Serum Urate Lowering with Allopurinol and Kidney Function in Type 1 Diabetes
Alessandro Doria; Andrzej T. Gałecki; Cathie Spino; Rodica Pop‐Busui; David Z.I. Cherney; Ildiko Lingvay; Afshin Parsa; Peter Rossing · 2020 · New England Journal of Medicine
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
BACKGROUND: Higher serum urate levels are associated with an increased risk of diabetic kidney disease. Lowering of the serum urate level with allopurinol may slow the decrease in the glomerular filtration rate (GFR) in persons with type 1…
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Metadata source: OpenAlex · DOI 10.1056/nejmoa1916624