A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
19735 results in Negative / Null Result Report · page 10 of 658
Leah B. Shapira, Myriam Mongrain · 2010 · The Journal of Positive Psychology
The effectiveness of two online exercises intended to help individuals experience (1) self-compassion (n = 63) and (2) optimism (n = 55) were compared to a control intervention where participants wrote about an early memory (n = 70). A…
Elizabeth Demers, Jurian Hendrikse, Philip Joos et al. · 2021 · Journal of Business Finance & Accounting
Abstract Environmental, social and governance (“ESG”) scores have been widely touted as indicators of share price resilience during the COVID‐19 crisis. Contrary to this conventional wisdom, we present robust evidence that once industry…
Deborah Carr, Vicki A. Freedman, Jennifer C. Cornman et al. · 2014 · Journal of Marriage and the Family
The authors examined associations between marital quality and both general life satisfaction and experienced (momentary) well‐being among older husbands and wives, the relative importance of own versus spouse's marital appraisals for…
Atif Mian, Amir Sufi · 2012 · The Quarterly Journal of Economics
Abstract We evaluate the impact of the 2009 Cash for Clunkers program on short- and medium-run auto purchases. Our empirical strategy exploits variation across U.S. cities in ex ante exposure to the program as measured by the number of…
Andra C. Ghent, Marianna Kudlyak · 2011 · Review of Financial Studies
We quantify the effect of recourse on default and find that recourse affects default by lowering the borrower's sensitivity to negative equity. At the mean value of the default option for defaulted loans, borrowers are 30% more likely to…
Bülent Sezen, Sibel Yıldız Çankaya · 2013 · Procedia - Social and Behavioral Sciences
Firms are facing growing pressure to become “greener” or more environmentally friendly. Consequently, firms have had to review their production processes as a result of pressures from the community and governments. This pilot study…
David T. Jones, Mary M. Machulda, Prashanthi Vemuri et al. · 2011 · Neurology
OBJECTIVE: To investigate age-related default mode network (DMN) connectivity in a large cognitively normal elderly cohort and in patients with Alzheimer disease (AD) compared with age-, gender-, and education-matched controls. METHODS: We…
Richard Anney, Lambertus Klei, Dalila Pinto et al. · 2012 · Human Molecular Genetics
While it is apparent that rare variation can play an important role in the genetic architecture of autism spectrum disorders (ASDs), the contribution of common variation to the risk of developing ASD is less clear. To produce a more…
Robert M. Kaplan, Veronica L. Irvin · 2015 · PLoS ONE
BACKGROUND: We explore whether the number of null results in large National Heart Lung, and Blood Institute (NHLBI) funded trials has increased over time. METHODS: We identified all large NHLBI supported RCTs between 1970 and 2012 evaluating drugs or dietary supplements for the treatment or prevention of cardiovascular disease. Trials were included if direct costs >$500,000/year, participants were adult humans, and the primary outcome was cardiovascular risk, disease or death. The 55 trials meeting these criteria were coded for whether they were published prior to or after the year 2000, wheth
Dawn Langan Teele, Joshua Kalla, Frances Rosenbluth · 2018 · American Political Science Review
This paper theorizes three forms of bias that might limit women's representation: outright hostility, double standards, and a double bind whereby desired traits present bigger burdens for women than men. We examine these forms of bias…
Michael T. Owyang, Valerie Ramey, Sarah Zubairy · 2013 · American Economic Review
A key question that has arisen during recent debates is whether government spending multipliers are larger during times when resources are idle. This paper seeks to shed light on this question by analyzing new quarterly historical data…
A. Sun, Kyounghwa Bae, Elizabeth Gore et al. · 2010 · Journal of Clinical Oncology
PURPOSE: There are scant data regarding the effects of prophylactic cranial irradiation (PCI) on neurocognitive function (NCF) and quality of life (QOL). Radiation Therapy Oncology Group trial 0214 showed no overall survival (OS) benefit…
Achille Schiavone, Michele De Marco, Silvia Martínez-Miró et al. · 2017 · Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology
The study aimed to determine the apparent total tract digestibility coefficients (ATTDC) of nutrients, the apparent metabolizable energy (AME and AMEn) and the amino acid (AA) apparent ileal digestibility coefficients (AIDC) of a partially defatted (BSFp) and a highly defatted (BSFh) black soldier fly larvae meal. The experimental diets were: a basal diet and two diets prepared by substituting 250 g/kg (w/w) of the basal diet with BSFp or BSFh, respectively. Significant differences were found between BSFp and BSFh meals for ATTDC of the nutrients: BSFp resulted more digestible than BSFh, excep
Cornelis Blauwendraat, Karl Heilbron, Costanza L. Vallerga et al. · 2019 · Movement Disorders
BACKGROUND: Increasing evidence supports an extensive and complex genetic contribution to PD. Previous genome-wide association studies (GWAS) have shed light on the genetic basis of risk for this disease. However, the genetic determinants…
Danny Rischin, Lester J. Peters, Brian O’Sullivan et al. · 2010 · Journal of Clinical Oncology
PURPOSE: Promising results in a randomized phase II trial with the hypoxic cytotoxin tirapazamine (TPZ) combined with cisplatin (CIS) and radiation led to this phase III trial. PATIENTS AND METHODS: Patients with previously untreated stage…
