Negative / Null Result ReportOpen accessSocial Sciences
Ingvild Almås, Alexander W. Cappelen, Erik Ø. Sørensen et al. · 2026 · The Quarterly Journal of Economics
Abstract This article provides the first comprehensive global evidence on people’s fairness and efficiency preferences, beliefs about the sources of inequality and the efficiency cost of redistribution, and policy attitudes toward redistribution. Using a globally harmonized consequential experiment with more than 65,000 individuals across 60 countries, we show that the source of inequality plays a substantially larger role for inequality acceptance than the efficiency cost of redistribution. At the global level, implemented inequality increases by 85% when inequality is caused by merit rather
View details →DOI: 10.1093/qje/qjag044Cited by 10 Failed Experiment ReportOpen accessAgricultural and Biological Sciences
Irene Dini · 2026 · Molecules
Fermented foods and probiotics represent complementary yet distinct components of human nutrition. Fermented foods are shaped by biochemical transformations driven by microbial metabolism, whereas probiotics are live microorganisms that may confer health benefits to the host. In both cases, bacteria, yeasts, and filamentous fungi mediate key metabolic activities that generate bioactive compounds and modulate host-microbiota interactions. During fermentation, microbial communities synthesize organic acids, peptides, exopolysaccharides, vitamins, and other metabolites that enhance food safety, s
View details →DOI: 10.3390/molecules31081353Cited by 10 Negative / Null Result ReportOpen accessMedicine
Y. Kanemitsu, Yasuhiro Shimizu, Junki Mizusawa et al. · 2026 · Journal of Clinical Oncology
JCOG0603 demonstrated improved disease-free survival (DFS) with adjuvant mFOLFOX6 after hepatectomy compared with hepatectomy alone in colorectal liver-only metastasis (CRLM), but the overall survival (OS) data were immature. Here, we…
View details →DOI: 10.1200/jco-25-01231Cited by 10 Negative / Null Result ReportOpen accessMedicine
Shabnam Santos, Ivonne Salinas, Nicolás Almeida et al. · 2025 · Engineering Microbiology
ABSTRACT Parkinson’s disease (PD) is a chronic, progressive neurodegenerative disorder characterized by debilitating motor and non-motor symptoms. Its etiology is multifactorial, with no single definitive cause identified, although aging…
View details →DOI: 10.1016/j.engmic.2025.100222Cited by 10 Negative / Null Result ReportOpen accessSocial Sciences
Shaofeng Wang, Hao Zhang · 2026 · International Journal of Educational Technology in Higher Education
Abstract The rapid integration of generative artificial intelligence (GenAI) into higher education has precipitated a critical tension between the pursuit of efficiency and the imperative for deep, transformative learning. While GenAI offers unprecedented speed in knowledge processing, it raises concerns that efficiency-driven motivations may erode the cognitive struggle essential for intellectual growth. This study investigates how Human-GenAI pedagogical partnerships influence transformative learning through the dual cognitive pathways of vigilance and offloading, moderated by efficiency ori
View details →DOI: 10.1186/s41239-026-00585-xCited by 10 Negative / Null Result ReportOpen accessPharmacology, Toxicology and Pharmaceutics
Hartmut Jaeschke, Anup Ramachandran · 2025 · Exploration of Digestive Diseases
Acetaminophen (APAP)-induced liver injury and acute liver failure is a significant clinical problem worldwide; in addition, APAP overdoses in animals or in cell culture are used as popular models to study drug-induced liver injury mechanisms and test therapeutic interventions. Early assumptions that APAP toxicity is caused by a single mechanism resulting in a defined mode of cell death in hepatocytes had to be questioned when over the years many different mechanisms and modes of cell death were reported. Although many of the contradictory results and conclusions reported over the years can be
View details →DOI: 10.37349/edd.2025.100569Cited by 10 Negative / Null Result ReportOpen accessEngineering
Teevrat Garg, Ryan Hanna, Jeff Myers et al. · 2026 · Journal of Environmental Economics and Management
Aligning electric vehicle (EV) charging with periods of abundant clean energy is essential for decarbonizing transportation. In solar-dominated grids, this requires shifting charging to midday hours – when vehicles are typically parked at workplaces. Yet workplace charging networks operate under institutional constraints such as shared infrastructure, bundled parking and charging services, and limited willingness to require drivers to move vehicles, making time-of-day pricing and active management difficult to implement. In a natural field experiment (n = 629 drivers) across a large workplace
View details →DOI: 10.1016/j.jeem.2026.103383Cited by 10 Negative / Null Result ReportOpen accessHealth Professions
