Negative / Null Result Report
Homann LA, Jahed M, Barense M · 2025 · Preprint
Retrieval practice—actively recalling information—is an established memory-strengthening technique. However, understanding how retrieval transforms memory requires examining its effects on memories that evolve across multiple episodic and…
View details →DOI: 10.31234/osf.io/923rj_v1 Negative / Null Result Report
Homann LA, Jahed M, Barense M · 2025 · Preprint
Retrieval practice—actively recalling information—is an established memory-strengthening technique. However, understanding how retrieval transforms memory requires examining its effects on memories that evolve across multiple episodic and…
View details →DOI: 10.31234/osf.io/923rj_v2 Negative / Null Result ReportMedicine
Sajjad M, Ghorbaninejad P, Bitarafan V et al. · 2026 · The Journal of nutrition
Background The amino acids, L-leucine (Leu) and L-isoleucine (Ile), and the bitter substance, quinine, reduce postprandial glucose, stimulate insulin, and/or slow gastric emptying. Whether combining these stimuli can enhance these effects…
View details →DOI: 10.1016/j.tjnut.2025.101259 Negative / Null Result Report
Fathollahzadeh I, Hashemi A, Mehan M et al. · 2025 · Preprint
Abstract The existence of empathy in rodents and, more broadly, in lower mammals has been hotly debated. Each group has designed its apparatus to address this issue. While well-established methods for measuring cooperation are in the…
View details →DOI: 10.21203/rs.3.rs-6742141/v1 Negative / Null Result ReportMedicine
Lima Neta PP, Leal PPMS, Passos VHAA et al. · 2025 · Anais da Academia Brasileira de Ciencias
Leishmaniasis is a group of diseases caused by protozoa of the genus Leishmania . Current treatments exhibit high toxicity, high costs, and parasite resistance. Consequently, the search for new drugs is of utmost importance, and drug…
View details →DOI: 10.1590/0001-3765202520250377 Negative / Null Result ReportMedicine
Chou AK, Chiu CC, Chen YW et al. · 2025 · Fundamental & clinical pharmacology
The aim of this study was to examine the effects of intrathecal lidocaine combined with guanfacine or dexmedetomidine on nociceptive and motor blockade, in comparison to clonidine. Using a rat model of intrathecal injection, we evaluated…
View details →DOI: 10.1111/fcp.70057 Negative / Null Result Report
Furukawa H, Nishikawa Y, Saito A et al. · 2025 · Preprint
Abstract This study aimed to examine the effects of visual and auditory cues on step frequency (SF) and physiological load, measured by heart rate (HR), in runners. The experiment involved two runners—a main runner and a neighboring…
View details →DOI: 10.21203/rs.3.rs-6650523/v1 Negative / Null Result Report
Chen W, Zhang C, Guo W et al. · 2025 · Preprint
Apple is an important economic species, and it always suffered by biotic stress during its growth and development. Fungi and pests are two types of biotic stress that have significant destructive effects on apples. Besides, the LRR-RLKs…
View details →DOI: 10.22541/au.175022852.28343178/v1 Negative / Null Result Report
Zhang X, Li F, Li J et al. · 2025 · Preprint
Introduction Supervised physical activity (PA) interventions have demonstrated efficacy and safety in improving health outcomes among frail populations. However, the growing disparity between limited healthcare resources and the rapidly…
View details →DOI: 10.1101/2025.06.26.25330386 Negative / Null Result ReportMedicine
Mohapatra S, Rath S, Kapoor AG et al. · 2026 · American journal of ophthalmology
Purpose To evaluate whether 0.04% mitomycin C (MMC) application at the ostium enhances the outcome of non-endoscopic endonasal dacryocystorhinostomy (NEED) in individuals with primary acquired nasolacrimal duct obstruction (PANDO). Design…
View details →DOI: 10.1016/j.ajo.2025.10.005 Negative / Null Result ReportMedicine
