged and older Korean adults. Data from the Korean Genome and Epidemiology Study were used. A total of 48,037 Korean adults aged ≥40 years without abdominal obesity at baseline were followed-up. Dietary assessment was conducted using a validated 106-item food-frequency questionnaire, and dietary patterns were identified using factor analysis. Abdominal obesity was defined as a waist circumference of ≥90 cm for men and ≥85 cm for women, according to the Korean Society for the Study of Obesity. Multiv
View details →DOI: 10.3390/foods12112148 Negative / Null Result ReportOpen accessMedicine
Alexandria Turner, Mieke L van Driel, Ben Mitchell et al. · 2025 · Family Practice
Abstract Background Inappropriate antibiotic prescription for self-limiting respiratory tract infections (RTIs) by general practitioner (GP) registrars (trainees) is less common than by established GPs but still exceeds evidence-based…
View details →DOI: 10.1093/fampra/cmaf005 Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens
Christian Borel, Caroline Even, Christophe Le Tourneau et al. · 2023 · BMJ Oncology
Objective Salivary gland cancers (SGC) are rare cancers with currently no standard treatment for recurrent/metastatic disease. Based on checkpoint inhibitors benefit in a broad range of tumours, NIvolumab in Salivary gland CArcinoma of the Head and Neck (NISCAHN) evaluated nivolumab efficacy in SGC.Methods and analysis In this phase II single-stage Fleming design, patients with SGC with a progressive disease progression within 6 months prior to entering the study, were divided into ACC (adenoid cytic carcinoma) and non-ACC. All received nivolumab for a maximum of 12 months. The primary endpoin
View details →DOI: 10.1136/bmjonc-2023-000065 Negative / Null Result ReportOpen accessMicrobiology
José C. Segovia, Juan C. Ramírez, Paula Río et al. · 2025 · Microbiology Spectrum
ABSTRACT Two strains of the minute virus of mice (MVM) parvovirus (of the species Protoparvovirus rodent1), named i (immunosuppressive) and p (prototype), show disparate tropism and pathogenicity in mice. Unlike the virulent MVMi, the MVMp is attenuated and infection-restricted in primary mouse hematopoietic cells; however, it does infect human transformed, established, and stem cells. We thus seek here a putative MVMp natural tropism to humans compared to MVMi. Infectious purified MVMp virions suppress in vitro the clonogenic potential of human committed (erythroid and myeloid) and primitive
View details →DOI: 10.1128/spectrum.02339-25 Negative / Null Result ReportOpen accessMedicine
Lei Huang, Tong Li, Lei Xu et al. · 2016 · Chinese Medical Journal
Background: There has been no external validation of survival prediction models for severe adult respiratory distress syndrome (ARDS) with extracorporeal membrane oxygenation (ECMO) therapy in China. The aim of study was to compare the performance of multiple models recently developed for patients with ARDS undergoing ECMO based on Chinese single-center data. Methods: A retrospective case study was performed, including twenty-three severe ARDS patients who received ECMO from January 2009 to July 2015. The PRESERVE (Predicting death for severe ARDS on VV-ECMO), ECMOnet, Respiratory Extracorpore
View details →DOI: 10.4103/0366-6999.185871 Methods Dead-EndOpen accessMedicine (General)
Xiaohui Yang, Yue Meng, Huiyan Feng et al. · 2025 · Frontiers in Medicine
BackgroundEndometriosis is a chronic gynecological condition that can result in pelvic pain and infertility, thereby significantly impacting women's reproductive health. Psychological disorders such as anxiety and depression are common in women with endometriosis and can have a detrimental effect on their quality of life. Conventional postoperative care primarily focuses on medical and surgical aspects; however, there is a growing need to address the psychological wellbeing of patients as part of comprehensive postoperative care. Music listening interventions have emerged as a promising adjunc
View details →DOI: 10.3389/fmed.2025.1626575 Abandoned HypothesisOpen accessMedicine
Kathleen F Brookfield, Michael C Cheung, Relin Yang et al. · 2009 · PLoS ONE
OBJECTIVE: Patient chances for cure and palliation for a variety of malignancies may be greatly affected by the care provided by a treating hospital. We sought to determine the effect of volume and teaching status on patient outcomes for five gynecologic malignancies: endometrial, cervical, ovarian and vulvar carcinoma and uterine sarcoma. METHODS: The Florida Cancer Data System dataset was queried for all patients undergoing treatment for gynecologic cancers from 1990-2000. RESULTS: Overall, 48,981 patients with gynecologic malignancies were identified. Endometrial tumors were the most common