Allison Kufta, Ali R. Djalilian · 2025 · Journal of Clinical Medicine
Background/Objectives: Patient education materials (PEMs) in ophthalmology often exceed recommended readability levels, limiting accessibility for many patients. While organizations like the AAO provide relatively easy-to-read resources, topics remain limited, and other associations’ PEMs are too complex. AI chatbots could help clinicians create more comprehensive, accessible PEMs to improve patient understanding. This study aims to compare the readability of patient education materials (PEMs) written by the American Academy of Ophthalmology (AAO) with those generated by large language models
View details →DOI: 10.3390/jcm14196968Cited by 10 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Mathilde Bourdon, Chloé Maignien, Marion Ouazana et al. · 2025 · Reproductive BioMedicine Online
Oestradiol plays a crucial role in reproduction, particularly in assisted reproductive technology (ART), where it can reach supraphysiological concentrations. These fluctuations occur during ovarian stimulation in fresh embryo transfer cycles and during endometrial preparation for frozen embryo transfer, potentially impacting implantation and perinatal outcomes. Oestradiol influences endometrial proliferation, receptivity, implantation and placentation, with the sensitivity of the endometrium to systemic oestrogen emerging as a key determinant of reproductive success. In fresh embryo transfer
View details →DOI: 10.1016/j.rbmo.2025.105131Cited by 10 Negative / Null Result ReportOpen accessMedicine
Jacopo Conti, Nicholas Geremia, Stefano Di Bella et al. · 2025 · European Journal of Clinical Microbiology & Infectious Diseases
PURPOSE: To describe the epidemiology, diagnosis, microbiological findings, clinical features, and outcomes of infectious spondylodiscitis (IS). METHODS: Retrospective analysis of 98 IS patients (2010-2023 - Trieste Hospital). Clinical, radiological, and microbiological data analysed, multivariate logistic regression assessed risk factors for poor outcomes. RESULTS: The incidence of IS was 3 cases per 100,000 inhabitants per year. Pyogenic infections accounted for 54% of cases, tuberculosis for 10%, while 35% remained of unknown etiology. Back pain (79%) and fever (72%) were the most common sy
View details →DOI: 10.1007/s10096-025-05292-5Cited by 10 Negative / Null Result ReportOpen accessBusiness, Management and Accounting
Jung Ho Choi, Brandon Gipper, Shawn Shi · 2025 · Review of Accounting Studies
Early empirical evidence showed a lack of relative performance evaluation (RPE) for executive pay, a surprise given its theoretical appeal. We hypothesize that executive pay transparency can enhance the monitoring of pay practices and…
View details →DOI: 10.1007/s11142-025-09880-wCited by 10 Negative / Null Result ReportOpen accessMedicine
Jiahui Xiang, Jiayi Li, Zizhao Guo et al. · 2026 · Biomarker Research
Poly (ADP-ribose) polymerase (PARP) inhibitors have emerged as a paradigm-shifting therapeutic strategy in oncology, demonstrating significant synthetic lethality in tumors characterized by homologous recombination deficiency. Due to their…
View details →DOI: 10.1186/s40364-026-00908-0Cited by 10 Negative / Null Result ReportOpen accessEnergy
Shufang Yang, Xue Lu, Jia Wang et al. · 2025 · Marine Drugs
Astaxanthin, a high-value keto-carotenoid with potent antioxidant and health-promoting properties, has gained global attention as a sustainable nutraceutical and biotechnological product. The green microalgae Haematococcus pluvialis and Chromochloris zofingiensis represent two promising natural producers, yet they differ markedly in physiology, productivity, and industrial scalability. This review provides a focused comparative analysis of these two species, emphasizing their quantitative performance differences. H. pluvialis can accumulate astaxanthin up to ~3–5% of dry biomass but typically
View details →DOI: 10.3390/md23120485Cited by 10 Negative / Null Result ReportOpen accessPhysics and Astronomy
Chris J. Willott, Yoshihisa Asada, Kartheik G. Iyer et al. · 2025 · The Astrophysical Journal
Abstract We present JWST observations of a gravitationally lensed, extremely metal-poor galaxy at redshift z = 8.203 ± 0.001 from the CANUCS survey. Based on the low oxygen to Balmer line ratios, we infer a gas-phase metallicity of 12 + log(O/H) = 6.85 (1.4% solar), making CANUCS-A370-z8-LAE one of the most metal-poor galaxies known at z > 7. The galaxy has a high H β equivalent width of 225 ± 50 Å, small half-light radius of only r hl = 3 8 − 19 + 3 pc, and high star formation rate density of 50–100 M ⊙ yr −1 kpc −2 . The galaxy shows high-equivalent-width Ly α emission with an i
View details →DOI: 10.3847/1538-4357/addf49Cited by 10 Negative / Null Result ReportOpen accessMedicine
Ewelina Młynarska, Wiktoria Lisińska, Katarzyna Hossa et al. · 2025 · Pharmaceuticals
