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WASTE Journal
Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

AllReplication FailureNegative / Null Result ReportFailed Experiment ReportAbandoned HypothesisMethods Dead-EndShort NoteNull DatasetProtocol

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

By fieldMedicine 12,250Computer Science 750Biochemistry, Genetics and Molecular Biology 423Social Sciences 304Psychology 303Physics 280Neuroscience 250Economics, Econometrics and Finance 198Environmental Science 176Mathematics 159Agricultural and Biological Sciences 141Engineering 137

21257 results · page 193 of 709

Negative / Null Result ReportMedicine

Effectiveness and safety of superselective ophthalmic artery thrombolysis beyond 24h in central retinal artery occlusion.

Zhang, Li, Liao et al. · 2026 · International journal of ophthalmology

To evaluate the effectiveness and safety of superselective ophthalmic artery thrombolysis (SOAT) for central retinal artery occlusion (CRAO) beyond 24h after onset. This was a retrospective cohort study of CRAO patients treated from…

View details →DOI: 10.18240/ijo.2026.04.11
Negative / Null Result ReportMedicine

Microbial-chemical synergy in the immobilization of cadmium in contaminated floodplain soils: A field-mesocosm assessment of Sporosarcina pasteurii and SiO₂ nanoparticles.

Han, Wang, Shang et al. · 2026 · Journal of hazardous materials

Cadmium (Cd) accumulation in river floodplains is threatening grain safety and agro-ecosystem sustainability. We conducted a 10-month field-mesocosm experiment to evaluate the effectiveness, side effects and underlying mechanisms of three…

View details →DOI: 10.1016/j.jhazmat.2026.141870
Negative / Null Result ReportMedicine

A web-based prognostic nomogram incorporating VETC-associated imaging markers for predicting postoperative recurrence in hepatocellular carcinoma.

Zhao, Xie, Yu et al. · 2026 · BMC cancer

BACKGROUND: Vessels that encapsulate tumor clusters (VETC) is a powerful predictor of aggressive hepatocellular carcinoma (HCC) and associated with poor outcomes of HCC. Imaging surrogates of VETC potentially help predict postsurgical…

View details →DOI: 10.1186/s12885-026-15895-6
Negative / Null Result ReportMedicine

Dual Inhibition of GSK3 and JAK by BIO Suppresses Osteoblast Differentiation and Mineralization of Human Mesenchymal Cells.

Almuraikhi, Alkhamees, Tareen et al. · 2026 · Current issues in molecular biology

Glycogen synthase kinase-3 (GSK3) inhibition is a commonly used approach to promote osteogenic differentiation through activation of Wnt signaling. However, 6-bromoindirubin-3'-oxime (BIO), which is commonly used for GSK3 inhibition, also…

View details →DOI: 10.3390/cimb48030316
Negative / Null Result ReportMedicine

Serum anti-PLA2R negativity does not exclude glomerular PLA2R expression in primary membranous nephropathy.

Yıldırım Ş, İnci A, Karaduru Avcı A et al. · 2026 · Biomolecules & biomedicine

Primary membranous nephropathy (pMN) is a principal cause of nephrotic syndrome in adults. The identification of the M-type phospholipase A2 receptor (PLA2R) antigen has significantly advanced non-invasive management; however, the precise…

View details →DOI: 10.17305/bb.2026.14167
Negative / Null Result ReportMedicine

Multimodal perioperative monitoring of intracranial pressure surrogates and cerebral oxygenation during laparoscopic surgery: implications for early cognitive outcomes.

Aba O, Yalçın Sezen G, Ersoy Karka O · 2026 · BMC anesthesiology

Purpose This study aimed to evaluate perioperative changes in optic nerve sheath diameter (ONSD) and regional cerebral oxygen saturation (rSO₂) using noninvasive monitoring techniques during laparoscopic abdominal surgery, and to assess…

View details →DOI: 10.1186/s12871-026-03978-7
Negative / Null Result ReportMedicine

The relationship between health literacy and preoperative anxiety among surgical patients: A cross-sectional survey study.

Çetinkaya F, Uslu E · 2026 · Journal of perioperative practice

Objective This study aimed to determine whether there is a relationship between patients' health literacy levels and their preoperative anxiety during the preoperative period. Design An analytical cross-sectional study. Methods The…

View details →DOI: 10.1177/17504589261441562
Negative / Null Result ReportOpen accessMedicine

Correlation between anterior teeth retraction and pharyngeal airway dimension changes in bimaxillary protrusion cases.