View details →DOI: 10.1371/journal.pone.0004049 Negative / Null Result ReportOpen access
Dwi Gemina, Tini Kartini, Pra Gemini · 2021 · JURNAL AKUNIDA
Cooperatives are directed as a collective community effort to increase the level of economic prosperity together. The research objective was to analyze the effect of external capital, business volume and total assets on the residual…
View details →DOI: 10.30997/jakd.v7i2.4283 Negative / Null Result ReportOpen accessMedicine
Zhang J, Liang J, Lv F et al. · 2026 · Practical laboratory medicine
Objective To investigate the distribution characteristics of potential high-risk pathogens for early-onset neonatal infection in maternal vaginal secretions, and to perform a head-to-head comparative evaluation of detection performance for…
View details →DOI: 10.1016/j.plabm.2026.e00542 Negative / Null Result ReportMedicine
Pabarjay M, Azarfarin R, Alizadeh-Ghavidel A et al. · 2026 · BMC anesthesiology
Background Ultrafiltration is integral to cardiopulmonary bypass, yet the optimal replacement fluid for zero-balance ultrafiltration requires further investigation to guide clinical practice. This study aimed to compare the efficacy of…
View details →DOI: 10.1186/s12871-026-03711-4 Negative / Null Result ReportOpen accessMedicine
Meng C, Deng X, Yang Y et al. · 2026 · BMC musculoskeletal disorders
Background There is still debate regarding whether the remnant tendon on the greater tuberosity should be removed during rotator cuff repair (RCR). This study aimed to evaluate whether remnant preservation (RP) in RCR leads to better…
View details →DOI: 10.1186/s12891-026-09785-y Negative / Null Result ReportMedicine
Abd Allah DAE, Abdelfattah AM, Nawar NH et al. · 2026 · The Journal of prosthetic dentistry
Statement of problem The effect of integrating facial scans into digital planning on the accuracy of placement of dental implants and the preplanned interim prosthesis in maxillary complete arch implant rehabilitations has not been clearly…
View details →DOI: 10.1016/j.prosdent.2026.05.052 Negative / Null Result ReportMedicine
Xu Y, Czajkowski M, Hanley N et al. · 2025 · Ecological economics
A large literature in behavioral science suggests that people's emotional condition can have an impact on their choices. We consider how people's emotions affect their stated preferences and willingness to pay for changes in environmental…
Negative / Null Result Report
Koutsonida M, Markozannes G, Kanellopoulou A et al. · 2026 · Preprint
Background: Metabolic syndrome (MetS) has been associated with cognitive decline. Considering its increasing prevalence worldwide, the goal of this study was to evaluate the feasibility and efficacy of a short-term, self-administered…
View details →DOI: 10.64898/2026.06.22.26356249 Negative / Null Result ReportMedicine
Ding L, He M, Zhu Y et al. · 2026 · Scientific reports
Pregnancy emotional states can influence postpartum colostrum delivery, and lactational capacity establishes 1-5 days postpartum. Breast milk production capacity is key to promoting breastfeeding. This study applied positive psychology…
View details →DOI: 10.1038/s41598-026-46318-y Negative / Null Result ReportOpen accessMedicine
Chern CWJ, Cheng LJ, Chiang GSW et al. · 2026 · Age and ageing
Background Physio-cognitive dual-task training (PCDT), combining physical and cognitive tasks, is a promising approach. However, clarity regarding its effectiveness and evidence credibility remains limited. Objective To evaluate PCDT…
View details →DOI: 10.1093/ageing/afag061 Negative / Null Result ReportMedicine
Chandi JK, Nandi K, Biswas RK et al. · 2026 · BMJ case reports
Idiopathic vascular epiretinal membrane (ERM) is a macular disorder which is an extremely rare entity. A hypertensive male in his early 50s presented with complaints of distortion and diminished vision in the left eye. Fundus examination…
View details →DOI: 10.1136/bcr-2025-267668 Negative / Null Result Report
Ali MAA, Zeitoun MM, Ebeid TA et al. · 2026 · Preprint
Abstract This study aims to investigate the roles of adding oleuropein and two types of monosaccharides on the post-thaw bull semen characteristics. Semen was collected from five Brown Swiss bulls twice a week for 16 weeks. Two experiments…
View details →DOI: 10.21203/rs.3.rs-9731141/v1 Negative / Null Result ReportOpen accessMedicine
Shayan SK, Abbood RS, Al-Taie SF et al. · 2026 · Pharmacology research & perspectives
Cardiovascular diseases (CVD) remain to impose a main global burden of morbidity and mortality despite advances in anticipation and treatment. Omega-3 fatty acids, mainly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have…
View details →DOI: 10.1002/prp2.70265 