Negative / Null Result ReportOpen accessDentistry
Zahra Hashemi Ardakani, Rashin Giti, Shima Dabiri et al. · 2021 · Dental Research Journal
Background: The flexural strength (FS) of a denture base material is of great concern, and many approaches have been used to strengthen the denture acrylic resins. The present study aimed to evaluate the effect of high-performance polymer (BioHPP) and metal mesh reinforcement on the FS of a heat-cured poly methyl methacrylate (PMMA) acrylic resin. Materials and Methods: This experimental study was done on 30 rectangular specimens (64 mm × 13 mm × 3 mm) of a heat-cured PMMA resin. The specimens were divided into three groups (n = 10) to be reinforced with either metal mesh or BioHPP mesh; one g
View details →DOI: 10.4103/1735-3327.316647 Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens
Rui ZHENG, Xiaosong QIN, Wenjie LI et al. · 2011 · Chinese Journal of Lung Cancer
Background and objective It has been proven that Src played pivotal roles in carcinogenesis, cancer progression and metastasis. The aim of this study is to explore the roles of Src phosphorylation on lung cancer cells. Methods Western blot and immunoprecipitation was used to detect the expression and phosphorylation of Src in lung cancer cells. MTT and Boyden chamber assay was used to examine the effects of inhibition of Src phosphorylation on proliferation and invasion of lung cancer cells in vitro, respectively. Results pp60src was expressed in all lung cancer cell lines in this study. All 5
Negative / Null Result ReportOpen accessFinance
Cindy Maycherles, Moh Muslikh · 2021 · Keunis
The purposes of this research are to analyze and obtain empirical evidence on the effect of usefulness perception, ease perception, and risk perception toward the use of BRI Internet banking in (Politeknik Negeri Semarang) Polines students both simultaneously and partially. The population of this research was Polines students of all departments from 2017 to 2019 as customers of BRI Internet banking users with a sample of 87 respondents. The research used primary and secondary data. The data analysis model uses the Multiple Linear Regression Analysis Model while the data analysis technique uses
View details →DOI: 10.32497/keunis.v9i1.2167 Negative / Null Result ReportOpen accessTherapeutics. Pharmacology
M Dadvand Sarab, H Naghdi Badi, M Nasri et al. · 2008 · Journal of Medicinal Plants
Background: Basil (Ocimum basilicum L.) is a valuable medicinal and aromatic plant which is cultivated throughout the world. Therefore, it is necessary to determine effect of important agronomical factors on quality and quantity of its volatile oil. Objective: To determine plant density and nitrogen fertilization effects on quality and quantity yield of basil. Method: This study was done in Research farm of ACECR, Institute of Medicinal Plants & Natural Products Research in 2006 on the base of factorial experiment in randomized complete block design with four replications. All possible combina
Negative / Null Result ReportOpen accessTherapeutics. Pharmacology
Alan J. Weaver, Timothy R. Borgogna, Galen O’Shea-Stone et al. · 2022 · Antibiotics
The rise in bacterial resistance to common antibiotics has raised an increased need for alternative treatment strategies. The natural antibacterial product, 18β-glycyrrhetinic acid (GRA) has shown efficacy against community-associated methicillin-resistant Staphylococcus aureus (MRSA), although its interactions against planktonic and biofilm modes of growth remain poorly understood. This investigation utilized biochemical and metabolic approaches to further elucidate the effects of GRA on MRSA. Prolonged exposure of planktonic MRSA cell cultures to GRA resulted in increased production of staph
View details →DOI: 10.3390/antibiotics11060781 Negative / Null Result ReportOpen accessPublic aspects of medicine
Rob Horne, Caroline Sabin, Trudie Chalder et al. · 2025 · Programme Grants for Applied Research
Background Antiretroviral therapy has transformed human immunodeficiency virus infection intoa chronic condition associated with normal life expectancy. In the United Kingdom, the uptake of antiretroviral therapy is generally high, but a delay in starting antiretroviral therapy and non-adherence compromise the health and well-being of people living with human immunodeficiency virus, increase the risk of transmission of human immunodeficiency virus and increase National Health Service costs. Objectives The overall aim was to improve antiretroviral therapy uptake and adherence by addressing perc
View details →DOI: 10.3310/kppw8401 Negative / Null Result ReportOpen accessScience (General)
Ayodele Owonubi, Favour Kenneth Chiwendu · 2022 · UMYU Scientifica Journal
