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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21697 results · page 177 of 724

Negative / Null Result Report

Did the COVID-19 Lockdown Reduce Smoking Rate in Adolescents?

Seunghyup Lee, Mingee Choi, Dahyun Kim et al. · 2022 · International Journal of Environmental Research and Public Health

This study examined the temporal trend of smoking use and the prevalent differences in the use of different types of cigarettes for Korean adolescents before and during the COVID-19 pandemic. In Korea, all use of e-cigarettes, including…

View details →DOI: 10.3390/ijerph20010139Cited by 6
Negative / Null Result Report

Can we find the missing men in clinics? Clinic attendance by sex and HIV status in rural South Africa

Safiyya Randera-Rees, Wende Clarence Safari, Dickman Gareta et al. · 2023 · Wellcome Open Research

Background: HIV-negative men are over-represented in tuberculosis (TB) prevalence surveys including the first South African national TB prevalence survey in 2018. Traditionally, TB screening is focused in clinics. We aimed to determine the…

View details →DOI: 10.12688/wellcomeopenres.16702.2Cited by 6
Negative / Null Result Report

Ancient DNA indicates a century of overhunting did not reduce genetic diversity in Pacific Walruses (Odobenus rosmarus divergens)

Kendall K. Mills, Kyndall P. B. Hildebrandt, Kathryn M. Everson et al. · 2024 · Scientific Reports

Abstract Pacific Walruses ( Odobenus rosmarus divergens [Illiger 1815]) are gregarious marine mammals considered to be sentinels of the Arctic because of their dependence on sea ice for feeding, molting, and parturition. Like many other…

View details →DOI: 10.1038/s41598-024-57414-2Cited by 6
Negative / Null Result Report

Pregnancy Has No Clinically Significant Effect on the Pharmacokinetics of Bupropion or Its Metabolites

Emily E. Fay, Lindsay C. Czuba, Jennifer E. Sager et al. · 2021 · Therapeutic Drug Monitoring

Background: Bupropion (BUP) is a chiral antidepressant and smoking cessation aide with benefits and side effects correlated with parent and active metabolite concentrations. BUP is metabolized by CYP2B6, CYP2C19, and CYP3A4 to hydroxy-BUP…

View details →DOI: 10.1097/ftd.0000000000000885Cited by 6
Negative / Null Result Report

Diversity, equity and inclusion work: a difference that makes a difference … ?

Ann Armstrong · 2024 · Equality, Diversity and Inclusion: An International Journal

Purpose I examine if current diversity, equity and inclusion (DEI) initiatives can actually accomplish what they aim and claim to do. I argue that perforce they cannot, as they remain instruments of capitalist corporations and other…

View details →DOI: 10.1108/edi-10-2023-0325Cited by 6
Negative / Null Result Report

The significant role of educational status in PKU patients: the beneficial effect of psychological support in depression

Kostas Iakovou, Kleopatra Schulpis · 2019 · International Journal of Adolescent Medicine and Health

Abstract Introduction Classical Phenylketonuria (PKU) is a metabolic disease characterized by high phenylalanine (phe) levels in blood and brain. PKU patients are commonly treated with low phe diet supplemented with amino acid free…

View details →DOI: 10.1515/ijamh-2018-0233Cited by 6
Negative / Null Result Report

ReplicOpter: A replicate optimizer for flexible docking

Omar N. A. Demerdash, Amanda Buyan, Julie C Mitchell · 2010 · Proteins: Structure, Function, and Bioinformatics

Abstract We present a computationally efficient method for flexible refinement of docking predictions that reflects observed motions within a protein's structural class. Using structural homologs, we derive deformation models that capture…

View details →DOI: 10.1002/prot.22811Cited by 6
Negative / Null Result Report

Who did what to whom, and what did we already know?

Tania Ionin, Maria Goldshtein, Tatiana Luchkina et al. · 2021 · Linguistic Approaches to Bilingualism

Abstract This paper reports on an experimental investigation of what second language (L2) learners and heritage speakers of Russian know about the relationship between word order and information structure in Russian. The participants…

View details →DOI: 10.1075/lab.20045.ionCited by 6
Negative / Null Result Report

Can masked synonym priming replicate masked translation priming?

Naoko Witzel · 2019 · Quarterly Journal of Experimental Psychology

This study examines whether synonyms are represented similarly to translation equivalents in the bilingual mind. In particular, this study investigated whether there is masked synonym priming such that it will simulate masked translation…

View details →DOI: 10.1177/1747021819848683Cited by 6
Negative / Null Result Report

Failing to replicate predicts citation declines in psychology

Cory J. Clark, Paul Connor, Calvin Isch · 2023 · Proceedings of the National Academy of Sciences

With a sample of 228 psychology papers that failed to replicate, we tested whether the trajectory of citation patterns changes following the publication of a failure to replicate. Across models, we found consistent evidence that failing to…

View details →DOI: 10.1073/pnas.2304862120Cited by 6
Negative / Null Result Report

The Differential Impact of the 2000 Canadian Graphic Warning Label Policy on Smoking Prevalence by Sex and Education: A Difference-in-Difference-in-Difference Model

Bukola Usidame, Gang Meng, James F Thrasher et al. · 2022 · Nicotine & Tobacco Research

Abstract Introduction Using a quasiexperimental design, we compared the impact of the 2000 Canadian introduction of graphic warning labels (GWLs) on differences in smoking prevalence by sex and education, to the United States, where no…

View details →DOI: 10.1093/ntr/ntac122Cited by 6
Failed Experiment Report

Classical stabilities of multiplicative inverse difference and adjoint functional equations

