Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Maria Nikogհosyan, Siras Hakobyan, Anahit Hovhannisyan et al. · 2019 · Frontiers in Genetics
Background: During last decades a number of genome-wide association studies (GWAS) has identified numerous single nucleotide polymorphisms (SNPs) associated with different complex diseases. However, associations reported in one population are often conflicting and did not replicate when studied in other populations. One of the reasons could be that most of GWAS employ case-control design in one or a limited number of populations, but little attention was paid to global distribution of disease associated alleles across different populations. Moreover, the majority of GWAS have been performed on
View details →DOI: 10.3389/fgene.2019.00394Cited by 13 Negative / Null Result ReportOpen accessNeuroscience
Shao-Chin Hung, Aaron R. Seitz · 2011 · PLoS ONE
Consolidation, a process that stabilizes memory trace after initial acquisition, has been studied for over a century. A number of studies have shown that a skill or memory must be consolidated after acquisition so that it becomes resistant to interference from new information. Previous research found that training on a peripheral 3-dot hyperacuity task could retrogradely interfere with earlier training on the same task but with a mirrored stimulus configuration. However, a recent study failed to replicate this finding. Here we address the controversy by replicating both patterns of results, ho
View details →DOI: 10.1371/journal.pone.0024556Cited by 13 Negative / Null Result ReportOpen accessPhysics and Astronomy
Chuneeta D. Nunhokee, Donald M. Null, Cathryn M. Trott et al. · 2025 · The Astrophysical Journal
Abstract This paper presents the spherically averaged 21 cm power spectrum derived from Epoch of Reionization (EoR) observations conducted with the Murchison Widefield Array (MWA). The analysis uses EoR0-field data, centered at (R.A. = 0 h , decl. = −27 ∘ ), collected between 2013 and 2023. Building on the improved methodology described in C. M. Trott et al. (2024), we incorporate additional data quality control techniques introduced in C. D. Nunhokee (2020). We report the lowest-power-level limits on the EoR power spectrum at redshifts z = 6.5, z = 6.8, and z = 7.0. These power levels, measur
View details →DOI: 10.3847/1538-4357/adda45Cited by 13 Negative / Null Result ReportOpen accessComputer Science
Remita Austin, R. Parvathi · 2025 · Scientific Reports
The absence of reliable early treatment serves as one of the main causes of cervical cancer. Hence, it is crucial to detect cervical cancer early. The biggest challenge in diagnosing cervical cancer early is that it is asymptomatic until it develops into invasive carcinoma. In medical applications, the use of machine learning and deep learning is successful as a classifier in the preliminary identification of cancerous cells in the cervical region. In our study, we present a CNN-based method for the classification of cervical cancer cells. We present a method for accurately classifying Pap sme
View details →DOI: 10.1038/s41598-025-10009-xCited by 13 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Burooj Ghani, Vincent J. Kalkman, Bob Planqué et al. · 2025 · Scientific Reports
Animal sounds can be recognised automatically by machine learning, and this has an important role to play in biodiversity monitoring. Yet despite increasingly impressive capabilities, bioacoustic species classifiers still exhibit imbalanced performance across species and habitats, especially in complex soundscapes. In this study, we explore the effectiveness of transfer learning in large-scale bird sound classification across various conditions, including single- and multi-label scenarios, and across different model architectures such as CNNs and Transformers. Our experiments demonstrate that
View details →DOI: 10.1038/s41598-025-00996-2Cited by 13 Negative / Null Result ReportOpen accessEarth and Planetary Sciences
Xavier A. Jenkins, Roger Benson, David P. Ford et al. · 2025 · Peer Community Journal
Living reptiles include more than 20,000 species with disparate ecologies. Direct anatomical evidence from Neodiapsida, which includes the reptile crown-group and its closest extinct relatives, shows that this diversity originates from a single common ancestor that lived over 255 million years ago in the Paleozoic. However, the evolutionary assembly of crown reptile traits is poorly understood due to the lack of anatomically close relatives of Neodiapsida. We present a substantially revised phylogenetic hypothesis, informed by new anatomical data from high-resolution synchrotron tomography of
View details →DOI: 10.24072/pcjournal.620Cited by 13 Negative / Null Result ReportOpen accessSocial Sciences
Kate Ambler, Kelly Jones, Michael O’Sullivan · 2025 · Journal of Development Economics
