e-ISSN: Pending
Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21257 results · page 194 of 709

Negative / Null Result ReportMedicine

More graminoids in community breaks the trade-off between forage production and quality to improve forage quality storage in alpine grasslands

Wu S, Liu Q, Li L et al. · 2025 · Agriculture, Ecosystems and Environment.

Forage production and quality, two crucial ecosystem functions of grasslands, often demonstrate a trade-off and are significantly affected by both grassland community characteristics and environmental factors. However, whether and how…

Negative / Null Result ReportMedicine

Behavioral Adaptation to Neck Radio-Collars and Its Relations with Temperament in Two Neotropical Psittacid Species.

de Almeida GN, de Jesus LG, Branco MEC et al. · 2026 · Journal of applied animal welfare science : JAAWS

Track devices can cause behavioral, physical, and physiological adverse effects, with individuals varying in how quickly they adapt to them. We examined behavioral effects of replica radio-collars on two captive psittacid species,…

View details →DOI: 10.1080/10888705.2026.2681557
Negative / Null Result ReportMedicine

Impact of tighter glycaemic targets on pregnancy outcomes in a multi-ethnic cohort with gestational diabetes: A retrospective, single centre observational study.

Huda MS, Margari N, Islam N et al. · 2026 · Obstetric medicine

Aims To determine the impact of tighter glycaemic targets for gestational diabetes. Methods Retrospective data analysis before and after introducing tighter glucose targets. Results In 2265 pregnancies there was no change in…

View details →DOI: 10.1177/1753495x261445509
Negative / Null Result ReportMedicine

An evaluation of anatomical and functional outcomes in patients undergoing retinectomy for proliferative vitreoretinopathy.

Uzlu D, Erdöl H, Bulanık ÖB et al. · 2026 · BMC ophthalmology

Background The objective of this study was to evaluate the anatomical and functional outcomes of patients who underwent relaxing retinotomy or retinectomy for retinal detachment complicated by proliferative vitreoretinopathy. Methods The…

View details →DOI: 10.1186/s12886-026-04904-8
Negative / Null Result ReportMedicine

Mental rotation performance after acute stress.

Richardson AE, VanderKaay Tomasulo MM · 2026 · BMC psychology

Background The need to mentally rotate objects is common in everyday activities (e.g., driving, loading suitcases in a car, playing 3D video games) and in specific professions (e.g., air traffic controllers, mechanics, pilots, surgeons).…

View details →DOI: 10.1186/s40359-026-04818-6
Negative / Null Result ReportMedicine

The Importance of Objective Functional and Balance Testing in Pediatric Anterior Cruciate Ligament Reconstruction for a Safe Return-To-Sport: A Two-Year Prospective Study.

Crippa M, Turati M, Flumian C et al. · 2026 · Journal of ISAKOS : joint disorders & orthopaedic sports medicine

Introduction/objectives Pediatric anterior cruciate ligament reconstruction (ACLR) outcomes, particularly long-term functional recovery and return-to-sport (RTS), remain debated and have not been well characterized in skeletally immature…

View details →DOI: 10.1016/j.jisako.2026.101149
Negative / Null Result ReportMedicine

Antifungal susceptibility of genital yeast isolates, Auckland, 2016-2025.

Morris AJ, McKinney WP, Roberts SA · 2026 · The New Zealand medical journal

Aim Our aim was to record current susceptibility results of genital yeast isolates and to compare the results to the previous report covering the period 2001-2015. Methods Genital yeast isolates had their antifungal susceptibility…

View details →DOI: 10.26635/6965.7444
Negative / Null Result ReportMedicine

Sono-anatomy of the supraclavicular region for ultrasound-guided subclavian vein catheterization: revaluation of a former method.

Berk AZ, Balaban O, Eman A et al. · 2026 · BMC anesthesiology

BACKGROUND/OBJECTIVE: Ultrasound-guided subclavian vein (SCV) catheterization offers an alternative approach to the classical jugular vein catheterization for central venous catheter placement. The objective of this study was to evaluate…

View details →DOI: 10.1186/s12871-026-03857-1
Negative / Null Result ReportOpen accessMedicine

Changes in macular structure after removal of epiretinal membrane in combined hamartomas of the retina and retinal pigment epithelium.

Lee CH, Kim KH, Choi YJ et al. · 2026 · Scientific reports

This study investigates the effect of epiretinal membrane (ERM) removal in the combined hamartomas of the retina and retinal pigment epithelium (CHRRPE) patients. In this retrospective, comparative case series, 15 CHRRPE patients were…

View details →DOI: 10.1038/s41598-026-39124-z
Negative / Null Result ReportMedicine

The impact of hormonal contraceptives containing estradiol, estradiol valerate, and estetrol on liver proteins, lipids, glucose, blood pressure, and bone. A literature review.

