A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21697 results · page 213 of 724
Chaudhary, Lammy, Grivas · 2026 · Neurosurgical review
Glioblastoma is an aggressive form of brain cancer and poses a challenge in treatment due to its profound heterogeneity and capacity for extensive infiltration into the brain parenchyma. Research has shown glioblastomas near the ependyma…
Ciacciarelli, Nicolini, Saia et al. · 2026 · Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
Infarct growth rate (IGR) is highly heterogeneous among ischemic stroke patients, reflecting a spectrum of progressor phenotypes with clinical implications. We aim to compare different imaging approaches to investigate stroke progressors…
Serttas, Uysal, Deği̇rmenci̇ et al. · 2026 · Injury
Urinary tract infection(UTI) is a common complication following hip fracture surgery in elderly patients. Urinary catheterization is frequently used to improve patient comfort during prolonged preoperative immobilization; however, its…
Aalibraheem, Lopez-Medina, Chahal et al. · 2026 · Pharmacogenetics and genomics
Drug-induced QT prolongation (diQTP) can lead to rare, but potentially fatal adverse effects of many medications, yet individual susceptibility varies due to both clinical and genetic factors. SDHAF3 p.F53L (rs62624461) is a genetic…
Pjanić, Grivas, Jevtić et al. · 2026 · Studies in health technology and informatics
The relationship between vertebral rotation (VR), curve magnitude, and age in adolescent idiopathic scoliosis (AIS) is not yet fully understood. Although VR represents a defining feature of scoliotic deformity, it remains unclear whether…
Aydilek, Ertaş, Kara et al. · 2026 · Journal of orthopaedic surgery and research
Ballistic lower extremity open fractures represent a distinct subset of high-energy injuries characterized by extensive soft-tissue destruction, contamination, and complex wound biology. Although early soft-tissue reconstruction is widely…
Thompson, Adeoye, Williams et al. · 2026 · Journal of health, population, and nutrition
Rapid urbanisation and occupational demands have contributed to unhealthy dietary habits in Nigeria, particularly among professionals. Male academic professionals may be especially vulnerable to poor eating habits due to demanding…
Aubin, Ilharreborde, Lenke et al. · 2026 · Spine deformity
To investigate how the transverse-plane descriptors and modifiers of the SRS-Lenke-Aubin 3D classification-orientation of the regional plane of deformation (ORPD), apical vertebral rotation (AVR), and apical displacement (3D distance from…
Li, Ling, Chen et al. · 2026 · BMC oral health
This study aims to examine the associations between malocclusion severity, uncertainty stress, and mouth-breathing behavior in adults. In order to clarify how psychological stress may influence oral functional patterns and provide new…
Benattia, Saidi, Gouzi et al. · 2026 · Veterinary parasitology, regional studies and reports
Toxoplasmosis is a parasitic disease affecting both humans and animals and is caused by the protozoan parasite Toxoplasma gondii. In livestock, the infection leads to significant economic losses, mainly due to reproductive disorders such…
Liu, Xu, Zhong et al. · 2026 · Quantitative imaging in medicine and surgery
Intracranial atherosclerosis is the predominant etiology of ischemic stroke in East Asian populations. Atherosclerotic progression frequently involves concomitant vascular remodeling, and stroke risk profiles may vary across distinct…
Çaltek, Yassa, Şahin et al. · 2026 · World journal of surgical oncology
This study aimed to identify the factors predicting postoperative morbidity after cytoreductive surgery in patients with advanced-stage epithelial ovarian cancer, to evaluate the effect of this morbidity on the time to initiation of…
Miedziaszczyk, Ng, Fung et al. · 2026 · BMC nephrology
Cardiovascular disease is the leading cause of death in patients with chronic kidney disease and those on peritoneal dialysis (PD), with insulin resistance contributing significantly to adverse outcomes. This study evaluates the…
Liu, Zhang, Pan et al. · 2026 · BMC psychiatry
The association between long-term use of benzodiazepines (BDZs) and cognitive function in patients with schizophrenia has not been fully characterized. This study aimed to investigate the relationship between long-term BDZs use and…
Peng, Wang, Gong et al. · 2026 · International ophthalmology
To compare the outcomes of conjunctival graft (CAG) versus limbal-conjunctival autograft (LCAG) in preventing recurrence after surgery for recurrent pterygium with intraoperative application of 0.02% mitomycin C(MMC). This prospective…
