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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21253 results · page 172 of 709

Negative / Null Result Report

Employing Cluster Analysis to Detect Significant Cloud 3D RT Effect Indicators

Michael J. Foster, Dana E. Veron · 2010 · Journal of the Atmospheric Sciences

Abstract Three-dimensional cloud field morphology contributes to scene-averaged cloud reflectivity, but climate models do not currently incorporate methods of identifying situations where this contribution is substantial. This work…

View details →DOI: 10.1175/2010jas3414.1Cited by 2
Negative / Null Result Report

How Did Early Modern Scholars Study Early Maps?

Matthew H Edney · 2024 · Cartographic Perspectives

The two standard Anglophone historiographies of the history of cartography (Skelton 1972, Harley 1987) situated the field’s origins in the early modern era, or even in the later Middle Ages. Yet “history” and “cartography” are both…

View details →DOI: 10.14714/cp105.1881Cited by 2
Negative / Null Result Report

A real life retrospective analysis of drug expenditure reveals no significant cost difference between infliximab and adalimumab in the treatment of adult crohn's disease: Figure 1

C A Lamb, M Price, M Robinson et al. · 2011 · Gut

Introduction The revised NICE guidance on the use of infliximab and adalimumab for the treatment of Crohn's disease, released in May 2010, has suggested biologics be prescribed as a planned therapy until treatment failure or until…

View details →DOI: 10.1136/gut.2011.239301.534Cited by 2
Failed Experiment Report

Significant Enhancement of Electrocaloric Effect in Ferroelectric Polymer via Nanopores Interfacial Engineering

Youhao Xiong, Zilong Xie, Sen Xue et al. · 2025 · Advanced Functional Materials

Abstract Ferroelectric polymer‐based electrocaloric (EC) materials are promising for next‐generation solid‐state refrigeration due to their high entropy change, eco‐friendliness, lightweight, and flexibility. The practical application of…

View details →DOI: 10.1002/adfm.202507417Cited by 2
Negative / Null Result Report

Failed Intrauterine Pregnancy: What Is a Failed Pregnancy, What Is Not?

TIMOTHY P. CANAVAN · 2017 · Clinical Obstetrics & Gynecology

Pregnancy failure is defined as a lack of sonographic evidence of current or expected viability. Technologic advances in ultrasound imaging continue to redefine diagnostic criteria of pregnancy failure or success. When evaluating a…

View details →DOI: 10.1097/grf.0000000000000301Cited by 2
Negative / Null Result Report

Britain’s Failed Attempt at Monetary and Fiscal Exceptionalism

David Marsh · 2023 · The Economists’ Voice

Abstract The autumn 2022 economic upheavals that brought down British Prime Minister Liz Truss’s government represented an ultimate extension of a high-risk exercise in British exceptionalism: the June 2016 referendum decision to leave the…

View details →DOI: 10.1515/ev-2023-0021Cited by 2
Negative / Null Result Report

Modulated stimuli demonstrate asymmetric interactions between hearing and vision

Quoc C. Vuong, Mark Laing, Anjana Prabhu et al. · 2019 · Scientific Reports

Abstract The nature of interactions between the senses is a topic of intense interest in neuroscience, but an unresolved question is how sensory information from hearing and vision are combined when the two senses interact. A problem for…

View details →DOI: 10.1038/s41598-019-44079-5Cited by 2
Negative / Null Result Report

A case report about adalimumab-induced radiologically isolated syndrome: A significant side effect of tumour necrosis factor inhibitors

Joshua Onasanya, Renée A Beach · 2021 · SAGE Open Medical Case Reports

Tumor necrosis factor-α antagonists have become a therapeutic mainstay for various inflammatory diseases including Hidradenitis Suppurativa. Despite their clinical efficacy, these medications have been associated with the rare development…

View details →DOI: 10.1177/2050313x211003057Cited by 2
Negative / Null Result Report

The small impact of p-hacking marginally significant results on the meta-analytic estimation of effect size

