The Success Rate of New Drug Development in Clinical Trials: Crohn’s Disease
Jayson L. Parker; Jillian Clare Köhler · 2010 · Journal of Pharmacy & Pharmaceutical Sciences
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
PURPOSE: To determine the risk of drug failure during clinical trial testing in Crohn's disease and determine what steps can be taken to improve outcomes. This is the first study to quantify such risk for a single disease. METHODS: Moderate to severe Crohn's disease was investigated by reviewing press releases from 1998 to June 2008. Clinical trial failure causes were classified as commercial or clinical and compared with industry expectations. The risk of failure was also reviewed based on whether the compound was a small molecule drug or a biologic. Lastly, the role of the sponsor was examin
Abstract by Jayson L. Parker; Jillian Clare Köhler, Journal of Pharmacy & Pharmaceutical Sciences (2010) — licensed CC BY 4.0.
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WASTE indexes this work — it does not host or republish it. Failure-type classification is automated and approximate.
Metadata source: OpenAlex · DOI 10.18433/j39014