Negative / Null Result ReportOpen accessMedicine (General)
Manoochehr Nakhjavani, Firouzeh Asgarani, Fatemeh Esfahanian et al. · 2009 · Acta Medica Iranica
Accumulating evidence suggest that in patients with diabetes mellitus, increased rate of lipoprotein oxidation and oxidative stress have important role in diabetic angiopathy, including nephropathy. To evaluate the association of oxidized low- density lipoprotein (ox-LDL) with the development of diabetic nephropathy, plasma level of ox-LDL were measured in 70 diabetic patients with macro and 63 patients with normoalbuminuria. The plasma oxidized- LDL level in patients with macroalbuminuria was higher than those in normoalbuminuric group, (85.72 ± 32.92 mu/L versus 75.07 ± 26.46 u/L, P= 0.041).
View details →Negative / Null Result ReportOpen accessDentistry
Dewi Kania Intan Permatasari, Tenny Setiani Dewi, Dewi Marhaeni Diah Herawati · 2021 · Dental Journal
Background: Taste disorders often occur in the elderly, which can have serious consequences on their health status. Zinc and saliva volume have a role in maintaining taste acuity, especially in the elderly. Purpose: This study was to determine the correlation between salivary zinc levels, salivary volume, and taste disorders in elderly patients. Methods: This was a cross-sectional research. Elderly patients with and without taste disorders were included in this study. Salivary zinc levels were measured using the Atomic Absorption Spectrometry (AAS) method. Salivary volume was measured using th
View details →Negative / Null Result ReportOpen accessInfectious and parasitic diseases
Dou Qu, Xiaoni Zhong, Guiyuan Xiao et al. · 2018 · International Journal of Infectious Diseases
Objective: To evaluate adherence to pre-exposure prophylaxis (PrEP) in a clinical trial of a population of men who have sex with men (MSM), to explore the influence of social psychology and objective factors (e.g., forgetting, too busy) on adherence, and to provide evidence for subsequent PrEP research. Methods: This study analyzed the data from the daily medication group within a PrEP study (a randomized placebo-controlled trial of oral tenofovir among MSM in Western China from April 2013 to March 2015). A total of 331 participants were analyzed. PrEP adherence was self-reported by the subjec
View details →Negative / Null Result ReportOpen accessMedicine
Fatemeh Moghadasi-Boroujeni, Mansoureh Adel Ghahraman · 2020 · مجله پژوهش در علوم توانبخشی
Introduction: Romberg test is one of the balance screening tests. Since this test does not require special equipment, it is widely used in the evaluation of people suffering from balance disorders. This study aimed to determine the sensitivity of the Romberg test for the diagnosis of peripheral vestibular dysfunction compared with the caloric test that is the gold standard for the diagnosis of horizontal semicircular canal/superior vestibular nerve disorders.Materials and Methods: This study was a cross-sectional-comparative study and the sample was selected from those who referred to the audi
View details →Negative / Null Result ReportOpen accessMedicine (General)
Joel Del Bel Pádua, Carolline Fontes Alves Mariano, Alexandre Todorovic Fabro et al. · 2024 · Biomarker Insights
Background: Immunohistochemical prognostic significance of the homologous recombination-related proteins RAD51, ATM, BRCA1, and BRCA2 is known in gastric adenocarcinoma, one of the deadliest cancers. Objective and design: This retrospective cohort study aimed to evaluate mRNA expression and promoter methylation of some homologous recombination-related genes in this neoplasm. Methods: We evaluated mRNA expression and methylation of RAD51 , ATM , ATR , BRCA1 , and BRCA2 in tumor and non-tumor frozen samples from gastrectomy specimens by RT-qPCR and MS-HRM, correlating our results with previous i
View details →Negative / Null Result ReportOpen accessDiseases of the genitourinary system. Urology
Aves Editorial Aves Editorial · 2019 · Urology Research and Practice