Juan Botella, Manuel Suero, Juan I. Durán et al. · 2021 · Anales de Psicología

La etiqueta p-hacking (pH) se refiere a un conjunto de prácticas oportunistas destinadas a hacer que sean significativos algunos valores p que deberían ser no significativos. Algunos han argumentado que debemos prevenir y luchar contra el…

View details →DOI: 10.6018/analesps.433051Cited by 2
Negative / Null Result Report

Variations in Polysomnographic Indices of Obstructive Sleep Apnea following Lingual Tonsil Hypertrophy Excision: Is the Difference Significant?

Ashraf Wahba, Khaled Abdelaal, Ayman Yehia et al. · 2022 · Medicina

Background and Objectives: Obstructive sleep apnea (OSA) is a sleep-related respiratory disorder that affects between 5% and 20% of the population. In obstructive sleep apnea, lingual tonsillar hypertrophy (LTH) has been suggested as a…

View details →DOI: 10.3390/medicina58050573Cited by 2
Negative / Null Result Report

Casp8p41: The Protean Mediator of Death in CD4 T-cells that Replicate HIV

Rahul Sampath, Nathan W. Cummins, Andrew D. Badley · 2016 · Journal of Cell Death

HIV cure is now the focus of intense research after Timothy Ray Brown (the Berlin patient) set the precedent of being the first and only person cured. A major barrier to achieving this goal on a meaningful scale is an elimination of the…

View details →DOI: 10.4137/jcd.s39872Cited by 2
Negative / Null Result Report

Failure to Replicate: A Sign of Scientific Misconduct?

Helene Hill, Joel Pitt · 2014 · Publications

Repeated failures to replicate reported experimental results could indicate scientific misconduct or simply result from unintended error. Experiments performed by one individual involving tritiated thymidine, published in two papers in…

View details →DOI: 10.3390/publications2030071Cited by 2
Negative / Null Result Report

Less risk of patellofemoral degeneration without significant clinical and survivorship difference for distal tibial tuberosity high tibial osteotomy compared to biplanar high tibial osteotomy over a mid-term follow-up

Ke Li, Hengbing Guo, Fenglong Sun et al. · 2024 · Journal of Orthopaedic Surgery

Purpose This study aims to compare the mid-term radiographic, clinical results and survivorship between distal tibial tuberosity high tibial osteotomy (DTT-HTO) and conventional biplanar medial open-wedge high tibial osteotomy (cOW-HTO).…

View details →DOI: 10.1177/10225536241273925Cited by 2
Negative / Null Result Report

Dataset of replicate Apollo sample magnetizations bearing on impacts and absence of a long-lived lunar dynamo

Rory D. Cottrell, Tinghong Zhou, John A. Tarduno · 2024 · Scientific Data

Abstract The absence or presence of a lunar paleomagnetosphere is important because it bears directly on the volatile content of the regolith and exploration targets for Artemis and other missions to the Moon. Recent paleointensity study…

View details →DOI: 10.1038/s41597-024-03626-0Cited by 2
Negative / Null Result Report

Validation of an ampicillin selection protocol to enrich for mutants of Listeria monocytogenes unable to replicate on fresh produce

Victor Jayeola, C Parsons, L Gorski et al. · 2019 · FEMS Microbiology Letters

ABSTRACT Several outbreaks of listeriosis have implicated fresh produce but genetic factors required for growth of Listeria monocytogenes on produce remain poorly characterized. Based on the fact that β-lactam antibiotics only kill…

View details →DOI: 10.1093/femsle/fnz076Cited by 2
Negative / Null Result Report

Liposomes functionalized with fungi-targeting peptide demonstrate increased interaction with Candida albicans

Ronnie LaMastro, Noel Vera-Gonzalez, Kayla Campbell et al. · 2021 · Access Microbiology

