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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21697 results · page 176 of 724

Negative / Null Result Report

Does SLOPE outperform bridge regression?

Shuaiwen Wang, Haolei Weng, Arian Maleki · 2021 · Information and Inference: A Journal of the IMA

Abstract A recently proposed SLOPE estimator [6] has been shown to adaptively achieve the minimax $\ell _2$ estimation rate under high-dimensional sparse linear regression models [25]. Such minimax optimality holds in the regime where the…

View details →DOI: 10.1093/imaiai/iaab025Cited by 6
Negative / Null Result Report

Significant individual change should be used as a lower bound for anchor based estimates of meaningful change on patient-reported outcome scores

John Devin Peipert, David Cella, Ron D. Hays · 2024 · Quality of Life Research

Abstract Interpretation of patient-reported outcome (PRO) scores has been supported by identifying score thresholds or ranges that indicate clinical importance. There has been a recent focus on the estimation of meaningful within patient…

View details →DOI: 10.1007/s11136-024-03788-9Cited by 6
Negative / Null Result Report

Association between Intraoperative Blood Pressure Drop and Clinically Significant Hypoperfusion in Abdominal Surgery: A Cohort Study

Zbigniew Putowski, Szymon Czajka, Łukasz J. Krzych · 2021 · Journal of Clinical Medicine

The recent consensus by the Perioperative Quality Initiative (POQI) on intraoperative hypotension (IOH) stated that mean arterial pressure (MAP) below 60–70 mmHg is associated with myocardial infarction (MI), acute kidney injury (AKI),…

View details →DOI: 10.3390/jcm10215010Cited by 6
Negative / Null Result Report

50 Years of Cumulative Open-Source Data Confirm Stable and Robust Biodiversity Distribution Patterns for Macrofungi

Haili Yu, Tiejun Wang, Andrew Skidmore et al. · 2022 · Journal of Fungi

Fungi are a hyper-diverse kingdom that contributes significantly to the regulation of the global carbon and nutrient cycle. However, our understanding of the distribution of fungal diversity is often hindered by a lack of data, especially…

View details →DOI: 10.3390/jof8090981Cited by 6
Negative / Null Result Report

Do Bilinguals Outperform Monolinguals in Switching Tasks? Contrary Evidence for Nonlinguistic and Linguistic Switching Tasks

Ernest Mas-Herrero, Daniel Adrover-Roig, María Ruz et al. · 2021 · Neurobiology of Language

Abstract The benefits of bilingualism in executive functions are highly debated. Even so, in switching tasks, these effects seem robust, although smaller than initially thought (Gunnerud et al., 2020; Ware et al., 2020). By handling two…

View details →DOI: 10.1162/nol_a_00059Cited by 6
Negative / Null Result Report

Micro-ultrasound for the detection of clinically significant prostate cancer in biopsy-naive men with negative MRI

Patrick Albers, Jacob Bennett, Moira Evans et al. · 2024 · Canadian Urological Association Journal

Introduction: Despite a negative magnetic resonance imaging (MRI), some patients may still harbor clinically significant prostate cancer (csPCa, Gleason grade group ≥2). High-resolution micro-ultrasound (microUS) is a novel imaging…

View details →DOI: 10.5489/cuaj.8626Cited by 6
Negative / Null Result Report

Education Finance Reform and the Great Recession: Did State Policy and Fiscal Federalism Improve Education Spending, School Resources, and Student Achievement in Pennsylvania?

Matthew P. Steinberg, Rand Quinn, J. Cameron Anglum · 2020 · Journal of Education Finance

abstract: We estimate the impact of school finance reform on adequate and equitable district spending, school resources and student achievement in Pennsylvania. From the 2008-09 to the 2010-11 school years, amid the Great Recession,…

View details →DOI: 10.1353/jef.2020.a760723Cited by 6
Negative / Null Result Report

Did expanded access to denture services improve chewing ability in the Korean older population? Results of a regression discontinuity analysis

Nam-Hee Kim, Ichiro Kawachi · 2020 · Scientific Reports

Abstract The Korean National Health Insurance expanded the dental insurance in 2012 to cover denture services for older adults. We analyzed whether the new policy improved of chewing ability in the eligible population. We used regression…

View details →DOI: 10.1038/s41598-020-68189-7Cited by 6
Negative / Null Result Report

