Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Yukun Kuang, Weiping Tan, Chaohui Hu et al. · 2024 · Frontiers in Cellular and Infection Microbiology
Background: Targeted next-generation sequencing (tNGS) has become a trending tool in the field of infection diagnosis, but concerns are also raising about its performance compared with metagenomic next-generation sequencing (mNGS). This study aims to explore the clinical feasibility of a tNGS panel for respiratory tract infection diagnosis and compare it with mNGS in the same cohort of inpatients. Methods: 180 bronchoalveolar lavage fluid samples were collected and sent to two centers for mNGS and tNGS blinded tests, respectively. The concordance between pathogen reports of both methods and th
View details →DOI: 10.3389/fcimb.2024.1498512Cited by 13 Negative / Null Result ReportOpen accessMedicine
Yusuke Kamatsuki, Marie Synnøve Qvale, Kathrin Steffen et al. · 2024 · The American Journal of Sports Medicine
Background: Anterior cruciate ligament (ACL) injury is one of the most severe injuries for athletes. It is important to identify risk factors because a better understanding of injury causation can help inform athletes about risk and increase their understanding of and motivation for injury prevention. Purpose: To investigate the relationship between anatomic factors and risk for future noncontact ACL injuries. Study Design: Cohort study; Level of evidence, 2. Methods: A total of 870, excluding 9 players with a new contact ACL injury and a player with a new noncontact ACL injury just before the
View details →DOI: 10.1177/03635465241292755Cited by 13 Negative / Null Result ReportOpen accessMedicine
Bernardo G. Collaco, Syed Ali Haider, Srinivasagam Prabha et al. · 2026 · npj Digital Medicine
Agentic AI represents a promising evolution of artificial intelligence in healthcare, with systems capable of operating autonomously to achieve defined clinical goals. However, the literature lacks conceptual clarity in distinguishing AI…
View details →DOI: 10.1038/s41746-026-02517-5Cited by 13 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Zahraa S. Al-tameemi, Alejandra Rodríguez‐Verdugo · 2024 · mSystems
ABSTRACT Microbial communities are incredibly diverse. Yet, the eco-evolutionary processes originating and maintaining this diversity remain understudied. Here, we investigate the patterns of diversification for Pseudomonas putida evolving in isolation and with Acinetobacter johnsonii leaking resources used by P. putida . We experimentally evolved four experimental replicates in monoculture and co-culture for 200 generations. We observed that P. putida diversified into two distinct morphotypes that differed from their ancestor by single-point mutations. One of the most prominent mutations hit
View details →DOI: 10.1128/msystems.01053-24Cited by 13 Negative / Null Result ReportOpen accessComputer Science
Rabab Ali Abumalloh, Mehrbakhsh Nilashi, Osama Halabi et al. · 2024 · Journal of Innovation & Knowledge
Recommendation agents (RAs) have proven to be effective decision-making tools for customers, as they can boost trust and loyalty when customers shop online. They can analyse large amounts of data using machine learning algorithms and…
View details →DOI: 10.1016/j.jik.2024.100569Cited by 13 Negative / Null Result ReportOpen accessMaterials Science
Malek Msheik, Sylvain Rodat, Stéphane Abanades · 2024 · Journal of Analytical and Applied Pyrolysis
Solar methane pyrolysis in different molten media and reactor configurations was experimented to improve hydrogen production . Pure Sn, Ni 0.18 Sn 0.82 , Cu 0.45 Bi 0.55 , and KCl melts were compared at three different temperatures…
View details →DOI: 10.1016/j.jaap.2024.106756Cited by 13 Negative / Null Result ReportOpen accessSocial Sciences
Junjie Dong, Zhidan Tan, Y Zhang et al. · 2025 · BMC Psychology
BACKGROUND: With the advancement of globalization and technology, remote work has gradually become a feasible and popular work model, particularly with the rapid adoption of working from home driven by the COVID-19 pandemic. This shift not…
View details →DOI: 10.1186/s40359-025-02994-5Cited by 13 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Ignacio J. Melero‐Jiménez, Yael Sorokin, Ami Merlin et al. · 2025 · Nature Communications
Populations facing lethal environmental change can escape extinction through rapid genetic adaptation, a process known as evolutionary rescue. Despite extensive study, evolutionary rescue is largely unexplored in mutualistic communities, where it is likely constrained by the less adaptable partner. Here, we explored empirically the likelihood, population dynamics, and genetic mechanisms underpinning evolutionary rescue in an obligate mutualism involving cross-feeding of amino acids between auxotrophic Escherichia coli strains. We found that over 80% of populations overcame a severe decline whe