Candida albicans infections can be challenging to treat, as current antifungal drugs exhibit poor water solubility and host toxicity. To overcome these issues, new methods of drug delivery are needed. Liposomes have been shown to be an…

View details →DOI: 10.1099/acmi.cc2021.po0180Cited by 2
Negative / Null Result Report

Significant Differences and Experimental Designs Do Not Necessarily Imply Clinical Relevance: Effect Sizes and Causality Claims in Antidepressant Treatments

Iván Sánchez-Iglesias, Celia Martín-Aguilar · 2023 · Journal of Clinical Medicine

Clinical trials are the backbone of medical scientific research. However, this experimental strategy has some drawbacks. We focused on two issues: (a) The internal validity ensured by clinical trial procedures does not necessarily allow…

View details →DOI: 10.3390/jcm12093181Cited by 2
Failed Experiment Report

Four Reasons Why Heterodox Academy Failed

Nathan Cofnas · 2022 · Academic Questions

Seven years ago, under the leadership of Jonathan Haidt, Heterodox Academy set out to organize a meaningful resistance to the reigning social justice orthodoxy on campus. “Seven years later,” writes Nathan Cofnas, “you can count HxA’s…

View details →DOI: 10.51845/35.4.4Cited by 2
Negative / Null Result Report

Analysis of Pediatric Pulpotomy, Pulpectomy, and Extractions in Primary Teeth Revealed No Significant Association with Subsequent Root Canal Therapy and Extractions in Permanent Teeth: A Retrospective Study

Arash Farhadian, Mayce Arreem Issa, Karl Kingsley et al. · 2024 · Pediatric Reports

Recent evidence suggests that an ever-growing number of pediatric patients require invasive treatments such as root canal therapy (RCT) in their permanent dentition, albeit with little information about risk factors such as prior invasive…

View details →DOI: 10.3390/pediatric16020038Cited by 2
Negative / Null Result Report

Can sector-specific REIT strategies outperform a diversified benchmark?

Alex Moss, Andrew Clare, Stephen Thomas et al. · 2017 · Journal of European Real Estate Research

Purpose The authors in this paper aim to investigate the performance of different portfolios of REITs which specialise by property type compared to the performance of a diversified free-float market capitalisation-weighted benchmark index…

View details →DOI: 10.1108/jerer-11-2016-0042Cited by 2
Negative / Null Result Report

When Do Single‐Species Occupancy Models Outperform Multispecies Models?

Gavin G. Cotterill, Douglas A. Keinath, Tabitha A. Graves · 2025 · Ecology and Evolution

ABSTRACT Occupancy models have become increasingly popular for species monitoring and assessment, in part, because detection/non‐detection data are readily obtained using a variety of methods. Multispecies occupancy models (MSOMs) can…

View details →DOI: 10.1002/ece3.72315Cited by 2
Negative / Null Result Report

Association of Diuretic Dosage With Outcomes in Patients With Hemodynamically Significant Isolated Tricuspid Valve Regurgitation

Vidhu Anand, Christopher G. Scott, Khaled Ali et al. · 2025 · Journal of the American Heart Association

Background Tricuspid valve surgery is recommended for severe isolated tricuspid regurgitation (TR) if symptoms persist despite optimal medical therapy. The definition of optimal therapy for TR is unclear beyond managing underlying…

View details →DOI: 10.1161/jaha.124.039989Cited by 2
Negative / Null Result Report

A single session of a beach volleyball exergame did not improve state anxiety level in healthy adult women

Vinnycius Nunes de Oliveira, Ricardo Borges Viana, João Victor Rosa de Freitas et al. · 2024 · BMC Sports Science, Medicine and Rehabilitation

Abstract This study evaluated the acute effect of the exergame Kinect Sports ® beach volleyball on state anxiety level in adult women. Thirty healthy adult women (age: 21 [4] years, body mass: 54.70 [19.50] kg, height: 1.61 ± 0.05 m, and…

View details →DOI: 10.1186/s13102-024-00859-9Cited by 2