Abstract Introduction: Lower urinary tract symptoms (LUTS) associated with BPH and erectile dysfunction (ED) are common problems in aging male. In this study, we aimed to determine the causes of the relationship between LUTS and ED, and the possible effects of body mass index (BMI), serum leptin, free testosterone (fT) and lipid levels on LUTS and ED etiology. Materials and Methods: Between June 2003 and February 2004, 46 patients were recruited in this study. All patients underwent physical examination including digital rectal examination, urine analysis, uroflowmetry and residual urine volum
View details →Negative / Null Result ReportOpen accessGynecology and obstetrics
Baumann Gert, Gericke Christine, Mueller Simone et al. · 2010 · BMC Women's Health
Abstract Background Decreased levels of circulating bone marrow-derived progenitor cells have been associated with risk factors and cardiovascular diseases. Smoking is the most important modifiable risk factor for atherosclerosis in young women. The aim of this pilot study was to assess in healthy premenopausal women without other risk factors for cardiovascular disease the influence of nicotine abuse on the number of circulating progenitor cells in relation to endothelial function. Methods The number of endothelial progenitor cells, measured as colony-forming units in a cell-culture assay (EP
View details →Negative / Null Result ReportOpen accessPsychiatry
Manik Changoji Bhise, Arun Vishwambhar Marwale, Ashish Chandrakantrao Mohide et al. · 2019 · Annals of Indian Psychiatry
Background: Survivors of suicide experience psychological distress for years after suicide. In India, farmers' suicide survivors are special group, with unique set of stressors. There are very few studies examining this group in India. The objective was to assess psychological distress and its correlates in survivors of farmers' suicides. Methods: This was a cross-sectional study from two districts of Marathwada region of Maharashtra. A predesigned and pretested semi-structured questionnaire to assess sociodemographic variables was used. Self-reporting questionnaire-20 was administered to eval
View details →Negative / Null Result ReportOpen accessElectrical engineering. Electronics. Nuclear engineering
Florinda F. Martins, Hélio Castro · 2020 · Energy Reports
Nowadays the production systems are linear and the consumption patterns are essentially based on products with a short life cycle, which contribute to increase the demand for raw materials and environmental impacts. The Circular Economy (CE) is playing a major role among scholars and practitioners. Many aspects are now defining this new trending paradigm such as the roles of product development, transformation and remanufacturing/recycling, and/or management of waste, ensuring the economic and environmental benefits. The increasing demand causes instability of the prices and markets, and there
View details →Negative / Null Result ReportOpen accessNutrition. Foods and food supply
Ines Farah KANFOUD, Ibrahim SERSAR, Meriem BENCHARIF et al. · 2026 · Revista Española de Nutrición Humana y Dietética
Introduction: Adopting good nutritional practices and strategies can be attributed to a better understanding of dietary knowledge and habits, thus promoting good sports performance. This study aimed to assess athletes' nutritional knowledge, eating habits, and adherence to the Mediterranean diet. Methodology: Cross-sectional survey of 70 adult athletes. Data were collected using a questionnaire assessing their eating habits, nutritional knowledge (Abridged Nutrition for Sport Knowledge Questionnaire, A-NSKQ), and adherence to the Mediterranean diet (Medi-Lite score). Statistical analyses were
View details →Negative / Null Result ReportOpen accessSports medicine
Rika Kimoto, Isao Kambayashi, Akane Akizuki et al. · 2021 · Journal of Physical Fitness and Sports Medicine
The autonomic nervous system (ANS) maintains homeostasis through the balance of the sympathetic and parasympathetic subsystems or divisions. Currently, analysis of heart rate variability (HRV) offers an indirect, non-invasive assessment of ANS function. An irregular lifestyle and stress are known to affect ANS balance, influencing many diseases. Moreover, ANS disorder plays an important role in climacteric symptoms in menopausal females. The purpose of this study was designed to assess the effects of yoga practice sessions (herein referred to as “yoga”) on ANS function and focused on the relat