View details →DOI: 10.1038/s41467-025-58742-1Cited by 13 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Burooj Ghani, Vincent J. Kalkman, Bob Planqué et al. · 2025 · Scientific Reports
Animal sounds can be recognised automatically by machine learning, and this has an important role to play in biodiversity monitoring. Yet despite increasingly impressive capabilities, bioacoustic species classifiers still exhibit imbalanced performance across species and habitats, especially in complex soundscapes. In this study, we explore the effectiveness of transfer learning in large-scale bird sound classification across various conditions, including single- and multi-label scenarios, and across different model architectures such as CNNs and Transformers. Our experiments demonstrate that
View details →DOI: 10.1038/s41598-025-00996-2Cited by 13 Negative / Null Result ReportOpen accessEngineering
Lianpeng Dai, Xin Zhao, Yishan Pan et al. · 2026 · Journal of Rock Mechanics and Geotechnical Engineering
Strainburst is a type of severe dynamic hazard frequently encountered in underground excavation, involving violent rock ejection. It is caused by the release of elastic strain energy stored in the surrounding rocks. Hence, the burst energy…
View details →DOI: 10.1016/j.jrmge.2026.02.003Cited by 12 Negative / Null Result ReportOpen accessMedicine
Akram I. Ahmad, Samita Garg, Jeffrey Jacobs et al. · 2026 · JAMA Internal Medicine
Importance: Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) are known to increase the risk of retained gastric contents. High-quality data are lacking to guide periprocedure management of GLP-1 and GIP agonists. Objective: To compare the risk of clinically significant residual gastric volume (RGV) in patients who continue vs hold 1 dose of weekly or daily GLP-1 and GIP agonists prior to sedation. Design, Setting, and Participants: This randomized, single-masked clinical trial conducted at 2 large tertiary referral centers in the US included patients under
View details →DOI: 10.1001/jamainternmed.2026.0027Cited by 12 Negative / Null Result ReportOpen accessSocial Sciences
Jeremy Bowles, Kevin Croke, Horacio Larreguy et al. · 2025 · American Political Science Review
Exposure to misinformation can affect citizens’ beliefs, political preferences, and compliance with government policies. However, little is known about how to durably reduce susceptibility to misinformation, particularly in the Global South. We evaluate an intervention in South Africa that encouraged individuals to consume biweekly fact-checks—as text messages or podcasts—via WhatsApp for six months. Sustained exposure to these fact-checks induced substantial internalization of fact-checked content, while increasing participants’ ability to discern new political and health misinformation upon
View details →DOI: 10.1017/s0003055424001394Cited by 12 Negative / Null Result ReportOpen accessSocial Sciences
Eelco Harteveld, Lars Erik Berntzen, Andrej Kokkonen et al. · 2026 · European Journal of Political Research
Abstract Affective polarization (or antipathy between supporters of opposing political camps) is considered a threat to societal cohesion and democratic stability worldwide. However, causal evidence of its impact remains scarce, especially outside the United States. Our study examines the individual-level consequences of affective polarization by manipulating it in a survey experiment in nine countries (Brazil, France, Germany, Italy, Poland, Spain, Sweden, the United Kingdom, and the United States; N ≈ 18,000) and subsequently assessing the downstream consequences for social avoidance and dis
View details →DOI: 10.1017/s1475676526101273Cited by 12 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Mathieu Quinodoz, Kim Rodenburg, Zuzana Cvačková et al. · 2026 · Nature Genetics
Small nuclear RNAs (snRNAs) combine with specific proteins to generate small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. U4 snRNA forms a duplex with U6 and, together with U5, contributes to the tri-snRNP…
View details →DOI: 10.1038/s41588-025-02451-4Cited by 12 Negative / Null Result ReportOpen accessSocial Sciences
Suzanne M. Skevington, Kara Schick‐Makaroff, Christine Rowland et al. · 2024 · PLoS ONE
Gender inequalities in health-related quality of life (QoL) are generally few and small, even in large surveys. Many generic measures limit assessment to QoL overall and its physical and psychological dimensions, while overlooking internationally important environmental, social, and spiritual QoL domains. Unique cross-cultural legacy data was collected using four WHOQOL-100 surveys of adults living in 43 cultures world-wide (17,608 adults; ages 15-101). It was first used to examined gender profiles of its five QoL international domains, and their component facets. Few significant gender differ