Denis Agniel, Isaac S. Kohane, Griffin M. Weber · 2018 · BMJ
OBJECTIVE: To evaluate on a large scale, across 272 common types of laboratory tests, the impact of healthcare processes on the predictive value of electronic health record (EHR) data. DESIGN: Retrospective observational study. SETTING:…
Charles Courtemanche, James Marton, Benjamin Ukert et al. · 2016 · Journal of Policy Analysis and Management
The Affordable Care Act (ACA) aimed to achieve nearly universal health insurance coverage in the United States through a combination of insurance market reforms, mandates, subsidies, health insurance exchanges, and Medicaid expansions,…
Saša Petrović, Miles Osborne, Victor Lavrenko · 2021 · Proceedings of the International AAAI Conference on Web and Social Media
Twitter is a very popular way for people to share information on a bewildering multitude of topics. Tweets are propagated using a variety of channels: by following users or lists, by searching or by retweeting. Of these vectors, retweeting…
Stephanie Cardarella, Atsuko Ogino, Mizuki Nishino et al. · 2013 · Clinical Cancer Research
PURPOSE: BRAF mutations are found in a subset of non-small cell lung cancers (NSCLC). We examined the clinical characteristics and treatment outcomes of patients with NSCLC harboring BRAF mutations. EXPERIMENTAL DESIGN: Using DNA…
Artur Strzelecki · 2023 · Innovative Higher Education
Abstract AI-powered chat technology is an emerging topic worldwide, particularly in areas such as education, research, writing, publishing, and authorship. This study aims to explore the factors driving students' acceptance of ChatGPT in higher education. The study employs the unified theory of acceptance and use of technology (UTAUT2) theoretical model, with an extension of Personal innovativeness, to verify the Behavioral intention and Use behavior of ChatGPT by students. The study uses data from a sample of 503 Polish state university students. The PLS-SEM method is utilized to test the mod
Ann Ganestam, Thomas Kallemose, Anders Troelsen et al. · 2015 · Knee Surgery Sports Traumatology Arthroscopy
The purpose of this study is to investigate the incidence of acute Achilles tendon rupture in Denmark from 1994 to 2013 with focus on sex, age, geographical areas, seasonal variation and choice of treatment. The National Patient Registry…
Hjördís Ósk Atladóttir, Tine Brink Henriksen, Diana Schendel et al. · 2012 · PEDIATRICS
OBJECTIVES: Results of animal studies suggest that maternal immune activation during pregnancy causes deficiencies in fetal neurodevelopment. Infectious disease is the most common path to maternal immune activation during pregnancy. The…
Velma T. E. Aho, Pedro A. B. Pereira, Sari Voutilainen et al. · 2019 · EBioMedicine
BACKGROUND: Several publications have described differences in cross-sectional comparisons of gut microbiota between patients with Parkinson's disease and control subjects, with considerable variability of the reported differentially…
May Al-Nbaheen, Radhakrishnan Vishnubalaji, Dalia Ali et al. · 2012 · Stem Cell Reviews and Reports
Human stromal (mesenchymal) stem cells (hMSCs) are multipotent stem cells with ability to differentiate into mesoderm-type cells e.g. osteoblasts and adipocytes and thus they are being introduced into clinical trials for tissue regeneration. Traditionally, hMSCs have been isolated from bone marrow, but the number of cells obtained is limited. Here, we compared the MSC-like cell populations, obtained from alternative sources for MSC: adipose tissue and skin, with the standard phenotype of human bone marrow MSC (BM-MSCs). MSC from human adipose tissue (human adipose stromal cells (hATSCs)) and h
Joseph Kan, Taichiro Morimoto, Kitichai Rungcharassaeng et al. · 2010 · PubMed
This study evaluated the reliability of assessing visually the facial gingival biotype of maxillary anterior teeth with and without the use of a periodontal probe in comparison with direct measurements. Forty-eight patients (20 men, 28…
Laura A. Pratt, Debra J. Brody, Qiuping Gu · 2011 · PubMed
In 2005–2008, 11% of Americans aged 12 and over took antidepressant medication. There were significant differences in antidepressant medication usage rates between groups. Females were 2½ times as likely as males to take antidepressants.…
Brian A. Boone, Mazen S. Zenati, Melissa E. Hogg et al. · 2015 · JAMA Surgery
IMPORTANCE: Quality assessment is an important instrument to ensure optimal surgical outcomes, particularly during the adoption of new surgical technology. The use of the robotic platform for complex pancreatic resections, such as the…
Valerie A. Earnshaw, Lisa A. Eaton, Seth C. Kalichman et al. · 2020 · Translational Behavioral Medicine
Conspiracy theories have been proliferating during the COVID-19 pandemic. Evidence suggests that belief in conspiracy theories undermines engagement in pro-health behaviors and support for public health policies. Moreover, previous work…
Andrew McArdle, Ortensia Vito, Harsita Patel et al. · 2021 · New England Journal of Medicine
BACKGROUND: Evidence is urgently needed to support treatment decisions for children with multisystem inflammatory syndrome (MIS-C) associated with severe acute respiratory syndrome coronavirus 2. METHODS: We performed an international…
Silke Langenheder, Anna J. Székely · 2011 · The ISME Journal
Many studies have shown that species sorting, that is, the selection by local environmental conditions is important for the composition and assembly of bacterial communities. On the other hand, there are other studies that could show that…