A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
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Qiang Liu, Kevin K. Lin, Bogi Andersen et al. · 2010 · Bioinformatics
Abstract Motivation: Time-course gene expression datasets provide important insights into dynamic aspects of biological processes, such as circadian rhythms, cell cycle and organ development. In a typical microarray time-course experiment,…
Daniel M. Goldenholz, Celena Eccleston, Robert Moss et al. · 2024 · Epilepsia
OBJECTIVE: Recently, a deep learning artificial intelligence (AI) model forecasted seizure risk using retrospective seizure diaries with higher accuracy than random forecasts. The present study sought to prospectively evaluate the same…
Orekoya Adedapo, Norbert Boros, Anna Boglárka Dálnoki et al. · 2024 · Discover Sustainability
Abstract The research examined the ability of each treatment to recover a known quantity of particles and the impact on identifying polymer type using a microscope. By conducting extensive research on the changes induced in the chemical…
Anca Jivănescu, Adrian Bara, Andrei-Bogdan Faur et al. · 2021 · Applied Sciences
Is the accuracy of the older generation of IOSs an impediment for obtaining a quality intraoral digital impression? The aim of this study was to evaluate the differences in accuracy between four intraoral scanners (two of the latest IOSs…
Eyüp Özkan, Aslan Erdoğan, Ali Karagöz et al. · 2023 · Angiology
This study compared the predictive power of the systemic immune-inflammation index (SII) and Naples prognostic score (NPS) in determining the severity of coronary artery disease (CAD). The study included 1138 patients who underwent…
Jekaterina Kazantseva, Roman Ivanov, Michael Gasik et al. · 2016 · Scientific Reports
Abstract Three-dimensional (3D) customized scaffolds capable to mimic a native extracellular matrix open new frontiers in cells manipulation and advanced therapy. The major challenge is in a proper substrate for in vitro models on…
Endre Willassen, Jon-Ivar Westgaard, Jon Anders Kongsrud et al. · 2022 · PeerJ
To protect and restore ecosystems and biodiversity is one of the 10 challenges identified by the United Nations’s Decade of the Ocean Science. In this study we used eDNA from sediments collected in two fjords of the Svalbard archipelago…
Bente Silnes Tandberg, Kathrine Frey Frøslie, Trond Markestad et al. · 2019 · Acta Paediatrica
Abstract Aim The aim was to compare growth in very premature infants cared for in a single‐family room (SFR) and an open‐bay (OB) unit. We recorded duration of parental presence and skin‐to‐skin contact as proxies for parental involvement…
Carolina Diller, Miguel Castañeda-Zárate, Steven D. Johnson · 2019 · Biology Letters
Bird pollination systems are dominated by specialist nectarivores, such as hummingbirds in the Americas and sunbirds in Africa. Opportunistic (generalist) avian nectarivores such as orioles, weavers and bulbuls have also been implicated as…
Kohei Ohnishi, Yuma Ono, Tatsuya Nomura et al. · 2014 · Scientific Reports
Abstract The combination between the spin-dependent and super-conducting (SC) transports is expected to provide intriguing properties such as crossed Andreev reflection and spin-triplet superconductivity. This may be able to open a new…
Martin Grosse Holtforth, David Altenstein, Emily Ansell et al. · 2011 · Journal of Clinical Psychology
Abstract Whereas previous interpersonal research in depression has frequently used self‐reports, patients' impact on others is rarely analyzed. We analyzed impacts of 180 depressed psychotherapy outpatients out of 832 diagnostically…
Michael K. Urban, Kristy M. Labib, Shane C. Reid et al. · 2018 · HSS Journal®: The Musculoskeletal Journal of Hospital for Special Surgery
Background The treatment of postoperative pain is a challenge after posterior spinal fusions. Pain management using predominantly opioids is often associated with multiple adverse effects, while multimodal postoperative analgesia may…
Attila Salamon, Stefania Uccheddu, Melitta Csepregi et al. · 2023 · Scientific Reports
Abstract The dog is a so far unique species to study interspecific communication and a promising evolutionary model for preverbal human communication. Recently cats were reported to show some similar skills to dogs. Here we directly…
Nicholas S. OSCROFT, Ian E. SMITH · 2010 · Respirology
ABSTRACT Background and objective: Volume‐assured non‐invasive positive pressure ventilation (va‐NIPPV) is a novel mode designed to adapt pressure support (PS) to achieve a target minute ventilation (TgV). This may optimize ventilation;…
K. C. Yates, B. S. Bauer, S. Fuelling et al. · 2019 · Physics of Plasmas
We report the first observation of a significant change in plasma formation and evolution caused by a small change in the material composition (metal alloy). Thick copper rod alloys were varied in the initial diameter from 0.5 mm to 1.59…
Nikola Hrabovska, Erik Kajati, Iveta Zolotova · 2023 · Electronics
