Negative / Null Result ReportOpen accessMedicine
Antonija Perović, Nora Nikolac, Marina Njire Bratičević et al. · 2017 · Biochemia Medica
INTRODUCTION: Scuba diving represents a combination of exercise and changes in environmental conditions. This study aimed to evaluate changes in haematological parameters after recreational scuba diving in order to identify clinically significant changes. MATERIALS AND METHODS: The study included males, 17 recreational divers, median age (range) 41 (30-52) years. Blood samples were taken before diving, immediately after diving to 30 meters for 30 minutes, 3 hours and 6 hours after diving. Complete blood counts were analyzed on the Cell Dyn Ruby haematology analyzer. Statistical significance be
View details →DOI: 10.11613/bm.2017.035Cited by 23 Negative / Null Result ReportOpen accessEconomics, Econometrics and Finance
Sascha Otto · 2011 · International Journal of Economics and Finance
We analyze the speculative efficiency of the six base metals traded at the London Metal Exchange (LME) for the post-Tin Crisis period from 1991-2008. Especially the influence of different futures contracts on the one side and different underlyings on the other side provides economic insights for market participants like hedgers and speculators. We focus on the 3-month and 15-month futures contracts for all six base metals and conduct single-contract test for every base metal applying an ARMA process. This system is expanded to the multi-contract case, modeling the forecast error as an ARMAX pr
View details →DOI: 10.5539/ijef.v3n1p3Cited by 23 Negative / Null Result ReportOpen accessNeuroscience
Klára Marečková, Amy Miles, Zhijie Liao et al. · 2022 · NeuroImage Clinical
BACKGROUND: Prenatal stress influences brain development and mood disorder vulnerability. Brain structural covariance network (SCN) properties based on inter-regional volumetric correlations may reflect developmentally-mediated shared…
View details →DOI: 10.1016/j.nicl.2022.102976Cited by 23 Negative / Null Result ReportEngineering
John Keane, Wei Zhang, Chris H. Kim · 2010
We present an array-based system to accurately study variations in ROSC aging. Microsecond measurements for minimal BTI recovery, and frequency shift measurement resolution ranging down to the error floor of 0.07% are achieved with three…
View details →DOI: 10.1109/iedm.2010.5703293Cited by 23 Negative / Null Result ReportOpen accessEarth and Planetary Sciences
E. M. Dunne, Lindsay Lee, Carly Reddington et al. · 2012 · Atmospheric chemistry and physics
Abstract. Observed correlations between short-term decreases in cosmic ray ionisation and cloud and aerosol properties have been attributed to short-term decreases in the ion-induced nucleation rate. We use a global aerosol microphysics model to determine whether a 10 day reduction of 15% in the nucleation rate could generate a statistically significant response in aerosol concentrations and optical properties. As an upper limit to the possible effect of changes in ion-induced nucleation rate, we perturb the total nucleation rate, which has been shown to generate particle concentrations and nu
View details →DOI: 10.5194/acp-12-11573-2012Cited by 23 Negative / Null Result ReportOpen accessMedicine
Freija Verdoodt, Susanne K. Kjær, Christian Dehlendorff et al. · 2018 · British Journal of Cancer
BACKGROUND: Increasing data suggest that aspirin use may improve cancer survival; however, the evidence is sparse for ovarian cancer. METHODS: We examined the association between postdiagnosis use of low-dose aspirin and mortality in a…
View details →DOI: 10.1038/bjc.2017.449Cited by 23 Negative / Null Result ReportOpen accessMedicine
Ping‐Hong Yeh, Sara M. Lippa, Tracey A. Brickell et al. · 2022 · Brain Communications
Abstract The purpose of this study was to analyze quantitative diffusion tensor imaging measures across the spectrum of traumatic brain injury severity and evaluate their trajectories in military service members. Participants were 96 U.S. military service members and veterans who had sustained a mild traumatic brain injury [including complicated mild traumatic brain injury (n = 16) and uncomplicated mild traumatic brain injury (n = 68)], moderate-severe traumatic brain injury (n = 12), and controls (with or without orthopaedic injury, n = 39). All participants had been scanned at least twice,