The objectives of this research were to investigate the nature of pH buffer capacity and evaluate its association selected soil characteristics the study area. Soil samples from ten profile pits from within the study area were collected from genetic horizons. Soil samples were tested in the laboratory for electrical conductivity and pH buffer capacity using standard procedures. Soil data were analyzed using descriptive statistics. One-way analysis of variance and correlation analysis were applied to determine effects and relationships of selected soil properties with soil pH buffer capacity. T
View details →DOI: 10.56919/usci.1222.006 Negative / Null Result ReportOpen accessTechnology
Domagoj Nakić, Katarina Licht, Hana Posavčić et al. · 2025 · Results in Engineering
Increasing amounts of sewage sludge (SS) and phosphorus-induced eutrophication are major global issues, and this study addresses both under a unified approach, by exploring the potential of biochar derived from SS gasification in an experimental plant as an efficient adsorbent for phosphate removal in synthetic wastewater. The key innovation involves the use of a novel biochar, generated as a byproduct of an innovative gasification process, without any additional pretreatment. This approach could help reduce both environmental and economic burdens in potential real-world applications. Pristine
View details →DOI: 10.1016/j.rineng.2025.106077 Negative / Null Result ReportOpen accessAgriculture (General)
A. S. Abdulrhman, Sh. M. M. Al-Atrushy · 2024 · The Iraqi Journal of Agricultural science
This investigation was aimed to study the effect of soil application of Bio health and foliar application with Tecamin max and Benzyl adenine on growth characteristic of sweet orange (Citrus sinensis L.) seedlings during two successive seasons (2020 and 2021). Bio health was added with three concentrations (0, 6 and 12 g.L-1) to the soil and foliar application of Tecamin max with three concentration (0, 5 and 10 ml.L-1), Benzyl adenine with three concentration (0, 100 and 200 mg. L-1) on the sweet orange seedlings which were brought from private nursery in Duhok city and have two- years old an
View details →DOI: 10.36103/w0z2q378 Negative / Null Result ReportOpen accessPsychiatry
Roxoliana Tsisar, Kristen E. Zentner, Katherine Shettell et al. · 2026 · Frontiers in Psychiatry
BackgroundPsychoeducation for families of young adults with psychosis is an evidence-based intervention that alleviates carer burden. The implementation of programming is limited, leaving family carers shouldering a heavy burden without appropriate support.ObjectiveThis pre-post longitudinal pilot study evaluated the preliminary outcomes of a psychoeducational group intervention for family carers of young adults with psychosis, aimed at building skills and reducing carer burden to support recovery in their loved ones.MethodsThe intervention, co-developed and co-facilitated by healthcare profes
View details →DOI: 10.3389/fpsyt.2026.1724396 Negative / Null Result ReportOpen accessTherapeutics. Pharmacology
Joanna Hajduk, Cyrill Brunner, Sebastian Malik et al. · 2020 · mAbs
Minor changes in the quality of biologically manufactured monoclonal antibodies (mAbs) can affect their bioactivity and efficacy. One of the most important variations concerns the N-glycosylation pattern, which directly affects an anti-tumor mechanism called antibody-dependent cell-meditated cytotoxicity (ADCC). Thus, careful engineering of mAbs is expected to enhance both protein-receptor binding and ADCC. The specific aim of this study is to evaluate the influence of terminal carbohydrates within the Fc region on the interaction with the FcγRIIIa/CD16a receptor in native and label-free condi
View details →DOI: 10.1080/19420862.2020.1736975 Negative / Null Result ReportOpen accessMedicine (General)
Sepide Ghasemian, Zahra Hojjati Zidashti · 2018 · Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum
Background and Objectives: Iron can play an important role in exercise performance of women. The purpose of the present research was to determine the effects of combined exercise training and Feroglobin supplementation on serum iron and lipid profile in Women with iron deficiency anemia. Methods: In this study, 36 trained females with iron deficiency anemia (mean age, 26.8±6.3 years and body mass index, 19.55±4.4kg/m2) of Lahijan city, were selected as subjects and randomly divided into three groups of supplement+combined training, placebo+combined training, and control. Iron lev
Negative / Null Result ReportOpen accessAgriculture (General)
Eleftheria Bempelou, Kyriaki Varikou, Antonios Nikolakakis et al. · 2026 · Agriculture
In Greece, the protection of olive orchards against the olive fruit fly ( Bactrocera oleae ), the most serious pest of olive fruits, is implemented through a national control program. This program is implemented by the Ministry of Rural Development and Food in co-operation with various public and private organizations. A new approach followed for this goal is the use of insecticide spray solutions combined with trophic attractant to attract and kill the olive fruit fly. In the present study, a method for the determination of the major insecticides, lambda-cyhalothrin and Spinosad, in their spr
