Negative / Null Result ReportOpen accessGynecology and obstetrics
Yangyang Zhang, Yang Xu, Jiao Yu et al. · 2023 · Journal of Ovarian Research
Abstract Background A premature luteinizing hormone (LH) surge refers to an endogenous LH peak that occurs before follicle maturation or human chorionic gonadotropin injection in the process of controlled ovarian hyperstimulation. The effect of premature LH surge on pregnancy outcomes in fresh embryo transfer cycles is still controversial. The aim of this study was to explore the effect of a premature LH surge without elevated progesterone levels on the cumulative pregnancy rate (CPR) and cumulative live birth rate (CLBR) of patients during a flexible GnRH antagonist protocol. Methods A total
View details →DOI: 10.1186/s13048-023-01219-w Negative / Null Result ReportOpen accessNeurosciences. Biological psychiatry. Neuropsychiatry
Jia Lu, Yang Chen, Lili Shi et al. · 2023 · BioPsychoSocial Medicine
Abstract Background In Asia, the proportion of patients with irritable bowel syndrome (IBS) with abdominal discomfort alone is significantly higher than that in western countries. The purposes of this study are to understand the cognition of abdominal pain and abdominal discomfort in Chinese patients with IBS and to compare the clinical characteristics of patients with abdominal pain alone and with abdominal discomfort alone. Methods Patients with IBS with diarrhea (IBS-D) who met the Rome III diagnostic criteria and had episodes of at least one day/week were consecutively enrolled. The cognit
View details →DOI: 10.1186/s13030-023-00286-1 Negative / Null Result ReportOpen accessGeriatrics
Hong-Jhe Chen, Hsun Ou, Ru-Yih Chen et al. · 2025 · BMC Geriatrics
Abstract Background This study investigated the relationship between sleep disturbance, obstructive sleep apnea (OSA), and osteoporosis in older adults. Methods This cross-sectional study involved 326 older adults (mean age: 83.46 years) in elder care institutions in Taiwan. The presence of osteoporosis was assessed using dual-energy X-ray absorptiometry, while sleep quality and OSA risk were evaluated using the Pittsburgh Sleep Quality Index and STOP-Bang questionnaire, respectively. Heart rate variability (HRV) was measured to assess autonomic function. Logistic regression models, adjusted f
View details →DOI: 10.1186/s12877-025-06527-y Negative / Null Result ReportOpen accessSurgery
Camila Lopes Cardoso, Osny Ferreira Júnior, Paulo S. Perri de Carvalho et al. · 2011 · Acta Cirúrgica Brasileira
PURPOSE: To evaluate two treatment modalities of dry socket in rats and to discuss the first findings of the molecular analysis in this experimental model. METHODS: 84 rats underwent a tooth extraction were divided in 4 groups: I-uninfected socket (control), II-infected socket without any treatment, III-infected socket treated with irrigation of 2% sodium iodide and 3% hydrogen peroxide solution, IV-infected socket submitted to curettage, irrigation with physiological saline solution and fulfilled with metronidazole paste as base. The groups were subdivided in postoperative sacrifice periods:
View details →DOI: 10.1590/s0102-86502011000500007 Negative / Null Result ReportOpen accessOrthopedic surgery
Min Zou, Xin Duan, Mufan Li et al. · 2023 · Journal of Orthopaedic Surgery and Research
Abstract Background Treating lateral compression type 1 (LC1) pelvic ring injuries in older patients is controversial. This study evaluated surgical treatments combined with ERAS for treating LC1 pelvic fractures in the elderly. Methods In this retrospective study, patients who underwent surgery with INFIX (supra-acetabular spinal pedicle screws, and a subcutaneous connecting rod; the experimental group) or superior pubic ramus cannulated screw (the control group) fixation of LC1 pelvic fracture from January 2019 to January 2022 were reviewed. Injury radiography and computed tomography were pe
View details →DOI: 10.1186/s13018-023-04219-0 Negative / Null Result ReportOpen accessOils, fats, and waxes
