A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
19814 results in Negative / Null Result Report · page 133 of 661
JOHN LOOMIS, CATHERINE KESKE · 2011 · Contemporary Economic Policy
Outdoor recreation is a large industry that can diversify public land‐based economies that have traditionally relied upon resource extraction. However, what happens to nature‐based recreation visitor spending and benefits during times of…
Allyson L. Anding, Sofia Kinton, Kaitlyn Baranowski et al. · 2023 · Journal of Pharmacology and Experimental Therapeutics
Pompe disease is a rare glycogen storage disorder caused by a deficiency in the lysosomal enzyme acid α-glucosidase, which leads to muscle weakness, cardiac and respiratory failure, and early mortality. Alglucosidase alfa, a recombinant…
Minesh Khatri, David M. Charytan, Sam Parnia et al. · 2021 · Kidney360
Abstract Key Points Patients with ESKD had higher crude mortality rates than those without CKD, but thiswas no longer significant after multivariate adjustment. Patients with ESKD, when directly compared with those with nondialysis CKD,…
Jing Cheng, Carl Gao, Reeta Ala‐Jaakkola et al. · 2024 · JAMA Network Open
Importance: Probiotic supplementation may improve bowel movements. However, large, properly designed studies are lacking. Objective: To evaluate the potential benefit of Bifidobacterium animalis subsp lactis HN019 on constipation,…
Cecile A. Feldman, Janine Fredericks-Younger, Paul J. Desjardins et al. · 2025 · The Journal of the American Dental Association
BACKGROUND: Opioids are still being prescribed to manage acute postsurgical pain. Unnecessary opioid prescriptions can lead to addiction and death, as unused tablets are easily diverted. METHODS: To determine whether combination nonopioid analgesics are at least as good as opioid analgesics, a multisite, double-blind, randomized, stratified, noninferiority comparative effectiveness trial was conducted, which examined patient-centered outcomes after impacted mandibular third-molar extraction surgery. Participants were randomized to receive 5 mg of hydrocodone with 300 mg of acetaminophen (opioi
Ruth Horry, Neil Brewer, Nathan Weber · 2015 · Law and Human Behavior
When making a memorial judgment, respondents can regulate their accuracy by adjusting the precision, or grain size, of their responses. In many circumstances, coarse-grained responses are less informative, but more likely to be accurate,…
Rachael Slater, Kukatharmini Tharmaratnam, Salma Belnour et al. · 2024 · Sensors
The diagnosis of inflammatory bowel disease (IBD) in children and the need to distinguish between subtypes (Crohn's disease (CD) and ulcerative colitis (UC)) requires lengthy investigative and invasive procedures. Non-invasive, rapid, and cost-effective tests to support these diagnoses are needed. Faecal volatile organic compounds (VOCs) are distinctive in IBD. VOC profiles can be rapidly determined using a gas chromatography-sensor device (OdoReader©). In an inception-cohort of children presenting with suspected IBD, we directly compared the diagnostic fidelity of faecal calprotectin (FCP, a
Syed Imran Ali, Morgan C. MacDonald, J. Jincy et al. · 2011 · Journal of Water Sanitation and Hygiene for Development
This study investigated the efficacy of a POU water treatment system featuring sari-cloth filtration and/or Moringa oleifera coagulation as pre-treatments for solar disinfection (SODIS). Surface water from a peri-urban slum in Chennai,…
Haoze Wu · 2017
In this project, we aimed to improve the runtime of Minisat, a Conflict-Driven Clause Learning (CDCL) solver that solves the Propositional Boolean Satisfiability (SAT) problem. We first used a logistic regression model to predict the…
Selin Ersoydan, Derya Yakar, Ömer Kasalak et al. · 2022 · European Radiology
Abstract Objective To investigate temporal changes in clinical reasoning quality of physicians who requested abdominal CT scans at a tertiary care center during on-call hours within a 15-year period. Methods This retrospective study…
Arindam Datta, Md. Hafizur Rahman, R. Suresh · 2021 · Journal of Environmental Quality