View details →DOI: 10.1371/journal.pone.0310445Cited by 12 Negative / Null Result ReportOpen accessSocial Sciences
Marcel Garz, Märt Ots · 2025 · Journal of Communication
Abstract News organizations have been under financial pressure to streamline their activities for decades. Critics argue that this pressure undermines the quality of news, posing a severe threat to democracy. However, the effects of media consolidation on news quality are theoretically ambiguous and empirical evidence is scarce. To address this gap, we study the case of the Swedish newspaper industry between 2014 and 2022, a period where more than half of the country’s newspapers changed their owners. We collect over 2 million articles from 108 newspapers and apply state-of-the-art computation
View details →DOI: 10.1093/joc/jqae053Cited by 12 Negative / Null Result ReportOpen accessBusiness, Management and Accounting
Amina Hamdouni · 2025 · International Journal of Financial Studies
This study examines the association between Saudi banks’ internal adoption of AI-enabled FinTech-related digital tools and their financial performance, sustainability performance, and financial stability over the period 2015–2024. Using a panel dataset of 10 banks, the analysis investigates how the adoption of AI-driven technologies—such as machine-learning credit assessment, robo-advisory systems, and automated compliance tools—is related to market performance (Tobin’s Q), accounting performance (ROA and ROE), financial stability (Z-Score), and sustainability outcomes measured by both Bloombe
View details →DOI: 10.3390/ijfs13040234Cited by 12 Negative / Null Result ReportOpen accessMaterials Science
Yangjian Cai, Ming Lu, Xian Qin et al. · 2025 · Nature Communications
Shell coating is known to suppress luminescence quenching in spherical upconversion nanoparticles. However, the emergence of anisotropic nanoparticles with facet-selective, directional growth complicates the coating process, and the use of…
View details →DOI: 10.1038/s41467-025-60347-7Cited by 12 Negative / Null Result ReportOpen accessMedicine
Qiaojuan Jane Su, James R. Ashenhurst, Wanwan Xu et al. · 2026 · Nature
The development of glucagon-like peptide 1 (GLP1) receptor agonists, including semaglutide and tirzepatide, has transformed the clinical management of overweight and obesity. However, substantial inter-person variability exists in both…
View details →DOI: 10.1038/s41586-026-10330-zCited by 12 Negative / Null Result ReportOpen accessEnvironmental Science
Anwar Zahid, Md. Aminur Rahman, M. Rashidul Hassan et al. · 2026 · BRAC University Journal
The study area lies on the coastal belt of the Bengal Delta, southern Bangladesh. This study bas been condocted to deteonine salinity sources in the multi-layered aquifers of the Bengal Delta. Dissolved major ions including chloride (Cr) and brontide (Br) were measured in groundwater of the coastal areas of Bangladesh to assess the source(s) of salinity. Ionic concentrations of 48 groundwater samples were analyzed for this study; samples were collected from observation wells installed at different depths down to 336 m. The major ion trends of the upper (<200 m deep) Sodium (Na')-Chloride (C
View details →DOI: 10.64501/tg9bbj82Cited by 12 Negative / Null Result ReportOpen accessMaterials Science
Luis E. Castro-Anaya, Eduardo Marese, Jaime A. Lozano et al. · 2025 · Journal of Chemical Information and Modeling
High Resolution Image Download MS PowerPoint Slide Traditionally, designing novel materials involves exploring new compositions guided by insights from previous work, relying on a trial-and-error approach, where continuous synthesis and characterization proceed until the properties meet the improvements. This method is inefficient due to the challenges of exploring vast chemical spaces. In this study, a machine-learning-based methodology is developed to assist the design from available data in the literature, allowing us to test in silico more than 1.2 million compositions. Two databases with
View details →DOI: 10.1021/acs.jcim.4c01944Cited by 12 Negative / Null Result ReportOpen accessEngineering
Yue Cheng, Jian Wang, Mingwang Shao et al. · 2025 · Advanced Composites and Hybrid Materials
Hybrid polymer composites with carbon fillers are of great interest for applications requiring specific mechanical, electrical, and thermal properties. However, studies on hybrid polymer composite fiber (HPCF) with multiple carbon fillers…
View details →DOI: 10.1007/s42114-025-01341-xCited by 12 Negative / Null Result ReportOpen accessPhysics and Astronomy
Gonzalo Morrás, G. Pratten, P. Schmidt · 2026 · The Astrophysical Journal Letters