Sugiarta AP, Anggani HS, Purbiati M · 2025 · Journal of orthodontic science

Objective This study aims to demonstrate the correlation between anterior tooth retraction and changes in the dimensions of the pharyngeal airway in cases of bimaxillary protrusion. Materials and methods Changes in dental parameters and…

View details →DOI: 10.4103/jos.jos_23_25
Negative / Null Result ReportMedicine

Central corneal thickness, corneal endothelial cell density, and morphology in myopic eyes of young Chinese candidates for refractive surgery.

Wu, Zhang, Wang et al. · 2026 · Frontiers in ophthalmology

To assess central corneal thickness (CCT), as well as the density and morphology of corneal endothelial cells (ECD) in myopic eyes. A total of 400 patients scheduled for myopic refractive surgery were consecutively enrolled in this study.…

View details →DOI: 10.3389/fopht.2026.1769734
Negative / Null Result ReportMedicine

Association of Air Pollution Exposure with Incident Cataract Surgery and Neovascular Age-Related Macular Degeneration in 2 French Nationwide Cohorts.

Gayraud, Lequy, Hucteau et al. · 2026 · Ophthalmology science

Age-related macular degeneration (AMD) and cataracts are part of the leading causes of blindness globally, with oxidative stress being a key factor in their development. Air pollution, known to exacerbate oxidative stress, may contribute…

View details →DOI: 10.1016/j.xops.2026.101099
Negative / Null Result ReportMedicine

In-pack combination of ultrasonication and sous-vide accelerates goat meat tenderization: gene expression and biochemical changes during early post-mortem storage.

Sai-Ut, Indriani, Srisakultiew et al. · 2026 · Food science of animal resources

Meat tenderness is key to consumer acceptance but is challenged by goat meat's leanness and high connective tissue content. A promising solution is the in-pack combination of ultrasonication (US) and sous-vide (SV) technologies to enhance…

View details →DOI: 10.1007/s44463-025-00028-7
Negative / Null Result ReportMedicine

Valorization of Sour Cherry Seeds in Beef Meatballs: Effect on Quality, Lipid Oxidation, Texture Profile, Acrylamide Formation and Antioxidant Activity.

Savaş, Kavrut, Engin · 2026 · Foods (Basel, Switzerland)

In the study, the effects of adding sour cheery seed powder at different concentrations (0%, 0.5%, 1%, and 1.5%) on the pH, water content, lipid oxidation, cooking loss, color, TPC, antioxidant activity (DPPH and ABTS), texture, and…

View details →DOI: 10.3390/foods15050968
Negative / Null Result ReportMedicine

Analyzing the impact of power loss reduction in radial distribution network using diverse distributed generators by utilizing ZIP load models.

Manikanta, Kumar, Mani et al. · 2026 · Scientific reports

Distributed generators (DGs) are recent emerging technologies which are executed in distribution system (DS) to reduce power losses (PLs). However, optimal location and sizing of DG (OLSDG) remain a challenging combinatorial optimization…

View details →DOI: 10.1038/s41598-026-55639-x
Negative / Null Result ReportMedicine

Beyond the "Cold" Barrier: Redefining the Clinical Paradigm of Immune Checkpoint Inhibitor Therapy in Ovarian Cancer.

Wu, Zhang, Xi et al. · 2026 · Critical reviews in oncology/hematology

Ovarian cancer remains an immunologically "cold" tumor, with early all-comer immune checkpoint inhibitor (ICI) trials largely negative despite underlying immunogenicity. This review takes a clinician-centric, stage-specific view linking…

View details →DOI: 10.1016/j.critrevonc.2026.105459
Negative / Null Result ReportMedicine

Persistent deficits in the motor unit following mono and dual administration of SMN up-regulators in the SmnΔ7 mouse model of spinal muscular atrophy.

Partlova, Comley, Haigh et al. · 2026 · Experimental neurology

Spinal muscular atrophy (SMA) is characterized by motor neuron loss and neuromuscular junction (NMJ) pathology. Although SMN-upregulating therapies such as Nusinersen markedly improve survival and motor function for many patients,…

View details →DOI: 10.1016/j.expneurol.2026.115898