We conduct a randomized controlled trial to test a novel intervention for increasing women’s empowerment in Uganda. The intervention includes a within-household transfer of a productive asset, which has a lower cost than an external…
View details →DOI: 10.1016/j.jdeveco.2025.103575Cited by 13 Negative / Null Result ReportOpen accessMedicine
Daniel I. McIsaac, Susan M. Lee, Dean Fergusson et al. · 2025 · JAMA Surgery
Importance: Explanatory trials suggest that prehabilitation has efficacy in improving surgical outcomes. The effectiveness of offering home-based prehabilitation across multiple centers and for older adults with frailty remains unknown. Objective: To evaluate the effectiveness of offering coach-supported, home-based prehabilitation to older surgical patients with frailty. Design, Setting, and Participants: This study is a pragmatic, parallel-arm, multicenter randomized clinical trial with embedded qualitative assessment. Clinicians and assessors were fully blinded; participants were partially
View details →DOI: 10.1001/jamasurg.2025.5288Cited by 13 Negative / Null Result ReportOpen accessMedicine
Tanayott Thaweethai, Sarah E. Donohue, Jeffrey N. Martin et al. · 2025 · Nature Communications
Longitudinal trajectories of Long COVID remain ill-defined, yet are critically needed to advance clinical trials, patient care, and public health initiatives for millions of individuals with this condition. Long COVID trajectories were…
View details →DOI: 10.1038/s41467-025-65239-4Cited by 13 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Yukun Kuang, Weiping Tan, Chaohui Hu et al. · 2024 · Frontiers in Cellular and Infection Microbiology
Background: Targeted next-generation sequencing (tNGS) has become a trending tool in the field of infection diagnosis, but concerns are also raising about its performance compared with metagenomic next-generation sequencing (mNGS). This study aims to explore the clinical feasibility of a tNGS panel for respiratory tract infection diagnosis and compare it with mNGS in the same cohort of inpatients. Methods: 180 bronchoalveolar lavage fluid samples were collected and sent to two centers for mNGS and tNGS blinded tests, respectively. The concordance between pathogen reports of both methods and th
View details →DOI: 10.3389/fcimb.2024.1498512Cited by 13 Negative / Null Result ReportOpen accessMaterials Science
Dylan M. Anstine, Qiyuan Zhao, R.I. Zubatyuk et al. · 2026 · Science Advances
Mechanistic modeling of chemical transformations offers a compelling basis for understanding reactivity and allows for prediction of reaction outcomes before attempting experiments. Despite progress in machine-learned interatomic…
View details →DOI: 10.1126/sciadv.aea1557Cited by 13 Negative / Null Result ReportOpen accessMathematics
Changye Wu, Pierre Pudlo, Christian P. Robert et al. · 2026 · Statistics and Computing
stands for empirical, leverages importance sampling to construct an empirical distribution on discretization parameters, thereby eliminating the need for manual burn-in diagnostics and online adaptation. The proposal distribution used in the calibration stage is obtained via a Population Monte Carlo scheme with tempering and relies on flexible parametric variational families such as normalizing flows. Once the calibration stage complete, the resulting algorithm defines a homogeneous Markov chain via a mixture of HMC kernels with a fixed mixing distribution, and hence preserves the target distr
View details →DOI: 10.1007/s11222-026-10972-zCited by 13 Negative / Null Result ReportOpen accessMedicine
Timo F. W. Soeterik, Joris G. Heetman, Rick Hermsen et al. · 2024 · European Urology Oncology
BACKGROUND AND OBJECTIVE: The role of prostate-specific membrane antigen (PSMA)-based positron emission tomography (PET)/computed tomography (CT) in addition to magnetic resonance imaging (MRI) for local staging of prostate cancer (PC) has been poorly addressed so far. Our aim was to assess the diagnostic accuracy of PSMA PET/CT and MRI, alone and combined, for detection of extraprostatic extension (EPE) and seminal vesicle invasion (SVI) in PC. METHODS: We conducted a multicenter retrospective study evaluating patients undergoing PSMA PET/CT and MRI before radical prostatectomy. The sensitivi
View details →DOI: 10.1016/j.euo.2024.11.002Cited by 13 Negative / Null Result ReportOpen accessNeuroscience
Thomas Cope, Manon Grube, Arnab Mandal et al. · 2014 · Neuropsychologia
Bilateral, high-frequency stimulation of the basal ganglia (STN-DBS) is in widespread use for the treatment of the motor symptoms of Parkinson׳s disease (PD). We present here the first psychophysical investigation of the effect of STN-DBS upon perceptual timing in the hundreds of milliseconds range, with both duration-based (absolute) and beat-based (relative) tasks; 13 patients with PD were assessed with their STN-DBS 'on', 'off', and then 'on' again. Paired parametric analyses revealed no statistically significant differences for any task according to DBS status. We demonstrate, from the exa
