e-ISSN: Pending
Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21697 results · page 201 of 724

Negative / Null Result Report

Maxillary Reconstruction in a Low to Middle Income Country: Institutional Experience Using Fibula Free Flap and Obturator Rehabilitation

Barakat KI, Zaki MH, Elnour MM · 2026 · Preprint

Introduction: Reconstruction of maxillary defects remains challenging because of the complex functional and aesthetic roles of the midface. Although both prosthetic obturation and microvascular reconstruction are established options,…

View details →DOI: 10.20944/preprints202606.0388.v1
Negative / Null Result ReportMedicine

Assessment of psychological and physiological responses to auditory and visual stimuli during recovery from acute stress induction.

Snyder EM, Son YJ, Li L et al. · 2026 · Physiology international

Workplace stress is one of the main sources of stress for adults, although physiological and cognitive factors may impact each person's stress response. Numerous studies have shown heart rate, heart rate variability, neural activity, and…

View details →DOI: 10.1556/2060.2026.00801
Negative / Null Result ReportMedicine

Impact of a multidisciplinary care pathway on follow-up and emergency department utilisation in paediatric musculoskeletal infections.

Bouchard M, Galán-Olleros M, Ng K et al. · 2026 · European journal of pediatrics

To evaluate whether implementation of a multidisciplinary care pathway was associated with changes in unplanned emergency department (ED) visits in children with musculoskeletal infections, and to assess its impact on readmissions,…

View details →DOI: 10.1007/s00431-026-06828-3
Negative / Null Result ReportMedicine

Key factors in the diagnosis of sesame allergy in children.

Hismiogullari A, Sancakli O, Ocak M et al. · 2026 · Allergy and asthma proceedings

Background: Sesame allergy (SA) is diagnostically challenging in childhood, and data on its natural course and clinical nonreactivity development are limited. Although oral food challenge (OFC) remains the diagnostic criterion standard,…

View details →DOI: 10.2500/aap.2026.47.260041
Negative / Null Result ReportMedicine

Comparison between drug-eluting bead transarterial chemoembolization versus conventional TACE in elderly patients with colorectal cancer liver metastases: a cohort study.

Tian L, Hu B, Song M et al. · 2026 · Frontiers in oncology

Background Drug-eluting bead (DEB) transarterial chemoembolization (TACE) possesses several advantages over conventional TACE (cTACE) such as higher intratumor drug concentration and lower systemic toxicity, which has been widely applied…

View details →DOI: 10.3389/fonc.2026.1785622
Negative / Null Result ReportMedicine

Lineage-specific selection signals in the Growth arrest-specific protein 8 (GAS8) domain protein of Trypanosoma melophagium.

Das A, Ghosh A, Pal S et al. · 2026 · Scientific reports

The Growth arrest-specific protein 8 (GAS8) domain-containing gene family (Orthogroup 6127at5690) is a highly conserved, single-copy orthologous group in the Trypanosoma taxa retained for codon-based evolutionary analysis (10 validated…

View details →DOI: 10.1038/s41598-026-56233-x
Negative / Null Result Report

HCC within LR-M on CEUS LI-RADS: Analysis of Washout Timing & Intensity

Samuel AS, Qiao A, Merrill CD et al. · 2026 · Preprint

Abstract Purpose: LR-M nodules > 1cm, are probably or definitely malignant, but not specific for hepatocellular carcinoma (HCC). HCC is found within LR-M category in 44%. We identify CEUS imaging features within the LR-M category…

View details →DOI: 10.21203/rs.3.rs-9596403/v1
Negative / Null Result ReportOpen accessMedicine

Thyroid Function Tests and Serum Amylase Levels in Chronic Kidney Disease: A Cross-Sectional Study Correlating Biochemical Changes With Disease Severity at a Tertiary Care Centre in India.

Sharma P, Samaria A, Tak H et al. · 2026 · Cureus

Background Chronic kidney disease (CKD) represents a major and growing health concern in both global and Indian populations. In addition to progressive renal dysfunction, CKD is frequently accompanied by metabolic and endocrine…

View details →DOI: 10.7759/cureus.104974
Negative / Null Result ReportMedicine

Association between body mass index and high grade cervical intraepithelial neoplasia (CIN 2/3) in a dysplasia referral population.

F G, J H, L SJ et al. · 2026 · Cancer treatment and research communications

Background Obesity is increasingly recognized as a risk factor for several malignancies, including cervical cancer. Women with obesity participate less frequently in screening and may have higher rates of unsatisfactory cytology,…

View details →DOI: 10.1016/j.ctarc.2026.101279
Negative / Null Result ReportMedicine

Aqueous Humor Angiotensin-Converting Enzyme and TGF-β1 Levels in Proliferative Vitreoretinopathy: A Prospective Clinical Study.

Koçak N, Özdemir A, Esenkaya M et al. · 2026 · Retina (Philadelphia, Pa.)

Purpose To evaluate plasma and aqueous humor angiotensin-converting enzyme (ACE) and transforming growth factor-β1 (TGFβ1) levels in patients with proliferative vitreoretinopathy (PVR) secondary to rhegmatogenous retinal detachment (RRD).…

View details →DOI: 10.1097/iae.0000000000004885
Negative / Null Result ReportMedicine

Cardiac Computed Tomography-Guided Procedural Planning for Percutaneous Mitral Paravalvular Leak Closure: Impact on Crossing Time.

Vella C, Romano V, Ricchetti G et al. · 2026 · The Canadian journal of cardiology

Mitral paravalvular leaks (PVLs) are a recognized complication of prosthetic valve implantation and may cause heart failure or hemolysis, often requiring percutaneous closure in patients at high surgical risk. Although transesophageal…

View details →DOI: 10.1016/j.cjca.2026.06.021
Negative / Null Result ReportMedicine

Skeletal muscle status and malnutrition as predictors of short-term radiotherapy response and oral mucositis in head and neck cancer.