View details →DOI: 10.3390/agriculture16090957 Negative / Null Result ReportOpen accessTherapeutics. Pharmacology
Wang J, Lu S, Zhang C et al. · 2025 · Drug Design, Development and Therapy
Jinglong Wang, Shijia Lu, Chenxiao Zhang, Junjie Wang, Huiru Wu, Guofei Li Department of Pharmacy, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, People’s Republic of ChinaCorrespondence: Guofei Li, Department of Pharmacy, Shengjing Hospital of China Medical University, No. 36, Sanhao Street, Shenyang, 110004, People’s Republic of China, Tel/Fax +86-24-23925108, Email sylgf2009@163.comPropose: The co-treatment of ulcerative colitis with berberine hydrochloride (BBR), the Janus kinase(JAK) inhibitor Tofacitinib (TOFA), and Fligotinib (FIGA) is feasible and sophisti
Negative / Null Result ReportOpen accessPhysiology
Lin Chang, Silin Fu, Jianghua Li et al. · 2022 · Frontiers in Physiology
Background: Knee injury is common in half-marathon runners, however, the effect of compression running pants on fatigue and knee proprioception remains unclear.Objectives: The study aims to investigate whether wearing compression running pants (CRP) and treadmill running stages affect knee proprioception and fatigue-related physiological responses during half-marathon running.Methods: Eighteen half-marathon runners completed two self-paced 21 km treadmill running trials, once wearing CRP and once wearing loose running shorts (LRS). For each 21 km run, RPE, heart rate, blood lactic acid, and kn
View details →DOI: 10.3389/fphys.2022.1035424 Negative / Null Result ReportOpen accessMedicine
Galiya Iskakova, Bauyrzhan Iztayev, Auyelbek Iztayev et al. · 2025 · Scientific Reports
Abstract The quality of food products and a balanced diet play a key role in maintaining health and improving the quality of life. Due to the high popularity of pasta, a promising direction is the development of recipes that include whole grain flour, carrot powder and ion-ozonated water, which increase the nutritional value of the product and improve its chemical composition. The aim of this study was to optimise the technological modes of production of durum wheat pasta using carrot powder and ion-ozonated water to minimise the loss of dry matter (DM) during cooking and increase the protein
View details →DOI: 10.1038/s41598-025-28027-0 Negative / Null Result ReportOpen accessBibliography. Library science. Information resources
WANG Weizheng, QIAO Hong, LI Xiaojun, WANG Jingjing · 2024 · Nongye tushu qingbao xuebao
[Purpose/Significance] Generative artificial intelligence (AI) technology has been widely used in many fields, and the application of this technology has become popular among researchers. However, there are few studies on the willingness of researchers willingness to accept generative AI. This leads to an insufficient understanding of the psychological mechanism, cognitive process and behavioral pattern of users' acceptance of generative AI, which limits the ability of theoretical innovation and practical exploration in user information behavior. This study focuses on researchers acceptance of
View details →DOI: 10.13998/j.cnki.issn1002-1248.24-0076 Negative / Null Result Report
Michael P Thompson, Ilana Graetz, Naleef Fareed et al. · 2017 · Circulation: Cardiovascular Quality and Outcomes
Objective: With the goal of improving healthcare quality, Medicare has implemented a series of pay-for-performance initiatives and allocated substantial financial resources to promote meaningful use of electronic health records (EHRs). The…
View details →DOI: 10.1161/circoutcomes.10.suppl_3.028 Negative / Null Result Report
Sally Caine, Mariam Alaverdashvili, Frederick Colbourne et al. · 2024 · PLOS ONE
Malnutrition after stroke may lessen the beneficial effects of rehabilitation on motor recovery through influences on both brain and skeletal muscle. Enriched rehabilitation (ER), a combination of environmental enrichment and forelimb…
View details →DOI: 10.1371/journal.pone.0302008 Negative / Null Result Report
Abigail Silva, Arielle Guzman, Charlotte Picard et al. · 2020 · Cancer Epidemiology, Biomarkers & Prevention
Abstract Background: Through its various provisions, the Patient Protection and Affordable Care Act (ACA) has the potential to increase access to cancer care, particularly among the most vulnerable, and reduce disparities in cancer care…
View details →DOI: 10.1158/1538-7755.disp18-b076 Negative / Null Result Report
Siobhan Dickinson, Maryam Naghsh‐Nejad, Kees Van Gool et al. · 2026 · Australian Economic Review
ABSTRACT Research Question/Issue This study examines the impact of the Chronic Disease Dental Scheme (CDDS), introduced in 2007 to provide subsidised dental care for people with chronic conditions. Specifically, it asks whether the CDDS…