Haq, Hou, Razaee et al. · 2026 · Journal of family medicine and primary care
The Infant and Child Feeding Index (ICFI) is a comprehensive, age-specific measure that evaluates the overall feeding practices of infants and young children. This study aimed to evaluate the feeding practices of children in Kabul,…
Singson, Takayama, Suyama et al. · 2026 · Ecology and evolution
Halodule uninervis plays a critical role in the seagrass ecosystem because its opportunistic traits facilitate expansion and persistence under changing environmental conditions. Yet the population genetic structure and connectivity of this…
Qu, Jiang · 2026 · Frontiers in endocrinology
The uric acid to HDL-cholesterol ratio (UHR) is a composite marker of metabolic and inflammatory imbalance. Although a previous study in a Japanese health check-up population reported a positive and nonlinear association between UHR and…
Guo, Zhou, Guo et al. · 2026 · Frontiers in public health
To investigate the distribution patterns of physical activity levels, perceptions of physical activity and the social support environment among secondary school students; to examine the associations between students' physical activity…
Ohaku, Murayama, Machida et al. · 2026 · Journal of epidemiology
Dietary diversity is associated with enhanced cognitive function and reduced dementia risk among older adults; however, its relationship with structural brain ageing remains unclear. We examined cross-sectional and longitudinal…
Rocha, Silva, Armstrong et al. · 2026 · Human immunology
A dysregulated inflammatory response is a central mechanism underlying severe COVID-19, with elevated serum IL-6 and TNF-α levels consistently associated with increased disease severity and mortality. Growing evidence indicates that…
Wei, Huang, Huang et al. · 2026 · BMC infectious diseases
Human papillomavirus (HPV) is necessary but not sufficient for cervical carcinogenesis. Human herpesviruses (HHVs) may act as cofactors, yet evidence is inconsistent. We assessed HPV genotypes, HHVs, and their co-detection patterns across…
Heyzer, Low, Tan et al. · 2026 · The Journal of frailty & aging
Dual-task cost (DTC) is the performance decline observed during simultaneous motor and cognitive tasks. It is associated with cognitive and physiological vulnerability. However, it remains unclear how specific frailty dimensions and…
Vu, Nguyen, Nguyen et al. · 2026 · Substance use & misuse
Patient trust in healthcare providers (PTP) is critical for improving treatment adherence and outcomes in substance use disorders. As concurrent opioid and methamphetamine use increasingly complicates methadone maintenance treatment (MMT),…
Kannikeswaran, Sivaswamy, Przyklenk et al. · 2026 · Pediatric neurology
Although not routinely recommended, computed tomography (CT) head are frequently performed in children presenting to emergency department (ED) with seizures. Racial and ethnic disparities have been reported in pediatric ED imaging. Our…
Süren, Nergiz, Topsoy et al. · 2026 · Journal of neuro-oncology
Meningiomas are generally benign; however, they have high recurrence rates. The tumor microenvironment, particularly tumor-associated macrophages (TAMs) may play a role in tumor progression and recurrence. This study aimed to investigate…
Zhao, Zhang · 2026 · Frontiers in nutrition
Primary dysmenorrhea (PD) is highly prevalent among women of reproductive age and imposes a substantial burden on daily functioning and quality of life. Beverage consumption has been suggested as a potential lifestyle factor related to…
Gondode, Duggal, Malviya et al. · 2026 · Disaster medicine and public health preparedness
To assess the current levels of knowledge, attitudes, practices (KAP), and institutional support regarding Chemical, Biological, Radiological, and Nuclear (CBRN) disaster preparedness among anesthesia professionals in India, and to…
Arslan, Şar, Imıl et al. · 2026 · BMC pediatrics
Although psychiatric disorders such as depression and anxiety have been reported to be more common in children with precocious puberty, the psychosocial characteristics of puberty variants remain unclear. This study aimed to investigate…
Khefacha, Ben-Hammamia, Ben Sassi et al. · 2026 · Journal of clinical pharmacology
The relationship between age and isoniazid acetylation phenotype remains insufficiently characterized, particularly in elderly populations, where pharmacokinetic variability and susceptibility to toxicity may be increased. This study aimed…