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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21253 results · page 178 of 709

Negative / Null Result Report

#4204 MULTIPARAMETRIC MAGNETIC RESONANCE IMAGING BIOMARKERS OUTPERFORM LAB BIOMARKERS FOR PREDICTING PROGRESSION OF DIABETIC KIDNEY DISEASE

Paul Hockings, Kianoush Makvandi, Johannes Hulthe et al. · 2023 · Nephrology Dialysis Transplantation

Abstract Background and Aims We recently showed that comprehensive non-contrast multiparametric Magnetic Resonance Imaging (mpMRI) allowed functional and structural assessment of diabetic kidney disease (DKD) and that an imaging endpoint,…

View details →DOI: 10.1093/ndt/gfad063c_4204Cited by 1
Negative / Null Result Report

Environmental Policy Performance and Political Development: Do Democracies Outperform Authoritarian Regimes?

David S. Kelleher, Geum-Soo Kim · 2014 · International Studies Review

The pursuit of sustainable development initially centered on understanding how economic development and environmental quality are related. More recently, many have focused on how political development and environmental quality are related.…

View details →DOI: 10.1163/2667078x-01501002Cited by 1
Negative / Null Result Report

The influence of pre-university education resources on school dropout and the unemployment rate in Romania is significant?

Marian Zaharia · 2024 · Journal of Research and Innovation for Sustainable Society

In Romania, especially at county level, school dropout rate in primary and secondary education, school dropout rate in high school and professional education, as well as unemployment rate, differ significantly from one county to another,…

View details →DOI: 10.33727/jriss.2024.2.22:202-214Cited by 1
Negative / Null Result Report

No Significant Association Between Herpes Zoster and Breast Cancer: A German Outpatient Study with over 120,000 Participants

Vedanth D. Krishnan, Niklas Gremke, André Hajek et al. · 2024 · Clinics and Practice

Purpose: The purpose of this study was to investigate a possible association between Herpes Zoster (HZ) and the subsequent diagnosis of breast cancer (BC). Methods: Utilizing the Disease Analyzer database, anonymized medical records from…

View details →DOI: 10.3390/clinpract14060218Cited by 1
Negative / Null Result Report

Two Familial Cases of Hb Tyne Confirm Instability as Cause of Low Expression

Beverley M. Pullon, Stephen O. Brennan · 2017 · Thalassemia Reports

We report a second occurrence of hemoglobin (Hb) Tyne, [β5 (A2) Pro>Ser] HBB:c.16C>T(p.Pro6Ser), which like the first case was associated with normal hematology. We verified the variant was mildly unstable by showing it was greatly…

View details →DOI: 10.4081/thal.2017.6504Cited by 1
Negative / Null Result Report

Assessing the Performance of 8 AI Chatbots in Bibliographic Reference Retrieval: Grok and DeepSeek Outperform ChatGPT, but None are Entirely Accurate

Álvaro Cabezas-Clavijo, Pavel Sidorenko-Bautista · 2026 · Journal of Data and Information Science

Abstract Purpose This study evaluates the reliability of eight generative artificial intelligence chatbots—including ChatGPT, Claude, Gemini, and DeepSeek—when functioning as autonomous agents for academic bibliographic generation,…

View details →DOI: 10.1515/jdis-2025-0326Cited by 1
Negative / Null Result Report

Gene losses did not stop the evolution of big brains

Cristian Cañestro, Vittoria Roncalli · 2018 · eLife

Elephants and fruit bats have evolved large brains even though they have lost a gene that is fundamental to the supply of energy to the brain when glucose is not available.

View details →DOI: 10.7554/elife.41912Cited by 1
Negative / Null Result Report

Molecular Diagnostic Techniques Used to Confirm an Unusual Case of BAPoma

Aaron Atkinson, Konstantinos Linos, Shaofeng Yan et al. · 2017 · The FASEB Journal

Study Objective BAP1 (BRCA1‐associated protein 1) is a critical tumor suppressor that promotes genome stability and DNA damage response, in addition to other cellular processes. BAP1 maps to 3p21 and is a nuclear localized deubiquitinating…

View details →DOI: 10.1096/fasebj.31.1_supplement.807.17Cited by 1
Negative / Null Result Report

261 LENGTH OF HOSPITAL STAY AND THE ASSOCIATION WITH READMISSION AFTER UNCOMPLICATED ESOPHAGECTOMY. SIGNIFICANT HOSPITAL VARIATION IN THE NETHERLANDS.

