Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease
Lasse Folkersen; Eric B. Fauman; Maria Sabater‐Lleal; Rona J. Strawbridge; Mattias Frånberg; Bengt Sennblad; Damiano Baldassarre; Fabrizio Veglia · 2017 · PLoS Genetics
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Recent advances in highly multiplexed immunoassays have allowed systematic large-scale measurement of hundreds of plasma proteins in large cohort studies. In combination with genotyping, such studies offer the prospect to 1) identify mechanisms involved with regulation of protein expression in plasma, and 2) determine whether the plasma proteins are likely to be causally implicated in disease. We report here the results of genome-wide association (GWA) studies of 83 proteins considered relevant to cardiovascular disease (CVD), measured in 3,394 individuals with multiple CVD risk factors. We id
Abstract by Lasse Folkersen; Eric B. Fauman; Maria Sabater‐Lleal; Rona J. Strawbridge; Mattias Frånberg; Bengt Sennblad; Damiano Baldassarre; Fabrizio Veglia, PLoS Genetics (2017) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1371/journal.pgen.1006706