View details →DOI: 10.1093/braincomms/fcac132Cited by 23 Negative / Null Result ReportOpen accessMedicine
Tae‐Young Pak, Susana Ferreira, Gregory Colson · 2016 · Population Health Metrics
BACKGROUND: Because people care about their weight relative to peers and society, obesity inequality plays a role in explaining obesity incidence and the impacts of being obese on subjective well-being. While the increase in obesity prevalence and mean body mass index (BMI) is well documented, the measurement of distributional changes and corresponding obesity inequality is yet to be fully explored. METHODS: The present study analyzed BMI data for adults aged 20 to 74 from the National Health and Nutritional Examination Survey (NHANES) I (1971-1974), II (1976-1980), III (1988-1994), and contin
View details →DOI: 10.1186/s12963-016-0081-5Cited by 23 Negative / Null Result ReportOpen accessEngineering
Yaser Maddahi, Kourosh Zareinia, Liu Shi Gan et al. · 2016 · BioMed Research International
The use of robotic technology in the surgical treatment of brain tumour promises increased precision and accuracy in the performance of surgery. Robotic manipulators may allow superior access to narrow surgical corridors compared to freehand or conventional neurosurgery. This paper reports values and ranges of tool-tissue interaction forces during the performance of glioma surgery using an MR compatible, image-guided neurosurgical robot called neuroArm. The system, capable of microsurgery and stereotaxy, was used in the surgical resection of glioma in seven cases. neuroArm is equipped with for
View details →DOI: 10.1155/2016/9734512Cited by 23 Negative / Null Result ReportBiochemistry, Genetics and Molecular Biology
Bart de Boer · 2010 · Journal of Evolutionary Psychology
This paper investigates the effect of larynx position on the articulatory abilities of a human-like vocal tract. Previous work has investigated models that were built to resemble the anatomy of existing species or fossil ancestors. This…
View details →DOI: 10.1556/jep.8.2010.4.1Cited by 23 Negative / Null Result ReportOpen accessNeuroscience
Sean Coulborn, Howard Bowman, R. Chris Miall et al. · 2020 · Frontiers in Human Neuroscience
Mind-wandering is associated with switching our attention to internally directed thoughts and is by definition an intrinsic, self-generated cognitive function. Interestingly, previous research showed that it may be possible to modulate its propensity externally, with transcranial direct current stimulation (tDCS) targeting different regions in the default mode and executive control networks. However, these studies used highly heterogeneous montages (targeting the dorsolateral prefrontal cortex (DLPFC), the right inferior parietal lobule (IPL), or both concurrently), often showed contradicting
View details →DOI: 10.3389/fnhum.2020.00230Cited by 23 Negative / Null Result ReportOpen accessComputer Science
Christian Bock, Thomas Gumbsch, Michael Moor et al. · 2018 · Bioinformatics
Motivation: Most modern intensive care units record the physiological and vital signs of patients. These data can be used to extract signatures, commonly known as biomarkers, that help physicians understand the biological complexity of…
View details →DOI: 10.1093/bioinformatics/bty246Cited by 23 Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Juan Zeng, Yukun Li, Feifei Quan et al. · 2020 · Molecular Medicine Reports
Propofol, a commonly used intravenous anesthetic agent during surgery, has relatively widespread pharmacological actions. Previous studies have reported that propofol may act as an antitumor drug in several cancer types, such as pancreatic…
View details →DOI: 10.3892/mmr.2020.11223Cited by 23 Negative / Null Result ReportOpen accessMedicine
Francesca Faustini, Nicky Dunn, Nastya Kharlamova et al. · 2021 · Arthritis Research & Therapy
BACKGROUND: Anti-drug antibodies (ADAs) can impact on the efficacy and safety of biologicals, today used to treat several chronic inflammatory conditions. Specific patient groups may be more prone to develop ADAs. Rituximab is routinely used for ANCA-associated vasculitis (AAV) and as off-label therapy for systemic lupus erythematosus (SLE), but data on occurrence and predisposing factors to ADAs in these diseases is limited. OBJECTIVES: To elucidate the rate of occurrence, and risk factors for ADAs against rituximab in SLE and AAV. METHODS: ADAs were detected using a bridging electrochemilumi
