Negative / Null Result ReportMedicine
Jens‐Ulrik Stæhr Jensen, Lars Hein, Bettina Lundgren et al. · 2011 · Critical Care Medicine
OBJECTIVE: For patients in intensive care units, sepsis is a common and potentially deadly complication and prompt initiation of appropriate antimicrobial therapy improves prognosis. The objective of this trial was to determine whether a…
View details →DOI: 10.1097/ccm.0b013e31821e8791Cited by 358 Negative / Null Result ReportOpen accessMedicine
Lawrence Fisher, Russell E. Glasgow, Lisa A. Strycker · 2010 · Diabetes Care
OBJECTIVE: To clarify previous findings that diabetes distress is related to glycemic control and self-management whereas measures of depression are not, using both binary and continuous measures of depression. RESEARCH DESIGN AND METHODS:…
View details →DOI: 10.2337/dc09-2175Cited by 357 Negative / Null Result ReportOpen accessSocial Sciences
Yee Mei Heong, Widad Othman, Jailani Yunos et al. · 2011 · International Journal of Social Science and Humanity
Higher order thinking skills is an important aspect in teaching and learning especially at higher education institutions. Thinking skills practices are part of the generic skills that should be infused in all technical subjects. Students…
View details →DOI: 10.7763/ijssh.2011.v1.20Cited by 357 Negative / Null Result ReportOpen accessMedicine
Alessandro Doria, Andrzej T. Gałecki, Cathie Spino et al. · 2020 · New England Journal of Medicine
BACKGROUND: Higher serum urate levels are associated with an increased risk of diabetic kidney disease. Lowering of the serum urate level with allopurinol may slow the decrease in the glomerular filtration rate (GFR) in persons with type 1…
View details →DOI: 10.1056/nejmoa1916624Cited by 357 Negative / Null Result ReportEconomics, Econometrics and Finance
Manuela Angelucci, Dean Karlan, Jonathan Zinman · 2015 · American Economic Journal Applied Economics
We use a clustered randomized trial, and over 16,000 household surveys, to estimate impacts at the community level from a group lending expansion at 110 percent APR by the largest microlender in Mexico. We find no evidence of…
View details →DOI: 10.1257/app.20130537Cited by 356 Negative / Null Result ReportOpen accessEngineering
Ahmad El-Kharouf, Thomas J. Mason, Dan J. L. Brett et al. · 2012 · Journal of Power Sources
This paper presents the first part of a complete ex-situ characterisation of a wide range of commercial Gas Diffusion Layers (GDLs) used in low temperature and high temperature Proton Exchange Membrane (PEM) fuel cells. Physical and electrical characteristics of the GDLs are reported. The results show that the substrate structure has a significant effect on the mechanical and electrical properties of the GDL. Moreover, the Micro Porous Layer (MPL) structure determines the roughness of the surface, and affects the permeability and porosity of the GDL. It was found that the substrate treatment w
View details →DOI: 10.1016/j.jpowsour.2012.06.099Cited by 356 Negative / Null Result ReportOpen accessMedicine
James Y. Lau, Yuanyuan Yu, Raymond S. Tang et al. · 2020 · New England Journal of Medicine
BACKGROUND: It is recommended that patients with acute upper gastrointestinal bleeding undergo endoscopy within 24 hours after gastroenterologic consultation. The role of endoscopy performed within time frames shorter than 24 hours has not…
View details →DOI: 10.1056/nejmoa1912484Cited by 355 Negative / Null Result ReportNeuroscience
Brian A. Boyd, Grace T. Baranek, John Sideris et al. · 2010 · Autism Research
This study combined parent and observational measures to examine the association between aberrant sensory features and restricted, repetitive behaviors in children with autism (N=67) and those with developmental delays (N=42). Confirmatory…
View details →DOI: 10.1002/aur.124Cited by 355 Negative / Null Result ReportEconomics, Econometrics and Finance
Eric T. Swanson · 2011 · Brookings Papers on Economic Activity
This paper undertakes a modern event-study analysis of Operation Twist and uses its estimated effects to assess what should be expected for the recent policy of quantitative easing by the Federal Reserve, dubbed “QE2.” The paper first…
View details →DOI: 10.1353/eca.2011.0006Cited by 355 Negative / Null Result ReportEconomics, Econometrics and Finance
Dion Bongaerts, De Jong, FCJM, Driessen, JJAG · 2011 · EUR Research Repository (Erasmus University Rotterdam)
We derive an equilibrium asset pricing model incorporating liquidity risk, derivative assets, and short-selling due to hedging of non-traded risk. We show that, both for positive-net-supply assets and derivatives, the sign of liquidity…
View details →DOI: 10.1111/j.1540-6261.2010.01630.xCited by 354 Negative / Null Result ReportBusiness, Management and Accounting
Bruno Cassiman, Giovanni Valentini · 2015 · Strategic Management Journal
One novel implication of the open innovation paradigm is that inflows and outflows of knowledge are complementary. We argue that engaging simultaneously in buying and selling knowledge should allow firms to increase innovation outcomes. At…