孙玉萍，刘启东，杨亚，仇长璐，黄国栋，莫泳红，胡金华 SUN Yuping, LIU Qidong, YANG Ya, QIU Changlu, HUANG Guodong, MO Yonghong, HU Jinhua · 2023 · Zhongguo youzhi
为了对中包装的大豆油棕榈油煎炸专用调和油配方的开发和煎炸稳定性相关理化指标的选择提供参考，分别以一级大豆油、分提18 ℃棕榈油（一次精炼）及同批次的二次精炼18 ℃棕榈油为煎炸油，模拟薯条在180 ℃下高温煎炸32 h，对3种油品在煎炸过程中的酸值、过氧化值、p-茴香胺值、脂肪酸组成、极性组分含量、生育酚含量等理化指标进行了检测，并对18 ℃棕榈油中的风险因子，如PAH4、苯并（a）芘、3-氯丙醇酯（3-MCPDE）、反式脂肪酸含量进行了分析。结果表明：3种油品的酸值、过氧化值在煎炸过程中变化不明显，而p-茴香胺值、脂肪酸组成、极性组分含量在煎炸过程中变化比较明显；3种油品的生育酚氧化速度总体偏差不大；分提18 ℃棕榈油、二次精炼18 ℃棕榈油中的苯并（a）芘、反式脂肪酸含量均随煎炸时间延长呈缓慢升高的趋势；二次精炼18 ℃棕榈油的3-MCPDE在未煎炸时远高于分提18 ℃棕榈油的，3-MCPDE在煎炸初期降解剧烈，最终达到平衡；分提18 ℃棕榈油与二次精炼18 ℃棕榈油在煎炸稳定性方面没有明显区别，二次精炼不仅损失了部分有益的微量营养成分（如生育酚），还伴生出新的风险因子，如增加了3-MCPDE、反式脂肪酸。综上，酸值、过氧化值不能作为评价煎炸稳定性的敏感指标，而p-茴香胺值、脂肪酸组成、极性组分含量可作为敏感指标联合应用于评价煎炸油煎炸稳定性，另外，应倡导适度加工，以降低精炼过
View details →DOI: https://doi.org/10.19902/j.cnki.zgyz.1003-7969.210791 Negative / Null Result ReportOpen accessDiseases of the digestive system. Gastroenterology
Tadataka Takagi, Fumikazu Koyama, Hiroyuki Kuge et al. · 2024 · Journal of the Anus, Rectum and Colon
Objectives: This study aimed to investigate the impact of the COVID-19 pandemic on the examination and treatment of colorectal cancer (CRC) and on the behaviors of patients and practitioners. Methods: This is a retrospective analysis of the CRC patients who presented to our department between April 2019 and March 2021 and underwent surgery. Clinical presentation of CRC and time from symptom onset to medical presentation were compared between the control (April 2019 to March 2020, n=124) and COVID-19 pandemic periods (April 2020 to March 2021, n=111). Results: Two hundred and thirty-five patien
View details →DOI: 10.23922/jarc.2023-034 Negative / Null Result ReportOpen accessEcology
Imed Nouri, Khouloud Chaabane, Rym Bouzaabia · 2026 · Nature Conservation
Immersive virtual reality is increasingly being used as a tool for promoting environmental awareness, particularly to strengthen engagement with nature. However, most research has focused on the short-term effects of a single exposure, neglecting the issue of sustainability and the potential reinforcement of effects through repeated exposure. Furthermore, few studies have examined the role of affective factors such as love and care for nature in this context. The aim of this study was to examine short- and long-term differences in levels of environmental awareness and pro-conservation behavior
View details →DOI: 10.3897/natureconservation.63.176597 Negative / Null Result ReportOpen accessMedicine
Sadan Soyyigit, Onur Baykara, Nur Buyru et al. · 2013 · Medicine Science
Chronic obstructive pulmonary disease (COPD) is a disease which genetic and environmental factors play an important role in COPD development. VDBP (Vitamin D Binding Protein ) gene might be responsible for COPD development. The purpose of this study to investigate the possible effect of VDBP on progression of COPD. We studied VDBP genotypes in 75 COPD patients, 36 smoker healthy subjects and 19 non-smoker healthy subjects with PCR-RFLP method to analyze the association between VDBP and COPD. In our study, the most frequently seen genotype was 1S-2 with a frequency of 32% in COPD group; and 1F-
View details →DOI: 10.5455/medscience.2012.01.8040 Negative / Null Result ReportOpen accessScience
Felix Willmer, Claire Reuter, Stephan Pramsohler et al. · 2023 · Life
Background: Athletes often experience poor sleep quality due to stress, altitude exposure, travel across different time zones, and pre-competition nervousness. Coaches use daytime naps to counteract the negative effects of fragmented nighttime sleep. Napping before competitions has also been used to enhance performance in athletes without sleep problems, with mixed results in previous studies, particularly for endurance performance. Thus, we investigated the effects of napping after partial sleep deprivation (PSD) on endurance performance and wakefulness in athletes. Methods: We recruited 12 h