View details →DOI: 10.1016/j.neuropsychologia.2014.02.021Cited by 13 Negative / Null Result ReportOpen accessNeuroscience
Anne Krogh Nøhr, Morten Lindow, Annika Forsingdal et al. · 2021 · Neuropsychopharmacology
A better understanding of the biological factors underlying antidepressant treatment in patients with major depressive disorder (MDD) is needed. We perform gene expression analyses and explore sources of variability in peripheral blood related to antidepressant treatment and treatment response in patients suffering from recurrent MDD at baseline and after 8 weeks of treatment. The study includes 281 patients, which were randomized to 8 weeks of treatment with vortioxetine (N = 184) or placebo (N = 97). To our knowledge, this is the largest dataset including both gene expression in blood and pl
View details →DOI: 10.1038/s41386-021-01002-9Cited by 13 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Stella Aslibekyan, Hassan S. Dashti, Toshiko Tanaka et al. · 2014 · Chronobiology International
Sunlight exposure has been shown to alter DNA methylation patterns across several human cell-types, including T-lymphocytes. Since epigenetic changes establish gene expression profiles, changes in DNA methylation induced by sunlight…
View details →DOI: 10.3109/07420528.2014.944266Cited by 13 Negative / Null Result ReportOpen accessEconomics, Econometrics and Finance
Xi Wang, Tao Pei, Ci Song et al. · 2023 · Sustainable Cities and Society
Quantifying the centrality of places and identifying centers constitute the basis for assessing the urban spatial structure, which is essential for sustainable spatial planning. Both the existence and intensity of linkages contribute to…
View details →DOI: 10.1016/j.scs.2023.104984Cited by 13 Negative / Null Result ReportOpen accessSocial Sciences
Penny Holding, Amina Abubakar, Elizabeth Obiero et al. · 2011
The aim of this paper is to describe the adaptations made to the Infant-Toddler version of the Home Observation Measure of the Environment for use in a low income Kenyan population. A total of 425 (214 girls) children aged 6-35 months were…
View details →DOI: 10.4087/ngnw9101Cited by 13 Negative / Null Result ReportOpen accessNeuroscience
Klaus Oberauer · 2022 · Psychological Science
Some theorists argue that working memory is limited to a discrete number of items and that additional items are not encoded at all. Adam et al. (2017) presented evidence supporting this hypothesis: Participants reproduced visual features of up to six items in a self-chosen order. After the third or fourth response, error distributions were indistinguishable from guessing. I present four experiments with young adults (each N = 24) reexamining this finding. Experiment 1 presented items slowly and sequentially. Experiment 2 presented them simultaneously but longer than in the experiments of Adam
View details →DOI: 10.1177/09567976211068045Cited by 13 Negative / Null Result ReportBiochemistry, Genetics and Molecular Biology
Luca‐Cesare Blawitzki, Nina Bartels, Lorand Bonda et al. · 2024 · Biomacromolecules
The glycocalyx, a complex carbohydrate layer on cell surfaces, plays a crucial role in various biological processes. Understanding native glycocalyces' complexity is challenging due to their intricate and dynamic nature. Simplified mimics…
View details →DOI: 10.1021/acs.biomac.4c00646Cited by 13 Negative / Null Result ReportOpen accessBusiness, Management and Accounting
Hima Bindu Kota, Ramanjeet Singh · 2016 · Serbian Journal of Management
Family businesses are fundamental to nation building as they contribute towards the GDP of any country and are also major employment creators. Therefore, family business management is an emerging area of academic interest. In this regard, comparison between family and non-family businesses has become an important area of research. The present study analyses the performance of Indian family businesses in comparison to non-family business for firms listed on BSE 500 Index for a period of 11 years from 2005-2015. Any firm with 40% or more promoter or promoter group holding has been identified as
View details →DOI: 10.5937/sjm11-9165Cited by 13 Negative / Null Result ReportOpen accessMedicine
Zhe Wang, Xiaoli Xie, Jinglu Zhao et al. · 2018 · Bioscience Reports
Biliary atresia (BA) is a multifactorial pathogenic disease with possible genetic components. As a member of membrane skeletal proteins in the liver and bile ducts, a haplotype composed by five single nucleotide polymorphisms (SNPs) on adducin 3 (ADD3) has been identified as associated with BA. However, limited study was designed to further elaborate the mutual relationship amongst those replicated SNPs to disease. We selected three susceptibility SNPs in ADD3 and conducted a replication study using 510 BA cases and 1473 controls to evaluate the individual function of the SNPs and further stra