Cagnacci A, Xholli A, Gabbi L et al. · 2026 · The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception

Objective We investigated the metabolic profile induced by contraceptives containing body-identical oestrogens. Methods A literature search was made for articles on contraceptives with oestradiol/nomegestrol acetate (E2/NOMAc), oestradiol…

View details →DOI: 10.1080/13625187.2025.2596612
Negative / Null Result ReportMedicine

Quantification of Changes in Bifidobacteria and Lactobacilli Colony-forming Units During Rifaximin Treatment and Synbiotic Gel in Healthy Volunteers.

Cassís-Nosthas ML, Vorácková FV, Dzib FT et al. · 2026 · Journal of visualized experiments : JoVE

Although the gut microbiota is generally stable, it can be influenced by antibiotic treatment. Rifaximin, which is used to treat gastrointestinal disorders, is frequently administered with probiotics to reduce the risk of dysbiosis.…

View details →DOI: 10.3791/70201
Negative / Null Result ReportMedicine

Cerebral physiology following general anaesthesia with sevoflurane or propofol in healthy volunteers - a randomised, single-blind cross-over trial.

Madsen SS, Asghar MS, Lindberg U et al. · 2026 · Journal of applied physiology (Bethesda, Md. : 1985)

Although general anaesthesia is a very common medical procedure, knowledge of how the brain physiologically recovers remains limited. In this randomized cross-over trial, we investigated brain physiology during recovery from general…

View details →DOI: 10.1152/japplphysiol.01169.2025
Negative / Null Result ReportMedicine

Diurnal Rhythm in Blood Pressure Is Preserved in Hypertensive Mice Despite Therapy With Mineralocorticoid Receptor Antagonists.

Usai DS, Kudryavtseva O, Thomsen MB · 2026 · Journal of cardiovascular pharmacology

Abstract Human arterial blood pressure follows a circadian rhythm, where pressure is highest during the day and lowest during the night. Patients with hypertension can have either a preserved rhythm or a dampened rhythm with a lower…

View details →DOI: 10.1097/fjc.0000000000001812
Negative / Null Result ReportMedicine

Eight weeks of high-intensity interval training is insufficient to prevent sitting-induced endothelial dysfunction and microvascular impairment.

Kasai N, Ihara H, Iemitsu M et al. · 2026 · Experimental physiology

Prolonged sitting disrupts lower-limb endothelial and microvascular function, likely via reduced shear stress and blunted microvascular reactivity. We examined whether Tabata-style high-intensity interval training (HIIT) mitigates this…

View details →DOI: 10.1113/ep093646
Negative / Null Result ReportMedicine

Impact of lymphocyte p-glycoprotein activity on development of graft-versus-host disease after stem cell transplantation.

Nakamura S, Tajima S, Hirota T et al. · 2026 · International journal of hematology

Tacrolimus (TAC) is a pivotal immunosuppressant used to prevent graft-versus-host disease (GVHD) following hematopoietic stem cell transplantation (HSCT). However, because lymphocytes express P-glycoprotein (P-gp), which actively effluxes…

View details →DOI: 10.1007/s12185-026-04196-0
Negative / Null Result ReportMedicine

Sexual health following hyperbaric oxygen treatment in pelvic cancer survivors with radiation injuries: a longitudinal observational study.

Hauken MA, Gjestad R, Sekse RJT et al. · 2026 · The journal of sexual medicine

Background Hyperbaric oxygen therapy (HBOT) is an established treatment for pelvic late radiation tissue injuries (LRTIs) in cancer survivors, yet its impact on sexual health outcomes has previously not been examined. Aim To investigate…

View details →DOI: 10.1093/jsxmed/qdag189
Negative / Null Result ReportMedicine

Frequency Specificity of Narrowband Chirp and 2-1-2 Stimuli: Spectral Analyses.

Adjekum R, Small SA, Chan S et al. · 2026 · American journal of audiology

Purpose Narrowband (NB) chirps have recently been of great interest in audiology for the electrophysiological assessment of hearing in infants, but clinicians have little information about these new stimuli and how they compare to more…

View details →DOI: 10.1044/2025_aja-25-00145
Negative / Null Result ReportMedicine

Oxygen-enhanced MRI and multiple breath washout with Short extension reveal cystic fibrosis lung disease progression despite triple modulator therapy.

Short C, Semple T, Abkir M et al. · 2026 · Thorax

Introduction The current cystic fibrosis (CF) care era, while hugely welcome, raises new challenges, particularly the need for more sensitive pulmonary outcome measures. Seeking further optimisation, we previously developed a Short…

View details →DOI: 10.1136/thorax-2025-224648
Negative / Null Result ReportMedicine

Long-term risk of major adverse cardiovascular events after carotid endarterectomy-a 9-year prospective cohort study of the Athero-Express biobank.

Mol BM, de Bresser CJM, de Kleijn PV et al. · 2026 · European stroke journal

Carotid endarterectomy (CEA) is performed to lower the long-term risk of stroke in patients with carotid stenosis. Data evaluating long-term outcomes after CEA are scarce, but crucial for accurately determining long-term benefits. We aimed…

View details →DOI: 10.1093/esj/aakag060