View details →DOI: 10.3390/life13061414 Negative / Null Result ReportOpen accessPlant culture
Simone Pietro Garofalo, Vincenzo Giannico, Beatriz Lorente et al. · 2024 · Frontiers in Plant Science
IntroductionIn the context of climate change, monitoring the spatial and temporal variability of plant physiological parameters has become increasingly important. Remote spectral imaging and GIS software have shown effectiveness in mapping field variability. Additionally, the application of machine learning techniques, essential for processing large data volumes, has seen a significant rise in agricultural applications. This research was focused on carob tree, a drought-resistant tree crop spread through the Mediterranean basin. The study aimed to develop robust models to predict the net assim
View details →DOI: 10.3389/fpls.2024.1302435 Negative / Null Result ReportOpen accessDentistry
Sara Ordooei Javan, Reza Movahedian, Somayeh Hosseini Tabatabaei · 2025 · Dental Research Journal
Background: During the incremental technique of composite restorations, it is possible to be exposed to contamination of the oral environment. This study aimed to compare the effect of saliva contamination and different methods of saliva decontamination on microshear bond strength within composite surfaces. Materials and Methods: This in vitro study created 24 rectangular XT composite blocks using a silicone mold (24 mm × 10 mm × 10 mm). The blocks were divided into eight groups as follows: Group 1: Control group (without contamination); Group 2: Contaminated with saliva; Group 3: saliva + dri
View details →DOI: 10.4103/drj.drj_736_23 Negative / Null Result ReportOpen accessTherapeutics. Pharmacology
Jiagen Wen, Meizi Zeng, Zhaoqian Liu et al. · 2019 · Journal of Pharmacological Sciences
Metformin is the most widely used drug among type 2 diabetes mellitus patients. However, drug interaction on metformin will influence its glucose-lowering effect or increase its side effect of lactic acidosis. In this study, a randomized, two-stage, crossover study was conducted to unveil the potential drug interaction between metformin and the anti-hypertension drug, telmisartan. Totally, 16 healthy Chinese male volunteers were enrolled. Blood samples from various time-points after drug adminstration were analyzed for metformin quantification. Oral glucose tolerance test (OGTT) was conducted
View details →DOI: 10.1016/j.jphs.2018.11.007 Negative / Null Result ReportOpen accessGynecology and obstetrics
Yahya Irwanto · 2012 · Indonesian Journal of Obstetrics and Gynecology
Objective: To know whether the expression of Fas Ligand has correlation with incidene of metastasis of pelvic lymph node and lymph-vascular stromal invasion (LVSI). Methods: All patients diagnosed of cervical cancer stage IB or IIA who underwent radical hysterectomy in Dr. Cipto Mangunkusumo Central General Hospital from January 2008 until December 2009 were included in analytic cross sectional study. We tested expression of Fas Ligand in cervical cancer specimen by immunohystochemistry with monoclonal antibody. The expression of Fas Ligand was compared between the group of patients with a pos
View details →DOI: 10.32771/inajog.v36i4.325 Negative / Null Result ReportOpen accessScience (General)
Afsoon Motallebi, Mehdi Fathi, Fatemeh Mazhari et al. · 2024 · Heliyon
Background: This randomized clinical trial (RCT) investigated whether hypnosis would lead to favorable outcomes in reducing anxiety, enhancing cooperation, and improving physiological responses in school-aged children undergoing tooth extraction compared to nitrous oxide/oxygen (N2O/O2) and conventional behavior guidance (CBG). Methods: Sixty-six school-aged children (mean age: 7.87 ± 1.18 years) who needed one posterior primary tooth extraction were included. Children with low-to-moderate anxiety were randomly divided into three groups (n = 22 each): hypnosis, N2O/O2, and CBG. Anxiety levels
View details →DOI: 10.1016/j.heliyon.2024.e35223 Negative / Null Result ReportOpen accessMedicine