View details →Negative / Null Result ReportOpen accessDentistry
Kavita Hotwani, Krishna Sharma, Arpan Jaiswal · Dental Press Journal of Orthodontics
ABSTRACT Objective: The present study was an attempt to investigate tongue/mandible volume ratio in children, using volumetric magnetic resonance imaging (MRI) for early screening and to aid in treatment planning. Methods: Volumetric evaluation of tongue volume/mandible volume ratio (TV/MV ratio) in children with obstructive sleep apnea (OSA) using MRI was carried out retrospectively on available DICOM MR images of children in the age group of 10-14 years. MRI image records of patients diagnosed with OSA were obtained from interventional radiology department records, at Sharad Pawar Dental Col
View details →Negative / Null Result ReportOpen accessMedicine
Tiara Sekar Ayudhipasha, Menik Herdwiyanti, Sedayu Sedayu · 2025 · GHMJ (Global Health Management Journal)
Background: West Java ranks the highest Province with Human Immunodeficiency Virus (HIV) case in 2023. An estimated 1.648 patients estimated receive antiretroviral therapy (ART). Kidney disease contributes mortality amongst people living with HIV/AIDS (PLWH). Tenofovir disoproxil fumarate (TDF)-based ART was associated as risk factor of kidney disorders, indicate by declining glomerular filtration rate (GFR). However, there is limited study whether kidney disease among PLWH were related to ART use in Indonesia. Aims: To determine correlation between duration of antiretroviral therapy and glome
View details →Negative / Null Result ReportOpen accessPediatrics
Nevzat Gönder, Cansu Öztürk, Rabia Taşdemir et al. · 2025 · Children
Background: A precise radiographic evaluation of adolescent idiopathic scoliosis (AIS) is essential for effective treatment planning and follow-up. The pelvic axial rotation (PAR) and horizontal balance of the pelvis are critical factors to consider throughout the treatment and monitoring of AIS. While some previous studies have examined spinal curvature in relation to PAR direction and the direction of the major curve (DMC) in AIS patients, this study aims to explore the relationship between scoliosis morphology, pelvic axial rotation (PAR), and the direction of the major curve in patients wi
View details →Negative / Null Result ReportOpen accessMedicine
Derya Koyun, Gokhan Nergizoglu, Kemal Metin Kir · 2018 · Saudi Journal of Kidney Diseases and Transplantation
The loss of muscle mass and cachexia is commonly seen in hemodialysis (HD) patients and contribute to morbidity and mortality. The exact mechanism of this fact is multifactorial and still unclear. Myostatin, a transforming growth factor-ß family ligand, is released from the skeletal and heart muscle and may be responsible for muscle degradation and atrophy. The aim of this study is evaluation of the relationship between muscle mass and serum myostatin level in chronic HD patients. One hundred and forty HD patients (79 males, 28 diabetic, mean age; 53.96 ± 13.6) were included in this cross-sect
View details →Negative / Null Result ReportOpen accessHistory of scholarship and learning. The humanities
Lalić Bojan R., Ranđelović Dušan J. · 2013 · Zbornik Radova Filozofskog Fakulteta u Prištini
The aim of this research was to identify relations between level of religiosity and level of contact on one side and social attitudes towards members of religious out-groups in conflict environment on the other side. This research was conducted on the sample of Christian Orthodox students in Kosovska Mitrovica (which is partially conflict environment) and the Muslims were the out-group towards whom attitudes were analyzed. Attitudes measures we used were social distance scale and semantic differential. Likert type scale was used for religiosity measure, quantity and quality of contact. Control
View details →Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens
Inga Marte Charlott Seuthe, Markus Ruwe, Franz Mitze et al. · 2025 · Discover Oncology