Abstract To control the spread of COVID‐19, the government of India imposed a nationwide lockdown on all nonessential activities from 22 Mar. to 3 May 2020. Daily ambient particulate matter ≤10 μm in diameter (PM 10 ), particulate matter…
Pieter M. R. Herings, Adam H. Dyer, Seán Kennelly et al. · 2022 · Sensors
Type 2 Diabetes Mellitus (T2DM) in midlife is associated with a greater risk of dementia in later life. Both gait speed and spatiotemporal gait characteristics have been associated with later cognitive decline in community-dwelling older adults. Thus, the assessment of gait characteristics in uncomplicated midlife T2DM may be important in selecting-out those with T2DM at greatest risk of later cognitive decline. We assessed the relationship between Inertial Motion Unit (IMUs)-derived gait characteristics and cognitive function assessed via Montreal Cognitive Assessment (MoCA)/detailed neuropsy
Lilian Anderson, Charlotte Brassey, Stuart Pond et al. · 2023 · The Anatomical Record
A reversion to secondary quadrupedality is exceptionally rare in nature, yet the convergent re-evolution of this locomotor style occurred at least four separate times within Dinosauria. Facultative quadrupedality, an intermediate state between obligate bipedality and obligate quadrupedality, may have been an important transitional step in this locomotor shift, and is proposed for a range of basal ornithischians and sauropodomorphs. Advances in virtual biomechanical modeling and simulation have allowed for the investigation of limb anatomy and function in a range of extinct dinosaurian species,
Suhe Ji, Ke Li, Linfeng Zou · 2019 · 2019 International Joint Conference on Information, Media and Engineering (IJCIME)
Although the increased use of authentic materials in listening comprehension teaching has become general practice, it is crucial to find out whether or not the new technology-supported authentic material could be beneficial to English as a…
Eunkyung Choi, Minjoo Ryu, Haeri Lee et al. · 2017 · Dalton Transactions
The steric hindrance of reactants and trace water effects on transesterification catalysis using the cage coordination network have been scrutinized.
Jennifer Chun-Li Wu, Tung‐liang Chiang · 2015 · Early Child Development and Care
Low birthweight (LBW) children tend to have higher risks of developmental problems. According to differential susceptibility hypothesis, these putatively vulnerable children may also disproportionately benefit from positive environmental…
Joon Lee, Sapna Govindan, Leo Anthony Celi et al. · 2013 · World Journal of Cardiovascular Surgery
OBJECTIVE: To develop a customized short LOS (<6 days) prediction model for geriatric patients receiving cardiac surgery, using local data and a computational feature selection algorithm. DESIGN: Utilization of a machine learning algorithm in a prospectively collected STS database consisting of patients who received cardiac surgery between January 2002 and June 2011. SETTING: Urban tertiary-care center. PARTICIPANTS: Geriatric patients aged 70 years or older at the time of cardiac surgery. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Predefined morbidity and mortality events were collec
Daniel D. De Haan · 2016 · Arabic Sciences and Philosophy
Abstract This study examines a number of different answers to the question: where does Avicenna demonstrate the existence of God within the Metaphysics of the Healing ? Many interpreters have contended that there is an argument for God's…
Jeffrey C. Posnick, Brian E. Kinard · 2019 · Plastic and Reconstructive Surgery - Global Open
Background: Crowdsourcing is increasingly being used in medical research to obtain the opinion of laypeople. The investigators hypothesized that a layperson’s perception of a primary maxillary deficiency (PMD) dentofacial deformity (DFD)…
Danfeng Xu, Rong Na, Da Huang et al. · 2020 · Asian Journal of Andrology
To evaluate whether prostate volume (PV) would provide additional predictive utility to the prostate health index (phi) for predicting prostate cancer (PCa) or clinically significant prostate cancer, we designed a prospective,…
Chris Skurka, Jeff Niederdeppe, Liana B. Winett · 2020 · DOAJ (DOAJ: Directory of Open Access Journals)