View details →DOI: 10.1186/s13075-021-02589-6Cited by 23 Negative / Null Result Report
HAELIM PARK, PATRICK VAN HORN · 2015 · Journal of Money, Credit and Banking
We analyze the impact of contractionary monetary policy through increases in reserve requirements on bank lending. We compare the lending behavior of banks that were subject to the requirement increases in 1936–37, Federal Reserve member…
View details →DOI: 10.1111/jmcb.12235Cited by 23 Negative / Null Result ReportMedicine
Brintha K. Enestvedt, M. Brian Fennerty, A. Zaman et al. · 2011 · Alimentary Pharmacology & Therapeutics
BACKGROUND: In recent clinical trials (RCT) of bowel preparation, Golytely was more efficacious than MiraLAX. We hypothesised that there is a difference in adenoma detection between Golytely and MiraLAX. AIMS: To compare the adenoma…
View details →DOI: 10.1111/j.1365-2036.2011.04795.xCited by 23 Negative / Null Result ReportOpen accessMedicine
Mathias Roth, Christoph Holtmann, Loay Daas et al. · 2021 · Cornea
PURPOSE: Fungal keratitis (FK) is a serious ophthalmic disease with a potentially devastating outcome that seems to be increasing in recent years. The use of contact lenses (CLs) was evaluated as a risk factor for FK to determine possible…
View details →DOI: 10.1097/ico.0000000000002705Cited by 23 Negative / Null Result Report
Li Sian Goh · 2021 · Criminology & Public Policy
Research Summary Despite the widespread interest that de‐escalation training has attracted in law enforcement contexts over the past few years, we know little about its effectiveness in reducing use of force incidents. This study seeks to…
View details →DOI: 10.1111/1745-9133.12536Cited by 23 Negative / Null Result ReportOpen accessNeuroscience
A. V. Dyomina, Anna A. Kovalenko, Maria V. Zakharova et al. · 2022 · International Journal of Molecular Sciences
Metabotropic glutamate receptors (mGluRs) are expressed predominantly on neurons and glial cells and are involved in the modulation of a wide range of signal transduction cascades. Therefore, different subtypes of mGluRs are considered a promising target for the treatment of various brain diseases. Previous studies have demonstrated the seizure-induced upregulation of mGluR5; however, its functional significance is still unclear. In the present study, we aimed to clarify the effect of treatment with the selective mGluR5 antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]-pyridine (MTEP) on epile
View details →DOI: 10.3390/ijms23010497Cited by 23 Negative / Null Result ReportOpen accessMedicine
Nan Bi, Jun Liang, Zongmei Zhou et al. · 2019 · JAMA Network Open
Importance: Treatment of locally advanced non-small cell lung cancer (NSCLC) remains challenging. The rationale of combining a cyclooxygenase 2 (COX-2) inhibitor with concurrent chemoradiation (CCRT) was based on results of preclinical research and prospective clinical studies; however, no randomized clinical trial has provided evidence of a direct comparison with CCRT alone. Objective: To determine the effect of combined selective COX-2 inhibition with standard CCRT on survival among patients with unresectable stage III NSCLC. Design, Setting, and Participants: A single-center, open-label, ra
View details →DOI: 10.1001/jamanetworkopen.2019.18070Cited by 23 Negative / Null Result ReportOpen accessImmunology and Microbiology
Jayson L. Parker, Jillian Clare Köhler · 2010 · Journal of Pharmacy & Pharmaceutical Sciences
PURPOSE: To determine the risk of drug failure during clinical trial testing in Crohn's disease and determine what steps can be taken to improve outcomes. This is the first study to quantify such risk for a single disease. METHODS: Moderate to severe Crohn's disease was investigated by reviewing press releases from 1998 to June 2008. Clinical trial failure causes were classified as commercial or clinical and compared with industry expectations. The risk of failure was also reviewed based on whether the compound was a small molecule drug or a biologic. Lastly, the role of the sponsor was examin
View details →DOI: 10.18433/j39014Cited by 23 Negative / Null Result ReportOpen accessAgricultural and Biological Sciences
Lulu Yu, Yang Liu, Fei Xu · 2019 · BMC Plant Biology
