A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
20217 results in Negative / Null Result Report · page 170 of 674
Yan Li, Jin-Kou Zhao, Ming Wang et al. · 2010 · Virology Journal
Abstract Background Immunoassays composed of screening and confirmation are the established algorithm to confirm HIV infection in China, with a Western blot result as the final diagnosis. Case presentation In this report, three late-stage…
Susan C. Connors, Shemiah Nyaude, Amelia Challender et al. · 2017 · Academic Medicine
Problem In medical education, evaluating outcomes from programs intended to transform attitudes or influence career trajectories using conventional methods of monitoring is often difficult. To address this problem, the authors adapted the…
Sara Ortiz-Toquero, Francisco J. Muñoz-Negrete, Gema Rebolleda · 2020 · Journal of Neuro-Ophthalmology
Background: Optic disc drusen (ODD) are a dynamic phenomenon, and their appearance, size, and relative location may change. The purpose of this study is to evaluate and quantify the longitudinal changes of buried ODD with enhanced depth…
Michael Zieger, Steffen Springer · 2021 · Pacific Conservation Biology
In nature conservation and environmental protection, there is the thesis that charismatic flagship species generate a high level of public interest that can be used for nature conservation efforts. Among other things, Google Trends has…
Eric C. Sun, Franklin Dexter, Alex Macario et al. · 2015 · Anesthesiology
AbstractAbstract In a review of payments from private insurers for five commonly billed anesthesia codes in 229 counties in the United States from 2002 through 2010, payments to anesthesiologists in more concentrated markets were not…
B Christensen, C Zhu, M Niazy et al. · 2023 · Translational Animal Science
Abstract At weaning, one hundred pigs (21 d of age; 6.96 ± 0.23 kg BW) were used to determine the effect of partially replacing soybean meal (SBM) in corn- and SBM-based nursery diets on growth performance, fecal scores, Escherichia coli…
Todd A. Astorino, Danielle Emma · 2021 · Sports
Maximal oxygen uptake (VO2max) is strongly associated with endurance performance as well as health risk. Despite the fact that VO2max has been measured in exercise physiology for over a century, robust procedures to ensure that VO2max is…
Alon Shechter, Mirae Lee, Danon Kaewkes et al. · 2023 · Journal of the American Heart Association
Background There are limited data on repeat mitral transcatheter edge‐to‐edge repair for recurrent significant mitral regurgitation (MR). Methods and Results We conducted a single‐center, retrospective analysis of consecutive patients…
Hyunjae Jeon, Sean Krysak, Steven J. Pfeiffer et al. · 2022 · International Journal of Athletic Therapy and Training
Second anterior cruciate ligament (ACL) injury has similar biomechanical risk factors as primary injury. Standard of care rehabilitation does not adequately mitigate these biomechanical risks. This study examined the effectiveness of a…
Qin Huo, Xuezhao Sun, Tingting Wu et al. · 2022 · Frontiers in Veterinary Science
Choline is an essential nutrient in ruminant diets, which contributes to the fundamental biological functions of the animal. However, choline is easily degraded in the rumen before it can be absorbed. Rumen-protected choline (RPC)…
Koji Yoshida, Lucian Krille, Steffen Dreger et al. · 2017 · Journal of Radiation Research
Abstract Computed tomography (CT) is an essential tool in modern medicine and is frequently used to diagnose a wide range of conditions, particularly in industrial countries, such as Japan and Germany. However, markedly higher doses of…
N. Hirter, A. Letko, I. M. Häfliger et al. · 2020 · Animal Genetics
Summary Entropion is a known congenital disorder in sheep presumed to be heritable but no causative genetic variant has been reported. Affected lambs show a variable inward rolling of the lower eyelids leading to blindness in severe cases.…
Kerri Mocko, Cynthia S. Jones · 2021 · American Journal of Botany
Premise In semiarid regions, decreasing rainfall presents a challenge to perennial seedlings that must reach sufficient size to survive the first year’s seasonal drought. Attaining a large storage organ size has been hypothesized to…
Olivia Wootton, Alexey A. Shadrin, Christine Mohn et al. · 2023 · Molecular Psychiatry
Abstract Reaction time variability (RTV), reflecting fluctuations in response time on cognitive tasks, has been proposed as an endophenotype for many neuropsychiatric disorders. There have been no large-scale genome-wide association…
Rafael Mellado, Claudio Cubillos · 2025 · Applied Sciences
Generative artificial intelligence tools, such as Microsoft Copilot, are transforming the teaching of programming by providing real-time feedback and personalized assistance; however, their impact on learning, motivation, and cognitive…
