A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21266 results · page 223 of 709
Li N, Wu C, Cao P et al. · 2023 · Preprint
Abstract Background: Rhodococcus equi is one of the most important causes of zoonotic infections from grazing animals. It poses a particular risk to immunocompromised individuals, including those who are undergoing long-term…
Akbarzadeh G, Abedi P, Jahanfar S et al. · 2024 · Frontiers in medicine
Background Sexual dysfunction is prevalent among breastfeeding women. Objective This study was designed to evaluate the effect of Rose damascene extract on sexual function and anxiety of breastfeeding women. Materials and methods This was…
Nishiofuku H, Mori M, Yokomichi N et al. · 2024 · Journal of palliative medicine
Delirium is a distressing condition in terminally ill cancer patients, often treated with antipsychotics. Administering them orally, subcutaneously, or intravenously can be challenging in severely agitated patients. Transdermal…
Oliver-Pons C, Sala-Vila A, Cofán M et al. · 2024 · Journal of the American Geriatrics Society
Background Nutritional strategies to maintain bone health in aging individuals are of great interest. Given the beneficial nutrient composition of walnuts, rich in alpha-linolenic (the vegetable n-3 fatty acid) and polyphenols, their…
Wang Y, Wang C, Yin S et al. · 2025 · CNS neuroscience & therapeutics
Background Systemic therapeutic options for meningiomas remain limited. Emerging evidence indicates meningiomas harbor an immunosuppressive microenvironment and programmed cell death ligand 1 (PD-L1) expression is significantly upregulated…
Panca M, Serfaty M, Satchell J et al. · 2025 · Preprint
Abstract Background : Crime has significant impact on older victims. High rates of anxiety and depression may be associated with crimes. Aims: This paper aims to evaluate the cost-effectiveness of a Victim Improvement Package (VIP) for the…
Polauke E, Stage Sø J, Carl H et al. · 2024 · Journal of environmental management
Ambitious to fulfill the European Water Framework Directive obligations, the European governments support projects to rehabilitate lakes with poor water quality. However, most lake restorations having relied on biomanipulation by fish…
Li J, Zhou J, Ha Q et al. · 2026 · Frontiers in cardiovascular medicine
Objective Obesity is an independent risk factor for cardiovascular diseases and elevated mortality, yet the underlying mechanisms remain incompletely understood. Impaired endothelium-dependent relaxation is an early manifestation of…
Shankie-Williams K, Day M, Dowland S · 2026 · Biology open
There is a critical need for novel non-hormonal contraceptives. Zinc-based intrauterine devices (IUDs) demonstrate 100% efficacy in rats, yet the mechanism remains unclear. We investigated whether zinc targets sperm, embryos, or the…
Zaidi S, Zoya M, Ishrat M et al. · 2026 · Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
The study aimed to evaluate delays in emergency department (ED) arrival among stroke patients and to identify demographic factors that contribute to these delays. It was a cross-sectional study conducted at the Department of Neurology,…
Rowhani M, Hörmannstorfer-Fessl K, Kastner M et al. · 2026 · Respiratory medicine
Background Dry powder inhalers (DPIs) prescribed for respiratory diseases require patients to generate sufficient peak inspiratory flow (PIF) for optimal drug delivery to the airways. However, information is scarce regarding PIF of asthma…
Moss AS, Nguyen QG, Iyer P · 2026 · Clinical rheumatology
Background Patient education materials are vital to health education and, according to the American Medical Association (AMA), should not be written above a 6th grade reading level (Weiss 2003). We aim to assess American College of…
Carnes N, McAnany J, Khodr Z et al. · 2026 · Journal of attention disorders
Objective Attention-deficit/hyperactivity disorder (ADHD) can potentially disqualify individuals for military service. However, some past research suggests the performance of individuals with ADHD in military service may be comparable to…
Heilmann F, Langsdorf LE, Schubert T · 2026 · Psychological research
This study investigated how stimulus material and effector specificity influence interference control (a form of inhibitory control) in adolescent players. Ninety-one males aged 15-18 years (28 handball players, 34 soccer players, 29…
DeBoest A, Holley C, Hickey M et al. · 2026 · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
Purpose To determine the impact of pharmacist intervention with real-time continuous glucose monitors (rtCGMs) on glycated hemoglobin (HbA1c) levels and the number of pharmacist touchpoints compared to standard of care (SOC). Methods…