Another Brick to Confirm the Efficacy of Rigosertib as Anticancer Agent

Alessio Malacrida, Marie Deschamps-Wright, Roberta Rigolio et al. · 2023 · International Journal of Molecular Sciences

Rigosertib is a small molecule in preclinical development that, due to its characteristics as a dual PLK1 and PI3K inhibitor, is particularly effective in counteracting the advance of different types of tumors. In this work, we evaluated…

View details →DOI: 10.3390/ijms24021721Cited by 6
Negative / Null Result Report

Significant association of nicotine reinforcement and cue reactivity: a translational study in humans and rats

Kevin Butler, Benoît Forget, Stephen J. Heishman et al. · 2021 · Behavioural Pharmacology

Relapse is common amongst smokers attempting to quit and tobacco cue-induced craving is an important relapse mechanism. Preclinical studies commonly use cue-induced reinstatement of nicotine seeking to investigate relapse neurobiology.…

View details →DOI: 10.1097/fbp.0000000000000607Cited by 6
Negative / Null Result Report

No significant difference between Australian heat wave impacts of Modoki and eastern Pacific El Niño

Tammas F. Loughran, Sarah E. Perkins‐Kirkpatrick, Lisa V. Alexander et al. · 2017 · Geophysical Research Letters

Abstract The influence of two El Niño types on the frequency of summer heat wave days in Australia is investigated using both observations and an atmospheric climate model. The two basic spatial variants of El Niño are the traditional…

View details →DOI: 10.1002/2017gl073231Cited by 6
Negative / Null Result Report

A Meta-Epidemiological Study of Positive Results in Clinical Nutrition Research: The Good, the Bad and the Ugly of Statistically Significant Findings

Konstantinos Gkiouras, Maria-Eleftheria Choleva, Aikaterini Verrou et al. · 2022 · Nutrients

Positive (statistically significant) findings are easily produced in nutrition research when specific aspects of the research design and analysis are not accounted for. To address this issue, recently, a pledge was made to reform nutrition…

View details →DOI: 10.3390/nu14235164Cited by 6
Negative / Null Result Report

Extracting statistically significant eddy signals from large Lagrangian datasets using wavelet ridge analysis, with application to the Gulf of Mexico

Jonathan M. Lilly, Paula Pérez-Brunius · 2021 · Nonlinear Processes in Geophysics

Abstract. A method for objectively extracting the displacement signals associated with coherent eddies from Lagrangian trajectories is presented, refined, and applied to a large dataset of 3770 surface drifters from the Gulf of Mexico. The…

View details →DOI: 10.5194/npg-28-181-2021Cited by 6
Negative / Null Result Report

Root-knot nematodes demonstrate temporal variation in host penetration

Shova Mishra, Peter DiGennaro · 2020 · Journal of Nematology

Abstract Root-knot nematodes (RKN; Meloidogyne spp.) are obligate plant parasites that require constant communication with their host to establish and maintain specialized feeding cells. The intimacy of this interaction likely requires…

View details →DOI: 10.21307/jofnem-2020-037Cited by 6
Negative / Null Result Report

The Continuous Fragility Index of Statistically Significant Findings in Studies Based on High Levels of Evidence Comparing Interventions for Femoroacetabular Impingement Syndrome

Juan Bernardo Villarreal-Espinosa, Zeeshan A. Khan, Kyleen Jan et al. · 2025 · The American Journal of Sports Medicine

Background: Critical analysis of studies with high level of evidence has relied on the significance set by the reported P values. However, this strategy steers readers toward categorical interpretation of the data; therefore, a more…

View details →DOI: 10.1177/03635465241283967Cited by 6
Negative / Null Result Report

No statistically significant difference in long term scarring outcomes of pediatric burns patients treated surgically vs. those treated conservatively

Riyam Mistry, Fadi Issa · 2022 · Frontiers in Surgery

Introduction Paediatric burns are a common clinical presentation. The long-term scar outcomes in paediatric burns patients are relatively unknown as most are discharged after 6 weeks follow up, apart from the small number that are followed…

View details →DOI: 10.3389/fsurg.2022.727983Cited by 6
Negative / Null Result Report

Photobiomodulation therapy in dogs undergoing TPLO after cranial cruciate ligament rupture shows promise but no statistically significant difference in a randomized trial

Oscar A. Chavez, Walter Renberg, Natalia Cernicchiaro · 2024 · American Journal of Veterinary Research