D Voeten, L Werf, J Sandick et al. · 2020 · Diseases of the Esophagus

Abstract Prolonged length of hospital stay is a negative outcome of esophageal cancer surgery, not only for the patient; it also leads to increased hospital costs. Within the scope of value-based health care, this study aimed to analyze…

View details →DOI: 10.1093/dote/doaa087.53Cited by 1
Negative / Null Result Report

The Effect of Income on Daily Physical Activity Levels in Americans

Jacob Foster, null null, null null et al. · 2023 · John Heinrichs Scholarly & Creative Activities Day

I analyze the relationship between income range and exercise level. The data that I have selected for this project was obtained from the Health Information National Trends Survey website. The specific question that the respondents were…

View details →DOI: 10.58809/nxdl4613Cited by 1
Negative / Null Result Report

Perioperative Echocardiography to Confirm Correct Central Venous Catheter Placement: A Case Report

Parag Gharde, Sourangshu Sarkar, Kalpana Irpachi et al. · 2020 · A&A Practice

Central venous catheterization is widely regarded as a safe procedure by anesthesiologists and intensivists, but insertion complications and catheter malposition remain challenges for the clinicians performing central venous catheter (CVC)…

View details →DOI: 10.1213/xaa.0000000000001291Cited by 1
Negative / Null Result Report

Detection of clinically significant prostate cancer by micro-ultrasound-informed systematic biopsy during MRI/micro-ultrasound fusion biopsy

Betty Wang, Stacey Broomfield, Anaïs Medina Martín et al. · 2022 · Canadian Urological Association Journal

Introduction: High-resolution micro-ultrasound (microUS) is a novel imaging technique that may visualize clinically significant prostate cancer (csPCa), including those missed by magnetic resonance imaging (MRI), in real-time during…

View details →DOI: 10.5489/cuaj.8094Cited by 1
Negative / Null Result Report

Performance of sustainable investments: do green-labeled bonds outperform green-unlabeled bonds?

Linh Tu Ho, Christopher Gan, Wei Yang et al. · 2025 · Studies in Economics and Finance

Purpose The increase in demand for sustainable investments globally raises the question of benefits of investing in green bonds. A green label attracts investors because it represents less information asymmetry on green bonds with lower…

View details →DOI: 10.1108/sef-08-2024-0536Cited by 1
Negative / Null Result Report

Humans Outperform Machines at the Bilingual Shannon Game

Marjan Ghazvininejad, Kevin Knight · 2016 · Entropy

We provide an upper bound for the amount of information a human translator adds to an original text, i.e., how many bits of information we need to store a translation, given the original. We do this by creating a Bilingual Shannon Game…

View details →DOI: 10.3390/e19010015Cited by 1
Negative / Null Result Report

An impedance threshold device did not improve carotid blood flow in a porcine model of prolonged cardiac arrest

Benedict Kjaergaard, Hans O. Holdgaard, Sigridur O. Magnusdottir et al. · 2020 · Journal of Translational Medicine

Abstract Background An impedance threshold device (ITD) was developed to increase venous return to the heart and therefore increase cardiac output and organ blood flow during cardiopulmonary rescue (CPR). Basic CPR aims to maintain…

View details →DOI: 10.1186/s12967-020-02264-5Cited by 1
Negative / Null Result Report

A novel approach to off-clamp partial nephrectomy demonstrates significant improvements in renal injury in an experimental porcine model

Daniel Olvera-Posada, Shouzhe Lin, Ghaleb Aboalsamh et al. · 2017 · Canadian Urological Association Journal

Introduction: We sought to design a partial nephrectomy (PN) with contralateral total nephrectomy porcine model and assess the underlying mechanisms of ischemia reperfusion injury (IRI) after PN using a novel, clinically approved resection…

View details →DOI: 10.5489/cuaj.4305Cited by 1
Negative / Null Result Report

Type III collagen formation is significantly associated with risk of outcome in HFpEF patients but loses its significant association with underlying AF

E Angeli, A Reese-Petersen, A Gonzalez et al. · 2022 · European Heart Journal

Abstract Introduction Heart failure with preserved ejection fraction (HFpEF) is the most common type of heart failure, associated with high morbidity and mortality. Atrial fibrillation (AF) has been associated with structural remodelling…

View details →DOI: 10.1093/eurheartj/ehac544.792Cited by 1
Negative / Null Result Report

Granuloma Annulare, Autoimmune Thyroiditis, and Lichen Sclerosus in a Woman: Randomness or Significant Association?