Joan Hermosura, Everett Lohman, Brenda Bartnik-Olson et al. · 2024 · PLoS ONE
Objectives The main purpose of this research study was to compare mean modified straight-leg raise test (mSLR) and hamstring muscle length (HL) between chronic non-specific low back pain (LBP) and healthy subjects to understand the possibility of neuropathic causes in LBP population as it may impact the diagnosis and treatment of LBP. Another purpose was to compare mean mSLR between those with lumbar nerve root impingement and those without as determine by magnetic resonance imaging (MRI). Methods The design of the study is cross sectional and included 32 subjects with ages ranging from 18-50
View details →DOI: 10.1371/journal.pone.0298257 Negative / Null Result ReportOpen accessDentistry
Sonam Mufti, Sarvagna Mayank Dadawala, Phoram Patel et al. · 2017 · Contemporary Clinical Dentistry
Background: One of the most common aesthetic problem encountered in the field of periodontology is gingival recession, which is, perceived by the patients as increase in length of teeth. The treatment of buccal gingival recession is a common requirement due to aesthetic concern or root sensitivity. This study was planned to evaluate the efficacy of PRF membrane compared to that of CTG in Miller's class I gingival recessions. Materials and Methods: 32 sites with Miller's Class I gingival recessions, out of which 16 sites received PRF (test) and 16 sites received CTG (control). Each patient had
View details →DOI: 10.4103/ccd.ccd_325_17 Negative / Null Result ReportOpen accessDentistry
Huiying Li, Huiying Li, Tong Wang et al. · 2025 · Frontiers in Dental Medicine
BackgroundReattachment of root fragments with appropriate adhesive materials is expected to be the last conservative treatment for preserving teeth with vertical root fractures (VRFs).ObjectiveThis study evaluated the biocompatibility of 4-META/MMA-TBB resin for root repair, compared with iRoot BP Plus, Fuji IX GIC, and Clearfil SA Luting. Fracture resistance and microleakage of the reattached roots were also tested.MethodsThe biocompatibility of set materials was evaluated on L929 fibroblasts. Cell Counting Kit-8 (CCK-8) assay, live/dead cells staining and flow cytometry were used to assess c
View details →DOI: 10.3389/fdmed.2025.1593189 Negative / Null Result ReportOpen accessDiseases of the digestive system. Gastroenterology
Saixin Li, Zheng Wang, Zheng Li et al. · 2024 · BMC Gastroenterology
Abstract Background T-tube cholangiography and choledochoscopy are commonly used techniques for detecting residual bile duct stones after biliary surgery. However, the utility of routine cholangiography before T-tube removal needs further investigation. This study aims to evaluate the diagnostic efficacy of various methods for detecting residual calculi following biliary surgery. Methods We retrospectively analyzed the clinical data of 287 adult patients who underwent common bile duct exploration with T-tube drainage, followed by T-tube cholangiography and choledochoscopy, at the Department of
View details →DOI: 10.1186/s12876-024-03474-7 Negative / Null Result ReportOpen accessEnvironmental sciences
Fahrimal Yudha, Asmilia Nuzul, Aisyah Siti et al. · 2020 · E3S Web of Conferences
As one of the Local wisdom in Aceh, farmer prefers raising polled cow than horned cow for breeding purposes. They believe pole cow is more resilient in harsh conditions and reproductively better than the horned cow. The aim of this study was to evaluate blood profile and blood biochemistry of the aceh polled and horned cow. The blood profile examined includes erythrocyte value, erythrocyte indices MCV (Mean Corpuscular Volume), MCH (Mean Corpuscular Hemoglobin), MCHC (Mean Corpuscular Hemoglobin Concentration), thrombocyte, leukocyte, hematocrit, and hemoglobin, while blood biochemistry includ
View details →DOI: 10.1051/e3sconf/202015101056 Negative / Null Result ReportOpen accessEngineering (General). Civil engineering (General)