Zhang H, Hu X, Zhao J et al. · 2026 · Precision radiation oncology

Objective This study aimed to investigate whether baseline skeletal muscle status and malnutrition in patients with locally advanced head and neck cancer (HNC) are associated with short-term treatment outcomes and acute radiation oral…

View details →DOI: 10.1002/pro6.70072
Negative / Null Result Report

Comparative Analysis of Lesion Detection and Uptake Characteristics of 68Ga-FAPI PET/CT versus 18F-FDG PET/CT in Gastric Cancer: A Preliminary Translational Study

KALENDER E, YILDIRIM EE, YERDEŞ E et al. · 2026 · Preprint

Abstract Purpose This study aimed to compare lesion detection and uptake characteristics of 68 Ga-FAPI PET/CT and 18 F-FDG PET/CT in patients undergoing imaging for gastric cancer (GC) staging. Methods A total of 24 patients with…

View details →DOI: 10.21203/rs.3.rs-9357738/v1
Negative / Null Result ReportMedicine

Clinical course after cardiac resynchronization therapy in transthyretin amyloid cardiomyopathy receiving disease-modifying therapy.

Yamauchi S, Kondo H, Mitarai K et al. · 2026 · Heart and vessels

Background The clinical course of patients with transthyretin amyloid cardiomyopathy (ATTR-CM) undergoing cardiac resynchronization therapy (CRT) remains insufficiently characterized, particularly in the era of disease-modifying therapy…

View details →DOI: 10.1007/s00380-026-02710-2
Negative / Null Result ReportOpen accessMedicine

Comparison of Hook Fixation and Vertebroplasty for Prevention of Proximal Junctional Failure: A Retrospective Cohort Study.

Cho ST, Cho JH, Lee DH et al. · 2026 · Global spine journal

Study DesignRetrospective cohort study.ObjectiveTo compare the association of vertebroplasty and hook fixation at the uppermost instrumented vertebra (UIV) with proximal junctional failure (PJF) after long-segment fusion for degenerative…

View details →DOI: 10.1177/21925682261449174
Negative / Null Result ReportMedicine

Has the Expected Shift in HIV-Related Cancers Occurred? Findings from a Long-Term HIV Cohort in Turkey.

Yılmaz Nakir İ, Özçelik MN, Karaduman RG et al. · 2026 · Journal of clinical medicine

Background/Objectives : Despite widespread antiretroviral therapy (ART) use, whether the expected transition from AIDS-defining to non-AIDS-defining cancers has occurred in settings with persistent late HIV presentation remains unclear. We…

View details →DOI: 10.3390/jcm15124818
Negative / Null Result ReportMedicine

Boric acid Attenuates premature ovarian insufficiency by Modulating oxidative stress in a Cyclophosphamide-Induced rat model.

Ozcakar TG, Kender Erturk N, Onguncan O et al. · 2026 · European journal of obstetrics, gynecology, and reproductive biology

Aim This study aimed to investigate whether boric acid (BA) exerts potential protective effects against cyclophosphamide (CYC)-induced premature ovarian insufficiency (POI) in rats through modulation of oxidative stress and preservation of…

View details →DOI: 10.1016/j.ejogrb.2026.115268
Negative / Null Result ReportMedicine

Effect of a goal-directed sedation nursing intervention bundle on comfort and compliance in children undergoing bronchoalveolar lavage under topical anesthesia with procedural sedation: a randomized controlled trial.

Luo X, Zhang H · 2026 · Frontiers in medicine

Objective To assess the impacts of goal-directed sedation nursing intervention on comfort and compliance in children undergoing bronchoalveolar lavage (BAL) under topical anesthesia with procedural sedation. Methods A total of 168 children…

View details →DOI: 10.3389/fmed.2026.1852309
Negative / Null Result ReportMedicine

Comparison of Dacryoendoscopy-Aided Silicone Tube Intubation and Endoscopic Dacryocystorhinostomy for Complete Nasolacrimal Duct Obstruction.

Yoon Y, Yoon JS, Ko J · 2026 · Korean journal of ophthalmology : KJO

Purpose To compare the surgical outcomes of dacryoendoscopy-aided silicone tube intubation (STI) and endoscopic dacryocystorhinostomy (endo-DCR) for complete nasolacrimal duct obstruction (NLDO), and to identify factors associated with…

View details →DOI: 10.3341/kjo.2026.0020
Negative / Null Result ReportMedicine

Visual and refractive outcomes of small incision lenticule extraction planned with a VISULYZE-generated nomogram for myopia and astigmatism: a retrospective comparative study.

Lin Y, Wei X, Su H et al. · 2026 · BMC ophthalmology

Purpose Small-incision lenticule extraction (SMILE) is a widely used procedure for correcting myopia and myopic astigmatism. However, variability in refractive outcomes, particularly astigmatic correction, remains a concern. This study…

View details →DOI: 10.1186/s12886-026-04945-z
Negative / Null Result ReportOpen accessMedicine

Integrated Ferroptosis and Immune Features Are Associated With Overall Survival in Bladder Urothelial Carcinoma: A TCGA-Based Analysis.

Zhang L, Sheng Z · 2026 · Cancer informatics

Objectives To investigate the prognostic value of ferroptosis-related and immune-related transcriptional features in bladder urothelial carcinoma (BUC) and to evaluate whether their integration provides incremental prognostic information…

View details →DOI: 10.1177/11769351261453955