mRNA Expression and Methylation of the , , , , and Genes in Gastric Adenocarcinoma
Joel Del Bel Pádua; Carolline Fontes Alves Mariano; Alexandre Todorovic Fabro; Fermino Sanches Lizarte Neto; Rogério Lenotti Zuliani; Cláudia Tarcila Gomes Sares; José Sebastião dos Santos; Ajith Kumar Sankarankutty · 2024 · Biomarker Insights
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Background: Immunohistochemical prognostic significance of the homologous recombination-related proteins RAD51, ATM, BRCA1, and BRCA2 is known in gastric adenocarcinoma, one of the deadliest cancers. Objective and design: This retrospective cohort study aimed to evaluate mRNA expression and promoter methylation of some homologous recombination-related genes in this neoplasm. Methods: We evaluated mRNA expression and methylation of RAD51 , ATM , ATR , BRCA1 , and BRCA2 in tumor and non-tumor frozen samples from gastrectomy specimens by RT-qPCR and MS-HRM, correlating our results with previous i
Abstract by Joel Del Bel Pádua; Carolline Fontes Alves Mariano; Alexandre Todorovic Fabro; Fermino Sanches Lizarte Neto; Rogério Lenotti Zuliani; Cláudia Tarcila Gomes Sares; José Sebastião dos Santos; Ajith Kumar Sankarankutty, Biomarker Insights (2024) — licensed CC BY 4.0.
About to run something similar?
Run an AI Precheck on your own design to catch failure modes like this one before you spend the time. Your first desk check is free.
Related failures
MULLIGAN VERSUS MAITLAND MOBILIZATION ON THORACIC KYPHOTIC ANGLE IN POSTURAL KYPHOSIS
Negative / Null Result ReportRelationship between Dietary Acid Load and Glioma: A Case-Control Study
Negative / Null Result ReportTUDCA promotes intracellular clearance of Burkholderia pseudomallei by inhibiting endoplasmic reticulum stress-induced apoptosis in RAW264.7 cells
Negative / Null Result ReportEffect of High-Intensity Focused Ultrasound on sleep quality measures in obese doubled chin women: a randomized controlled trial
Negative / Null Result ReportDo Preferred Risk Formats Lead to Better Understanding? A Multicenter Controlled Trial on Communicating Familial Breast Cancer Risks Using Different Risk Formats
Negative / Null Result ReportThe Effect of Combined Exercise Training and Feroglobin Supplementation on Serum Iron and Lipid Profile in Women with Iron Deficiency Anemia
WASTE indexes this work — it does not host or republish it. Failure-type classification is automated and approximate.
Metadata source: DOAJ · DOI 10.1177/11772719231225206