View details →DOI: 10.1002/smj.2375Cited by 354 Negative / Null Result ReportOpen accessAgricultural and Biological Sciences
Thomas Wicker, Heidrun Gundlach, M. Spannagl et al. · 2018 · Genome biology
BACKGROUND: Transposable elements (TEs) are major components of large plant genomes and main drivers of genome evolution. The most recent assembly of hexaploid bread wheat recovered the highly repetitive TE space in an almost complete chromosomal context and enabled a detailed view into the dynamics of TEs in the A, B, and D subgenomes. RESULTS: The overall TE content is very similar between the A, B, and D subgenomes, although we find no evidence for bursts of TE amplification after the polyploidization events. Despite the near-complete turnover of TEs since the subgenome lineages diverged fr
View details →DOI: 10.1186/s13059-018-1479-0Cited by 354 Negative / Null Result ReportOpen accessEnvironmental Science
Pieter T. J. Johnson, David W. Thieltges · 2010 · Journal of Experimental Biology
Growing interest in ecology has recently focused on the hypothesis that community diversity can mediate infection levels and disease ('dilution effect'). In turn, biodiversity loss--a widespread consequence of environmental change--can…
View details →DOI: 10.1242/jeb.037721Cited by 353 Negative / Null Result ReportOpen accessSocial Sciences
Emily Corner, Paul Gill · 2014 · Law and Human Behavior
We test whether significant differences in mental illness exist in a matched sample of lone- and group-based terrorists. We then test whether there are distinct behavioral differences between lone-actor terrorists with and without mental…
View details →DOI: 10.1037/lhb0000102Cited by 353 Negative / Null Result ReportNeuroscience
Rebecca Landa, Katherine C. Holman, Allison H. O’Neill et al. · 2010 · Journal of Child Psychology and Psychiatry
BACKGROUND: Social and communication impairments are core deficits and prognostic indicators of autism. We evaluated the impact of supplementing a comprehensive intervention with a curriculum targeting socially synchronous behavior on…
View details →DOI: 10.1111/j.1469-7610.2010.02288.xCited by 352 Negative / Null Result ReportOpen accessAgricultural and Biological Sciences
Adam J. Bewick, Lexiang Ji, Chad E. Niederhuth et al. · 2016 · Proceedings of the National Academy of Sciences
In plants, CG DNA methylation is prevalent in the transcribed regions of many constitutively expressed genes (gene body methylation; gbM), but the origin and function of gbM remain unknown. Here we report the discovery that Eutrema…
View details →DOI: 10.1073/pnas.1604666113Cited by 352 Negative / Null Result ReportEarth and Planetary Sciences
Owen R. Cooper, R. S. Gao, D. W. Tarasick et al. · 2012 · Journal of Geophysical Research Atmospheres
This analysis provides an up‐to‐date assessment of long‐term (1990–2010) rural ozone trends using all available data in the western (12 sites) and eastern (41 sites) USA. Rather than focus solely on average ozone values or air quality…
View details →DOI: 10.1029/2012jd018261Cited by 352 Negative / Null Result ReportMedicine
C. Thanasas, George N. Papadimitriou, Charalambos Charalambidis et al. · 2011 · The American Journal of Sports Medicine
BACKGROUND: Chronic lateral elbow epicondylitis is a tendinosis with angiofibrolastic degeneration of the wrist extensors' origin. Healing of this lesion is reported with the use of autologous blood as well as with platelet-rich plasma…
View details →DOI: 10.1177/0363546511417113Cited by 351 Negative / Null Result ReportOpen accessAgricultural and Biological Sciences
A. M. S. A. Qados · 2011 · Journal of the Saudi Society of Agricultural Sciences
The effect of sodium chloride (NaCl) concentrations (0.0, 60, 120, 240 mM) on growth, osmotic potential, chlorophyll content, protein content of (Vicia faba L.) seedlings was investigated. NaCl caused an increase in plant height with low…
View details →DOI: 10.1016/j.jssas.2010.06.002Cited by 351 Negative / Null Result ReportSocial Sciences
Heather K. Spence Laschinger, Ashley L. Grau, Joan Finegan et al. · 2010 · Journal of Advanced Nursing
AIM: This paper is a report of a study conducted to test a model linking new graduate nurses' perceptions of structural empowerment to their experiences of workplace bullying and burnout in Canadian hospital work settings using Kanter's…
View details →DOI: 10.1111/j.1365-2648.2010.05420.xCited by 350 Negative / Null Result ReportOpen accessNeuroscience
Sebastian Cachero, Aaron D. Ostrovsky, Jai Y. Yu et al. · 2010 · Current Biology
BACKGROUND: Sex-specific behavior may originate from differences in brain structure or function. In Drosophila, the action of the male-specific isoform of fruitless in about 2000 neurons appears to be necessary and sufficient for many aspects of male courtship behavior. Initial work found limited evidence for anatomical dimorphism in these fru+ neurons. Subsequently, three discrete anatomical differences in central brain fru+ neurons have been reported, but the global organization of sex differences in wiring is unclear. RESULTS: A global search for structural differences in the Drosophila bra