Mariele De Paola, Anastasia Batsikosta, Luca Feci et al. · 2013 · Case Reports in Dermatological Medicine

We report a 60-year-old Caucasian female with a 2-year history of diffused granuloma annulare (GA), who presented for the simultaneous occurrence of genital lichen sclerosus (LS) and autoimmune thyroiditis (AT). In our opinion this…

View details →DOI: 10.1155/2013/289084Cited by 1
Negative / Null Result Report

Patient leaflets on respiratory tract infections did not improve shared decision making and antibiotic prescriptions in a low-prescriber setting

Andreas Plate, Stefania Di Gangi, Christian Garzoni et al. · 2024 · Scientific Reports

Abstract Patient information leaflets can reduce antibiotic prescription rates by improving knowledge and encouraging shared decision making (SDM) in patients with respiratory tract infections (RTI). The effect of these interventions in…

View details →DOI: 10.1038/s41598-024-55166-7Cited by 1
Negative / Null Result Report

The specific leaf area of forest species subjected to different degrees of shading did not differ when detached and full leaflets were compared

Jacqueline Lucia Guimarães, Cristina Moll Hüther, Ramonn Diego Barros de Almeida et al. · 2020 · Semina: Ciências Agrárias

Studies of forest species under different environmental conditions are essential for enhancing our understanding of plant-environment relationships. Different light conditions interfere with the production of seedlings within forests, and…

View details →DOI: 10.5433/1679-0359.2020v41n5supl1p1837Cited by 1
Negative / Null Result Report

Educators' perceptions of a system‐informed positive education program: A study of most significant change

Stephen Burrowes, Adam Gerace, Tessa Benveniste et al. · 2024 · Future in Educational Research

Abstract There are increasing calls for positive education to integrate holistic and system approaches to both the understanding and implementation of mental health and well‐being interventions across all levels of a school community. The…

View details →DOI: 10.1002/fer3.63Cited by 1
Negative / Null Result Report

Study: The Lack of Significant Association of the Catechol‐ O ‐Methyl Transferase (COMT) Gene Polymorphism in Violent Offenders with Mental Retardation

Aysun Baransel Isir, Alper Ibrahim Dai, Muradiye Nacak et al. · 2010 · Journal of Forensic Sciences

Abstract: Little is known about criminality of cognitively impaired people and also there have been no reports on the relationship between catechol‐ O ‐methyl transferase (COMT) and committed Mental Retardation (MR) subjects. In the…

View details →DOI: 10.1111/j.1556-4029.2009.01205.xCited by 1
Negative / Null Result Report

Soil biological and physical measurements did not improve the predictability of corn response to phosphorus fertilization

Ben Groebner, Jason D. Clark, Jeffrey D. Svedin et al. · 2024 · Agronomy Journal

Abstract Including soil health and physical measurements with traditional soil fertility measurements has the potential to improve corn ( Zea mays L.) P fertilizer recommendations. The objectives for this study were to (1) evaluate the…

View details →DOI: 10.1002/agj2.21612Cited by 1
Negative / Null Result Report

Impact of Significant Hemoglobin Drop Without Bleeding in Patients Undergoing Transcatheter Aortic Valve Replacement

Pavan Reddy, Ilan Merdler, Cheng Zhang et al. · 2024 · Journal of the American Heart Association

Background Hemoglobin (Hgb) drop without bleeding is common among patients undergoing transcatheter aortic valve replacement; however, the clinical implications of significant Hgb drop have not been fully evaluated. Methods and Results…

View details →DOI: 10.1161/jaha.123.032291Cited by 1