BACKGROUND: Hydrogen cyanide (HCN) is a small gaseous molecule that is predominantly produced as an equimolar co-product of ethylene (ET) biosynthesis in plants. The function of ET is of great concern and is well studied; however, the function of HCN is largely unknown. Similar to ET, HCN is a simple and diffusible molecule that has been shown to play a regulatory role in the control of some metabolic processes in plants. Nevertheless, it is still controversial whether HCN should be regarded as a signalling molecule, and the cross-talk between HCN and ET in gene expression regulation remains u
View details →DOI: 10.1186/s12870-019-1690-5Cited by 23 Negative / Null Result ReportOpen accessMedicine
Kennichi Kakudo · 2022 · Cancers
Histopathological diagnosis of papillary thyroid carcinomas (PTCs) is prone to significant observer variation due to different thresholds of RAS-like nuclear changes among pathologists. This gap recently widened due to a defensive attitude by Western pathologists where malpractice litigation is significant. Cases with delicate RAS-like nuclear changes are follicular adenomas when they are noninvasive, follicular carcinomas when invasive, and follicular variant PTCs when they have fully developed PTC-type nuclear features in Asian practice. The different diagnostic threshold of PTC nuclear feat
View details →DOI: 10.3390/cancers14030812Cited by 23 Negative / Null Result Report
Jianjun Liu, Zhanqing Li · 2018 · Geophysical Research Letters
Abstract Aerosol optical quantities have been widely employed as the proxy variables of cloud condensation nuclei concentration to study aerosol indirect effects (AIE). Due to the aerosol swelling effect, cloud condensation nuclei and…
View details →DOI: 10.1029/2018gl077679Cited by 23 Negative / Null Result Report
Kenneth Button · 2012 · Transportation Journal
Abstract The article examines the sustainability of the low-cost, or no-frills, airline business model. It looks at the background to the development of this managerial approach within the context of some prevailing business theories and…
View details →DOI: 10.5325/transportationj.51.2.0197Cited by 23 Negative / Null Result ReportOpen accessMedicine
Wanlong Ma, Hagop M. Kantarjian, Ke Zhang et al. · 2010 · BMC Medical Genetics
BACKGROUND: Myelodysplastic syndrome (MDS) may be induced by certain mutagenic environmental or chemotherapeutic toxins; however, the role of susceptibility genes remains unclear. The G/G genotype of the single-nucleotide polymorphism (SNP) rs1617640 in the erythropoietin (EPO) promoter has been shown to be associated with decreased EPO expression. We examined the association of rs1617640 genotype with MDS. METHODS: We genotyped the EPO rS1617640 SNP in 189 patients with MDS, 257 with acute myeloid leukemia (AML), 106 with acute lymphoblastic leukemia, 97 with chronic lymphocytic leukemia, 353
View details →DOI: 10.1186/1471-2350-11-163Cited by 23 Negative / Null Result Report
Francisca Alves-Cardoso, Vanessa Campanacho · 2022 · Heritage
Advancements in digital technology have conquered a place in cultural heritage. The widespread use of three-dimensional scanners in bioanthropology have increased the production of 3D digital replicas of human bones that are freely…
View details →DOI: 10.3390/heritage5030085Cited by 23 Negative / Null Result Report
Panagiotis Kerezoudis, Kathleen J Yost, Nicole M Tombers et al. · 2018 · Neurosurgery
Abstract BACKGROUND The diagnosis of vestibular schwannomas (VS) is associated with reduced patient quality of life (QOL). Minimal clinically important difference (MCID) was introduced as the lowest improvement in a patient-reported…
View details →DOI: 10.1093/neuros/nyy467Cited by 23 Negative / Null Result Report
Jean C C Vila, Yang-Yu Liu, Alvaro Sanchez · 2020 · The ISME Journal
Abstract The taxonomic composition of microbial communities can vary substantially across habitats and within the same habitat over time. Efforts to build quantitative and predictive models of microbial population dynamics are underway,…
View details →DOI: 10.1038/s41396-020-0702-7Cited by 23 Negative / Null Result Report
Tao Zhang, Dan Gieseler, Rainer Jordan · 2016 · Polymer Chemistry
The influence of ambient laboratory light from common fluorescent lamps on AGET, ARGET, and classical ATRP reactions was investigated and significant differences were found except for ARGET ATRP.
View details →DOI: 10.1039/c5py01858gCited by 23 