View details →DOI: 10.1042/bsr20171688Cited by 13 Negative / Null Result ReportPsychology
Olga Perepelkina, Maria Boboleva, Галина Арина et al. · 2017 · Multisensory Research
The aim of the study was to investigate how emotion information processing factors, such as alexithymia and emotional intelligence, modulate body ownership and influence multisensory integration during the ‘rubber hand illusion’ (RHI)…
View details →DOI: 10.1163/22134808-00002577Cited by 13 Negative / Null Result ReportOpen accessPsychology
Hanno Andreas Ohmann, Niclas Kuper, Jan Wacker · 2022 · PLoS ONE
The Effort-Expenditure for Rewards Task (EEfRT) has gained validity evidence from several studies. However, various modifications have been applied to the original version, which have never been compared systematically. In Study 1, we tested 120 healthy participants to directly compare two versions of the EEfRT. In Study 2, we tested a larger sample of 394 healthy participants to further examine the original EEfRT. We replicated the split-half reliability of both task versions. However, self-reported personality traits (e.g., trait BAS) correlated with only some task performance parameters in
View details →DOI: 10.1371/journal.pone.0262902Cited by 13 Negative / Null Result ReportOpen accessNeuroscience
Kelly L. Whiteford, Lucas S. Baltzell, Matt Chiu et al. · 2025 · Nature Communications
Musical training has been reported to be associated with enhanced neural processing of sounds, as measured via the frequency following response (FFR), implying the potential for human subcortical neural plasticity. We conducted a…
View details →DOI: 10.1038/s41467-025-62155-5Cited by 13 Negative / Null Result ReportSocial Sciences
Branden B. Johnson, Marcus Mayorga · 2020 · Human and Ecological Risk Assessment An International Journal
Cross-sectional surveys, despite their value, are unable to probe dynamics of risk perceptions over time. An earlier longitudinal panel study of Americans’ views on Ebola risk inspired this partial replication on Americans’ views of Zika…
View details →DOI: 10.1080/10807039.2020.1820852Cited by 13 Negative / Null Result ReportOpen accessNeuroscience
Kaiwen Cheng, Aolin Ding, Lianfang Jiang et al. · 2019 · Frontiers in Human Neuroscience
Previous studies have demonstrated the automatic vigilance effect for faces and pictures and have attributed it to the brain's prioritized unconscious evaluation of early evolutionary stimuli that are critical to survival. Whether this effect exists for evolutionarily more recent stimuli, such as written words, has become the center of much debate. Apparently contradicting results have been reported in different languages, such as Hebrew, English, and Traditional Chinese (TC), with regard to the unconscious processing of emotional words in breaking continuous flash suppression (b-CFS). Our cur
View details →DOI: 10.3389/fnhum.2019.00309Cited by 13 Negative / Null Result ReportOpen accessComputer Science
Sun Kyong Lee, Hyunjin Park, Seoyoung C. Kim · 2024 · Behaviour and Information Technology
This study investigated the impact of task types (functional vs. social) and the gendered voices (female vs. male) of Siri, an intelligent virtual assistant (IVA), on social presence and trust perceptions toward the IVA.In an online…
View details →DOI: 10.1080/0144929x.2024.2306136Cited by 13 Negative / Null Result Report
Martin S. Davey, Eoghan T. Hurley, Tom R. Doyle et al. · 2022 · The American Journal of Sports Medicine
Background: Debate centering on the management of anterior shoulder instability (ASI) in recent years has led to many randomized controlled trials (RCTs) being published on the topic. The fragility index (FI) has subsequently emerged as a…
View details →DOI: 10.1177/03635465221077268Cited by 13 Negative / Null Result ReportOpen accessEngineering
Khuzairi Masrakin, Hasliza A. Rahim, Ping Jack Soh et al. · 2019 · IEEE Access
This paper presents the assessment of short-term wireless body area network (WBAN) exposure, which is operated at the industrial, scientific, and medical (ISM) band (2.45 GHz) in the vicinity of the human body. The experiment utilizes two popular textile antenna topologies, a planar monopole and a patch antenna as the radiating sources. The objective of this experiment is to investigate whether the exposure from WBAN may influence the physiological parameters (body temperature, blood pressure, and heart rate) and the well-being of the wearer. Counter-balanced, crossover, and the single-blind m
View details →DOI: 10.1109/access.2019.2928343Cited by 13 