Vitamin D, long recognized for its essential role in calcium-phosphate balance and bone health, has increasingly been identified as a pleiotropic regulator of metabolic, cardiovascular, and renal function. Deficiency of vitamin D is widespread worldwide and has been linked to a higher risk of insulin resistance, type 2 diabetes, atherosclerosis, hypertension, and chronic kidney disease. Meta-analyses suggest that each 10 nmol/L (≈4 ng/mL) increase in serum 25-hydroxyvitamin D [25(OH)D] is associated with about a 4% lower risk of type 2 diabetes, whereas other analyses indicate an approximately
View details →DOI: 10.3390/ph18101467Cited by 10 Negative / Null Result ReportOpen accessMedicine
Suli Yu, Zhen Pang, Hong Fang et al. · 2026 · Molecular Biomedicine
Ferroptosis, a regulated cell death modality driven by iron accumulation and lipid peroxidation, has emerged as a pivotal pathophysiological mechanism across a broad spectrum of cardiovascular diseases (CVDs), which remain the leading cause of global mortality. Although robust preclinical evidence indicates that modulation of ferroptosis attenuates myocardial and vascular injury, clinical translation is constrained by incomplete understanding of context-specific roles, the paucity of validated biomarkers, and the absence of targeted therapeutics with acceptable safety profiles. In this Review,
View details →DOI: 10.1186/s43556-026-00420-9Cited by 10 Replication FailureOpen accessChemistry
Ziyang Li, Huiwen Zheng, Zou Chen et al. · 2026 · Nature Communications
The family of oxiranes encompasses a variety of compounds with extensive applications across different fields. Herein, we report the development of a visible-light irradiation method using sulfinates in the presence of DABSO to form…
View details →DOI: 10.1038/s41467-026-70407-1Cited by 10 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Ashley Rich, Ziqi Li, Alessandro De Simone et al. · 2026 · Nature Physics
Amputated salamander limbs or fish fins precisely regenerate to their pre-injury size, providing a paradigm for positional memory. Although this phenomenon has been appreciated for centuries, how position-dependent cues control tissue…
View details →DOI: 10.1038/s41567-026-03426-wCited by 10 Negative / Null Result ReportOpen accessChemical Engineering
Keying Wu, Weiyan Wu, Siyuan Liu et al. · 2026 · Angewandte Chemie International Edition
ABSTRACT Nitrate electroreduction reaction (NO 3 − RR) offers a promising solution to address excessive nitrate emissions by converting them into either environmentally benign dinitrogen or useful ammonia. Bimetallic catalysts, such as…
View details →DOI: 10.1002/anie.202524218Cited by 10 Negative / Null Result ReportOpen accessPsychology
Isaac Davor, Francis Ohene Boateng, Franco Osei-Wusu et al. · 2026 · Cogent Education
This study examines the mediating and moderating role of metacognitive awareness in the relationship between self-regulated learning and mathematics achievement of university students in Ghana. Although self-regulated learning has attracted attention as a predictor of academic performance, few studies have examined how metacognitive awareness interacts with self-regulated learning to influence mathematics achievement in the Ghanaian context. A quantitative cross-sectional design was employed. Data were collected from 315 university students, representing a population of 3,240, using a structur
View details →DOI: 10.1080/2331186x.2026.2661434Cited by 10 Negative / Null Result ReportOpen accessAgricultural and Biological Sciences
Mohamed T. El‐Saadony, Ahmed Mohamed Saad, Mahmoud Zaki Sitohy et al. · 2026 · Frontiers in Immunology
Probiotics, defined as living microorganisms, are widely recognized for their ability to positively influence the gut microbiota, an effect increasingly linked to a wide array of health benefits. They are claimed to treat or prevent conditions ranging from infant colic to cardiovascular disease, respiratory infections, and certain cancers. Since the beginning of the 21st century, consumer demand for probiotic-enriched foods has risen significantly, propelled by these health assertions. The consumption of such products has been associated with the alleviation of disorders, including irritable b
View details →DOI: 10.3389/fimmu.2025.1713426Cited by 10 Negative / Null Result ReportOpen accessNursing
Hengying Chen, Jue Wang, Baohua Zheng et al. · 2024 · Lipids in Health and Disease
BACKGROUND: Exposure to different concentration levels of fatty acids (FAs) may have an impact on depression. However, previous studies using individual FAs may not reflect the performance of mixtures of various FAs, and the associations of FA patterns with depression remain unclear. METHODS: We conducted the cross-sectional analysis in 792 adults aged 18 and older with available serum FAs and depression screening data in the National Health and Nutrition Examination Survey (NHANES) 2011-2012. The serum concentrations of thirty FAs were measured using gas chromatography-mass spectrometry and t