Al-Jada DN, Takruri HR, Talib WH et al. · 2025 · Biochemical and Biophysical Research Communications
In this study, we investigated the effectiveness of combining the ketogenic diet (KD) with high-dose vitamin C (VitC) as adjuvant nutritional therapy to mitigate doxorubicin (DOX) toxicity, with a focus on cardiotoxicity, while enhancing…
Negative / Null Result ReportMedicine
Harvin S, Guetterman TC, Hirko KA et al. · 2026 · Contemporary clinical trials
This study developed and evaluated strategies to optimize recruitment and retention to a mobile health-supported dietary intervention trial, the MyBestGI Study. This included instituting a Personal Technology Assistant and enhancing the…
View details →DOI: 10.1016/j.cct.2026.108322 Negative / Null Result Report
Lagravinese G, Castellana G, Genco M et al. · 2025 · Preprint
Abstract Background: Chronic obstructive pulmonary disease (COPD) is associated with persistent dyspnea, reduced functional capacity, and significant cognitive and affective impairments. Pulmonary rehabilitation improves the physical and…
View details →DOI: 10.21203/rs.3.rs-6974767/v1 Negative / Null Result ReportMedicine
Firoozeh N, Park SY, Basavalingu D et al. · 2026 · Abdominal radiology (New York)
Objective To assess the diagnostic value of the delayed excretory phase in computed tomography urography (CTU) for detecting renal and urinary tract abnormalities and its impact on readers' confidence in patients with hematuria, given…
View details →DOI: 10.1007/s00261-025-05145-x Negative / Null Result ReportMedicine
Payette F, Kulp JC, Graves A et al. · 2025 · American journal of veterinary research
Objective To measure and compare CSF cytokine concentrations among horses with equine neuroaxonal dystrophy (eNAD)/equine degenerative myeloencephalopathy (EDM), horses with cervical vertebral stenotic myelopathy (CVSM), and control horses…
View details →DOI: 10.2460/ajvr.25.06.0212 Negative / Null Result ReportMedicine
Randy H, Perrin TP, Ghaith A et al. · 2025 · American journal of physiology. Regulatory, integrative and comparative physiology
Aging is associated with cerebrovascular impairment, increasing the risk for neurovascular and degenerative diseases. Intermittent hypoxic conditioning (IHC) has been proposed as a valuable strategy to enhance vascular health. However, its…
View details →DOI: 10.1152/ajpregu.00160.2025 Negative / Null Result ReportMedicine
Bonsu KO, Young SW, Lee T et al. · 2025 · Seminars in thrombosis and hemostasis
Acute pulmonary embolism (PE) is potentially life-threatening, with up to 15% risk of death. We compared four risk stratification models to identify outpatients at risk of mortality up to 90 days post acute PE. A retrospective cohort study…
View details →DOI: 10.1055/a-2621-0465 Negative / Null Result Report
Kim T, Lee H, Ryu S et al. · 2025 · Preprint
Abstract In mammalian cell-based bioprocesses, glycosylation of recombinant therapeutic proteins requires stringent control and monitoring as it may affect therapeutic efficacy and safety. The sialylation of glycosylated moieties plays an…
View details →DOI: 10.21203/rs.3.rs-7324359/v1 Negative / Null Result Report
Pulliainen H, Kataja E, Löyttyniemi E et al. · 2025 · Preprint
Abstract Background We examined whether an interactive four-dimensional (4D) ultrasound intervention decreases prenatal and early postnatal depressive symptoms and improves maternal-fetal attachment. Methods This randomized controlled…
View details →DOI: 10.21203/rs.3.rs-6672112/v1 Negative / Null Result ReportMedicine
Clouse DE, Collins EG, Khodakovskaya MV et al. · 2025 · Biomacromolecules
There is growing recognition that both cellulose nanocrystal (CNC) source and production scheme affect their physicochemical properties and dispersion behavior. However, how these differences affect CNC surface chemistry modification has…
View details →DOI: 10.1021/acs.biomac.4c01710 Negative / Null Result Report