Abstract The observation of gravitational waves (GWs) from merging black holes and neutron stars provides a unique opportunity to discern information about their astrophysical environment. Two signatures that are considered powerful tracers to distinguish between different binary formation channels are general relativistic spin-induced orbital precession and orbital eccentricity. Both effects leave characteristic imprints in the GW signal that can be extracted from observations. To date, neither precession nor eccentricity has been confidently discerned in merging neutron star–black hole binar
View details →DOI: 10.3847/2041-8213/ae474cCited by 12 Negative / Null Result ReportOpen accessPhysics and Astronomy
Callum T. Donnan, Mark Dickinson, Anthony J. Taylor et al. · 2025 · The Astrophysical Journal
Abstract We present JWST/NIRSpec PRISM observations of three luminous ( M UV < −20) galaxies at z ∼ 10 observed with the CANDELS-Area Prism Epoch of Reionization Survey (CAPERS) Cycle 3 program. These galaxies exhibit extreme UV slopes compared to typical galaxies at z = 10. Of the three sources, two of them are a close pair (0 . ″ 22) of blue galaxies at z = 9.800 ± 0.003 and z = 9.808 ± 0.002 with UV slopes of β = −2.87 ± 0.15 and β = −2.46 ± 0.10, respectively, selected from PRIMER COSMOS NIRCam imaging. We perform spectrophotometric modeling of the galaxies, which suggests extre
View details →DOI: 10.3847/1538-4357/ae0a1fCited by 12 Negative / Null Result ReportOpen accessImmunology and Microbiology
Ali Ghasemi, Amaia Martínez-Usatorre, Yang Liu et al. · 2025 · Nature Communications
Cancer immunotherapy using dendritic cells (DC) pulsed ex vivo with tumour antigens is considered safe, but its clinical efficacy is generally modest. Here we engineer DC progenitors (DCP), which can replenish conventional type 1 DCs…
View details →DOI: 10.1038/s41467-025-64172-wCited by 12 Negative / Null Result ReportOpen accessImmunology and Microbiology
Yuliya Semenova, Ademi Yergaliyeva, Ainur Aimurziyeva et al. · 2024 · Antibiotics
BACKGROUND/OBJECTIVES: There has been a lack of a holistic approach to evaluating antibiotic consumption in Kazakhstan over the past few years using an internationally recognized methodology. Therefore, this study aimed to provide a nationwide evaluation of antibiotic consumption in Kazakhstan during the period 2019-2023. METHODS: Defined daily doses per 1000 inhabitants per day (DIDs) were calculated for systemic antibiotics (J01 code of the Anatomical Therapeutic Chemical Classification System (ATC)) following the methodology established by the Global Antimicrobial Resistance and Use Surveil
View details →DOI: 10.3390/antibiotics13121123Cited by 12 Negative / Null Result ReportOpen accessEnvironmental Science
Kasper Skytte Andersen, Kai Zhao, Alexander de Linde Agerskov et al. · 2025 · Nature Communications
Understanding species-level abundance dynamics in complex microbial communities is key to managing microbial ecosystems, yet it remains a major challenge. In wastewater treatment plants (WWTPs), the presence and abundance of…
View details →DOI: 10.1038/s41467-025-64175-7Cited by 12 Negative / Null Result ReportOpen accessMedicine
Edoardo Cipolletta, Tatiana Zverkova Sandström, D. Rozza et al. · 2026 · JAMA Internal Medicine
Importance: Gout is associated with increased cardiovascular risk. Whether achieving a target serum urate level lower than 6 mg/dL with urate-lowering treatment (ULT) would reduce cardiovascular risk in patients with gout is unknown. Objectives: To evaluate the association between achieving a serum urate treatment target lower than 6 mg/dL and cardiovascular events among patients with gout who were newly prescribed ULT. Design, Setting, and Participants: This new-user cohort study using emulated target trial framework with up to 5-year follow-up was performed using primary care data from the C
View details →DOI: 10.1001/jamainternmed.2025.7453Cited by 12 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Nikola Pavlović, Petar Todorović, Mirko Maglica et al. · 2025 · Biomolecules
The heart’s relentless contractile activity depends critically on mitochondrial function to meet its extraordinary bioenergetic demands. Mitochondria, through oxidative phosphorylation, not only supply ATP but also regulate metabolism, calcium homeostasis, and apoptotic signaling, ensuring cardiomyocyte viability and cardiac function. Mitochondrial dysfunction is a hallmark of cardiomyopathies and heart failure, characterized by impaired oxidative phosphorylation, excessive production of reactive oxygen species (ROS), dysregulated calcium handling, and disturbances in mitochondrial dynamics an
View details →DOI: 10.3390/biom15111572Cited by 12 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Leah Zuroff, Vista Farkhondeh, Riley Bove et al. · 2025 · Drugs
Despite major advances in multiple sclerosis (MS) treatment, disability accumulation independent of relapse activity remains a significant challenge. Chronic demyelination is a key driver of neurodegeneration and disease progression,…
View details →DOI: 10.1007/s40265-025-02212-xCited by 12 