This research article presents an analysis of health data collected from wearable devices, aiming to uncover the practical applications and implications of such analyses in personalized healthcare. The study explores insights derived from…
Penghao Ye, Senmao Xia, Yu Xiong et al. · 2020 · International Journal of Environmental Research and Public Health
Thermal power generation based on coal-fired power plants has the advantages of stability and controllability and has been the largest source of electricity supply in China. Coal-fired power plants, however, are also accompanied by high…
Jing Li, YUE-YIN PAN, Ying Zhang · 2012 · Oncology Letters
Sorafenib is a highly selective multi-targeted agent and has been reported to have potent antitumor effects against various tumors, including human non-small cell lung cancer (NSCLC). In the present study, we explored the antitumor effect…
Shao-rui Hao, Yan Ren, Shan-yan Zhang et al. · 2020 · Journal of Zhejiang University SCIENCE B
BACKGROUND: Currently, there are no drugs that have been proven to be effective against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Because of its broad antiviral activity, interferon (IFN) should be evaluated as a…
Suresh S. Ramalingam, Judy Foster, William E. Gooding et al. · 2010 · Cancer
BACKGROUND: Patients with extensive stage small cell lung cancer (SCLC) who develop disease progression with standard cisplatin-based therapy are reported to have a poor overall prognosis. Irinotecan and paclitaxel are active as single…
Jae Hong Park, Isabelle Rivière, Xiuyan Wang et al. · 2017 · Journal of Clinical Oncology
7008 Background: CD19-specific chimeric antigen receptor (CAR) T cells have demonstrated high initial responses in patients with relapsed B-ALL. However, clinical characteristics associated with the durability of response remain undefined.…
Jayastu Senapati, Sanam Loghavi, Guillermo Garcia‐Manero et al. · 2024 · Haematologica
In myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) with TP53 aberrations, dissecting the interaction amongst patient, disease and treatment factors are important for therapeutic decisions and prognostication. This…
Lukas Koedijk, Ana Oprescu · 2022
The EU Green Deal mirrors the societal concern regarding climate change. In the software industry this means reducing the energy consumption of a program. This can be done by looking both at the hardware and the software used. We take a…
Laila Kristoffersen, Ragnhild Støen, Håkon Bergseng et al. · 2019 · Acta Paediatrica
Abstract Aim We compared the pain relieving effect of skin‐to‐skin contact versus standard care in the incubator during screening for retinopathy of prematurity. Methods This randomised crossover study included 35 preterm infants of less…
Botao Ning, Sheng Ye, Yi Lyu et al. · 2020 · Translational Pediatrics
BACKGROUND: Sepsis has always been a challenge in pediatric intensive care unit (PICU) with poor prognosis. In order to evaluate the effect between routine continuous renal replacement therapy (CRRT) and high-volume hemofiltration (HVHF)…
Sarita Depani, Kondwani Joseph Banda, Simon Bailey et al. · 2015 · Pediatric Blood & Cancer
BACKGROUND: We previously reported a 28-day treatment protocol for children with endemic Burkitt lymphoma (BL) which included four doses of cyclophosphamide (CPM), intrathecal methotrexate and hydrocortisone (IT MTX/HC) at Queen Elizabeth…
Aerlyn G. Dawn, Naomi Lawrence · 2013 · Dermatologic Surgery
BACKGROUND: Squamous cell carcinomas (SCCs) generally have been reported to be more prevalent on the lips than basal cell carcinomas (BCCs), but in our experience, BCCs of the lips are common, particularly in women. OBJECTIVES: To…
Jie Wu, Jianan Ren, Qinjie Liu et al. · 2019 · Frontiers in Immunology
Background: Continuous veno–venous hemofiltration (CVVH) could influence immunomodulation by cytokine removal. Damage-associated molecular patterns (DAMPs) are released by injured cells and have roles in sepsis. We investigated if the magnitude of DAMPs removal was associated with mortality in patients with sepsis undergoing CVVH. Methods: We conducted a prospective, observational study on patients acquiring CVVH at department of surgery, Jinling Hospital. Circulating levels of DAMPs (mitochondrial DNA [mtDNA]; nuclear DNA [nDNA]; heat shock protein [HSP]70) and cytokines were measured at the
Joseph T. Yun, Brittany R. L. Duff, Patrick Vargas et al. · 2019 · Psychology & Marketing
Abstract Cause‐related marketing (CRM) refers to the phenomenon where brands partner with causes, such as nonprofit organizations. Consumers may see some CRM partnerships as less compatible than others, however the level of perceived…
Moonkyoo Kong, Yu Jin Lim, Youngkyong Kim · 2018 · PubMed
Background: We conducted this study to contribute to resolving some controversial issues on management of nasopharyngeal carcinoma. Methods: Thirty-two patients with stage III-IVB nasopharyngeal carcinoma were included in this…