Abstract Objectives VCP/p97 inhibition is known to upregulate PD-L1. This study investigated the correlation between PD-L1 and VCP/p97 expression in OPSCC, as well as the expression and prognostic significance of VCP/p97 in OPSCC. Methods The study retrospectively included 56 patients with OPSCC. Immunohistochemical staining was performed to detect VCP/p97 and PD-L1 expression. The staining intensity of VCP/p97 and PD-L1 TPS and CPS was determined. HPV status was evaluated using immunohistochemical staining against p16 and HPV PCR. In addition, iTILs were assessed. Results High VCP/p97 express
View details →Negative / Null Result ReportOpen accessVeterinary medicine
Erica Anna Gumpert Herlofson, Francesca Tavola, Karolina Siri Engdahl et al. · 2023 · Acta Veterinaria Scandinavica
Abstract Background Pre-emptive local analgesia with the use of lidocaine is practised increasingly in veterinary medicine as part of applied multimodal analgesia, despite its controversial impact on wound healing. The purpose of this prospective, randomised, double-blinded, placebo-controlled clinical study was to evaluate if preoperative subcutaneous infiltration of lidocaine has a negative impact on primary wound healing of surgical incisions. Fifty-two companion animals (3 cats and 49 dogs) were enrolled in the study. The inclusion criteria were as follows: American Society of Anaesthesiol
View details →Negative / Null Result ReportOpen accessAgriculture
Yosuke Kuroda, Kazuyuki Okazaki, Kenji Takashino et al. · 2025 · Agrosystems, Geosciences & Environment
Abstract Sugar beet (Beta vulgaris) production in Japan faces major challenges from virus yellows (VY), caused by beet leaf yellowing virus (BLYV) and transmitted by aphids. Outbreaks have reduced sugar yields, and breeding for tolerant varieties has not been conducted in Japan. This study marks the first step toward developing VY‐tolerant varieties by testing three hypotheses: (1) leaf yellowing can be induced by artificial inoculation, (2) tolerance varies among breeding materials, and (3) differences in tolerance to yellowing disease can be evaluated. From 2017 to 2020, four sugar beet mate
View details →Negative / Null Result ReportOpen accessTherapeutics. Pharmacology
Kun Wang, Yuanyuan Shen, Chen Hu et al. · 2025 · Clinical and Translational Science
ABSTRACT While PD‐L1 antibodies have demonstrated efficacy in small cell lung cancer, the therapeutic benefits remain limited. To address this unmet medical need, serplulimab was developed as an innovative monoclonal antibody targeting PD‐1. This study evaluated the pharmacokinetic (PK) properties of serplulimab and their relationship with efficacy and safety in patients with extensive‐stage small cell lung cancer (ES‐SCLC), using population pharmacokinetics (PopPK) and exposure–response (E–R) analysis to inform dose selection. Data from 1144 patients across eight Phase I–III clinical trials s
View details →Negative / Null Result ReportOpen accessMedicine
Ni Luh Kadek Alit Arsani, Luh Ari Arini, Luh Yenny Armayanti et al. · 2026 · Althea Medical Journal
Background: During perimenopause, declining estrogen levels often lead to altered menstrual patterns and other age-related health concerns. Consequently, the role of physical activity warrants closer examination. This study investigated the correlation between exercise frequency and menstrual cycle characteristics in premenopausal women Methods: A cross-sectional observational study was conducted in Singaraja City, Indonesia, from July to October 2024. A total of 150 premenopausal women aged 45–50 years were recruited through random sampling. Exercise frequency was measured using the World Hea
View details →Negative / Null Result ReportOpen accessVeterinary medicine
Kimberly Williams, Valerie MacDonald-Dickinson, Arata Matsuyama · 2024 · Journal of Feline Medicine and Surgery
Objectives This retrospective study aimed to determine the incidence and trends of proteinuria, elevations in serum creatinine and urea, and systolic blood pressure in cats undergoing treatment with toceranib. Methods In total, 32 cats treated with toceranib for malignancies were analyzed. Cats were included if urinalysis and urine protein:creatinine ratio (UPC) measurements were available at 28 days (T1) and 56 days (T2) after starting the treatment. Cats with concurrent lower urinary tract disease, including urinary tract malignancy, were excluded. Friedman’s ANOVA compared variables between