B. V. Senthil Kumar, Khalifa Al-Shaqsi, Hemen Dutta · 2020 · Advances in Difference Equations

Abstract The aim of this present article is to investigate various classical stability results of the multiplicative inverse difference and adjoint functional equations $$ m_{d} \biggl(\frac{rs}{r+s} \biggr)-m_{d} \biggl( \frac{2rs}{r+s}…

View details →DOI: 10.1186/s13662-020-02680-3Cited by 6
Negative / Null Result Report

Changes in caregiver depression, anxiety, and satisfaction with family relationships in families of children who did and did not undergo resective epilepsy surgery

Natalie L. Phillips, Elysa Widjaja, Mary Lou Smith · 2020 · Epilepsia

Abstract Objective To evaluate longitudinal changes in caregiver depression, anxiety, and family relationships following resective surgery for pediatric drug‐resistant epilepsy (DRE). Methods This multicenter cohort study involved 177…

View details →DOI: 10.1111/epi.16672Cited by 5
Negative / Null Result Report

Why Mathematical Probability Failed to Emerge from Ancient Gambling

Stephen Kidd · 2020 · Apeiron

Abstract The emergence of mathematical probability has something to do with dice games: all the early discussions (Cardano, Galileo, Pascal) suggest as much. Although this has long been recognized, the problem is that gambling at dice has…

View details →DOI: 10.1515/apeiron-2018-0045Cited by 5
Negative / Null Result Report

Significant hot hand effect in the game of cricket

Sumit Kumar Ram, Shyam Nandan, Didier Sornette · 2022 · Scientific Reports

Abstract We investigate the predictability and persistence of individual and team performance (hot-hand effect) by analyzing the complete recorded history of international cricket. We introduce an original temporal representation of…

View details →DOI: 10.1038/s41598-022-14980-7Cited by 5
Failed Experiment Report

Replicate ice-coring system testing

Jay A. Johnson, Nicolai B. Mortensen, Christopher J. Gibson et al. · 2014 · Annals of Glaciology

Abstract Drilling the WDC06A borehole at the West Antarctic Ice Sheet (WAIS) Divide with the Deep Ice Sheet Coring (DISC) drill began in December 2007 and was successfully completed in December 2011 to a depth of 3405 m. The design and…

View details →DOI: 10.3189/2014aog68a034Cited by 5
Negative / Null Result Report

Evidence of a significant rotational non-LTE effect in the CO 2 4.3 µm PFS-MEX limb spectra

Alexander A. Kutepov, Ladislav Rezac, Artem G. Feofilov · 2017 · Atmospheric Measurement Techniques

Abstract. Since January 2004, the planetary Fourier spectrometer (PFS) on board the Mars Express satellite has been recording near-infrared limb spectra of high quality up to the tangent altitudes ≈ 150 km, with potential information on…

View details →DOI: 10.5194/amt-10-265-2017Cited by 5
Negative / Null Result Report

Allograft nephrectomy vs. no nephrectomy for failed renal transplants

Michelle McDonald · 2023 · Frontiers in Nephrology

The role of allograft nephrectomy (AN) in failed renal transplants is a topic of debate, owing to controversial results reported in the literature and the fact that most of the studies are limited by a retrospective design and small…

View details →DOI: 10.3389/fneph.2023.1169181Cited by 5
Negative / Null Result Report

Calcifying Phytoplankton Demonstrate an Enhanced Role in Greenhouse Atmospheric CO2 Regulation

Karin Kvale, Wolfgang Koeve, Nadine Mengis · 2021 · Frontiers in Marine Science

The impact of calcifying phytoplankton on atmospheric CO 2 concentration is determined by a number of factors, including their degree of ecological success as well as the buffering capacity of the ocean/marine sediment system. The relative…

View details →DOI: 10.3389/fmars.2020.583989Cited by 5
Negative / Null Result Report

Significant effect of compositional grading on SAGD performance in a fractured carbonate heavy oil reservoir

Hossein Ghalenavi, Saeid Norouzi-Apourvari, Mahin Schaffie et al. · 2019 · Journal of Petroleum Exploration and Production Technology

Abstract In reservoir simulation, the fluid composition is usually assumed uniform for the whole reservoir, while in many reservoirs, oil and gas composition changes with depth. This phenomenon which is known as compositional grading could…

View details →DOI: 10.1007/s13202-019-00744-zCited by 5
Negative / Null Result Report

Failed supernova remnants

Daichi Tsuna · 2021 · Publications of the Astronomical Society of Japan

Abstract In a failed supernova, partial ejection of the progenitor’s outer envelope can occur due to weakening of the core’s gravity by neutrino emission in the protoneutron star phase. We consider emission when this ejecta sweeps up the…

View details →DOI: 10.1093/pasj/psab041Cited by 5
Negative / Null Result Report

A single residue substitution accounts for the significant difference in thermostability between two isoforms of human cytosolic creatine kinase

Huihui Liu, Yan-Song Gao, Xiang-Jun Chen et al. · 2016 · Scientific Reports

Abstract Creatine kinase (CK) helps maintain homeostasis of intracellular ATP level by catalyzing the reversible phosphotransfer between ATP and phosphocreatine. In humans, there are two cytosolic CK isoforms, the muscle-type (M) and the…

View details →DOI: 10.1038/srep21191Cited by 5
Negative / Null Result Report

Preventative effects of antioxidants on changes in sebocytes, outer root sheath cells, and Cutibacterium acnes -pretreated mice by particulate matter: No significant difference among antioxidants

Mi Hee Kwack, Dae-Lyong Ha, Weon Ju Lee · 2022 · International Journal of Immunopathology and Pharmacology

Objectives Particulate matter (PM) is an air pollutant that can damage human skin; antioxidants have shown some efficacy in alleviating PM-induced skin inflammation. We investigated the antioxidant effects of punicalagin,…

View details →DOI: 10.1177/03946320221112433Cited by 5