Amar Thamir Hamad, Musaab Al-Tamer · 2011 · Tikrit Journal of Engineering Sciences
In this study the characteristics of raw and treated wastewater from Ninava drug factory were evaluated. The results revealed that the strength of raw wastewater can be classified as medium concentrated wastewater with respect to its BOD5 since the average value is 231.7 mg/l. In addition a strong correlations were found between many characteristics of raw waste. The characteristics of produced effluent from waste water treatment plant of the factory were within the Iraqi specification for the disposed wastewater constraints in 1997, where the average is 7.8 for pH, 40mg/l for SS, 2.8 mg/l for
View details →DOI: 10.25130/tjes.18.4.12 Negative / Null Result ReportOpen accessMedicine
Hadi Ghaedi, Siamak Takesh, Ebrahim Banitalebi · 2020 · Journal of Shahrekord University of Medical Sciences
Background and aims: Exercise training is a well-established therapeutic tool for treating type 2 diabetes. The purpose of this study is to examine the beneficial effects of personalized sprint interval training (SIT) and combined aerobic endurance and resistance training (Com) on insulin resistance and glycated hemoglobin A1c (HbA1c) concentration in women with type 2 diabetes. Methods: Fifty-two overweight female type 2 diabetic patients (age 45-60 years and body mass index [BMI] > 30) with HbA1c value of 6.5% or higher and fasting blood glucose (FBG) ≥ 126 mg/dL (7.0 mmol/L) were selected.
View details →DOI: 10.34172/jsums.2020.18 Negative / Null Result ReportOpen accessDentistry
Gustavo Vicentis De Oliveira Fernandes, Nuno Bernardo Malta Santos, Rafael Amorim Cavalcanti De Siqueira et al. · 2021 · Journal of Indian Society of Periodontology
Background: Autologous platelet concentrate (APC)/platelet-rich fibrin (PRF) of second and third generations has increased use in periodontics to optimize wound healing. Few systematic reviews (SRs) have reported improved clinical outcomes, while other studies reported significantly better results for the connective tissue graft (CTG). There is still unclear clinical evidence about APC/PRF use to treat gingival recession (GR) defects. Then, the purpose of this SR was to evaluate the use of APC/PRF membranes (2nd and 3rd generations) in root coverage (RC) procedures and assess its efficacy as a
View details →DOI: 10.4103/jisp.jisp_515_20 Negative / Null Result ReportOpen accessInfectious and parasitic diseases
Chiu Rossa WK, Chim Stephen SC, Wu Alan KL et al. · 2005 · BMC Infectious Diseases
Abstract Background It has been postulated that genetic predisposition may influence the susceptibility to SARS-coronavirus infection and disease outcomes. A recent study has suggested that the deletion allele (D allele) of the angiotensin converting enzyme ( ACE ) gene is associated with hypoxemia in SARS patients. Moreover, the ACE D allele has been shown to be more prevalent in patients suffering from adult respiratory distress syndrome (ARDS) in a previous study. Thus, we have investigated the association between ACE insertion/deletion (I/D) polymorphism and the progression to ARDS or requ
View details →DOI: 10.1186/1471-2334-5-26 Negative / Null Result ReportOpen accessMedicine
Seyed Jalal Hashemi, Hamidreza Shetabi, Shayan Saki et al. · 2018 · مجله دانشکده پزشکی اصفهان
Background: The purpose of this study was to compare the effect of endotracheal intubation in three methods of oral, and nasal with and without the help of Magill forceps, on heart rate and blood pressure in patients undergoing maxillofacial surgery. Methods: In this single-blind randomized clinical trial study, 96 patients who underwent facial and maxillofacial surgery, were randomly divided into three groups of oral, and nasal (with or without the use of Magill forceps) endotracheal intubation. Heart rate and blood pressure were studied in patients before the intubation, and 0, 1, 2, 5, and
View details →DOI: 10.22122/jims.v36i499.10673 Negative / Null Result ReportOpen accessInfectious and parasitic diseases