View details →Negative / Null Result ReportOpen accessMedicine
Yayuan Deng, Hongxuan Wu, Tingning Zhao et al. · 2025 · Scientific Reports
Abstract Atmospheric dustfall is solid air pollutant, which is mainly influenced by local sources, so it has a major impact on the local environment and the health of local residents. The objective of this study was to investigate the distribution characteristics of dustfall fluxes and particle size, and the meteorological factors affected them. Atmospheric dustfall was collected in an open-pit coal mining area and surrounding areas in the arid desert area of Northwest China from March to December 2018. Dustfall fluxes was measured, particle size was measured by using graphical methods and gra
View details →Negative / Null Result ReportOpen accessDiseases of the musculoskeletal system
Nicola Manta, Laura Mangiavini, Cristiana Balbino et al. · 2021 · BMC Musculoskeletal Disorders
Abstract Background Suction drainage is commonly applied after total knee arthroplasty (TKA) and unicompartmental knee arthroplasty (UKA) to reduce hematoma, swelling and to favor surgical wound healing. However, its efficacy remains controversial; thus, the purpose of this study is to evaluate drainage efficiency in the management of postoperative bleeding in TKA and UKA. Methods The cohort comprised 134 clinical records of patients affected by knee osteoarthritis (OA) who underwent either TKA or UKA. All the patients were subdivided into 2 groups: the first one with drainage and the second o
View details →Negative / Null Result ReportOpen accessVeterinary medicine
Evangelia Maniaki, Carmen Pineda, Angie Hibbert et al. · 2024 · Frontiers in Veterinary Science
ObjectivesThis case-control study aimed to evaluate calcitonin response in naturally occurring hypercalcemia in cats and assess the relationships between calcitonin and ionized calcium (iCa) and examine relationships between calcitonin, iCa and bone turnover.MethodsHypercalcemic cats (persistently increased iCa concentration [>1.40 mmol/l]) were identified retrospectively via a medical database search; additional hypercalcemic and normocalcemic cats were recruited prospectively. Data regarding routine biochemical and urine testing, diagnostic imaging and additional blood testing were obtained.
View details →Negative / Null Result ReportOpen accessMedicine
M. Kivikko, P. Pollesello, Tuukka Tarvasmäki et al. · 2016 · International Journal of Cardiology
BACKGROUND In the SURVIVE trial, including 1327 acute heart failure patients, no statistically significant difference between levosimendan and dobutamine in the 180-day all-cause mortality was seen. Country-specific differences in outcome…
View details →Negative / Null Result ReportOpen accessMedicine
V. Wadhwan, Preeti Sharma, Chitrapriya Saxena et al. · 2015 · Indian Journal of Dental Research
CONTEXT Like normal tissues, tumors require an adequate supply of oxygen, metabolites and an effective way to remove waste products. This is achieved by angiogenesis, which is defined as the process by which new blood vessels are produced…
View details →Negative / Null Result ReportOpen access
Ali Md. Yeakub, Fatimah Md. Yusoff, Natrah Fatin Mohd. Ikhsan et al. · 2023 · Pertanika Journal of Tropical Agricultural Science
Marine fish larvae are an integral part of the marine environment because their abundance can become an ecological indicator. The abundance is dependent on the environmental variations that include but are not limited to lunar phases and…
View details →Negative / Null Result ReportOpen accessMedicine
S. Lipshultz, Paige L. Williams, B. Zeldow et al. · 2015 · AIDS (London)
Objectives:We evaluated the potential cardiac effects of in-utero exposures to antiretroviral drugs in HIV-exposed but uninfected (HEU) children. Design and methods:We compared echocardiographic parameters of left ventricular function…
View details →Negative / Null Result ReportMedicine
James K. Gabriels, M. Abdelrahman, Lakshmi Nambiar et al. · 2021 · Heart Rhythm
BACKGROUND Electrocardiographic (ECG) criteria have been proposed to localize the site of origin (SOO) of outflow region ventricular arrhythmias (VAs). Many factors influence the QRS morphology of VAs and may limit the accuracy of these…
View details →