e-ISSN: Pending
Negative / Null Result ReportOpen accessMedicine· cited by 375

Phase III Trial of Prophylactic Cranial Irradiation Compared With Observation in Patients With Locally Advanced Non–Small-Cell Lung Cancer: Neurocognitive and Quality-of-Life Analysis

A. Sun; Kyounghwa Bae; Elizabeth Gore; Benjamin Movsas; Stuart J. Wong; Christina A. Meyers; James A. Bonner; Steven E. Schild · 2010 · Journal of Clinical Oncology

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract (excerpt)

PURPOSE: There are scant data regarding the effects of prophylactic cranial irradiation (PCI) on neurocognitive function (NCF) and quality of life (QOL). Radiation Therapy Oncology Group trial 0214 showed no overall survival (OS) benefit…

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Metadata source: OpenAlex · DOI 10.1200/jco.2010.29.6053