Dikici B, Malinowski R, Kordaß J et al. · 2025 · Preprint
During non-rapid eye movement (NREM) sleep, cortical slow oscillation (SO; <1 Hz) and thalamic sleep spindle activity (12-15 Hz) interact through precise phase coupling to support memory consolidation. Slow oscillatory transcranial direct…
View details →DOI: 10.1101/2025.07.03.662520 Negative / Null Result Report
Junior PCGD, Vicente ACS, Santos IJd et al. · 2025 · Preprint
Abstract The study evaluated the effects of orange essential oil (OEO) as a feed additive on nutrient intake, digestibility, nitrogen balance, and rumen fermentation in meat sheep. Using ten rumen-cannulated Dorper × Santa Inês wethers in…
View details →DOI: 10.21203/rs.3.rs-6986736/v1 Negative / Null Result ReportMedicine
Badran PM, Stecca CM, de Souza de Castro JT et al. · 2025 · Clinical radiology
Aim Ovarian cancer is the most lethal gynecologic malignancy, with prognosis linked to stage at diagnosis. Ultrasonography is the first-line tool for adnexal mass evaluation, while computed tomography (CT) supports staging and surgical…
View details →DOI: 10.1016/j.crad.2025.107088 Negative / Null Result ReportMedicine
di Fonzo AR, Bertuzzi ML, Amusquibar MV et al. · 2025 · Animal reproduction science
Zinc oxide nanoparticles (ZnO-NPs) have been reported to enhance sperm cryopreservation in several species, but their effect on frozen llama semen remains unexplored. This study aims to evaluate the effect of ZnO-NPs on sperm parameters in…
View details →DOI: 10.1016/j.anireprosci.2025.107994 Negative / Null Result ReportOpen accessMedicine
Coste A, Wong AYS, Haguinet F et al. · 2025 · Pharmacoepidemiology and drug safety
Background Despite testing of epidemiological methods in US Claims databases for signal detection, such data sources have not become a routine capability. The Self Controlled Case Series (SCCS) is one of the most promising methods for drug…
View details →DOI: 10.1002/pds.70250 Negative / Null Result Report
Landínez-Martínez D, Grisales-Aguirre A · 2025 · Preprint
Background: /Objectives: Post-stroke cognitive impairment significantly impacts long-term functional outcomes, particularly in instrumental activities of daily living (IADLs). Working memory training (WMT) has emerged as a potential…
View details →DOI: 10.20944/preprints202506.1340.v1 Negative / Null Result ReportMedicine
Pereyra EV, Kravetz S, Lucero J et al. · 2025 · Limnologica
Freshwater ecosystems face significant threats worldwide, particularly from land use changes that impact biodiversity and ecosystem functions in rivers and streams. Essential elements such as carbon, nitrogen, and phosphorus play crucial…
Negative / Null Result ReportMedicine
Wakui N, Kawakubo S, Harayama M et al. · 2025 · Journal of the American Pharmacists Association : JAPhA
Background In Japan, human papillomavirus (HPV) vaccination rates remain low, partially owing to safety concerns from media reports. Pharmacies, as accessible health care facilities, often serve as sources of health information. However,…
View details →DOI: 10.1016/j.japh.2025.102901 Negative / Null Result Report
Zhang X, Wan C, Wang X et al. · 2025 · Preprint
Abstract Background: Despite considerable advances in therapeutic approaches for bronchopulmonary dysplasia (BPD), its incidence remains persistently high, with a troubling rise in moderate-to-severe cases. Given the progressive nature and…
View details →DOI: 10.21203/rs.3.rs-6936466/v1 Negative / Null Result ReportOpen accessMedicine
Freislederer F, Dimitriu M, Endell D et al. · 2026 · Journal of experimental orthopaedics
Purpose To determine whether augmentation with the subacromial bursa influences postoperative tendon healing, particularly regarding morphology and vascularity, after arthroscopic rotator cuff repair. Methods In this prospective…
View details →DOI: 10.1002/jeo2.70714 