Michelutti N, Baud A, Meyer-Jacob C et al. · 2026 · Preprint
Abstract The “top–bottom” approach in paleolimnology provides a rapid means of assessing environmental change by comparing modern surface sediments with deeper intervals assumed to pre-date major anthropogenic disturbances (ca. pre-1880).…
Phan TH, Phan MQ · 2026 · La Clinica terapeutica
Background Residual cardiovascular risk after acute myocardial infarction (AMI) is driven not only by dyslipidemia but also by systemic inflammation. High-sensitivity C-reactive protein (hs-CRP) and low-density lipoprotein cholesterol…
Zhang Z, Luo Z, Lai M et al. · 2026 · Optics express
To address the severe intersymbol interference (ISI) in high-speed optical transmission systems, this paper proposes a memory-augmented neural network equalizer (MANNE). Building upon the architecture of a traditional neural network…
Xiao H, Zeng X, Pang Q et al. · 2026 · Transplant immunology
Background Sodium-glucose cotransporter-2 inhibitors (SGLT2i) yield additional cardiorenal benefits beyond glycemic control. Emerging evidence suggests that SGLT2i have potential benefits in organ transplantation, though causal…
Park M, Park H, Baek IH et al. · 2026 · Journal of patient safety
Objectives Erythropoiesis-stimulating agents (ESAs), classified as long-acting or short-acting, is a primary treatment for anemia in chronic kidney disease and chemotherapy. Given ongoing safety concerns regarding cardiovascular events and…
Tulsian V, Kant R, Patnaik I et al. · 2026 · Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology
Background and objectives Helicobacter pylori infection is highly prevalent globally. Standard bismuth quadruple therapy is commonly used in India, but there are growing concerns regarding the emergence of anti-microbial resistance and…
Hong WJ, Huang JM, Liu YH et al. · 2025 · Aesthetic plastic surgery
Background The postauricular injection technique is a needle-based technique that places soft tissue fillers behind the ears into the supra-periosteal plane of the mastoid process of the temporal bone. The resulting clinical effect pushes…
Morris JS, Rajshekhar S, Gremmo G et al. · 2026 · European journal of obstetrics, gynecology, and reproductive biology
Deep endometriosis (DE) is established to cause chronic pelvic pain (CPP), lower urinary tract symptoms (LUTS) and altered bowel function. Although the aim of surgical excision is often to relieve CPP, evidence suggests it could also…
Sit B, Sanderlin AG, Zhu CY et al. · 2025 · Preprint
Obligate intracellular bacterial pathogens cannot grow extracellularly, a trait that renders them highly understudied, but also endows them with unexpected host dependencies. Here, using the emerging obligate intracellular tickborne…
Reiter T, Dörrler AL, Hasenauer N et al. · 2026 · European journal of nuclear medicine and molecular imaging
Introduction Acute myocardial infarction (AMI) triggers local inflammation in the injured myocardium, followed by a systemic inflammatory response of lymphatic organs. This prospective trial (NCT05519735) focused on molecular imaging of…
Shabbir A, Abbas G, Alharby HF et al. · 2026 · International journal of phytoremediation
Heat stress and soil arsenic (As) contamination are resulting in severe decline in crop production around the world. The present experiment aimed to assess physiological and biochemical changes induced by the combination of As and heat…
Jeneson J, van den Berg-Faay A, Hooijmans M · 2025 · Preprint
We employed interleaved dynamic 1H magnetic resonance imaging (MRI) and 31P MR spectroscopy in combination with arm-cycling to investigate correlations of exercise hyperemia and muscle energetics in the triceps brachii (TB) muscle of the…
Jacobsen P, Cloos L, vanpaemel w et al. · 2025 · Preprint
Affective inertia – the extent to which changes in one’s affective state persist over time – isan important feature of affect dynamics. It is often examined using experience sampling studies thatcapture momentary affect multiple times per…
Son AJ, Rapp E, Wiezorek A et al. · 2026 · JCI insight
Stopping and restarting GLP-1 weight-loss drugs in mice made them less effective over time and increased fat gain compared with continuous treatment.
Cottom JM, Verdoni TJ · 2026 · The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons
Background Total ankle replacement continues to find significantly increased utilization as the technology advances. While there are different systems on the market, most are implanted through an anterior incisional approach just lateral…