View details →DOI: 10.1186/s12944-024-02142-9Cited by 10 Negative / Null Result ReportOpen accessMedicine
Megan L. Uhelski, Mandee K. Schaub, Felipe Espinosa et al. · 2026 · Pain
ABSTRACT: Nonselective antagonists of voltage-gated sodium channels (VGSCs) provide effective local analgesia, but systemic administration is fraught with unwanted cardiovascular and central nervous system toxicity. The development of…
View details →DOI: 10.1097/j.pain.0000000000003931Cited by 10 Replication FailureOpen accessImmunology and Microbiology
Caroline Thng, Sharareh Eskandari, Fengyi Jin et al. · 2026 · npj Vaccines
Neisseria gonorrhoeae (NG) causes significant morbidity globally, and no licensed vaccine currently exists. Observational studies suggest the four-component meningococcal B (4CMenB) vaccine may provide cross-protection against NG. We conducted MenGO, an open-label, randomized controlled trial to evaluate the efficacy, safety, and immunogenicity of 4CMenB against NG in gay and bisexual men (GBM). Participants were randomized 1:1 to receive two doses of 4CMenB, or no vaccine, and were followed for 2 years with 3-monthly visits. 4CMenB vaccination did not significantly reduce gonorrhoea incidence
View details →DOI: 10.1038/s41541-026-01422-yCited by 10 Negative / Null Result ReportOpen accessBusiness, Management and Accounting
T. Zhang, Chuan Qin, Zhaoying Lu · 2025 · International Review of Economics & Finance
This study investigates the relationship between firm-level market competitiveness and corporate environmental, social, and governance (ESG) performance, with a particular focus on the underlying mechanisms and moderating factors…
View details →DOI: 10.1016/j.iref.2025.104201Cited by 10 Negative / Null Result ReportOpen accessMedicine
A. Giordano, Cristina Romero-Mascarell, Begoña González-Suárez et al. · 2025 · Digestive Diseases and Sciences
The integration of artificial intelligence (AI) into capsule endoscopy is transforming gastrointestinal diagnostics by enhancing lesion detection and optimizing reading efficiency. This review focuses on the clinical applications of…
View details →DOI: 10.1007/s10620-025-09099-4Cited by 10 Negative / Null Result ReportOpen accessMedicine
Florian Kahles, Andreas L. Birkenfeld, Nikolaus Marx · 2026 · Journal of Clinical Investigation
The incretin hormone glucagon-like peptide-1 (GLP-1) exerts potent effects on glucose metabolism, prompting the development of therapeutic strategies that enhance activity of the GLP-1 receptor (GLP-1R) pathway. Inhibitors of dipeptidyl peptidase 4 (DPP-4) prolong the half-life of endogenous GLP-1 and typically achieve reductions in HbA1c of 0.5%-0.8%. However, large-scale cardiovascular (CV) outcomes trials (CVOTs) with DPP-4 inhibitors demonstrated CV safety but did not show a reduction in CV events. A second incretin-based therapeutic approach was the development of GLP-1R agonists (GLP-1RA
View details →DOI: 10.1172/jci194748Cited by 10 Negative / Null Result ReportOpen accessMedicine
Grzegorz K. Jakubiak, Natalia Pawlas, Monika Starzak et al. · 2026 · Vascular Health and Risk Management
Purpose: The purpose of this study was to analyze the relationship between resting high-sensitive serum cardiac troponin T concentration (hs-cTnT), D-dimer, and N-terminal pro–B-type natriuretic peptide (NT-proBNP), measured outside the…
View details →DOI: 10.2147/vhrm.s583398Cited by 10 Negative / Null Result ReportOpen accessMaterials Science
Sonakshi Gupta, Akhlak Mahmood, Shivank Shukla et al. · 2025 · Macromolecular Rapid Communications
ABSTRACT Machine learning and artificial intelligence have revolutionized polymer science by enhancing the ability to rapidly predict key polymer properties and enabling generative design. The utilization of large language models (LLMs) in polymer informatics may offers additional opportunities for advancement. Unlike traditional methods that depend on large labeled datasets, hand‐crafted representations of the materials, and complex feature engineering, LLM‐based methods utilize natural language inputs via a transfer learning process and eliminate the need for complex representation and finge
View details →DOI: 10.1002/marc.202500388Cited by 10 Negative / Null Result ReportOpen accessMedicine
Şafak Kılıç · 2025 · PLoS ONE
BACKGROUND AND OBJECTIVE: Male fertility assessment through sperm morphology analysis remains a critical component of reproductive health evaluation, as abnormal sperm morphology is strongly correlated with reduced fertility rates and poor assisted reproductive technology outcomes. Traditional manual analysis performed by embryologists is time-intensive, subjective, and prone to significant inter-observer variability, with studies reporting up to 40% disagreement between expert evaluators. This research presents a novel deep learning framework combining Convolutional Block Attention Module (CB
View details →DOI: 10.1371/journal.pone.0330914Cited by 10 