Yuling Zhang, Xiaowei Chen, Ming Zhou et al. · 2024 · Infectious Diseases and Therapy
Abstract Introduction In this single-center retrospective cohort study, we investigated the efficacy of letermovir in preventing Cytomegalovirus (CMV) infection in patients with aplastic anemia (AA) who have undergone allogeneic hematopoietic stem cell transplantation (allo-HSCT). Methods Based on whether or not letermovir was used for preventing CMV infection, the patients were categorized into two groups: letermovir and control groups. The overall survival (OS) rate and cumulative incidence of CMV infection during the first 100 days after allo-HSCT were evaluated. The study included 21 match
View details →DOI: 10.1007/s40121-024-00917-2 Negative / Null Result ReportOpen accessSports
Farnaz Torabi, Mahmud Sheikh, Elahe Arabameri et al. · 2009 · رشد و یادگیری حرکتی ورزشی
The aim of this study was to compare the effect of audience and music on learning and performance of basketball free throw. Subjects were 36 healthy non-athlete girls (age: 22.8±1.59 years, height: 163.1± 5.63 cm and weight: 54.5±7.06) who were randomly divided into three groups of audience (n=12), music (n=12) and control (n=12). Protocol of acquisition phase included basketball free throw for 6 weeks, 3 sessions per week, and 15 trails each session with the presence of motivational factors in separate groups. Score of free throw test was recorded per session. Then, posttest was carried out a
Negative / Null Result ReportOpen accessNeurosciences. Biological psychiatry. Neuropsychiatry
Mohammadreza Emamhadi, Hamid Behzadnia, Seifollah Jafari et al. · 2019 · Caspian Journal of Neurological Sciences
Background: Postoperative pain is a common phenomenon, and its management affects considerably on the recovery process, and patients’ satisfaction. Apotel and pethidine are two conventional medicines used to relieve pain after operation. Objectives: The present study aimed to compare the effect of intravenous injection of Apotel and intramuscular injection of pethidine in relieving pain after hemilaminectomy. Materials & Methods: In the present cross-sectional study, 150 patients who underwent hemilaminectomy were recruited between May 2015 and November 2015. They were taking either Apotel (n=
Negative / Null Result ReportOpen accessInfectious and parasitic diseases
João Paulo Cola, Thiago Nascimento do Prado, Bárbara Manuella Cardoso Sodré Alves et al. · 2025 · BMC Infectious Diseases
Abstract Background Monotherapy with the drug isoniazid (INH) was for a long time the main therapeutic regimen used for tuberculosis preventive treatment (TPT). Research is progressing into the use of new therapeutic regimens that provide more complete TPT. The objective was to analyze the completion and safety of TPT with the drug INH in the form of 300 mg tablets. Methods Pragmatic, randomized, non-blinded, multicenter clinical trial conducted in Brazil from January 2019 to December 2022. Subjects over the age of 18 years with an indication for TPT was included and those whose index case of
View details →DOI: 10.1186/s12879-025-10678-z Negative / Null Result ReportOpen accessSports medicine
Mark V. Paterno PhD, PT, Staci Thomas MS, Timothy E. Hewett PhD, FACSM et al. · 2017 · Orthopaedic Journal of Sports Medicine
Objectives: The incidence of second anterior cruciate ligament (ACL) injury after ACL reconstruction (ACLR) and return to sport (RTS) in a young, active population is likely between 25-33% with the greatest risk in the first 12 months after RTS. Although the use of allograft tissue in young athletes has been reported to result in increased risk of graft failure, differences in graft and contralateral ACL injury risk between patients who receive a hamstrings (HS) autograft and bone-patellar tendon- bone (BTB) autograft has yet to be reported in a young, athletic population. The tested hypothesi
View details →DOI: 10.1177/2325967117s00301 