Sascha Hoffmann, Marina Ott, Franziska Bobbert et al. · 2024 · DIGITAL HEALTH
Objective Internet-based healthcare is a crucial facet of telemedicine. Here, we examine telemedicine methods in perioperative care for gynecological surgery from a patient's perspective. We aim to understand the patients’ needs during…
Theodore Anton, Timothy Clifton · 2024 · Journal of Cosmology and Astroparticle Physics
Abstract We consider the form of Hubble diagrams that would be constructed by observers in universes that are homogeneous but anisotropic, when averaged over suitably large length-scales. This is achieved by ray-tracing in different…
Mekala Sundaram, Nicole L Gottdenker, Patrick R Stephens · 2025 · BioScience
Abstract An enduring mystery in Ebolavirus research is what host species maintain the virus in the wild. Despite the efforts of multiple research groups over decades, no primary reservoir has ever been identified. To the contrary, finding…
Charlie Curtsinger, Emery D. Berger · 2013 · ACM SIGPLAN Notices
Researchers and software developers require effective performance evaluation. Researchers must evaluate optimizations or measure overhead. Software developers use automatic performance regression tests to discover when changes improve or…
Rossalina Christanti, Andreas Ari Sukoco · 2022 · Journal of Education and Learning (EduLearn)
What the job market demanded in the last few decades is overwhelming. Universities are working hard to meet the quality required by the job markets and it took a lot of effort, physically and mentally. Recently, the Minister of Education…
Gillianne Bowman, Thierry Huber, Vanessa Burg · 2023 · Energies
Today, an energy transition is underway to tackle the problems of climate change and energy sufficiency. For this transition to succeed, it is essential to use all available renewable energy resources most efficiently. However, renewable…
Guoqing Diao, Dan-yu Lin · 2020 · BMC Genetics
Abstract Background Associations between haplotypes and quantitative traits provide valuable information about the genetic basis of complex human diseases. Haplotypes also provide an effective way to deal with untyped SNPs. Two major…
Marcelo Boareto, Nestor Caticha · 2014 · Microarrays
Microarray data analysis typically consists in identifying a list of differentially expressed genes (DEG), i.e., the genes that are differentially expressed between two experimental conditions. Variance shrinkage methods have been…
Şeyma Çağlar‐Özhan, Perihan Tekeli, Selay Arkün‐Kocadere · 2025 · Journal of Computer Assisted Learning
ABSTRACT Background Feedback is an essential part of the educational process as it enriches students' learning experiences, provides information about their current performance, shows them what is lacking in achieving goals, and provides…
Sarvnaz Karimi, Jie Yin, Jiri Baum · 2015 · Computational Linguistics
In recent years, many studies have been published on data collected from social media, especially microblogs such as Twitter. However, rather few of these studies have considered evaluation methodologies that take into account the…
G. Annie Mailloux, Mazvita Chikomo, Ying Fan · 2025 · Ecography
Plant roots have been observed up to 70 m in depth – what would compel a plant to root so deeply? Earlier work shows that the climate, soil and drainage all affect rooting depth, but with conflicting results. For example, both the deepest…
Karolina Cyll, Sven Löffeler, Birgitte Carlsen et al. · 2022 · Scientific Reports
Abstract Active surveillance (AS) is standard of care for patients with low-risk prostate cancer (PCa), but its feasibility in intermediate-risk patients is controversial. We compared outcomes of low- and intermediate-risk patients managed…
Huijun Tang, Jiangbo Qian, Yangguang Liu et al. · 2022 · International Journal of Computational Intelligence Systems
Abstract Statistically significant pattern mining (SSPM) is to mine patterns with significance based on hypothesis test. Under the constraint of statistical significance, our study aims to introduce a new preference relation into high…
Ann Oakley · 2012 · Evidence & Policy
The contrasting careers of two government-sponsored commissions of inquiry in the late 1960s are the focus of this paper, which examines what can be learnt from them about the impact, or lack of impact, of such bodies on policy making. The…
Andrea Montanari, Yuchen Wu · 2024 · Information and Inference: A Journal of the IMA
Abstract We consider a class of statistical estimation problems in which we are given a random data matrix ${\boldsymbol{X}}\in{\mathbb{R}}^{n\times d}$ (and possibly some labels ${\boldsymbol{y}}\in{\mathbb{R}}^{n}$) and would like to…