A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
19820 results in Negative / Null Result Report · page 178 of 661
Littleton, Thomas, Woodhead et al. · 2026 · Frontiers in immunology
Ischemic stroke thrombi contain complex immunothrombotic components, including neutrophil extracellular traps (NETs), which contribute to thrombus stability and resistance to fibrinolysis. However, the endogenous triggers of NETosis within…
Gadag, Arora, Kaskie et al. · 2026 · Health services research
We examined how the expansion of Medicaid audio-only coverage (MAOC) was associated with changes in mental health visit rates at Federally Qualified Health Centers (FQHCs). We used publicly available FQHC-level Uniform Data Systems (UDS)…
Parirokh, Manochehrifar, Nakahee et al. · 2026 · Iranian endodontic journal
The close relationship between pulp stones in the pulp chamber and pulp neurovascular tissues suggests that the presence of pulp stones may compromise successful anesthesia. The present study assessed the effect of pulp stone presence on…
Xiao, Zheng, Guo et al. · 2026 · Patient preference and adherence
Hypoglycemia is a frequent and burdensome complication in adolescents with type 1 diabetes mellitus (T1DM). Despite its high prevalence, structured interventions targeting hypoglycemia coping confidence remain scarce, especially in China.…
Coşansu, Osoria, Juneja · 2026 · Journal of food protection
This study investigated the effects of sodium chloride (NaCl), grape seed extract (GSE), and cooling duration on the growth of Clostridium perfringens in cooked ground beef during slow exponential cooling. Meat samples containing…
MacInnes, Ferrer-Vicens, Hancock et al. · 2026 · Blood advances
The RNA-binding protein IMP1 is a developmentally expressed, post-transcriptional regulator involved in mRNA stability and translation. In the erythroid lineage, IMP1 was found expressed in fetal, but repressed in adult erythroid cells,…
Guendouz, Devriendt · 2026 · Molecular immunology
In livestock species such as pigs, antibiotics are frequently used during weaning, a period of increased susceptibility to infections. However, the emergence and spread of antimicrobial resistance necessitate alternative strategies to…
Lahaye, Haegdorens, Franck et al. · 2026 · European geriatric medicine
To evaluate the effectiveness of a structured, team-delivered intervention based on cognitive behavioural therapy for insomnia (CBT-I) on sleep and related outcomes in nursing home residents. A cluster randomised controlled trial with…
da Costa, Ramirez, de Carvalho et al. · 2026 · Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment
Acrylamide and 4-methylimidazole (4-MEI) are heat-induced contaminants formed during coffee roasting, raising concerns due to their potential toxicological effects. Considering the limited information about the occurrence of these…
Hu, El-Sappah, Chen et al. · 2026 · Frontiers in plant science
Understanding the temperature sensitivity ( Q 10 ) of soil respiration (RS) and its response to nitrogen (N) and phosphorus (P) fertilization is essential for predicting soil carbon dynamics under climate change. However, seasonal…
Ziltzer, Bulbul, Barry et al. · 2026 · The Laryngoscope
To investigate whether routine involvement of the medical hospitalist service (MHS) in postoperative medical management of head and neck cancer (HNC) patients undergoing major ablative head and neck surgery with free tissue transfer (FTT)…
Jiménez, Lopez-Lluch, Barón-López et al. · 2026 · Psychoneuroendocrinology
The cortisol awakening response (CAR) is thought to represent an anticipatory mechanism to prepare for upcoming demands. In sport, competition increases in the CAR have been reported, although findings remain inconsistent. A study on…
Hou, Yu, Shen et al. · 2026 · Archives of oral biology
This study explored low-magnitude high-frequency (LMHF) mechanical vibration as a strategy to expand mandibular condylar chondrocyte (MCC) populations with enhanced chondrogenic phenotypes, providing high-quality cellular resources for…
Abelovska, Malinova, Sucha et al. · 2026 · Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
This pilot study evaluated "Your Health Belongs to You," a six-week group intervention combining psychotherapy and exercise to improve quality of life, emotional health, and symptom management in individuals with Multiple Sclerosis (MS),…
Shih, Hsu, Yang et al. · 2026 · Anticancer research
Oral cancer represents a major health burden in Taiwan, with tobacco use, alcohol consumption, and betel quid chewing recognized as predominant environmental risk factors. Matrix metalloproteinase-9 (MMP-9) has been implicated in tumor…
