A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
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Michael A. Kuhn, Lynne A. Hillenbrand, Alison Sills et al. · 2019 · The Astrophysical Journal
Abstract The Gaia mission has opened a new window into the internal kinematics of young star clusters at the sub-km s −1 level, with implications for our understanding of how star clusters form and evolve. We use a sample of 28 clusters…
Ronald van den Berg, Edward Awh, Wei Ji · 2014 · Psychological Review
Three questions have been prominent in the study of visual working memory limitations: (a) What is the nature of mnemonic precision (e.g., quantized or continuous)? (b) How many items are remembered? (c) To what extent do spatial binding…
Andrew Gonzalez, Bradley J. Cardinale, Ginger Allington et al. · 2016 · Ecology
Global species extinction rates are orders of magnitude above the background rate documented in the fossil record. However, recent data syntheses have found mixed evidence for patterns of net species loss at local spatial scales. For…
Joachim von Pawel, Robert M. Jotte, David R. Spigel et al. · 2014 · Journal of Clinical Oncology
PURPOSE: Amrubicin, a third-generation anthracycline and potent topoisomerase II inhibitor, showed promising activity in small-cell lung cancer (SCLC) in phase II trials. This phase III trial compared the safety and efficacy of amrubicin…
John D. Meeker, Tiffany Yang, Xiaoyun Ye et al. · 2010 · Environmental Health Perspectives
BACKGROUND: Parabens are commonly used as antimicrobial preservatives in cosmetics, pharmaceuticals, and food and beverage processing. Widespread human exposure to parabens has been recently documented, and some parabens have demonstrated adverse effects on male reproduction in animal studies. However, human epidemiologic studies are lacking. OBJECTIVE: We investigated relationships between urinary concentrations of parabens and markers of male reproductive health in an ongoing reproductive epidemiology study. METHODS: Urine samples collected from male partners attending an infertility clinic
Julianne L. Holloway, Anthony M. Lowman, Giuseppe R. Palmese · 2012 · Soft Matter
The biocompatibility, processing ease, and mechanical properties of freeze-thawed poly(vinyl alcohol) (PVA)-based hydrogels have encouraged significant research toward developing this material for various biomedical applications.…
Stephen J. Nicholls, John J.P. Kastelein, Gregory G. Schwartz et al. · 2014 · JAMA
IMPORTANCE: Secretory phospholipase A2 (sPLA2) generates bioactive phospholipid products implicated in atherosclerosis. The sPLA2 inhibitor varespladib has favorable effects on lipid and inflammatory markers; however, its effect on…
Ji Young Bang, Udayakumar Navaneethan, Muhammad K. Hasan et al. · 2018 · Gut
OBJECTIVE: Although lumen-apposing metal stents (LAMS) are increasingly used for drainage of walled-off necrosis (WON), their advantage over plastic stents is unclear. We compared efficacy of LAMS and plastic stents for WON drainage.…
Manuel R. Agosín, Roberto Álvarez, Claudio Bravo‐Ortega · 2011 · World Economy
Abstract Using a large dataset for 79 countries covering the period 1962–2000, this study analyses the main determinants of export diversification (concentration). We explore the role of several factors and we use three different…
Ralph Peterli, Yves Borbély, Béatrice Kern et al. · 2013 · Annals of Surgery
In Brief Objective: Laparoscopic sleeve gastrectomy (LSG) has been proposed as an effective alternative to the current standard procedure, laparoscopic Roux-en-Y gastric bypass (LRYGB). Prospective data comparing both procedures are rare.…
Céline Michaud, Daniel Llerena · 2010 · Business Strategy and the Environment
Abstract Products' end‐of‐life management has recently become a critical business issue. One of the possible end‐of‐life strategies is remanufacturing, which can provide competitive advantages through material and energy savings. Beyond…
Hilal Daglar, Hasan Can Gülbalkan, Gökay Avcı et al. · 2021 · Angewandte Chemie International Edition
Abstract Development of computation‐ready metal–organic framework databases (MOF DBs) has accelerated high‐throughput computational screening (HTCS) of materials to identify the best candidates for gas storage and separation. These DBs…
Colin J. Carlson, Kevin R. Burgio, Eric R. Dougherty et al. · 2017 · Science Advances
Climate change is a well-documented driver of both wildlife extinction and disease emergence, but the negative impacts of climate change on parasite diversity are undocumented. We compiled the most comprehensive spatially explicit data set…
Anand Rohatgi, Marit Westerterp, Arnold von Eckardstein et al. · 2021 · Circulation
Low high-density lipoprotein cholesterol (HDL-C) characterizes an atherogenic dyslipidemia that reflects adverse lifestyle choices, impaired metabolism, and increased cardiovascular risk. Low HDL-C is also associated with increased risk of…
John Antoniadis, Zaven Arzoumanian, S. Babak et al. · 2021 · Monthly Notices of the Royal Astronomical Society
ABSTRACT We searched for an isotropic stochastic gravitational wave background in the second data release of the International Pulsar Timing Array, a global collaboration synthesizing decadal-length pulsar-timing campaigns in North…