View details →DOI: 10.1016/j.cub.2010.07.045Cited by 349 Replication FailureOpen accessDecision Sciences
Tom E Hardwicke, Maya B. Mathur, Kyle MacDonald et al. · 2018 · Royal Society Open Science
Access to data is a critical feature of an efficient, progressive and ultimately self-correcting scientific ecosystem. But the extent to which in-principle benefits of data sharing are realized in practice is unclear. Crucially, it is largely unknown whether published findings can be reproduced by repeating reported analyses upon shared data (‘analytic reproducibility’). To investigate this, we conducted an observational evaluation of a mandatory open data policy introduced at the journal Cognition . Interrupted time-series analyses indicated a substantial post-policy increase in data availabl
View details →DOI: 10.1098/rsos.180448Cited by 349 Negative / Null Result ReportMedicine
Joeli Marrero, Kyu Y. Rhee, Dirk Schnappinger et al. · 2010 · Proceedings of the National Academy of Sciences
Metabolic adaptation to the host niche is a defining feature of the pathogenicity of Mycobacterium tuberculosis (Mtb). In vitro, Mtb is able to grow on a variety of carbon sources, but mounting evidence has implicated fatty acids as the…
View details →DOI: 10.1073/pnas.1000715107Cited by 349 Negative / Null Result ReportOpen accessPhysics and Astronomy
M. M. Aggarwal, Z. Ahammed, A. V. Alakhverdyants et al. · 2010 · Physical Review Letters
We report the first measurements of the kurtosis ($\ensuremath{\kappa}$), skewness ($S$), and variance (${\ensuremath{\sigma}}^{2}$) of net-proton multiplicity (${N}_{p}\ensuremath{-}{N}_{\overline{p}}$) distributions at midrapidity for…
View details →DOI: 10.1103/physrevlett.105.022302Cited by 349 Negative / Null Result ReportOpen accessBusiness, Management and Accounting
Anders Gustafsson, Per Kristensson, Lars Witell · 2012 · Journal of service management
Purpose Customer co‐creation is becoming increasingly popular among companies, and intensive communication with customers is generally seen as a determinant of the success of a new service or product. The purpose of this study is to…
View details →DOI: 10.1108/09564231211248426Cited by 349 Negative / Null Result ReportOpen accessDecision Sciences
Hannah Fraser, Timothy Parker, Shinichi Nakagawa et al. · 2018 · PLoS ONE
We surveyed 807 researchers (494 ecologists and 313 evolutionary biologists) about their use of Questionable Research Practices (QRPs), including cherry picking statistically significant results, p hacking, and hypothesising after the results are known (HARKing). We also asked them to estimate the proportion of their colleagues that use each of these QRPs. Several of the QRPs were prevalent within the ecology and evolution research community. Across the two groups, we found 64% of surveyed researchers reported they had at least once failed to report results because they were not statistically
View details →DOI: 10.1371/journal.pone.0200303Cited by 349 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
David Habier, Rohan L. Fernando, Dorian J. Garrick · 2013 · Genetics
Genomic best linear unbiased prediction (BLUP) is a statistical method that uses relationships between individuals calculated from single-nucleotide polymorphisms (SNPs) to capture relationships at quantitative trait loci (QTL). We show…
View details →DOI: 10.1534/genetics.113.152207Cited by 349 Negative / Null Result ReportOpen accessMedicine
D. Robert Siemens, Sanoj Punnen, James M.W. Wong et al. · 2010 · BMC Medical Education
BACKGROUND: An observed decrease of physician scientists in medical practice has generated much recent interest in increasing the exposure of research programs in medical school. The aim of this study was to review the experience and attitudes regarding research by medical students in Canada. METHODS: An anonymous, cross-sectional, self-report questionnaire was administered to second and fourth year students in three medical schools in Ontario between February and May of 2005. Questions were primarily closed-ended and consisted of Likert scales. Descriptive and correlative statistics were used
View details →DOI: 10.1186/1472-6920-10-4Cited by 348 Negative / Null Result ReportOpen accessPhysics and Astronomy
Michael A. Kuhn, Lynne A. Hillenbrand, Alison Sills et al. · 2019 · The Astrophysical Journal
Abstract The Gaia mission has opened a new window into the internal kinematics of young star clusters at the sub-km s −1 level, with implications for our understanding of how star clusters form and evolve. We use a sample of 28 clusters…
View details →DOI: 10.3847/1538-4357/aaef8cCited by 347 Negative / Null Result ReportOpen accessMedicine
Robert F. Spetzler, Cameron G. McDougall, Felipe C Albuquerque et al. · 2013 · Journal of neurosurgery
OBJECT: The authors report the 3-year results of the Barrow Ruptured Aneurysm Trial (BRAT). The objective of this ongoing randomized trial is to compare the safety and efficacy of microsurgical clip occlusion and endovascular coil…
View details →DOI: 10.3171/2013.3.jns12683Cited by 347 