Abstract OBJECTIVE Effect of photobiomodulation therapy (PBMT) in patients with CCLR after TPLO surgery by measuring C-reactive protein (CRP), percentage weight bearing, lameness using a short form of a composite measure pain scale,…

View details →DOI: 10.2460/ajvr.23.06.0138Cited by 6
Negative / Null Result Report

Post-Harvest Regulated Deficit Irrigation in Chardonnay Did Not Reduce Yield but at Long-Term, It Could Affect Berry Composition

Maria Prats-Llinàs, Joaquim Bellvert, Mercè Mata et al. · 2019 · Agronomy

Future increases in temperatures are expected to advance grapevine phenology and shift ripening to warmer months, leaving a longer post-harvest period with warmer temperatures. Accumulation of carbohydrates occurs during post-harvest, and…

View details →DOI: 10.3390/agronomy9060328Cited by 6
Negative / Null Result Report

Find the “best evidence” of the relationship between network embeddedness and enterprise disruptive innovation performance

Neng Shen, Jing Zhang, Yangchun Cao · 2024 · Business Process Management Journal

Purpose In the context of open innovation, more and more enterprises are leveraging innovation networks to drive disruptive innovation performance, but there is no consensus on the relationship between network embeddedness and enterprise…

View details →DOI: 10.1108/bpmj-03-2024-0191Cited by 6
Negative / Null Result Report

Instructional Video did not reduce anxiety during pediatric cast removal: a prospective cohort study

Brandon J. Barnes, Cherry Abdou, Kyle Wendling et al. · 2020 · Journal of Pediatric Orthopaedics B

The aim of the study was to determine if the use of an Instructional Video will decrease anxiety during cast removal. We enrolled 60 healthy children undergoing their first cast removal following conservative fracture treatment. Patients…

View details →DOI: 10.1097/bpb.0000000000000773Cited by 6
Negative / Null Result Report

Did an urban perinatal health programme in Rotterdam, the Netherlands, reduce adverse perinatal outcomes? Register-based retrospective cohort study

Hendrik CC de Jonge, Jacqueline Lagendijk, Unnati Saha et al. · 2019 · BMJ Open

Objectives To study the effect of an urban perinatal health programme in Rotterdam, the Netherlands, on perinatal outcomes. Design A retrospective cohort study with difference-in-differences analysis using individual-level perinatal…

View details →DOI: 10.1136/bmjopen-2019-031357Cited by 6
Negative / Null Result Report

Combination pretest probability assessment and D-dimer did not reduce outpatient imaging for venous thromboembolism in a tertiary care hospital emergency department

Sarah Ingber, Rita Selby, Jacques Lee et al. · 2014 · CJEM

ABSTRACT Introduction: Venous thromboembolism (VTE) is difficult to diagnose yet potentially life threatening. A low-risk pretest probability (PTP) assessment combined with a negative Ddimer can rule out VTE in two-thirds of outpatients,…

View details →DOI: 10.2310/8000.2013.130986Cited by 6
Negative / Null Result Report

A school-based supplementary food programme in rural Kenya did not reduce children's intake at home

Constance A Gewa, Suzanne P Murphy, Robert E Weiss et al. · 2012 · Public Health Nutrition

Abstract Objective To examine changes in energy intake along with markers of dietary quality (animal-source energy and protein intakes) among household members in the presence of supplementary school feeding in rural Kenya. Design A…

View details →DOI: 10.1017/s1368980012003266Cited by 6
Negative / Null Result Report

How Did They Grow: An Intervention to Reduce Stunted Growth in Low‐Income Mexican‐American Children

Elizabeth Reifsnider, Cha‐Nam Shin, Michael Todd et al. · 2016 · Research in Nursing & Health

Abstract Growth stunting is a complex phenomenon related to undernutrition that can contribute to developmental delay, cognitive deficits, and small size and obesity in adulthood. Stunted growth, defined as height for age below the 5th…

View details →DOI: 10.1002/nur.21714Cited by 6
Negative / Null Result Report

Did the ACA reduce job-lock and spur entrepreneurship?

Simon Condliffe, Matt B. Saboe, Sabrina Terrizzi · 2017 · Journal of Entrepreneurship and Public Policy

Purpose The purpose of this paper is to assess the effect of the recent Affordable Care Act’s (ACA) Dependent Mandate (DM) that requires health insurers to extend dependent coverage to the children of their insured, up to age 26. The DM…

View details →DOI: 10.1108/jepp-09-2016-0032Cited by 6