Abel Brodeur, Nikolai Cook, Anthony Heyes · 2020 · American Economic Review
The credibility revolution in economics has promoted causal identification using randomized control trials (RCT), difference-in-differences (DID), instrumental variables (IV) and regression discontinuity design (RDD). Applying multiple…
Jennifer Alix‐Garcia, Elizabeth N. Shapiro, Katharine R. E. Sims · 2012 · Land Economics
We investigate a Mexican federal program that compensates landowners for forest protection. We use matched controls from the program applicant pool to establish counterfactual deforestation rates. Deforestation was reduced by 50% in…
Margaret A. Abernethy, Jan Bouwens, Laurence van Lent · 2014 · Minerva Access (University of Melbourne)
We investigate two determinants of two choices in the control system of divisionalized firms, namely decentralization and use of performance measures. The two determinants are those identified in the literature as important to control…
Ahmed Mushfiq Mobarak, Puneet Dwivedi, Rob Bailis et al. · 2012 · Proceedings of the National Academy of Sciences
Biomass combustion with traditional cookstoves causes substantial environmental and health harm. Nontraditional cookstove technologies can be efficacious in reducing this adverse impact, but they are adopted and used at puzzlingly low…
Jian Fang, Li Zhang, David Sutton et al. · 2012 · Journal of Nanomaterials
Polypropylene (PP) nanofibres have been electrospun from molten PP using a needleless melt‐electrospinning setup containing a rotary metal disc spinneret. The influence of the disc spinneret (e.g., disc material and diameter), operating parameters (e.g., applied voltage, spinning distance), and a cationic surfactant on the fibre formation and average fibre diameter were examined. It was shown that the metal material used for making the disc spinneret had a significant effect on the fibre formation. Although the applied voltage had little effect on the fibre diameter, the spinning distance affe
Aung Ko Win, Joanne Young, Noralane M. Lindor et al. · 2012 · Journal of Clinical Oncology
PURPOSE: To determine whether cancer risks for carriers and noncarriers from families with a mismatch repair (MMR) gene mutation are increased above the risks of the general population. PATIENTS AND METHODS: We prospectively followed a…
Yamina Pressler, John C. Moore, M. Francesca Cotrufo · 2018 · Oikos
Global fire regimes are shifting due to climate and land use changes. Understanding the responses of belowground communities to fire is key to predicting changes in the ecosystem processes they regulate. We conducted a comprehensive…
Joseph Cesario · 2014 · Perspectives on Psychological Science
Concerns have been raised recently about the replicability of behavioral priming effects, and calls have been issued to identify priming methodologies with effects that can be obtained in any context and with any population. I argue that…
Sung Soo Ahn, Myeong‐Jin Kim, Joon Seok Lim et al. · 2010 · Radiology
PURPOSE: To determine the added value of hepatobiliary phase images in gadoxetic acid-enhanced magnetic resonance (MR) imaging in the evaluation of hepatocellular carcinoma (HCC). MATERIALS AND METHODS: Institutional review board approved…
Ravi Jagannathan, Alexey Malakhov, Dmitry A. Novikov · 2010 · The Journal of Finance
ABSTRACT In measuring performance persistence, we use hedge fund style benchmarks. This allows us to identify managers with valuable skills, and also to control for option‐like features inherent in returns from hedge fund strategies. We…
Zhang Fei, Zheng Ge, Julien Grimaud et al. · 2013 · Environmental Science & Technology
Two 4 L tubular microbial fuel cells (MFCs) were installed in a municipal wastewater treatment facility and operated for more than 400 days on primary effluents. Both MFCs removed 65-70% chemical oxygen demand (COD) at a hydraulic…
Petros Aristodemou, Nathaniel E. Knox Cartwright, J M Sparrow et al. · 2010 · Journal of Cataract & Refractive Surgery
PURPOSE: To assess how intraocular lens (IOL) formula choice affects refractive outcomes after cataract surgery using IOLMaster biometry. SETTING: Department of Ophthalmology, Gloucestershire Hospitals NHS Foundation Trust, Cheltenham,…
Anna Piil Damm, Christian Dustmann · 2014 · American Economic Review
This paper investigates the effect of early exposure to neighborhood crime on subsequent criminal behavior of youth exploiting a unique natural experiment between 1986 and 1998 when refugee immigrants to Denmark were assigned to…
Richard P. Phillips, Ina C. Meier, Emily S. Bernhardt et al. · 2012 · Ecology Letters
A common finding in multiple CO(2) enrichment experiments in forests is the lack of soil carbon (C) accumulation owing to microbial priming of 'old' soil organic matter (SOM). However, soil C losses may also result from the accelerated…
Benjamin Haibe‐Kains, Christine Desmedt, Sherene Loi et al. · 2012 · JNCI Journal of the National Cancer Institute
BACKGROUND: Single sample predictors (SSPs) and Subtype classification models (SCMs) are gene expression-based classifiers used to identify the four primary molecular subtypes of breast cancer (basal-like, HER2-enriched, luminal A, and…