Narratives can convey the need or community-level action to address social problems. Yet narratives often tell stories about specific individuals rather than the broader collectives these problems affect. Some theorists argue that individualizing collective problems inhibits audiences from recognizing upstream causes and solutions. This study tested how narrative individualization (whether a story focuses on an individual case or a larger collective) might produce trade-offs when mobilizing support for community-level policies to address childhood obesity. We also investigated whether narrativ
Abiriga Francis, O. Ongom Patrick, Rubaihayo Patrick et al. · 2020 · Journal of Plant Breeding and Crop Science
This study was conducted to determine the yield stability of advanced cowpea lines in diverse agro-ecological zones of Uganda in order to facilitate documentation requirements for national performance trials (NPT). Thirty cowpea genotypes were evaluated against six checks in three localities, over three growing seasons, making a total of 9 unique environments. The trials were laid in a 6x6 alpha lattice design with three replications and grain yield was the principal trait measured. Single-site and multi-location data were summarized using analysis of variance. Further analysis of stability wa
Charuwalee Suwatthikul, Witsarawat Chantaweesomboon, Supatra Manatrinon et al. · 2017
Recently, real-time locating system (RTLS) with centimeter accuracy using radio frequency signal is available for commercial deployment with the use of ultra-wideband (UWB) technology. One of the commercial UWB real time locating systems…
Yuh‐Feng Wang, Tzyy‐Ling Chuang, Mei‐Hua Chuang et al. · 2019 · Tzu Chi Medical Journal
OBJECTIVE: To examine the biofactors associated with bone mineral density (BMD) in southern Taiwanese adults. MATERIALS AND METHODS: The medical records of 3242 adults who underwent health examinations between June 2014 and February 2018…
Claire Goriot, James M. McQueen, Sharon Unsworth et al. · 2020 · PLoS ONE
The aim of this study was to investigate whether early-English education benefits the perception of English phonetic contrasts that are known to be perceptually confusable for Dutch native speakers, comparing Dutch pupils who were enrolled in an early-English programme at school from the age of four with pupils in a mainstream programme with English instruction from the age of 11, and English-Dutch early bilingual children. Children were 4-5-year-olds (start of primary school), 8-9-year-olds, or 11-12-year-olds (end of primary school). Children were tested on four contrasts that varied in diff
Shujie Li, Hanfang Zeng, Changjian Wang et al. · 2022 · Frontiers in Veterinary Science
Methionine hydroxy analogs (MHA) are widely used as the main sources of methionine in ruminant feed production. The purpose of this study was to explore the effect of using MHA supplements such as MHA as a salt of calcium (MHA-Ca) and…
Victoria R. Poulton, Mante S. Nieuwland · 2022 · Neurobiology of Language
Abstract Prediction-based theories of language comprehension assume that listeners predict both the meaning and phonological form of likely upcoming words. In alleged event-related potential (ERP) demonstrations of phonological prediction,…
Adnan Taş, Seyfettin Köklü, İlhami Yüksel et al. · 2011 · PubMed
BACKGROUND: Previous studies have focused on the relationship between halitosis, gastroesophageal reflux disease and Helicobacter pylori. In this study we aimed to investigate the interaction between halitosis and upper gastrointestinal…
Adrielli Tina Lopes Rego, Joshua Snell, Martijn Meeter · 2024 · PLOS Computational Biology
Although word predictability is commonly considered an important factor in reading, sophisticated accounts of predictability in theories of reading are lacking. Computational models of reading traditionally use cloze norming as a proxy of…
Xu Yan, Hon Tat Huam, Abu Bakar Sade · 2024 · Sustainability
With the rising trend toward sustainable consumption and the pivotal role of social media in the buying behavior, brands are keen to promote sustainable products through these platforms. Virtual influencers (VIs) have emerged as lower-cost…