van Keulen, Voogt, Kleinjan et al. · 2026 · JMIR mHealth and uHealth
Excessive alcohol consumption among adolescents and young adults is a serious health problem. Dynamically tailored interventions could reduce their excessive drinking. We therefore developed "What Do You Drink" (WDYD), a 17-week…
Wang, Matsuyama, Kiuchi et al. · 2026 · Journal of dentistry
To examine whether multiple routine oral health practices reduce all-cause mortality, and how these associations are modified by sociodemographic, behavioral, and health related factors. Data were derived from the Japan Gerontological…
Cengiz, Yıldırım, Yaşaroğlu et al. · 2026 · Dysphagia
This study aimed to investigate the effects of Tongue Hold Maneuver (THM), Mendelsohn Maneuver (MM), and Effortful Swallow Maneuver (ESM) performed under different gravitational positions (90° sitting, 45° sitting, supine, and…
Bakhshalipoor, Bolandi, Nahidi et al. · 2026 · Scientific reports
This study evaluated the effects of double nanoemulsions of saffron petal extract (DN-SPE), stabilized with soybean (SPI) and pea protein isolates (PPI), alone or combined with Lepidium sativum L. seed gum (LSG) (SL or PL), on the quality…
Kawamura, Masaki, Kato · 2026 · Journal of pharmacological sciences
Acetylcholine-mediated modulation of pain-associated behaviors has been progressively well described. The mechanisms of cholinergic antinociception have been reported to involve the activation of nAChRs or mAChRs modulating GABAergic…
Rezagholizadeh, Tavassoli, Saeedi et al. · 2026 · Brain research bulletin
Traumatic Brain Injury (TBI) is an important contributing factor to cognitive impairment, frequently linked to disturbances in synaptic plasticity and metaplasticity. Astrocytes, as essential regulators of synaptic function, are crucial…
Wang, Li, Zhang et al. · 2026 · Child development
This study examines how center-based parenting interventions aimed at improving early child development in rural China affect the mental health of caregivers. Data from an analytic sample of 615 caregiver-child dyads (children aged 6 to 24…
Gurcay, Bilgin, Sert et al. · 2026 · Advances in skin & wound care
Frailty, resulting from physical and psychological factors, may lead to the development of care dependency in people diagnosed with diabetic foot. This study was conducted to determine frailty and care dependency in patients diagnosed with…
Molnes, Vinje, Opheim et al. · 2026 · Translational animal science
In June 2023, an incident at a Norwegian feed mill caused pig feed being over-supplemented with sodium selenite (NaSe), resulting in feed selenium concentrations ranging from 2.47 to 4.70 mg Se/kg feed from sodium selenite (NaSe),…
Cui, Luo, Tajika et al. · 2026 · Journal of affective disorders
This study aimed to examine the effectiveness of smartphone-delivered cognitive behavioral therapy (CBT) in participants with subthreshold depression, considering the potential influence of physical comorbidities. In this secondary…
Bai, Kim, Cao et al. · 2026 · Social psychiatry and psychiatric epidemiology
Universal Credit (UC) is a major UK welfare reform that consolidates six means-tested benefits into a single monthly payment, aiming to simplify benefits delivery and incentivize labor market participation. However, concerns have emerged…
Sun, Gong, Liu et al. · 2026 · Molecules (Basel, Switzerland)
A novel urea complexation technology was developed based on the agglomeration phenomenon induced by ambient-temperature agitation of a ternary system consisting of urea, water and fatty acid ethyl esters (EEs). The agglomeration phenomenon…
Guleria, Horijan, Kumar et al. · 2026 · Scientific reports
The study aimed to evaluate fumigation and repellent properties of essential oils (EOs) from Juniperus macropoda leaves and cedarwood, Cedrus deodara against storage pests viz., Tribolium castaneum and Callosobruchus maculatus. Further,…
Heidari, Amiri, Mobarakeh · 2026 · Journal of speech, language, and hearing research : JSLHR
Age-related hearing loss (ARHL) has been associated with cognitive decline. Although bilingualism may influence cognitive performance, its interaction with hearing loss remains unclear. This study aimed to investigate the effects of ARHL…
Wang, Lv, Zeng et al. · 2026 · Neurocritical care
This study compared the effectiveness of noninvasive positive pressure ventilation (NIPPV) and high-flow nasal cannula (HFNC) in preventing reintubation among neurosurgical intensive care patients following extubation. A retrospective…