View details →DOI: 10.1111/1467-8462.70058 Negative / Null Result Report
Hugh Adler, Kwong Tsang, Michael Abouyannis et al. · 2024 · Journal of Healthcare Simulation
Introduction: The Centre for Snakebite Research & Interventions at the Liverpool School of Tropical Medicine (LSTM) houses >150 venomous snakes. This includes the black mamba (Dendroaspis polylepis) which can cause life-threatening…
View details →DOI: 10.54531/zliz6918 Negative / Null Result Report
K Hirono, K Tsuboi, H Nakaoka et al. · 2025 · European Heart Journal
Abstract Background Dilated cardiomyopathy (DCM) is a progressive myocardial disorder with significant morbidity in children. Although pathogenic gene variants are detected in approximately 30–40% of DCM cases, the impact of sarcomere gene…
View details →DOI: 10.1093/eurheartj/ehaf784.2664 Negative / Null Result Report
Yanbin Shen, Sung Woo Kim, Hans H. Stein et al. · 2025 · Frontiers in Animal Science
Three experiments evaluated the effects of a novel milk ingredient blend (FXP) in phase 1 and 2 nursery pig diets on growth performance, diarrhea score, and survival. In Experiment 1, pigs were fed a 3-phase nursery regimen, with phases 1,…
View details →DOI: 10.3389/fanim.2025.1648283 Negative / Null Result Report
Hadi Praseno, Kumara Adji Kusuma, Rifdah Abadiyah et al. · 2024 · Academia Open
This study examines the productivity differences between disabled and non-disabled workers at PT. United Pharmatic Indonesia. Using a quantitative approach, data were collected from 120 employees in the production department through…
View details →DOI: 10.21070/acopen.9.2024.7929 Negative / Null Result Report
Nativ Henkin, Ifat Karilker, Sergio L. Kobal et al. · 2023 · Journal of Clinical Medicine
Echocardiographic stress tests are often used to evaluate patients who complain of chest pain. However, some patients fail to reach the target heart rate required for the test to be conclusive (usually defined as 85% of the predicted…
View details →DOI: 10.3390/jcm12144832 Negative / Null Result ReportOpen accessComputer Science
Anatoly A. Krasnovsky · 2025 · arXiv
While distributed tracing and chaos engineering are becoming standard for microservices, resilience models remain largely manual and bespoke. We revisit a trace-discovered connectivity model that derives a service dependency graph from traces and uses Monte Carlo simulation to estimate endpoint availability under fail-stop service failures. Compared to earlier work, we (i) derive the graph directly from raw OpenTelemetry traces, (ii) attach endpoint-specific success predicates, and (iii) add a simple asynchronous semantics that treats Kafka edges as non-blocking for immediate HTTP success. We
Negative / Null Result ReportOpen accessComputer Science
Jun Ye · 2026 · arXiv
Decoherence in superconducting qubits arises from both multilevel dynamics and structured environmental noise, yet perturbative models cannot capture all resulting signatures. Here, EmuPlat couples instruction-set-architecture-level waveform generation to the hierarchical equations of motion HEOM under $1/f$ non-Markovian pure dephasing. In the resulting non-perturbative regime -- where filter-function predictions become quantitatively uninformative -- CPMG scaling of a three-level superconducting transmon yields one calibration result, two physical findings, and one structural null. Y-CPMG ex
Negative / Null Result ReportOpen accessPhysics
A. T. Deller, J. P. W. Verbiest, S. J. Tingay et al. · 2008 · arXiv
Using the recently upgraded Long Baseline Array, we have measured the trigonometric parallax of PSR J0437-4715 to better than 1% precision, the most precise pulsar distance determination made to date. Comparing this VLBI distance measurement to the kinematic distance obtained from pulsar timing, which is calculated from the pulsar's proper motion and apparent rate of change of orbital period, gives a precise limit on the unmodeled relative acceleration between the Solar System and PSR J0437-4715, which can be used in a variety of applications. Firstly, it shows that Newton's gravitational cons
Negative / Null Result ReportOpen accessPhysics
Hao Wei, Minzi Feng · 2019 · arXiv
LIGO/Virgo S190814bv is the first high-probability neutron star - black hole (NSBH) merger candidate, whose gravitational waves (GWs) triggered LIGO/Virgo detectors at 21:10:39.012957 UT, 14 August 2019. It has a probability $>99\%$ of being an NSBH merger, with a low false alarm rate (FAR) of 1 per 1.559e+25 years. For an NSBH merger, electromagnetic counterparts (especially short gamma-ray bursts (GRBs)) are generally expected. However, no electromagnetic counterpart has been found in the extensive follow-up observing campaign. In the present work, we propose a novel explanation to this null
